IMP

Process View

Mus musculus

12 genes annotated in mouse

positive regulation of neutrophil chemotaxis

Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of neutrophil chemotaxis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of neutrophil chemotaxis" (in gray)

Name	Description	Probability	Func Analog Organism
Ccl3	chemokine (C-C motif) ligand 3	0.988	Mouse
Selp	selectin, platelet	0.974
Ccl2	chemokine (C-C motif) ligand 2	0.969
Ccr2	chemokine (C-C motif) receptor 2	0.967	Mouse
Ccr1	chemokine (C-C motif) receptor 1	0.959	Mouse
Itgax	integrin alpha X	0.906
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.836
Ccl4	chemokine (C-C motif) ligand 4	0.745	Mouse
C3ar1	complement component 3a receptor 1	0.732
Il1b	interleukin 1 beta	0.732
Ccr5	chemokine (C-C motif) receptor 5	0.712	Mouse
Ccl8	chemokine (C-C motif) ligand 8	0.703
Fcgr1	Fc receptor, IgG, high affinity I	0.552
Rac1	RAS-related C3 botulinum substrate 1	0.538
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.499
Batf	basic leucine zipper transcription factor, ATF-like	0.492
C5ar1	complement component 5a receptor 1	0.475
Slfn1	schlafen 1	0.473
AF251705	cDNA sequence AF251705	0.473
Il1rn	interleukin 1 receptor antagonist	0.437
H2-Eb1	histocompatibility 2, class II antigen E beta	0.340
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.337
Cybb	cytochrome b-245, beta polypeptide	0.322
Cxcl2	chemokine (C-X-C motif) ligand 2	0.306
Irg1	immunoresponsive gene 1	0.303
Rac2	RAS-related C3 botulinum substrate 2	0.297
Mmp8	matrix metallopeptidase 8	0.295
Ccl9	chemokine (C-C motif) ligand 9	0.280	Mouse
Msr1	macrophage scavenger receptor 1	0.273
Pak1	p21 protein (Cdc42/Rac)-activated kinase 1	0.272
Clec4e	C-type lectin domain family 4, member e	0.271
Cxcr2	chemokine (C-X-C motif) receptor 2	0.266	Mouse Rat
Itgal	integrin alpha L	0.256
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.250
Sele	selectin, endothelial cell	0.248
Gm14548	predicted gene 14548	0.246
Has1	hyaluronan synthase1	0.240
Mmp12	matrix metallopeptidase 12	0.234
Clec4d	C-type lectin domain family 4, member d	0.231
Hp	haptoglobin	0.223
Slfn4	schlafen 4	0.212
S100a8	S100 calcium binding protein A8 (calgranulin A)	0.209
Mmp3	matrix metallopeptidase 3	0.206
Fpr1	formyl peptide receptor 1	0.201	Mouse
Ear2	eosinophil-associated, ribonuclease A family, member 2	0.197
S100a9	S100 calcium binding protein A9 (calgranulin B)	0.196
Bdkrb1	bradykinin receptor, beta 1	0.185
Cd14	CD14 antigen	0.184
Ch25h	cholesterol 25-hydroxylase	0.184
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.183
Cx3cr1	chemokine (C-X3-C) receptor 1	0.179	Mouse
Chi3l3	chitinase 3-like 3	0.179
Ctsw	cathepsin W	0.177
Cd7	CD7 antigen	0.175
Gzmb	granzyme B	0.172
Itgam	integrin alpha M	0.162
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.159
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.154
Ifitm6	interferon induced transmembrane protein 6	0.151
Ccl6	chemokine (C-C motif) ligand 6	0.150	Mouse
Fpr3	formyl peptide receptor 3	0.149	Mouse
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.145
Saa3	serum amyloid A 3	0.139
Gzma	granzyme A	0.137
Il1a	interleukin 1 alpha	0.135
9430031J16Rik	RIKEN cDNA 9430031J16 gene	0.135
Icam1	intercellular adhesion molecule 1	0.131
Cd96	CD96 antigen	0.131
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.130
Folr2	folate receptor 2 (fetal)	0.130
Il7r	interleukin 7 receptor	0.130
Selplg	selectin, platelet (p-selectin) ligand	0.129
Sell	selectin, lymphocyte	0.126	Rat
Fpr2	formyl peptide receptor 2	0.125	Mouse
Ubd	ubiquitin D	0.124
Itgb2	integrin beta 2	0.114
Cd44	CD44 antigen	0.109
Cd3e	CD3 antigen, epsilon polypeptide	0.109
Ccl12	chemokine (C-C motif) ligand 12	0.106	Mouse
H2-DMa	histocompatibility 2, class II, locus DMa	0.104
Il18rap	interleukin 18 receptor accessory protein	0.101
Tlr7	toll-like receptor 7	0.101
Jak3	Janus kinase 3	0.101
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.098
Cxcl13	chemokine (C-X-C motif) ligand 13	0.091
Slpi	secretory leukocyte peptidase inhibitor	0.090
Ccl7	chemokine (C-C motif) ligand 7	0.085	Mouse
Lcn2	lipocalin 2	0.085
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.084
Cxcl1	chemokine (C-X-C motif) ligand 1	0.084
Gpr132	G protein-coupled receptor 132	0.082
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.081
Sh2d2a	SH2 domain protein 2A	0.081
Ccl17	chemokine (C-C motif) ligand 17	0.081	Mouse
Ifng	interferon gamma	0.080
Myo1f	myosin IF	0.080
Cd180	CD180 antigen	0.079
Sfpi1	SFFV proviral integration 1	0.079
Il2rb	interleukin 2 receptor, beta chain	0.079
Xcr1	chemokine (C motif) receptor 1	0.076	Mouse
H2-M9	histocompatibility 2, M region locus 9	0.072
Il18r1	interleukin 18 receptor 1	0.070
S1pr4	sphingosine-1-phosphate receptor 4	0.067
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.067
Ccl22	chemokine (C-C motif) ligand 22	0.064
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.063
Tbxas1	thromboxane A synthase 1, platelet	0.063
Il12rb2	interleukin 12 receptor, beta 2	0.062
Asprv1	aspartic peptidase, retroviral-like 1	0.059
Acvr1	activin A receptor, type 1	0.057
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.054
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.053
Chi3l1	chitinase 3-like 1	0.052
Expi	extracellular proteinase inhibitor	0.052
Tubb4	tubulin, beta 4	0.052
F10	coagulation factor X	0.052
Dok2	docking protein 2	0.049
1100001G20Rik	RIKEN cDNA 1100001G20 gene	0.049
Arhgdib	Rho, GDP dissociation inhibitor (GDI) beta	0.048
Il10ra	interleukin 10 receptor, alpha	0.047
Mrpl3	mitochondrial ribosomal protein L3	0.044
Ly9	lymphocyte antigen 9	0.043
Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.043
Rhoa	ras homolog gene family, member A	0.043
Il12b	interleukin 12b	0.043
Timm10	translocase of inner mitochondrial membrane 10 homolog (yeast)	0.041
C1qc	complement component 1, q subcomponent, C chain	0.041
Cxcr3	chemokine (C-X-C motif) receptor 3	0.041	Mouse
Osmr	oncostatin M receptor	0.040
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.040
Clec4a2	C-type lectin domain family 4, member a2	0.039
Plxnd1	plexin D1	0.039
Arhgap1	Rho GTPase activating protein 1	0.039
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.036
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.034
Ifngr1	interferon gamma receptor 1	0.034
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.033	Mouse
Msn	moesin	0.033
Ctnnb1	catenin (cadherin associated protein), beta 1	0.032
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.032
Ncr1	natural cytotoxicity triggering receptor 1	0.031
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.030
Rasal3	RAS protein activator like 3	0.030
Bcl3	B-cell leukemia/lymphoma 3	0.030
Mx2	myxovirus (influenza virus) resistance 2	0.030
Cxcl5	chemokine (C-X-C motif) ligand 5	0.029
Cd3d	CD3 antigen, delta polypeptide	0.029
Csf1	colony stimulating factor 1 (macrophage)	0.029
Ltb	lymphotoxin B	0.029
Ngp	neutrophilic granule protein	0.028
Niacr1	niacin receptor 1	0.028
Ccr1l1	chemokine (C-C motif) receptor 1-like 1	0.028	Mouse
Prkar1b	protein kinase, cAMP dependent regulatory, type I beta	0.028
Tlr2	toll-like receptor 2	0.028
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.027
Retnlb	resistin like beta	0.027
Mmp9	matrix metallopeptidase 9	0.027
Clec7a	C-type lectin domain family 7, member a	0.027
Gfpt2	glutamine fructose-6-phosphate transaminase 2	0.026
Wdr1	WD repeat domain 1	0.026
Arpc4	actin related protein 2/3 complex, subunit 4	0.026
Xcl1	chemokine (C motif) ligand 1	0.026
Atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	0.026
Cd300ld	CD300 molecule-like family member d	0.025
Plau	plasminogen activator, urokinase	0.025
LOC100503923	hypothetical protein LOC100503923	0.024
Cd209b	CD209b antigen	0.024
Lsp1	lymphocyte specific 1	0.024
Il1f9	interleukin 1 family, member 9	0.024
Pdcd1	programmed cell death 1	0.024
Acvrl1	activin A receptor, type II-like 1	0.024
Cd40	CD40 antigen	0.024
Siglece	sialic acid binding Ig-like lectin E	0.024
Cd8a	CD8 antigen, alpha chain	0.023
Ccl5	chemokine (C-C motif) ligand 5	0.023	Mouse
Cd33	CD33 antigen	0.023
Pdcd1lg2	programmed cell death 1 ligand 2	0.023
Il1rl1	interleukin 1 receptor-like 1	0.023
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.023
Cxcl9	chemokine (C-X-C motif) ligand 9	0.023
Prdm1	PR domain containing 1, with ZNF domain	0.022
Ly6c2	lymphocyte antigen 6 complex, locus C2	0.022
Aoah	acyloxyacyl hydrolase	0.022
Cd37	CD37 antigen	0.022
Ptgir	prostaglandin I receptor (IP)	0.021
Stat5a	signal transducer and activator of transcription 5A	0.021
Opn1mw	opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan)	0.021
Mc2r	melanocortin 2 receptor	0.020
Cytip	cytohesin 1 interacting protein	0.020
Krtap12-1	keratin associated protein 12-1	0.020
Oxt	oxytocin	0.020
Cd86	CD86 antigen	0.020
Ltf	lactotransferrin	0.020
Serpinb2	serine (or cysteine) peptidase inhibitor, clade B, member 2	0.020
Steap4	STEAP family member 4	0.020
Ciita	class II transactivator	0.020
Has3	hyaluronan synthase 3	0.019
Vasp	vasodilator-stimulated phosphoprotein	0.019
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.019
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.019
Hdc	histidine decarboxylase	0.019
Lox	lysyl oxidase	0.019
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.019
Timp1	tissue inhibitor of metalloproteinase 1	0.019
Wisp2	WNT1 inducible signaling pathway protein 2	0.019
Il4ra	interleukin 4 receptor, alpha	0.019
Nckap1l	NCK associated protein 1 like	0.019
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.019
Foxi3	forkhead box I3	0.018
Prg3	proteoglycan 3	0.018
Efnb2	ephrin B2	0.018
Fcer2a	Fc receptor, IgE, low affinity II, alpha polypeptide	0.018
Gzmk	granzyme K	0.018
Efna1	ephrin A1	0.018
Il12a	interleukin 12a	0.018
Apod	apolipoprotein D	0.018
Stat5b	signal transducer and activator of transcription 5B	0.018
Ednrb	endothelin receptor type B	0.018
Gpr97	G protein-coupled receptor 97	0.018
Ttc7	tetratricopeptide repeat domain 7	0.018
Il20	interleukin 20	0.017
Slfn2	schlafen 2	0.017
Sirpa	signal-regulatory protein alpha	0.017
Cd52	CD52 antigen	0.017
Olfr70	olfactory receptor 70	0.016
Entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.016
Laptm5	lysosomal-associated protein transmembrane 5	0.016
Krtap3-1	keratin associated protein 3-1	0.016
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.016
Tnfrsf18	tumor necrosis factor receptor superfamily, member 18	0.016
Meox1	mesenchyme homeobox 1	0.016
Ncf4	neutrophil cytosolic factor 4	0.016
Tbx21	T-box 21	0.016
Fmnl1	formin-like 1	0.016
Cxcl14	chemokine (C-X-C motif) ligand 14	0.015
Cd2	CD2 antigen	0.015
Cst7	cystatin F (leukocystatin)	0.015
Opn1sw	opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)	0.015
Cd6	CD6 antigen	0.015
Sod3	superoxide dismutase 3, extracellular	0.015
Rarb	retinoic acid receptor, beta	0.015
Pecam1	platelet/endothelial cell adhesion molecule 1	0.015
Adam8	a disintegrin and metallopeptidase domain 8	0.015
Fgfr1	fibroblast growth factor receptor 1	0.015
Trem1	triggering receptor expressed on myeloid cells 1	0.014
Nkg7	natural killer cell group 7 sequence	0.014
Dock1	dedicator of cytokinesis 1	0.014
Fpr-rs3	formyl peptide receptor, related sequence 3	0.014	Mouse
Slc1a2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.014
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.014
Socs1	suppressor of cytokine signaling 1	0.014
Ccl20	chemokine (C-C motif) ligand 20	0.013
Fcamr	Fc receptor, IgA, IgM, high affinity	0.013
Ncf1	neutrophil cytosolic factor 1	0.013
Tgfb2	transforming growth factor, beta 2	0.013
Olfr1264	olfactory receptor 1264	0.013
Il27ra	interleukin 27 receptor, alpha	0.013
Lst1	leukocyte specific transcript 1	0.013
Tlr8	toll-like receptor 8	0.013
Olfr49	olfactory receptor 49	0.013
Itk	IL2-inducible T-cell kinase	0.013
Prrx1	paired related homeobox 1	0.013
C3	complement component 3	0.013
Tgfb1	transforming growth factor, beta 1	0.013
Trem3	triggering receptor expressed on myeloid cells 3	0.013
Il15ra	interleukin 15 receptor, alpha chain	0.012
Slfn3	schlafen 3	0.012
Ncf2	neutrophil cytosolic factor 2	0.012
Mmp7	matrix metallopeptidase 7	0.012
Fosl1	fos-like antigen 1	0.012
Lag3	lymphocyte-activation gene 3	0.012
C78513	EST C78513	0.012
Gpr37l1	G protein-coupled receptor 37-like 1	0.012
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.012
Foxp3	forkhead box P3	0.012
Was	Wiskott-Aldrich syndrome homolog (human)	0.012
Smurf2	SMAD specific E3 ubiquitin protein ligase 2	0.012
Hr	hairless	0.012
Pea15a	phosphoprotein enriched in astrocytes 15A	0.012
Fcrla	Fc receptor-like A	0.011
Cd209e	CD209e antigen	0.011
Krt6b	keratin 6B	0.011
Rnd3	Rho family GTPase 3	0.011
Sln	sarcolipin	0.011
Myd88	myeloid differentiation primary response gene 88	0.011
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.011
H2-Ob	histocompatibility 2, O region beta locus	0.011
2310014H01Rik	RIKEN cDNA 2310014H01 gene	0.011
Rgs5	regulator of G-protein signaling 5	0.011
F7	coagulation factor VII	0.011
A4galt	alpha 1,4-galactosyltransferase	0.011
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.011
Gdf9	growth differentiation factor 9	0.011
Ccr7	chemokine (C-C motif) receptor 7	0.011
Camp	cathelicidin antimicrobial peptide	0.011
Cma1	chymase 1, mast cell	0.011
Mpo	myeloperoxidase	0.011
Pf4	platelet factor 4	0.011
Sash3	SAM and SH3 domain containing 3	0.011
Cfl1	cofilin 1, non-muscle	0.011
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.011
Irf5	interferon regulatory factor 5	0.011
Ms4a1	membrane-spanning 4-domains, subfamily A, member 1	0.011
Spn	sialophorin	0.010
Ly6d	lymphocyte antigen 6 complex, locus D	0.010
Slamf8	SLAM family member 8	0.010
Pfn1	profilin 1	0.010
Adcy4	adenylate cyclase 4	0.010
Cldn5	claudin 5	0.010
Psg17	pregnancy specific glycoprotein 17	0.010
Tnfrsf17	tumor necrosis factor receptor superfamily, member 17	0.010
Casp14	caspase 14	0.010
Ltc4s	leukotriene C4 synthase	0.010
Mrgpra3	MAS-related GPR, member A3	0.010
Btk	Bruton agammaglobulinemia tyrosine kinase	0.010
Gng4	guanine nucleotide binding protein (G protein), gamma 4	0.010
St3gal1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	0.010
Pcdh12	protocadherin 12	0.010
Pglyrp1	peptidoglycan recognition protein 1	0.010
Pla2g2d	phospholipase A2, group IID	0.010