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Process View

Drosophila melanogaster

28 genes annotated in fly

synaptic vesicle recycling

The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "synaptic vesicle recycling"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "synaptic vesicle recycling" (in gray)

Name	Description	Probability	Func Analog Organism
lap	like-AP180	0.999
hiw	highwire	0.995
stnA	stoned A	0.978
PP2A-B'	CG7913 gene product from transcript CG7913-RK	0.978
Syt1	Synaptotagmin 1	0.978
unc-104	CG8566 gene product from transcript CG8566-RB	0.978
GluRIIA	Glutamate receptor IIA	0.976
Snap25	Synapse protein 25	0.974
endoA	endophilin A	0.973
wit	wishful thinking	0.969
comt	comatose	0.956
stj	straightjacket	0.954
brp	bruchpilot	0.952
nwk	nervous wreck	0.942
Dab	Disabled	0.927
Nrx-1	Neurexin 1	0.925
Dap160	Dynamin associated protein 160	0.920
cpx	complexin	0.871
CaMKII	Calcium/calmodulin-dependent protein kinase II	0.716
cac	cacophony	0.713
rtGEF	rho-type guanine exchange factor	0.705
Smg1	CG32743 gene product from transcript CG32743-RA	0.692
stnB	stoned B	0.675
Syx1A	Syntaxin 1A	0.653
Rab5	Rab-protein 5	0.616
Ank2	Ankyrin 2	0.595
TBPH	CG10327 gene product from transcript CG10327-RC	0.574
dys	dysfusion	0.552
sgl	sugarless	0.536
Arp66B	Actin-related protein 66B	0.522
neuroligin	CG13772 gene product from transcript CG13772-RA	0.519	Mouse Rat
synj	synaptojanin	0.517
Caki	Calcium/calmodulin-dependent protein kinase	0.508
pAbp	polyA-binding protein	0.457
Snap	Soluble NSF attachment protein	0.450
mle	maleless	0.434
beta-Spec	beta Spectrin	0.433
n-syb	n-synaptobrevin	0.398
Mob4	CG3403 gene product from transcript CG3403-RA	0.375
Eps-15	Epidermal growth factor receptor pathway substrate clone 15	0.354
sei	seizure	0.345
Khc	Kinesin heavy chain	0.343
Atpalpha	Na pump alpha subunit	0.342
Liprin-alpha	CG11199 gene product from transcript CG11199-RB	0.326
Fak56D	Focal Adhesion Kinase	0.319
WASp	CG1520 gene product from transcript CG1520-RA	0.314
TER94	CG2331 gene product from transcript CG2331-RA	0.306
alpha-Spec	alpha Spectrin	0.296
Syt4	Synaptotagmin 4	0.274
wnd	wallenda	0.273
Csp	Cysteine string protein	0.272
syd	sunday driver	0.263
rut	rutabaga	0.252
Imp	IGF-II mRNA-binding protein	0.246
hk	hook	0.241
HDAC6	CG6170 gene product from transcript CG6170-RA	0.236
spict	spichthyin	0.231
Alk	CG8250 gene product from transcript CG8250-RA	0.225
Adar	Adenosine deaminase acting on RNA	0.218
Gad1	Glutamic acid decarboxylase 1	0.205
VGlut	Vesicular glutamate transporter	0.199
Frq1	Frequenin 1	0.187
Vmat	Vesicular monoamine transporter	0.185
milt	milton	0.179
dlp	dally-like	0.177
unc-13	CG2999 gene product from transcript CG2999-RA	0.160	Mouse
CG9339	CG9339 gene product from transcript CG9339-RG	0.155
alpha-Adaptin	CG4260 gene product from transcript CG4260-RA	0.151
CG12753	CG12753 gene product from transcript CG12753-RB	0.151
CG12187	CG12187 gene product from transcript CG12187-RA	0.138
heph	hephaestus	0.115
stmA	stambha A	0.113
dlg1	discs large 1	0.108	Mouse
CrebB-17A	Cyclic-AMP response element binding protein B at 17A	0.105
CG31146	CG31146 gene product from transcript CG31146-RD	0.101	Rat
jeb	jelly belly	0.101
RhoGAP92B	CG4755 gene product from transcript CG4755-RA	0.099
kcc	kazachoc	0.096
faf	fat facets	0.086
CDase	Ceramidase	0.082
SAK	Sak kinase	0.081
Aplip1	APP-like protein interacting protein 1	0.080
Nrg	Neuroglian	0.071
dnc	dunce	0.064
Lrrk	Leucine-rich repeat kinase	0.063
slo	slowpoke	0.063
simj	simjang	0.062
mnb	minibrain	0.062
Rae1	CG9862 gene product from transcript CG9862-RA	0.061
Oli	Olig family	0.057
GluRIIB	Glutamate receptor IIB	0.057
l(2)k16918	lethal (2) k16918	0.056
synaptogyrin	CG10808 gene product from transcript CG10808-RA	0.055
CG43073	CG43073 gene product from transcript CG43073-RF	0.052
ttv	tout-velu	0.049
Vha100-1	CG1709 gene product from transcript CG1709-RF	0.049
ST6Gal	Sialyltransferase	0.049
Nsf2	NEM-sensitive fusion protein 2	0.047
VAChT	CG32848 gene product from transcript CG32848-RA	0.046
KaiRIA	CG18039 gene product from transcript CG18039-RA	0.045
mGluRA	metabotropic glutamate receptor	0.044
sfl	sulfateless	0.044
Ext2	CG8433 gene product from transcript CG8433-RA	0.044	Fly
G-oalpha47A	G protein oalpha 47A	0.043
hig	hikaru genki	0.041
yrt	yurt	0.041
Ggamma1	G protein gamma 1	0.041
sif	still life	0.041
Nf1	Neurofibromin 1	0.040
cdm	cadmus	0.039
Sec61alpha	CG9539 gene product from transcript CG9539-RA	0.039
Chc	Clathrin heavy chain	0.038
O-fut1	O-fucosyltransferase 1	0.038
tweek	CG42555 gene product from transcript CG42555-RD	0.037
lat	latheo	0.037
par-1	CG8201 gene product from transcript CG8201-RA	0.036
Miro	Mitochondrial Rho	0.036
Dsk	Drosulfakinin	0.036
Pros54	Proteasome 54kD subunit	0.035
nudE	CG8104 gene product from transcript CG8104-RB	0.035
Sop2	Suppressor of profilin 2	0.034
Syx18	Syntaxin 18	0.034
disp	dispatched	0.032
Mical	Molecule interacting with CasL	0.032
wol	wollknaeuel	0.031
Sbf	SET domain binding factor	0.031
Rop	Ras opposite	0.031	Mouse
Arp14D	Actin-related protein 14D	0.027
Vsx2	CG33980 gene product from transcript CG33980-RA	0.026
CG34360	CG34360 gene product from transcript CG34360-RA	0.026
GluRIIE	Glutamate receptor IIE	0.025
Cdk5alpha	Cdk5 activator-like protein	0.024
Rab6	Rab-protein 6	0.024
kdn	knockdown	0.024
Cortactin	CG3637 gene product from transcript CG3637-RA	0.024
CG10260	CG10260 gene product from transcript CG10260-RB	0.024
gammaCop	gamma-coatomer protein	0.024
l(1)G0148	lethal (1) G0148	0.024
CG9139	CG9139 gene product from transcript CG9139-RA	0.023
spas	spastin	0.023
CanA-14F	Calcineurin A at 14F	0.022
Pgk	Phosphoglycerate kinase	0.022
CCKLR-17D1	CCK-like receptor at 17D1	0.022
Letm1	CG4589 gene product from transcript CG4589-RB	0.021
Bsg	Basigin	0.021
Asator	CG11533 gene product from transcript CG11533-RF	0.020
bdg	bedraggled	0.020
stai	stathmin	0.020
fusl	fuseless	0.020
Rfx	CG6312 gene product from transcript CG6312-RA	0.020
GluRIIC	Glutamate receptor IIC	0.020
CG9063	CG9063 gene product from transcript CG9063-RA	0.019
CkIalpha	Casein kinase Ialpha	0.019
poe	purity of essence	0.019
Khc-73	Kinesin-73	0.018	Fly
wls	wntless	0.018
Takr99D	Tachykinin-like receptor at 99D	0.018
Med	Medea	0.018
Frq2	Frequenin 2	0.018
trpml	transient receptor potential mucolipin	0.018
capt	capulet	0.017
Hip14	Huntingtin-interacting protein 14	0.017
NKAIN	Na,K-ATPase Interacting	0.017
slmb	supernumerary limbs	0.017
Rab3	Rab-protein 3	0.017	Mouse
Pp2A-29B	Protein phosphatase 2A at 29B	0.017
kkv	krotzkopf verkehrt	0.016
norpA	no receptor potential A	0.016
4EHP	CG33100 gene product from transcript CG33100-RA	0.015
Amph	Amphiphysin	0.015	Mouse
beta4GalNAcTA	CG8536 gene product from transcript CG8536-RA	0.015
Dhc64C	Dynein heavy chain 64C	0.015
AdoR	Adenosine receptor	0.014
sec5	CG8843 gene product from transcript CG8843-RA	0.014
TyrR	Tyramine receptor	0.014
Trc8	CG2304 gene product from transcript CG2304-RB	0.014
nmo	nemo	0.014
CG10426	CG10426 gene product from transcript CG10426-RA	0.014
pigeon	CG10739 gene product from transcript CG10739-RB	0.014
nompC	no mechanoreceptor potential C	0.014
Gug	Grunge	0.014
Rpn6	Proteasome p44.5 subunit	0.014
mr	morula	0.014
CG17184	CG17184 gene product from transcript CG17184-RB	0.014
katanin-60	katanin 60	0.014
Tango1	Transport and Golgi organization 1	0.014
rev7	CG2948 gene product from transcript CG2948-RA	0.014
Cyp303a1	CG4163 gene product from transcript CG4163-RA	0.013
Cip4	CG15015 gene product from transcript CG15015-RA	0.013
Galpha49B	G protein alpha49B	0.013
scb	scab	0.013
Mob2	CG11711 gene product from transcript CG11711-RC	0.013
Ppat-Dpck	Bifunctional Phosphopantetheine adenylyltransferase - Dephospho-CoA kinase	0.013
CG11857	CG11857 gene product from transcript CG11857-RA	0.013
plu	plutonium	0.013
t	tan	0.012
bnl	branchless	0.012
rnh1	ribonuclease H1	0.012
CG6359	CG6359 gene product from transcript CG6359-RA	0.012
lkb1	CG9374 gene product from transcript CG9374-RJ	0.012
cpo	couch potato	0.012
Shaw	Shaker cognate w	0.012
SRPK	CG8174 gene product from transcript CG8174-RA	0.012
Ca-P60A	Calcium ATPase at 60A	0.012
jagn	jagunal	0.011
Rbsn-5	Rabenosyn-5	0.011
CG12026	CG12026 gene product from transcript CG12026-RB	0.011
mol	moladietz	0.011
kermit	CG11546 gene product from transcript CG11546-RB	0.011
Gprk1	G protein-coupled receptor kinase 1	0.011
CG4164	CG4164 gene product from transcript CG4164-RA	0.011
CG6116	CG6116 gene product from transcript CG6116-RA	0.011
spin	spinster	0.011
Ppt1	Palmitoyl-protein thioesterase 1	0.011
Drp1	Dynamin related protein 1	0.011
CG9384	CG9384 gene product from transcript CG9384-RA	0.011
SNF4Agamma	SNF4/AMP-activated protein kinase gamma subunit	0.011
Syx5	Syntaxin 5	0.011
Kap3	Kinesin associated protein 3	0.011
CG2224	CG2224 gene product from transcript CG2224-RA	0.011
Ace	Acetylcholine esterase	0.010
tefu	telomere fusion	0.010
Mcm10	Sensitized chromosome inheritance modifier 19	0.010
Syx13	Syntaxin 13	0.010
daw	dawdle	0.010
flfl	falafel	0.010
vkg	viking	0.010