IMP

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Mus musculus

22 genes annotated in mouse

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regulation of natural killer cell activation

GO:0032814

Any process that modulates the frequency, rate or extent of natural killer cell activation.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of natural killer cell activation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of natural killer cell activation" (in gray)

Name	Description	Probability	Func Analog Organism
Slamf1	signaling lymphocytic activation molecule family member 1	0.998	Mouse
Tlr4	toll-like receptor 4	0.957
Stat1	signal transducer and activator of transcription 1	0.921	Mouse
Sh2d1b1	SH2 domain protein 1B1	0.910	Mouse
Ap3b1	adaptor-related protein complex 3, beta 1 subunit	0.910
Stat5a	signal transducer and activator of transcription 5A	0.903
Rab27a	RAB27A, member RAS oncogene family	0.868
Stat5b	signal transducer and activator of transcription 5B	0.841
Cno	cappuccino	0.798
Mitf	microphthalmia-associated transcription factor	0.744
Hps5	Hermansky-Pudlak syndrome 5 homolog (human)	0.712
Irf9	interferon regulatory factor 9	0.709
Hps6	Hermansky-Pudlak syndrome 6	0.699
Icos	inducible T-cell co-stimulator	0.617
Tyro3	TYRO3 protein tyrosine kinase 3	0.593
Ptprc	protein tyrosine phosphatase, receptor type, C	0.563
Il7r	interleukin 7 receptor	0.521
Il15ra	interleukin 15 receptor, alpha chain	0.516
Lair1	leukocyte-associated Ig-like receptor 1	0.493
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.412
Myd88	myeloid differentiation primary response gene 88	0.384
Cd28	CD28 antigen	0.366
Inpp5d	inositol polyphosphate-5-phosphatase D	0.361
Lck	lymphocyte protein tyrosine kinase	0.350
Ctsd	cathepsin D	0.334
Nckap1l	NCK associated protein 1 like	0.327
Cd244	CD244 natural killer cell receptor 2B4	0.301	Mouse
Stap1	signal transducing adaptor family member 1	0.280
Cst7	cystatin F (leukocystatin)	0.257
Plbd2	phospholipase B domain containing 2	0.244
Sh2d1a	SH2 domain protein 1A	0.244	Mouse
Il21r	interleukin 21 receptor	0.213
Il15	interleukin 15	0.213
Il2rg	interleukin 2 receptor, gamma chain	0.177
Hps3	Hermansky-Pudlak syndrome 3 homolog (human)	0.170
Ly9	lymphocyte antigen 9	0.169	Mouse
Hps4	Hermansky-Pudlak syndrome 4 homolog (human)	0.157
Muted	muted	0.152
Pdcd1lg2	programmed cell death 1 ligand 2	0.152
Vav1	vav 1 oncogene	0.149
Ticam1	toll-like receptor adaptor molecule 1	0.140
Foxp3	forkhead box P3	0.130
Hcst	hematopoietic cell signal transducer	0.126
Stat2	signal transducer and activator of transcription 2	0.120	Mouse
Pyhin1	pyrin and HIN domain family, member 1	0.116
Gpr65	G-protein coupled receptor 65	0.104
Cd247	CD247 antigen	0.103
Trim21	tripartite motif-containing 21	0.101
Rasgrp1	RAS guanyl releasing protein 1	0.097
Il4ra	interleukin 4 receptor, alpha	0.097
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.095
a	nonagouti	0.093
Mertk	c-mer proto-oncogene tyrosine kinase	0.092
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.089
Ap3d1	adaptor-related protein complex 3, delta 1 subunit	0.088
Ifnar1	interferon (alpha and beta) receptor 1	0.086
Apbb1ip	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	0.083
Cd3g	CD3 antigen, gamma polypeptide	0.082
Sla	src-like adaptor	0.079
Lyst	lysosomal trafficking regulator	0.078
Cd37	CD37 antigen	0.073
Sell	selectin, lymphocyte	0.071
Ccr9	chemokine (C-C motif) receptor 9	0.070
Gnrh1	gonadotropin releasing hormone 1	0.069
Ncoa3	nuclear receptor coactivator 3	0.069
Rhoh	ras homolog gene family, member H	0.068
Cd69	CD69 antigen	0.065
Arhgap9	Rho GTPase activating protein 9	0.065
Slamf7	SLAM family member 7	0.064
Was	Wiskott-Aldrich syndrome homolog (human)	0.063
Kit	kit oncogene	0.063
Itga4	integrin alpha 4	0.061
Sykb	spleen tyrosine kinase	0.060
Sash3	SAM and SH3 domain containing 3	0.060
Myo1f	myosin IF	0.059
Stat4	signal transducer and activator of transcription 4	0.059	Mouse
Hcls1	hematopoietic cell specific Lyn substrate 1	0.058
Dock2	dedicator of cyto-kinesis 2	0.057
Aif1	allograft inflammatory factor 1	0.057
Parvg	parvin, gamma	0.056
Cxcr6	chemokine (C-X-C motif) receptor 6	0.055
Ap1m1	adaptor-related protein complex AP-1, mu subunit 1	0.054
Cd72	CD72 antigen	0.052
Cblb	Casitas B-lineage lymphoma b	0.051
Rab38	RAB38, member of RAS oncogene family	0.049
Cd2	CD2 antigen	0.048
Gpr18	G protein-coupled receptor 18	0.048
Gzmb	granzyme B	0.047
Timp1	tissue inhibitor of metalloproteinase 1	0.047
Cd3d	CD3 antigen, delta polypeptide	0.047
Arhgap15	Rho GTPase activating protein 15	0.045
Igf1	insulin-like growth factor 1	0.045
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.044
Slamf8	SLAM family member 8	0.044
Lepr	leptin receptor	0.043
Gfi1	growth factor independent 1	0.043
Stat6	signal transducer and activator of transcription 6	0.042	Mouse
Nfil3	nuclear factor, interleukin 3, regulated	0.042
Rpl3	ribosomal protein L3	0.040
Dtnbp1	dystrobrevin binding protein 1	0.040
Fcrl1	Fc receptor-like 1	0.040
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.040
Pldn	pallidin	0.039
Ctsb	cathepsin B	0.039
Cd96	CD96 antigen	0.036
Klra17	killer cell lectin-like receptor, subfamily A, member 17	0.035
Gimap7	GTPase, IMAP family member 7	0.035
Slamf6	SLAM family member 6	0.034	Mouse
Slc2a8	solute carrier family 2, (facilitated glucose transporter), member 8	0.033
Mavs	mitochondrial antiviral signaling protein	0.032
Bcl2a1d	B-cell leukemia/lymphoma 2 related protein A1d	0.032
Evi2a	ecotropic viral integration site 2a	0.031
Nkg7	natural killer cell group 7 sequence	0.031
Havcr2	hepatitis A virus cellular receptor 2	0.031
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.029
Sp100	nuclear antigen Sp100	0.029
Emr4	EGF-like module containing, mucin-like, hormone receptor-like sequence 4	0.029
Hexa	hexosaminidase A	0.029
Il2rb	interleukin 2 receptor, beta chain	0.029
Lgals8	lectin, galactose binding, soluble 8	0.029
LOC677008	natural killer cell receptor 2B4-like	0.028
Abcg3	ATP-binding cassette, sub-family G (WHITE), member 3	0.028
Epsti1	epithelial stromal interaction 1 (breast)	0.028
Tnfrsf18	tumor necrosis factor receptor superfamily, member 18	0.027
Cd48	CD48 antigen	0.027	Mouse
Csprs	component of Sp100-rs	0.027
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.027
Lrmp	lymphoid-restricted membrane protein	0.026
Ifnar2	interferon (alpha and beta) receptor 2	0.026
Clec2i	C-type lectin domain family 2, member i	0.026
Slc24a5	solute carrier family 24, member 5	0.025
Cd27	CD27 antigen	0.025
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.025
Lpxn	leupaxin	0.024
5430427O19Rik	RIKEN cDNA 5430427O19 gene	0.024
Pi4kb	phosphatidylinositol 4-kinase, catalytic, beta polypeptide	0.024
Ccr5	chemokine (C-C motif) receptor 5	0.024
Rasal3	RAS protein activator like 3	0.024
Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	0.024
Clec4b1	C-type lectin domain family 4, member b1	0.023
Elf1	E74-like factor 1	0.023
Clec4a3	C-type lectin domain family 4, member a3	0.023
Adcy7	adenylate cyclase 7	0.023
Ms4a6b	membrane-spanning 4-domains, subfamily A, member 6B	0.023
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.022
Fam105a	family with sequence similarity 105, member A	0.022
Ms4a4b	membrane-spanning 4-domains, subfamily A, member 4B	0.022
Tmbim6	transmembrane BAX inhibitor motif containing 6	0.022
Tmem71	transmembrane protein 71	0.022
Cd200r1	CD200 receptor 1	0.022
Arid1b	AT rich interactive domain 1B (SWI-like)	0.022
BC147527	cDNA sequence BC147527	0.021
Batf	basic leucine zipper transcription factor, ATF-like	0.021
Tlr8	toll-like receptor 8	0.021
Sept7	septin 7	0.021
Bloc1s3	biogenesis of lysosome-related organelles complex-1, subunit 3	0.020
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.020
Evi2b	ecotropic viral integration site 2b	0.020
Clec4n	C-type lectin domain family 4, member n	0.020
Ebi3	Epstein-Barr virus induced gene 3	0.019
Traf3ip3	TRAF3 interacting protein 3	0.019
Itgal	integrin alpha L	0.019
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.018
Lat2	linker for activation of T cells family, member 2	0.018
Btla	B and T lymphocyte associated	0.018
Ccr7	chemokine (C-C motif) receptor 7	0.018
Il2	interleukin 2	0.018
Tep1	telomerase associated protein 1	0.018
Ikzf1	IKAROS family zinc finger 1	0.018
Selplg	selectin, platelet (p-selectin) ligand	0.018
Naip6	NLR family, apoptosis inhibitory protein 6	0.018
Gzma	granzyme A	0.017
Klrb1f	killer cell lectin-like receptor subfamily B member 1F	0.017
Pkib	protein kinase inhibitor beta, cAMP dependent, testis specific	0.017
Il16	interleukin 16	0.017
Rassf2	Ras association (RalGDS/AF-6) domain family member 2	0.017
Stx11	syntaxin 11	0.017
Cxcr3	chemokine (C-X-C motif) receptor 3	0.016
Gimap4	GTPase, IMAP family member 4	0.016
P2ry10	purinergic receptor P2Y, G-protein coupled 10	0.016
Xlr4a	X-linked lymphocyte-regulated 4A	0.016
5830405N20Rik	RIKEN cDNA 5830405N20 gene	0.016
Lax1	lymphocyte transmembrane adaptor 1	0.016
Nacc1	nucleus accumbens associated 1, BEN and BTB (POZ) domain containing	0.016
Psd4	pleckstrin and Sec7 domain containing 4	0.016
Rgs1	regulator of G-protein signaling 1	0.015
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.015
Itgax	integrin alpha X	0.015
Myo1g	myosin IG	0.015
Jak2	Janus kinase 2	0.015
Tbx21	T-box 21	0.015
AF251705	cDNA sequence AF251705	0.015
Themis	thymocyte selection associated	0.015
Gimap3	GTPase, IMAP family member 3	0.015
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.015
Cd53	CD53 antigen	0.014
Clec4a2	C-type lectin domain family 4, member a2	0.014
Rpl7	ribosomal protein L7	0.014
Tapbp	TAP binding protein	0.014
Klre1	killer cell lectin-like receptor family E member 1	0.014
Il17ra	interleukin 17 receptor A	0.014
Lcp2	lymphocyte cytosolic protein 2	0.014
Lgals9	lectin, galactose binding, soluble 9	0.014
Sema4d	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	0.014
Wrn	Werner syndrome homolog (human)	0.014
Cd81	CD81 antigen	0.014
Kmo	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.014
Arhgap30	Rho GTPase activating protein 30	0.014
Hpgds	hematopoietic prostaglandin D synthase	0.014
H2-K1	histocompatibility 2, K1, K region	0.013
Hmha1	histocompatibility (minor) HA-1	0.013
Lsp1	lymphocyte specific 1	0.013
A630033H20Rik	RIKEN cDNA A630033H20 gene	0.013
Pdcd6ip	programmed cell death 6 interacting protein	0.013
Ostm1	osteopetrosis associated transmembrane protein 1	0.013
Fyn	Fyn proto-oncogene	0.013
Snap29	synaptosomal-associated protein 29	0.013
H2-Oa	histocompatibility 2, O region alpha locus	0.013
Map4k1	mitogen-activated protein kinase kinase kinase kinase 1	0.013
Irak4	interleukin-1 receptor-associated kinase 4	0.013
Itgam	integrin alpha M	0.013
AW112010	expressed sequence AW112010	0.013
Gpr183	G protein-coupled receptor 183	0.013
Tlr1	toll-like receptor 1	0.013
Cytip	cytohesin 1 interacting protein	0.013
Ly75	lymphocyte antigen 75	0.013
Fam26f	family with sequence similarity 26, member F	0.013
Ccl5	chemokine (C-C motif) ligand 5	0.013
Adar	adenosine deaminase, RNA-specific	0.013
Cand1	cullin associated and neddylation disassociated 1	0.012
Aldh3b1	aldehyde dehydrogenase 3 family, member B1	0.012
Pilra	paired immunoglobin-like type 2 receptor alpha	0.012
Rc3h1	RING CCCH (C3H) domains 1	0.012
Rac2	RAS-related C3 botulinum substrate 2	0.012
Naip2	NLR family, apoptosis inhibitory protein 2	0.012
Aim2	absent in melanoma 2	0.012
Synpo	synaptopodin	0.012
Itgae	integrin alpha E, epithelial-associated	0.012
Traf3	TNF receptor-associated factor 3	0.012
Cd79b	CD79B antigen	0.012
Slc20a1	solute carrier family 20, member 1	0.012
Cd300a	CD300A antigen	0.012
P2ry12	purinergic receptor P2Y, G-protein coupled 12	0.012
Pak2	p21 protein (Cdc42/Rac)-activated kinase 2	0.012
Gm14085	predicted gene 14085	0.012
Pld4	phospholipase D family, member 4	0.012
Klrc3	killer cell lectin-like receptor subfamily C, member 3	0.011
Rad51l3	RAD51-like 3 (S. cerevisiae)	0.011
H2-D1	histocompatibility 2, D region locus 1	0.011
Fyb	FYN binding protein	0.011
Tspan32	tetraspanin 32	0.011
Fgd2	FYVE, RhoGEF and PH domain containing 2	0.011
Pik3r5	phosphoinositide-3-kinase, regulatory subunit 5, p101	0.011
Gzmk	granzyme K	0.011
Ncf4	neutrophil cytosolic factor 4	0.011
Tlr6	toll-like receptor 6	0.011
Ticam2	toll-like receptor adaptor molecule 2	0.011	Mouse
Gpr171	G protein-coupled receptor 171	0.011
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.011
Mospd3	motile sperm domain containing 3	0.011
Pstpip2	proline-serine-threonine phosphatase-interacting protein 2	0.011
Ltbp4	latent transforming growth factor beta binding protein 4	0.011
Nfya	nuclear transcription factor-Y alpha	0.011
Nbeal2	neurobeachin-like 2	0.011
Slc29a3	solute carrier family 29 (nucleoside transporters), member 3	0.011
Znfx1	zinc finger, NFX1-type containing 1	0.011
Stk10	serine/threonine kinase 10	0.011
Mthfr	5,10-methylenetetrahydrofolate reductase	0.011
Gpr174	G protein-coupled receptor 174	0.010
Prkcd	protein kinase C, delta	0.010
Rab19	RAB19, member RAS oncogene family	0.010
Il1r1	interleukin 1 receptor, type I	0.010
LOC100038947	signal-regulatory protein beta 1-like	0.010
Klrb1a	killer cell lectin-like receptor subfamily B member 1A	0.010
Pparg	peroxisome proliferator activated receptor gamma	0.010
Stam2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	0.010
Eef1b2	eukaryotic translation elongation factor 1 beta 2	0.010