IMP

Process View

Mus musculus

2 genes annotated in mouse

positive regulation of immune complex clearance by monocytes and macrophages

Any process that increases the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of immune complex clearance by monocytes and macrophages"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of immune complex clearance by monocytes and macrophages" (in gray)

Name	Description	Probability	Func Analog Organism
Ccr2	chemokine (C-C motif) receptor 2	1.000
Ccr5	chemokine (C-C motif) receptor 5	0.968	Mouse
Cd44	CD44 antigen	0.933
Mmp9	matrix metallopeptidase 9	0.923
Ccl3	chemokine (C-C motif) ligand 3	0.844
Ccl2	chemokine (C-C motif) ligand 2	0.817
Ccr6	chemokine (C-C motif) receptor 6	0.683	Mouse
Ccr1	chemokine (C-C motif) receptor 1	0.616	Mouse
Lepr	leptin receptor	0.584
Tlr4	toll-like receptor 4	0.567
Myd88	myeloid differentiation primary response gene 88	0.511
Tlr2	toll-like receptor 2	0.502
Xcr1	chemokine (C motif) receptor 1	0.462	Mouse
Ifng	interferon gamma	0.438
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.298
Lyz2	lysozyme 2	0.295
Il1r1	interleukin 1 receptor, type I	0.280
Sell	selectin, lymphocyte	0.250
Selp	selectin, platelet	0.245
Prdm1	PR domain containing 1, with ZNF domain	0.219
Ciita	class II transactivator	0.206
Cd7	CD7 antigen	0.197
Cxcl13	chemokine (C-X-C motif) ligand 13	0.189
Spp1	secreted phosphoprotein 1	0.170
Tnf	tumor necrosis factor	0.162
Cd180	CD180 antigen	0.152
Itk	IL2-inducible T-cell kinase	0.147
Fcer2a	Fc receptor, IgE, low affinity II, alpha polypeptide	0.144
Cx3cr1	chemokine (C-X3-C) receptor 1	0.142	Mouse
Il6	interleukin 6	0.130
Icam1	intercellular adhesion molecule 1	0.119
Il10	interleukin 10	0.116
Fcrla	Fc receptor-like A	0.115
Il12rb2	interleukin 12 receptor, beta 2	0.112
Slamf6	SLAM family member 6	0.109
Nos2	nitric oxide synthase 2, inducible	0.106
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.089
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.089
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.088
Lta	lymphotoxin A	0.087
Cxcr2	chemokine (C-X-C motif) receptor 2	0.086	Mouse
Blk	B lymphoid kinase	0.086
Itgax	integrin alpha X	0.084
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.083
Cd96	CD96 antigen	0.083
Ifngr1	interferon gamma receptor 1	0.079
Il15ra	interleukin 15 receptor, alpha chain	0.073
C5ar1	complement component 5a receptor 1	0.068
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.066
Il18rap	interleukin 18 receptor accessory protein	0.065
Gimap7	GTPase, IMAP family member 7	0.065
Pla2g2d	phospholipase A2, group IID	0.065
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.065
Icos	inducible T-cell co-stimulator	0.064
Foxp3	forkhead box P3	0.063
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.061
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.060
Efna1	ephrin A1	0.058
Fas	Fas (TNF receptor superfamily member 6)	0.055
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.054
Cxcr3	chemokine (C-X-C motif) receptor 3	0.054	Mouse
Fasl	Fas ligand (TNF superfamily, member 6)	0.054
Gzmb	granzyme B	0.054
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.052
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.052
Pparg	peroxisome proliferator activated receptor gamma	0.049
Il27ra	interleukin 27 receptor, alpha	0.048
Ldlr	low density lipoprotein receptor	0.048
Slamf1	signaling lymphocytic activation molecule family member 1	0.047
Sh2d2a	SH2 domain protein 2A	0.047
Art2a-ps	ADP-ribosyltransferase 2a, pseudogene	0.046
Cd6	CD6 antigen	0.046
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.045
S1pr4	sphingosine-1-phosphate receptor 4	0.044
Cox8c	cytochrome c oxidase, subunit VIIIc	0.044
Csf1	colony stimulating factor 1 (macrophage)	0.043
Sit1	suppression inducing transmembrane adaptor 1	0.043
Ncr1	natural cytotoxicity triggering receptor 1	0.041
Cd5	CD5 antigen	0.041
Elk4	ELK4, member of ETS oncogene family	0.040
H2-Ob	histocompatibility 2, O region beta locus	0.039
Ccr1l1	chemokine (C-C motif) receptor 1-like 1	0.039	Mouse
Ccr3	chemokine (C-C motif) receptor 3	0.038	Mouse
Bex6	brain expressed gene 6	0.038
Il18r1	interleukin 18 receptor 1	0.038
Il4	interleukin 4	0.038
Cd3e	CD3 antigen, epsilon polypeptide	0.038
Tspo2	translocator protein 2	0.037
Olfr49	olfactory receptor 49	0.037
Wisp2	WNT1 inducible signaling pathway protein 2	0.037
Gpr132	G protein-coupled receptor 132	0.035
Elf4	E74-like factor 4 (ets domain transcription factor)	0.034
Cd2	CD2 antigen	0.034
Cd40	CD40 antigen	0.033
Opn1mw	opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan)	0.032
Havcr2	hepatitis A virus cellular receptor 2	0.032
Tnfrsf17	tumor necrosis factor receptor superfamily, member 17	0.032
Spn	sialophorin	0.031
Pdcd1	programmed cell death 1	0.030
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.030
Olfr140	olfactory receptor 140	0.030
C3ar1	complement component 3a receptor 1	0.029
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.029
Itgae	integrin alpha E, epithelial-associated	0.029
LOC100502924	hypothetical protein LOC100502924	0.028
Apoe	apolipoprotein E	0.028
Cd4	CD4 antigen	0.027
Il1rl1	interleukin 1 receptor-like 1	0.027
Arl10	ADP-ribosylation factor-like 10	0.027
Oxt	oxytocin	0.027
Prg3	proteoglycan 3	0.027
Ccl4	chemokine (C-C motif) ligand 4	0.027
Il1b	interleukin 1 beta	0.027
Fgd3	FYVE, RhoGEF and PH domain containing 3	0.026
Pcdh12	protocadherin 12	0.026
Ccr4	chemokine (C-C motif) receptor 4	0.026	Mouse
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.025
Htr2b	5-hydroxytryptamine (serotonin) receptor 2B	0.025
Ccl17	chemokine (C-C motif) ligand 17	0.024
Il9r	interleukin 9 receptor	0.024
Mc2r	melanocortin 2 receptor	0.023
Itgal	integrin alpha L	0.023
Ear2	eosinophil-associated, ribonuclease A family, member 2	0.023
Tnfsf8	tumor necrosis factor (ligand) superfamily, member 8	0.023
Ikzf1	IKAROS family zinc finger 1	0.023
Igj	immunoglobulin joining chain	0.023
Art2b	ADP-ribosyltransferase 2b	0.023
Klra9	killer cell lectin-like receptor subfamily A, member 9	0.023
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.022
Tff1	trefoil factor 1	0.022
H2-M9	histocompatibility 2, M region locus 9	0.022
Ms4a1	membrane-spanning 4-domains, subfamily A, member 1	0.022
Gcet2	germinal center expressed transcript 2	0.022
Ccl7	chemokine (C-C motif) ligand 7	0.022
Il2rb	interleukin 2 receptor, beta chain	0.022
Mpo	myeloperoxidase	0.021
Gzmk	granzyme K	0.021
Irf4	interferon regulatory factor 4	0.021
Lep	leptin	0.021
Psp	parotid secretory protein	0.021
Il2ra	interleukin 2 receptor, alpha chain	0.021
Rhoh	ras homolog gene family, member H	0.020
Ccr8	chemokine (C-C motif) receptor 8	0.020	Mouse
Tlr7	toll-like receptor 7	0.020
Clec2i	C-type lectin domain family 2, member i	0.020
Folr2	folate receptor 2 (fetal)	0.020
Flt3	FMS-like tyrosine kinase 3	0.020
Lcn4	lipocalin 4	0.020
Ltb	lymphotoxin B	0.020
Itgam	integrin alpha M	0.020
Cysltr1	cysteinyl leukotriene receptor 1	0.019
Uts2r	urotensin 2 receptor	0.019
Fcrl1	Fc receptor-like 1	0.019
H2-Eb2	histocompatibility 2, class II antigen E beta2	0.019
Mmp12	matrix metallopeptidase 12	0.018
Bdkrb1	bradykinin receptor, beta 1	0.018
Sele	selectin, endothelial cell	0.018
Ccl22	chemokine (C-C motif) ligand 22	0.018
Pabpc2	poly(A) binding protein, cytoplasmic 2	0.018
Asprv1	aspartic peptidase, retroviral-like 1	0.018
Pdcd1lg2	programmed cell death 1 ligand 2	0.018
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.017
Hr	hairless	0.017
Dusp1	dual specificity phosphatase 1	0.017
Xcl1	chemokine (C motif) ligand 1	0.017
F2rl3	coagulation factor II (thrombin) receptor-like 3	0.016
Zan	zonadhesin	0.016
Retn	resistin	0.016
H2-Oa	histocompatibility 2, O region alpha locus	0.016
Rab3il1	RAB3A interacting protein (rabin3)-like 1	0.016
Grap2	GRB2-related adaptor protein 2	0.016
Cd8b1	CD8 antigen, beta chain 1	0.016
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.016
Mc1r	melanocortin 1 receptor	0.016
Kcna3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.016
Gdf9	growth differentiation factor 9	0.016
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.016
Enam	enamelin	0.015
Cd209a	CD209a antigen	0.015
Rhag	Rhesus blood group-associated A glycoprotein	0.015
Elane	elastase, neutrophil expressed	0.015
Cd207	CD207 antigen	0.015
Adamdec1	ADAM-like, decysin 1	0.015
Il15	interleukin 15	0.015
Cd8a	CD8 antigen, alpha chain	0.015
Vpreb3	pre-B lymphocyte gene 3	0.015
Oosp1	oocyte secreted protein 1	0.014
Tlr8	toll-like receptor 8	0.014
Cma1	chymase 1, mast cell	0.014
Fpr3	formyl peptide receptor 3	0.014
Soat2	sterol O-acyltransferase 2	0.014
Il1rn	interleukin 1 receptor antagonist	0.014
Slfn3	schlafen 3	0.014
Olfr1508	olfactory receptor 1508	0.014
Fmo3	flavin containing monooxygenase 3	0.014
Ptprc	protein tyrosine phosphatase, receptor type, C	0.014
Star	steroidogenic acute regulatory protein	0.014
Npy1r	neuropeptide Y receptor Y1	0.014
Cd19	CD19 antigen	0.014
Ly9	lymphocyte antigen 9	0.014
F2rl1	coagulation factor II (thrombin) receptor-like 1	0.014
Il7r	interleukin 7 receptor	0.014
Abcg3	ATP-binding cassette, sub-family G (WHITE), member 3	0.014
Tktl1	transketolase-like 1	0.014
Pou2f3	POU domain, class 2, transcription factor 3	0.014
Itga4	integrin alpha 4	0.014
Mmp8	matrix metallopeptidase 8	0.014
Gzmc	granzyme C	0.014
Tcstv3	2-cell-stage, variable group, member 3	0.014
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.014
Cd300ld	CD300 molecule-like family member d	0.014
Amac1	acyl-malonyl condensing enzyme 1	0.014
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.013
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.013
Rgs14	regulator of G-protein signaling 14	0.013
Cnga1	cyclic nucleotide gated channel alpha 1	0.013
Cxcr5	chemokine (C-X-C motif) receptor 5	0.013	Mouse
Cnr2	cannabinoid receptor 2 (macrophage)	0.013
Prg2	proteoglycan 2, bone marrow	0.013
Hmox1	heme oxygenase (decycling) 1	0.013
Opn1sw	opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)	0.013
Runx1	runt related transcription factor 1	0.013
Hpgds	hematopoietic prostaglandin D synthase	0.013
Dock1	dedicator of cytokinesis 1	0.013
Orm3	orosomucoid 3	0.013
Scgb1a1	secretoglobin, family 1A, member 1 (uteroglobin)	0.013
Ltf	lactotransferrin	0.013
Ucp3	uncoupling protein 3 (mitochondrial, proton carrier)	0.013
Gpr33	G protein-coupled receptor 33	0.013
Rfpl4	ret finger protein-like 4	0.013
Tssk1	testis-specific serine kinase 1	0.012
Myo1f	myosin IF	0.012
Reg3g	regenerating islet-derived 3 gamma	0.012
Car1	carbonic anhydrase 1	0.012
Casq1	calsequestrin 1	0.012
Slfn1	schlafen 1	0.012
Txk	TXK tyrosine kinase	0.012
Ikzf2	IKAROS family zinc finger 2	0.012
Cd3g	CD3 antigen, gamma polypeptide	0.012
Mcpt8	mast cell protease 8	0.012
Cd36	CD36 antigen	0.012
Tcl1b1	T-cell leukemia/lymphoma 1B, 1	0.012
Krt86	keratin 86	0.012
Serpinb7	serine (or cysteine) peptidase inhibitor, clade B, member 7	0.012
Akr1c6	aldo-keto reductase family 1, member C6	0.012
Nt5e	5' nucleotidase, ecto	0.012
Vdr	vitamin D receptor	0.012
Fcamr	Fc receptor, IgA, IgM, high affinity	0.012
Slfn4	schlafen 4	0.012
Cd46	CD46 antigen, complement regulatory protein	0.012
Dmbt1	deleted in malignant brain tumors 1	0.012
Calm4	calmodulin 4	0.012
Htr3a	5-hydroxytryptamine (serotonin) receptor 3A	0.012
Npy2r	neuropeptide Y receptor Y2	0.012
Fcgr1	Fc receptor, IgG, high affinity I	0.011
Rorc	RAR-related orphan receptor gamma	0.011
Cysltr2	cysteinyl leukotriene receptor 2	0.011
Cd209b	CD209b antigen	0.011
Gzma	granzyme A	0.011
Kmo	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.011
Cd3d	CD3 antigen, delta polypeptide	0.011
Pyhin1	pyrin and HIN domain family, member 1	0.011
Gpr133	G protein-coupled receptor 133	0.011
Gna15	guanine nucleotide binding protein, alpha 15	0.011
Vmn2r10	vomeronasal 2, receptor 10	0.011
Fpr-rs3	formyl peptide receptor, related sequence 3	0.011
B3gnt3	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3	0.011
Gpr34	G protein-coupled receptor 34	0.011
Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)	0.011
Galr2	galanin receptor 2	0.011
Tuba8	tubulin, alpha 8	0.011
Apbh	androgen-binding protein eta	0.011
Popdc2	popeye domain containing 2	0.011
Pramel7	preferentially expressed antigen in melanoma like 7	0.011
Mcpt1	mast cell protease 1	0.011
Fgf7	fibroblast growth factor 7	0.011
Pou2af1	POU domain, class 2, associating factor 1	0.011
Rpl39l	ribosomal protein L39-like	0.011
Zp2	zona pellucida glycoprotein 2	0.011
Cd1d2	CD1d2 antigen	0.011
Prl4a1	prolactin family 4, subfamily a, member 1	0.010
G6pc	glucose-6-phosphatase, catalytic	0.010
Entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.010
Itln1	intelectin 1 (galactofuranose binding)	0.010
Slc34a1	solute carrier family 34 (sodium phosphate), member 1	0.010
Il21r	interleukin 21 receptor	0.010
Gypa	glycophorin A	0.010
Edaradd	EDAR (ectodysplasin-A receptor)-associated death domain	0.010