The network for 'regulation of antimicrobial humoral response' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of antimicrobial humoral response

Any process that modulates the frequency, rate, or extent of an antimicrobial humoral response.

Mus musculus
Name Description Probability Func Analog Organism
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 1.000
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 1.000
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 1.000
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 1.000
Tnf tumor necrosis factor 0.998
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.997
Ikbkg inhibitor of kappaB kinase gamma 0.987
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.979
Ikbkb inhibitor of kappaB kinase beta 0.967
Lyz2 lysozyme 2 0.956
Ikzf1 IKAROS family zinc finger 1 0.913
Stat5b signal transducer and activator of transcription 5B 0.906
Trp53 transformation related protein 53 0.901
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.898
Il4ra interleukin 4 receptor, alpha 0.897
Stat5a signal transducer and activator of transcription 5A 0.886
Gata4 GATA binding protein 4 0.884
Fos FBJ osteosarcoma oncogene 0.840
Myd88 myeloid differentiation primary response gene 88 0.747
Rxra retinoid X receptor alpha 0.722
Il2rg interleukin 2 receptor, gamma chain 0.719
Stat3 signal transducer and activator of transcription 3 0.691
Mapk14 mitogen-activated protein kinase 14 0.691
Tlr4 toll-like receptor 4 0.663
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.606
Socs1 suppressor of cytokine signaling 1 0.581
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.564
Pycard PYD and CARD domain containing 0.505
Socs3 suppressor of cytokine signaling 3 0.444
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.442
Fas Fas (TNF receptor superfamily member 6) 0.440
Pax2 paired box gene 2 0.402
Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.396
Zfp36 zinc finger protein 36 0.391
Nkx2-3 NK2 transcription factor related, locus 3 (Drosophila) 0.386
Il1b interleukin 1 beta 0.376
Tnip1 TNFAIP3 interacting protein 1 0.374
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.369
Irf1 interferon regulatory factor 1 0.367
Mapk11 mitogen-activated protein kinase 11 0.361
Neurog2 neurogenin 2 0.329
Tgfb1 transforming growth factor, beta 1 0.315
Igh immunoglobulin heavy chain complex 0.299
Cyld cylindromatosis (turban tumor syndrome) 0.284
Mapkapk2 MAP kinase-activated protein kinase 2 0.284
Nlrp3 NLR family, pyrin domain containing 3 0.284
Rel reticuloendotheliosis oncogene 0.279
Bcl6 B-cell leukemia/lymphoma 6 0.269
Il1r1 interleukin 1 receptor, type I 0.267
Atf3 activating transcription factor 3 0.253
Foxp3 forkhead box P3 0.251
Hand2 heart and neural crest derivatives expressed transcript 2 0.240
Cdx2 caudal type homeobox 2 0.234
Cd40 CD40 antigen 0.225
Atf2 activating transcription factor 2 0.223
Nfil3 nuclear factor, interleukin 3, regulated 0.220
Mknk2 MAP kinase-interacting serine/threonine kinase 2 0.211
Per1 period homolog 1 (Drosophila) 0.209
Bcl3 B-cell leukemia/lymphoma 3 0.205
Birc3 baculoviral IAP repeat-containing 3 0.197
Cd44 CD44 antigen 0.181
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.180
Ccl4 chemokine (C-C motif) ligand 4 0.167
Nfkbiz nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.166
Il2 interleukin 2 0.166
Il18 interleukin 18 0.160
Nckap1l NCK associated protein 1 like 0.157
Casp1 caspase 1 0.153
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.150
Gata5 GATA binding protein 5 0.150
Mta1 metastasis associated 1 0.146
Nfkbie nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.144
Ticam1 toll-like receptor adaptor molecule 1 0.141
2010106G01Rik RIKEN cDNA 2010106G01 gene 0.135
Rag2 recombination activating gene 2 0.130
Dlx1 distal-less homeobox 1 0.128
Gbp2 guanylate binding protein 2 0.125
Hoxd13 homeobox D13 0.125
Mesp1 mesoderm posterior 1 0.125
Il10 interleukin 10 0.120
2410004A20Rik RIKEN cDNA 2410004A20 gene 0.116
Trp73 transformation related protein 73 0.115
Wnt6 wingless-related MMTV integration site 6 0.113
Dusp1 dual specificity phosphatase 1 0.113
Traf6 TNF receptor-associated factor 6 0.109
Sfpi1 SFFV proviral integration 1 0.103
Xrcc1 X-ray repair complementing defective repair in Chinese hamster cells 1 0.102
Rara retinoic acid receptor, alpha 0.101
Hsf1 heat shock factor 1 0.100
Cdx1 caudal type homeobox 1 0.099
Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.097
Cry2 cryptochrome 2 (photolyase-like) 0.097
Junb Jun-B oncogene 0.097
Rhob ras homolog gene family, member B 0.096
Hmx3 H6 homeobox 3 0.095
Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.090
Egr1 early growth response 1 0.089
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.089
Nr0b2 nuclear receptor subfamily 0, group B, member 2 0.088
Ier2 immediate early response 2 0.088
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Rel Relish 0.999
PGRP-LC Peptidoglycan recognition protein LC 0.948
Spn27A Serpin 27A 0.868
SPE Spatzle-Processing Enzyme 0.828
grass Gram-positive Specific Serine protease 0.808
AttA Attacin-A 0.726
Dredd Death related ced-3/Nedd2-like protein 0.711
ird5 immune response deficient 5 0.661
Spn28D Serpin 28D 0.628
PGRP-SD CG7496 gene product from transcript CG7496-RA 0.601
imd immune deficiency 0.563
Mtk Metchnikowin 0.544
spz spatzle 0.518
PGRP-SA Peptidoglycan recognition protein SA 0.493
Mpk2 CG5475 gene product from transcript CG5475-RB 0.358
ird1 immune response deficient 1 0.332
PGRP-SC1a CG14746 gene product from transcript CG14746-RA 0.308
Tak1 TGF-beta activated kinase 1 0.303
Myd88 CG2078 gene product from transcript CG2078-RA 0.287
AGO2 Argonaute 2 0.284
sno strawberry notch 0.280
fon fondue 0.268
Irc Immune-regulated catalase 0.266
BG4 CG12297 gene product from transcript CG12297-RA 0.244
Glt Glutactin 0.244
Spn1 Serine protease inhibitor 1 0.235
ush u-shaped 0.202
key kenny 0.190
modSP modular serine protease 0.188
CG32185 CG32185 gene product from transcript CG32185-RA 0.182
CG15917 CG15917 gene product from transcript CG15917-RA 0.163
IM18 Immune induced molecule 18 0.161
Sp7 Serine protease 7 0.158
psh persephone 0.158
PGRP-LF Peptidoglycan recognition protein LF 0.151
pirk poor Imd response upon knock-in 0.144
PGRP-LB Peptidoglycan recognition protein LB 0.130
Ndae1 Na[+]-driven anion exchanger 1 0.122
CG5390 CG5390 gene product from transcript CG5390-RA 0.119
gpp grappa 0.119
osa CG7467 gene product from transcript CG7467-RD 0.117
GNBP3 Gram-negative bacteria binding protein 3 0.116
CG18594 CG18594 gene product from transcript CG18594-RA 0.114
DptB Diptericin B 0.113
Traf6 TNF-receptor-associated factor 6 0.108
tld tolloid 0.097
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.092
nmo nemo 0.091
eg eagle 0.090
Pvr PDGF- and VEGF-receptor related 0.088
egr eiger 0.082
CG9184 CG9184 gene product from transcript CG9184-RB 0.081
eater CG6124 gene product from transcript CG6124-RB 0.081
amos absent MD neurons and olfactory sensilla 0.077
slp1 sloppy paired 1 0.076
p38b CG7393 gene product from transcript CG7393-RA 0.074
nub nubbin 0.070
tup tailup 0.069
sc scute 0.066
CG7910 CG7910 gene product from transcript CG7910-RA 0.066
CG11286 CG11286 gene product from transcript CG11286-RA 0.066
PGRP-SC1b CG8577 gene product from transcript CG8577-RA 0.065
tamo CG4057 gene product from transcript CG4057-RA 0.063
px plexus 0.062
CycD Cyclin D 0.061
bcd bicoid 0.059
CG12766 CG12766 gene product from transcript CG12766-RA 0.058
vir virilizer 0.057
tna tonalli 0.052
Ark Apaf-1-related-killer 0.052
Traf4 TNF-receptor-associated factor 4 0.052
Tsp42Ef Tetraspanin 42Ef 0.051
Tab2 TAK1-associated binding protein 2 0.051
CG17633 CG17633 gene product from transcript CG17633-RA 0.050
Mekk1 CG7717 gene product from transcript CG7717-RB 0.048
Atg18 Autophagy-specific gene 18 0.048
l(3)mbn lethal (3) malignant blood neoplasm 0.048
cact cactus 0.048
spheroide CG9675 gene product from transcript CG9675-RA 0.047
lin lines 0.047
Toll-7 CG8595 gene product from transcript CG8595-RA 0.047
dx deltex 0.046
TepIII Thiolester containing protein III 0.046
CG8586 CG8586 gene product from transcript CG8586-RA 0.046
ac achaete 0.045
th thread 0.045
Gef64C Guanine nucleotide exchange factor GEF64C 0.045
foxo forkhead box, sub-group O 0.044
raw CG12437 gene product from transcript CG12437-RB 0.044
stau staufen 0.043
os outstretched 0.042
CG9372 CG9372 gene product from transcript CG9372-RA 0.042
upd3 unpaired 3 0.041
GNBP1 Gram-negative bacteria binding protein 1 0.039
Trx-2 thioredoxin-2 0.038
18w 18 wheeler 0.038
CG13641 CG13641 gene product from transcript CG13641-RA 0.038
Drs Drosomycin 0.038
HLHmgamma E(spl) region transcript mgamma 0.036
upd2 unpaired 2 0.036
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Homo sapiens
Name Description Probability Func Analog Organism
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 1.000
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.994
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.985
REL v-rel reticuloendotheliosis viral oncogene homolog (avian) 0.983
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.942
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.937
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.921
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.911
BCL3 B-cell CLL/lymphoma 3 0.804
TNIP2 TNFAIP3 interacting protein 2 0.658
SOX10 SRY (sex determining region Y)-box 10 0.649
SNTA1 syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) 0.602
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.591
CHUK conserved helix-loop-helix ubiquitous kinase 0.574
JUNB jun B proto-oncogene 0.467
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 0.432
FOS FBJ murine osteosarcoma viral oncogene homolog 0.386
IL4R interleukin 4 receptor 0.378
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.298
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.293
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.267
RARA retinoic acid receptor, alpha 0.224
ATF3 activating transcription factor 3 0.220
SPTAN1 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) 0.187
NLRC4 NLR family, CARD domain containing 4 0.173
STAP2 signal transducing adaptor family member 2 0.151
RXRA retinoid X receptor, alpha 0.139
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.128
NKX2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.124
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.120
CPNE6 copine VI (neuronal) 0.109
TLR2 toll-like receptor 2 0.106
MAP3K14 mitogen-activated protein kinase kinase kinase 14 0.074
DUSP1 dual specificity phosphatase 1 0.070
RIPK2 receptor-interacting serine-threonine kinase 2 0.068
INSR insulin receptor 0.067
JUN jun proto-oncogene 0.067
IL2RB interleukin 2 receptor, beta 0.064
IER2 immediate early response 2 0.060
PKN1 protein kinase N1 0.059
NCOA1 nuclear receptor coactivator 1 0.057
JAK1 Janus kinase 1 0.056
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.055
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.054
TLR4 toll-like receptor 4 0.053
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.051
C16orf53 chromosome 16 open reading frame 53 0.050
MAPK8 mitogen-activated protein kinase 8 0.048
MAVS mitochondrial antiviral signaling protein 0.046
ZFP36 zinc finger protein 36, C3H type, homolog (mouse) 0.043
RAI1 retinoic acid induced 1 0.041
ITGB1BP1 integrin beta 1 binding protein 1 0.041
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 0.041
KCNQ1 potassium voltage-gated channel, KQT-like subfamily, member 1 0.041
NMI N-myc (and STAT) interactor 0.040
TP53BP1 tumor protein p53 binding protein 1 0.039
EVL Enah/Vasp-like 0.038
SOCS3 suppressor of cytokine signaling 3 0.036
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.036
RBBP5 retinoblastoma binding protein 5 0.035
TMEM173 transmembrane protein 173 0.035
JUND jun D proto-oncogene 0.035
EPB49 erythrocyte membrane protein band 4.9 (dematin) 0.034
TBX5 T-box 5 0.034
PPP1R15A protein phosphatase 1, regulatory (inhibitor) subunit 15A 0.034
ELF4 E74-like factor 4 (ets domain transcription factor) 0.034
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.034
FKBP5 FK506 binding protein 5 0.033
SOX1 SRY (sex determining region Y)-box 1 0.032
IRAK2 interleukin-1 receptor-associated kinase 2 0.032
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.031
TCF4 transcription factor 4 0.031
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 0.031
CSNK1A1 casein kinase 1, alpha 1 0.031
BIRC3 baculoviral IAP repeat containing 3 0.030
BATF2 basic leucine zipper transcription factor, ATF-like 2 0.030
PAX3 paired box 3 0.029
EGR1 early growth response 1 0.029
PRUNE prune homolog (Drosophila) 0.029
ATXN3 ataxin 3 0.029
IL4 interleukin 4 0.028
IRF1 interferon regulatory factor 1 0.028
KDM6B lysine (K)-specific demethylase 6B 0.028
MEN1 multiple endocrine neoplasia I 0.028
EP300 E1A binding protein p300 0.028
PYCARD PYD and CARD domain containing 0.027
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 0.027
DUSP9 dual specificity phosphatase 9 0.027
ZC3H12A zinc finger CCCH-type containing 12A 0.027
CARD16 caspase recruitment domain family, member 16 0.026
FLOT1 flotillin 1 0.026
BTRC beta-transducin repeat containing 0.025
BEND5 BEN domain containing 5 0.025
TLR1 toll-like receptor 1 0.024
BTBD2 BTB (POZ) domain containing 2 0.024
MVP major vault protein 0.024
SOX21 SRY (sex determining region Y)-box 21 0.024
USP20 ubiquitin specific peptidase 20 0.024
NCOA3 nuclear receptor coactivator 3 0.024
UBXN7 UBX domain protein 7 0.024
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism