IMP

Process View

Drosophila melanogaster

12 genes annotated in fly

retinal ganglion cell axon guidance

The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "retinal ganglion cell axon guidance"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "retinal ganglion cell axon guidance" (in gray)

Name	Description	Probability	Func Analog Organism
ttv	tout-velu	0.998
robo	roundabout	0.997	Zebrafish Mouse
dock	dreadlocks	0.996
fra	frazzled	0.988
robo3	CG5423 gene product from transcript CG5423-RA	0.982	Zebrafish Mouse
trio	CG18214 gene product from transcript CG18214-RA	0.982
NetB	Netrin-B	0.974
wg	wingless	0.972	Fly
dsh	dishevelled	0.970
Sema-1a	CG18405 gene product from transcript CG18405-RD	0.967
CadN	Cadherin-N	0.956
babo	baboon	0.950
Ptp69D	Protein tyrosine phosphatase 69D	0.937
otk	off-track	0.923
lea	leak	0.917	Zebrafish Mouse
Ext2	CG8433 gene product from transcript CG8433-RA	0.904	Zebrafish
Mad	Mothers against dpp	0.902	Fly
comm	commissureless	0.898
ci	cubitus interruptus	0.890	Zebrafish
tutl	turtle	0.889
msn	misshapen	0.862
N	Notch	0.847
tgo	tango	0.837
Sema-2a	CG4700 gene product from transcript CG4700-RC	0.806	Zebrafish
stan	starry night	0.783
unc-5	CG8166 gene product from transcript CG8166-RA	0.768
Eph	Eph receptor tyrosine kinase	0.763	Mouse
en	engrailed	0.756
botv	brother of tout-velu	0.714	Zebrafish
Dscam	Down syndrome cell adhesion molecule	0.705
hh	hedgehog	0.690
hth	homothorax	0.670
Caps	Calcium activated protein for secretion	0.663
sbb	scribbler	0.647
nct	nicastrin	0.625
Liprin-alpha	CG11199 gene product from transcript CG11199-RB	0.617
sli	slit	0.608	Human Mouse
ena	enabled	0.581
LIMK1	LIM-kinase1	0.551
smo	smoothened	0.531	Zebrafish
put	punt	0.520
gcm	glial cells missing	0.508
arr	arrow	0.465
Pak	PAK-kinase	0.459
mam	mastermind	0.454
nvy	nervy	0.449
jing	CG9397 gene product from transcript CG9397-RI	0.439
plexA	plexin A	0.437
Fak56D	Focal Adhesion Kinase	0.429
tok	tolkin	0.395
spen	split ends	0.393
ems	empty spiracles	0.377
kn	knot	0.365
disp	dispatched	0.363	Zebrafish
Bre1	CG10542 gene product from transcript CG10542-RA	0.343
Sdc	Syndecan	0.338
Wnt4	Wnt oncogene analog 4	0.295
Wnt5	Wnt oncogene analog 5	0.284
neur	neuralized	0.281
Ser	Serrate	0.267
SoxN	SoxNeuro	0.247
gro	groucho	0.228
Smox	Smad on X	0.227	Fly
milt	milton	0.210
tup	tailup	0.202	Mouse
Fas2	Fasciclin 2	0.191
ey	eyeless	0.176
Lim3	CG10699 gene product from transcript CG10699-RB	0.167
ptc	patched	0.161	Zebrafish
rap	retina aberrant in pattern	0.157
wls	wntless	0.145
CaMKII	Calcium/calmodulin-dependent protein kinase II	0.138
eya	eyes absent	0.134
dally	division abnormally delayed	0.132
grn	grain	0.119
beat-Ia	beaten path Ia	0.113
plexB	plexin B	0.109
Trim9	CG31721 gene product from transcript CG31721-RB	0.109
hkb	huckebein	0.108
Ephrin	CG1862 gene product from transcript CG1862-RA	0.108
pod1	CG4532 gene product from transcript CG4532-RF	0.107
fz2	frizzled 2	0.106
Nrt	Neurotactin	0.106
pros	prospero	0.106
rok	Rho-kinase	0.099
drl	derailed	0.098
Egfr	Epidermal growth factor receptor	0.095
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.095
endoA	endophilin A	0.093
Abl	Abl tyrosine kinase	0.092
stai	stathmin	0.089
repo	reversed polarity	0.087
dlp	dally-like	0.087
LanA	Laminin A	0.086
cos	costa	0.085
Notum	CG13076 gene product from transcript CG13076-RB	0.085
argos	CG4531 gene product from transcript CG4531-RA	0.081
HGTX	CG13475 gene product from transcript CG13475-RB	0.079
lola	longitudinals lacking	0.079
gogo	golden goal	0.078
Ten-m	Tenascin major	0.073	Zebrafish
zfh1	Zn finger homeodomain 1	0.071
sec15	CG7034 gene product from transcript CG7034-RA	0.067
nerfin-1	nervous fingers 1	0.067
foi	fear-of-intimacy	0.067
synj	synaptojanin	0.067
fng	fringe	0.066
vvl	ventral veins lacking	0.066
Tl	Toll	0.066
Fas3	Fasciclin 3	0.063
CG12424	CG12424 gene product from transcript CG12424-RC	0.062
pcx	pecanex	0.060
Rac1	CG2248 gene product from transcript CG2248-RA	0.059
NetA	Netrin-A	0.059
RhoGAPp190	CG32555 gene product from transcript CG32555-RB	0.058
Mical	Molecule interacting with CasL	0.058
kuz	kuzbanian	0.055
rictor	rapamycin-insensitive companion of Tor	0.055
Hem	HEM-protein	0.054
sd	scalloped	0.051
side	sidestep	0.050
numb	CG3779 gene product from transcript CG3779-RB	0.049
Ca-alpha1D	Ca[2+]-channel protein alpha[[1]] subunit D	0.048
Dcr-1	Dicer-1	0.045
Fmr1	CG6203 gene product from transcript CG6203-RC	0.041
Su(H)	Suppressor of Hairless	0.040
sgg	shaggy	0.040
dpp	decapentaplegic	0.040
ds	dachsous	0.040
lbl	ladybird late	0.039
slmb	supernumerary limbs	0.039
wb	wing blister	0.039
elav	embryonic lethal abnormal vision	0.036
CG9063	CG9063 gene product from transcript CG9063-RA	0.036
RhoGAP93B	CG3421 gene product from transcript CG3421-RA	0.035
ex	expanded	0.035
retn	retained	0.034
Dad	Daughters against dpp	0.034
brk	brinker	0.034
shot	short stop	0.033
shn	schnurri	0.032
Mcr	Macroglobulin complement-related	0.031
AGO1	Argonaute-1	0.031
CG31352	CG31352 gene product from transcript CG31352-RA	0.031
RhoGAP71E	CG32149 gene product from transcript CG32149-RD	0.031
por	porcupine	0.031
fu	fused	0.030
erm	earmuff	0.030
futsch	CG34387 gene product from transcript CG34387-RC	0.030
Pc	Polycomb	0.030
Kr	Kruppel	0.029
Tollo	CG6890 gene product from transcript CG6890-RA	0.029
jeb	jelly belly	0.029
hts	hu li tai shao	0.028
hyd	hyperplastic discs	0.028
tkv	thickveins	0.027	Mouse
svp	seven up	0.026
Gug	Grunge	0.026
Snoo	Sno oncogene	0.025
Gyc76C	Guanylyl cyclase at 76C	0.025
Hr51	Hormone receptor 51	0.025
Stat92E	Signal-transducer and activator of transcription protein at 92E	0.025
Nrg	Neuroglian	0.022
InR	Insulin-like receptor	0.021
G-oalpha47A	G protein oalpha 47A	0.021
tll	tailless	0.021
Su(z)12	CG8013 gene product from transcript CG8013-RA	0.021
eve	even skipped	0.021
sim	single-minded	0.020
gbb	glass bottom boat	0.020
cnk	connector enhancer of ksr	0.020
tey	teyrha-meyrha	0.020
CkIalpha	Casein kinase Ialpha	0.019
Vap-33-1	CG5014 gene product from transcript CG5014-RB	0.019
sqz	squeeze	0.019
in	inturned	0.018
hipk	homeodomain interacting protein kinase	0.018
Alk	CG8250 gene product from transcript CG8250-RA	0.018
RhoGAP100F	CG1976 gene product from transcript CG1976-RB	0.018
l(2)k16918	lethal (2) k16918	0.018
btl	breathless	0.018
sgl	sugarless	0.018
fj	four-jointed	0.018
Wnk	CG7177 gene product from transcript CG7177-RA	0.017
chinmo	Chronologically inappropriate morphogenesis	0.017
tsh	teashirt	0.017
Sulf1	Sulfated	0.017
bsk	basket	0.017
Nrx-IV	Neurexin IV	0.017
Klp64D	Kinesin-like protein at 64D	0.016
spas	spastin	0.016
Wnt2	Wnt oncogene analog 2	0.016	Fly
inv	invected	0.016
mira	miranda	0.016
gig	gigas	0.016
Ptp52F	CG18243 gene product from transcript CG18243-RB	0.016
CG31048	CG31048 gene product from transcript CG31048-RB	0.016
Mkk4	MAP kinase kinase 4	0.016
salm	spalt major	0.015
exex	extra-extra	0.015
not	non-stop	0.015
seq	sequoia	0.015
Sara	Smad anchor for receptor activation	0.015
Sema-1b	CG6446 gene product from transcript CG6446-RA	0.014
ssh	slingshot	0.014
nkd	naked cuticle	0.014
rib	ribbon	0.014
CG12029	CG12029 gene product from transcript CG12029-RB	0.014
run	runt	0.014
Pten	CG5671 gene product from transcript CG5671-RB	0.013
bsh	brain-specific homeobox	0.013
trn	tartan	0.013
frtz	fritz	0.013
mid	midline	0.012
sll	slalom	0.012	Zebrafish
dac	dachshund	0.012
cg	combgap	0.012
nub	nubbin	0.012
htl	heartless	0.012
LanB1	CG7123 gene product from transcript CG7123-RA	0.012
lbe	ladybird early	0.012
Ptp10D	Protein tyrosine phosphatase 10D	0.012
daw	dawdle	0.012
kis	kismet	0.012
rho	rhomboid	0.012
cv-c	crossveinless c	0.012
heph	hephaestus	0.011
sens	senseless	0.011
bif	bifocal	0.011
slp1	sloppy paired 1	0.011
CG6490	CG6490 gene product from transcript CG6490-RB	0.011
alpha-Adaptin	CG4260 gene product from transcript CG4260-RA	0.011
oys	oysgedart	0.011
skd	skuld	0.011
CG14869	CG14869 gene product from transcript CG14869-RB	0.011
ab	abrupt	0.011
bnl	branchless	0.011
ara	araucan	0.011
Patr-1	Protein associated with topo II related - 1	0.010
CG6522	CG6522 gene product from transcript CG6522-RA	0.010
beta-Spec	beta Spectrin	0.010
Akt1	CG4006 gene product from transcript CG4006-RA	0.010
Sra-1	specifically Rac1-associated protein 1	0.010	Zebrafish
gsb	gooseberry	0.010
Actbeta	Activin-beta	0.010