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Mus musculus

27 genes annotated in mouse

pigment cell differentiation

The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "pigment cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "pigment cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Mitf	microphthalmia-associated transcription factor	1.000
Lyst	lysosomal trafficking regulator	1.000
Kit	kit oncogene	1.000
Trp53	transformation related protein 53	0.998
Rab27a	RAB27A, member RAS oncogene family	0.995
Vegfa	vascular endothelial growth factor A	0.995
Ap3b1	adaptor-related protein complex 3, beta 1 subunit	0.995
Tyr	tyrosinase	0.995	Zebrafish Mouse
a	nonagouti	0.993
Hps1	Hermansky-Pudlak syndrome 1 homolog (human)	0.992
Tyrp1	tyrosinase-related protein 1	0.992
Pax3	paired box gene 3	0.979	Zebrafish
Pax6	paired box gene 6	0.969
Ednrb	endothelin receptor type B	0.962
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.957
Pitx2	paired-like homeodomain transcription factor 2	0.943
Foxc1	forkhead box C1	0.933
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.932
Gli3	GLI-Kruppel family member GLI3	0.915
Sox2	SRY-box containing gene 2	0.913	Mouse
Ap3d1	adaptor-related protein complex 3, delta 1 subunit	0.902	Human
Tgfb1	transforming growth factor, beta 1	0.860
Psen1	presenilin 1	0.856	Zebrafish
Bmp4	bone morphogenetic protein 4	0.850
Oca2	oculocutaneous albinism II	0.792
Cno	cappuccino	0.782
Meox2	mesenchyme homeobox 2	0.760
Nos3	nitric oxide synthase 3, endothelial cell	0.760
Kitl	kit ligand	0.736
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.735
Pldn	pallidin	0.725
Hps6	Hermansky-Pudlak syndrome 6	0.721
Chd7	chromodomain helicase DNA binding protein 7	0.673
Tgfb2	transforming growth factor, beta 2	0.642
Flt1	FMS-like tyrosine kinase 1	0.638	Mouse
Hps4	Hermansky-Pudlak syndrome 4 homolog (human)	0.635
Hps5	Hermansky-Pudlak syndrome 5 homolog (human)	0.629
Notch2	Notch gene homolog 2 (Drosophila)	0.609
Ren1	renin 1 structural	0.594
Prrx1	paired related homeobox 1	0.577
Notch1	Notch gene homolog 1 (Drosophila)	0.549
Hdac4	histone deacetylase 4	0.514
Isl1	ISL1 transcription factor, LIM/homeodomain	0.508
Foxc2	forkhead box C2	0.508
Nf1	neurofibromatosis 1	0.464
Runx2	runt related transcription factor 2	0.429
Smo	smoothened homolog (Drosophila)	0.425
Fzd4	frizzled homolog 4 (Drosophila)	0.422
Acvr1	activin A receptor, type 1	0.422
Hand1	heart and neural crest derivatives expressed transcript 1	0.420
Jag1	jagged 1	0.414
Pou5f1	POU domain, class 5, transcription factor 1	0.407
Cbl	Casitas B-lineage lymphoma	0.404
Shh	sonic hedgehog	0.401
Rara	retinoic acid receptor, alpha	0.397
Mlph	melanophilin	0.396
Ctnnb1	catenin (cadherin associated protein), beta 1	0.385
Zeb1	zinc finger E-box binding homeobox 1	0.364	Mouse
Hand2	heart and neural crest derivatives expressed transcript 2	0.363
Pten	phosphatase and tensin homolog	0.356
Muted	muted	0.355
Fgf8	fibroblast growth factor 8	0.349
Tcfap2a	transcription factor AP-2, alpha	0.343	Zebrafish
Sox10	SRY-box containing gene 10	0.339
Usp8	ubiquitin specific peptidase 8	0.323
Efnb2	ephrin B2	0.296
Kdr	kinase insert domain protein receptor	0.292	Mouse
Rarb	retinoic acid receptor, beta	0.275
Fgfr2	fibroblast growth factor receptor 2	0.259
Vangl2	vang-like 2 (van gogh, Drosophila)	0.254
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.223	Mouse
Bcl2	B-cell leukemia/lymphoma 2	0.215
Cdh5	cadherin 5	0.214
Sall4	sal-like 4 (Drosophila)	0.212
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.177
Bax	BCL2-associated X protein	0.174	Mouse
Myo5a	myosin VA	0.174
Cldn5	claudin 5	0.162
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.157
Eya1	eyes absent 1 homolog (Drosophila)	0.157	Fly
Ednra	endothelin receptor type A	0.154	Mouse
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.153
Tgfbr2	transforming growth factor, beta receptor II	0.150
Msx2	homeobox, msh-like 2	0.140
Sox9	SRY-box containing gene 9	0.136	Mouse
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.133
Ncor2	nuclear receptor co-repressor 2	0.131
Gbx2	gastrulation brain homeobox 2	0.130
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.127
Agtr1a	angiotensin II receptor, type 1a	0.125
Adamts20	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20	0.114
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.113	Mouse
Sharpin	SHANK-associated RH domain interacting protein	0.111
Fgfr1	fibroblast growth factor receptor 1	0.110
Bcl6b	B-cell CLL/lymphoma 6, member B	0.109
Gli2	GLI-Kruppel family member GLI2	0.096	Mouse
Npr3	natriuretic peptide receptor 3	0.094
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.093
Rasip1	Ras interacting protein 1	0.092
Ncoa3	nuclear receptor coactivator 3	0.091
Mef2c	myocyte enhancer factor 2C	0.087
Bak1	BCL2-antagonist/killer 1	0.085	Mouse
Msx1	homeobox, msh-like 1	0.085
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.083
Otx2	orthodenticle homolog 2 (Drosophila)	0.079
Pmel	premelanosome protein	0.076
Ptprb	protein tyrosine phosphatase, receptor type, B	0.073
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.067
Klf6	Kruppel-like factor 6	0.065
Tcf4	transcription factor 4	0.064
Prf1	perforin 1 (pore forming protein)	0.064
Plxnd1	plexin D1	0.061
Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.060
Rab38	RAB38, member of RAS oncogene family	0.058	Human
Pcp2	Purkinje cell protein 2 (L7)	0.058
Nrp1	neuropilin 1	0.058
Sox18	SRY-box containing gene 18	0.058	Mouse
N4bp1	NEDD4 binding protein 1	0.058
Hes1	hairy and enhancer of split 1 (Drosophila)	0.057
Fli1	Friend leukemia integration 1	0.057
Neurog3	neurogenin 3	0.057
Gsc	goosecoid homeobox	0.056
Bmp2	bone morphogenetic protein 2	0.056
Cux1	cut-like homeobox 1	0.055
Ephb2	Eph receptor B2	0.055
Hif1a	hypoxia inducible factor 1, alpha subunit	0.055
Ncstn	nicastrin	0.054
Bdkrb2	bradykinin receptor, beta 2	0.054
Ret	ret proto-oncogene	0.054
Wdr26	WD repeat domain 26	0.053
Cpd	carboxypeptidase D	0.052
Foxi3	forkhead box I3	0.051
Adamts9	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9	0.050
Hps3	Hermansky-Pudlak syndrome 3 homolog (human)	0.049
Prrx2	paired related homeobox 2	0.049
Hoxa1	homeobox A1	0.047
Pdgfb	platelet derived growth factor, B polypeptide	0.046
Cenpj	centromere protein J	0.044
Tbx2	T-box 2	0.043
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.043
Aprt	adenine phosphoribosyl transferase	0.043
Grb10	growth factor receptor bound protein 10	0.042
She	src homology 2 domain-containing transforming protein E	0.042
Pxn	paxillin	0.042
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.041
Vegfc	vascular endothelial growth factor C	0.041
Smad3	MAD homolog 3 (Drosophila)	0.039
Tbx1	T-box 1	0.038
Emcn	endomucin	0.038
Adam17	a disintegrin and metallopeptidase domain 17	0.038
Gata4	GATA binding protein 4	0.038
Foxf2	forkhead box F2	0.037
Eda	ectodysplasin-A	0.037
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.037
Ntf3	neurotrophin 3	0.037
Ebf3	early B-cell factor 3	0.036
Kcnk3	potassium channel, subfamily K, member 3	0.036
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.035
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.035
Ptprm	protein tyrosine phosphatase, receptor type, M	0.035
Hdac7	histone deacetylase 7	0.035
Mfn2	mitofusin 2	0.035
Flt4	FMS-like tyrosine kinase 4	0.035	Mouse
Dll1	delta-like 1 (Drosophila)	0.034
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.034
Sox3	SRY-box containing gene 3	0.034	Mouse
Insm1	insulinoma-associated 1	0.033
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.033
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.032
Sall1	sal-like 1 (Drosophila)	0.032
Bcl2l1	BCL2-like 1	0.031	Mouse
Cd2ap	CD2-associated protein	0.031
Slc24a5	solute carrier family 24, member 5	0.031	Zebrafish
Rbms1	RNA binding motif, single stranded interacting protein 1	0.031
Ece1	endothelin converting enzyme 1	0.030
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.029
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.029
Epas1	endothelial PAS domain protein 1	0.028
Ptprg	protein tyrosine phosphatase, receptor type, G	0.028
Eng	endoglin	0.028
Fbln1	fibulin 1	0.028
Klf7	Kruppel-like factor 7 (ubiquitous)	0.027
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.027
Gna13	guanine nucleotide binding protein, alpha 13	0.027	Mouse
Zeb2	zinc finger E-box binding homeobox 2	0.026
Zic3	zinc finger protein of the cerebellum 3	0.026
Eps8	epidermal growth factor receptor pathway substrate 8	0.026
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.026
Rap2c	RAP2C, member of RAS oncogene family	0.025
Plac1	placental specific protein 1	0.025
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.025
Ski	ski sarcoma viral oncogene homolog (avian)	0.025
Myh9	myosin, heavy polypeptide 9, non-muscle	0.025
Cnot6	CCR4-NOT transcription complex, subunit 6	0.025
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.024
Apaf1	apoptotic peptidase activating factor 1	0.024
Mdm4	transformed mouse 3T3 cell double minute 4	0.024
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.024
Ikzf1	IKAROS family zinc finger 1	0.024
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.024
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.024
Cxcl12	chemokine (C-X-C motif) ligand 12	0.023
Rgs5	regulator of G-protein signaling 5	0.023
Csk	c-src tyrosine kinase	0.023
Hoxb3	homeobox B3	0.022
Lfng	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.022
Arsi	arylsulfatase i	0.022
Hoxa3	homeobox A3	0.022
Slc12a1	solute carrier family 12, member 1	0.021
Gja1	gap junction protein, alpha 1	0.021
Skil	SKI-like	0.021
Tinagl1	tubulointerstitial nephritis antigen-like 1	0.021
Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.021
Ap1g1	adaptor protein complex AP-1, gamma 1 subunit	0.021	Human
Arid3b	AT rich interactive domain 3B (BRIGHT-like)	0.020
Igf2	insulin-like growth factor 2	0.020
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.020
Nf2	neurofibromatosis 2	0.020
Tek	endothelial-specific receptor tyrosine kinase	0.020
Il6st	interleukin 6 signal transducer	0.020
Esam	endothelial cell-specific adhesion molecule	0.020
Jun	Jun oncogene	0.019
Atp6v0a1	ATPase, H+ transporting, lysosomal V0 subunit A1	0.019
Ptch2	patched homolog 2	0.019
Kdm2b	lysine (K)-specific demethylase 2B	0.019
Polr2a	polymerase (RNA) II (DNA directed) polypeptide A	0.019
5730559C18Rik	RIKEN cDNA 5730559C18 gene	0.019
Qk	quaking	0.019
Arhgef7	Rho guanine nucleotide exchange factor (GEF7)	0.019
Ap1m1	adaptor-related protein complex AP-1, mu subunit 1	0.019	Human
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.019
Bmp7	bone morphogenetic protein 7	0.019
Mdm2	transformed mouse 3T3 cell double minute 2	0.019
Igf2r	insulin-like growth factor 2 receptor	0.019
Gata6	GATA binding protein 6	0.019
Ppard	peroxisome proliferator activator receptor delta	0.018
Chmp1b	chromatin modifying protein 1B	0.018
Mgrn1	mahogunin, ring finger 1	0.018
Sp1	trans-acting transcription factor 1	0.018
Dtnbp1	dystrobrevin binding protein 1	0.018
Atp1b2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.018
Zic1	zinc finger protein of the cerebellum 1	0.017
Tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.017
Men1	multiple endocrine neoplasia 1	0.017
Rnpepl1	arginyl aminopeptidase (aminopeptidase B)-like 1	0.017
Sall3	sal-like 3 (Drosophila)	0.017
Cxcr4	chemokine (C-X-C motif) receptor 4	0.017
Fgf10	fibroblast growth factor 10	0.017
Cav1	caveolin 1, caveolae protein	0.017
Dach1	dachshund 1 (Drosophila)	0.017
Hesx1	homeobox gene expressed in ES cells	0.017
Acvrl1	activin A receptor, type II-like 1	0.017
Abcc9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	0.017
Pip5k1b	phosphatidylinositol-4-phosphate 5-kinase, type 1 beta	0.017
Heatr2	HEAT repeat containing 2	0.016
Pbx1	pre B-cell leukemia transcription factor 1	0.016
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.016
Egfr	epidermal growth factor receptor	0.016
Heyl	hairy/enhancer-of-split related with YRPW motif-like	0.016
Trap1a	tumor rejection antigen P1A	0.016
Barx2	BarH-like homeobox 2	0.016
Fhl3	four and a half LIM domains 3	0.016
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.016
Hif1an	hypoxia-inducible factor 1, alpha subunit inhibitor	0.016
Zic2	zinc finger protein of the cerebellum 2	0.016
Syt9	synaptotagmin IX	0.016
Nrk	Nik related kinase	0.016
Col4a2	collagen, type IV, alpha 2	0.015
Aplnr	apelin receptor	0.015
Alx4	aristaless-like homeobox 4	0.015
Hapln3	hyaluronan and proteoglycan link protein 3	0.015
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.015
Cyld	cylindromatosis (turban tumor syndrome)	0.015
Tox3	TOX high mobility group box family member 3	0.015
Gata3	GATA binding protein 3	0.015
Asxl1	additional sex combs like 1 (Drosophila)	0.015
Crebbp	CREB binding protein	0.015
Tbx3	T-box 3	0.015
Gja4	gap junction protein, alpha 4	0.015
Id1	inhibitor of DNA binding 1	0.015
Efna4	ephrin A4	0.015
Col1a1	collagen, type I, alpha 1	0.014
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.014
Cd93	CD93 antigen	0.014
Ptch1	patched homolog 1	0.014
Arhgef1	Rho guanine nucleotide exchange factor (GEF) 1	0.014
Adcy4	adenylate cyclase 4	0.014
Pou3f3	POU domain, class 3, transcription factor 3	0.014
Fam83g	family with sequence similarity 83, member G	0.014
Peg10	paternally expressed 10	0.014
Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	0.014
Pkd1	polycystic kidney disease 1 homolog	0.014
Ccdc96	coiled-coil domain containing 96	0.014
Dlx1	distal-less homeobox 1	0.014
Notch3	Notch gene homolog 3 (Drosophila)	0.014
Usp42	ubiquitin specific peptidase 42	0.013
Unc5c	unc-5 homolog C (C. elegans)	0.013
Snx18	sorting nexin 18	0.013
Gata2	GATA binding protein 2	0.013
Meox1	mesenchyme homeobox 1	0.013
Rhob	ras homolog gene family, member B	0.013
Prkce	protein kinase C, epsilon	0.013
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.013
Flii	flightless I homolog (Drosophila)	0.013
Dnajc5	DnaJ (Hsp40) homolog, subfamily C, member 5	0.013
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.013
Zbtb7b	zinc finger and BTB domain containing 7B	0.013
Kl	klotho	0.013
Mab21l2	mab-21-like 2 (C. elegans)	0.013
Tcf15	transcription factor 15	0.013
Prdm1	PR domain containing 1, with ZNF domain	0.013
Krt32	keratin 32	0.013
Tcfap2b	transcription factor AP-2 beta	0.013
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.012
Mcl1	myeloid cell leukemia sequence 1	0.012	Mouse
Fgd5	FYVE, RhoGEF and PH domain containing 5	0.012
Crxos1	Crx opposite strand transcript 1	0.012
Tcfap2c	transcription factor AP-2, gamma	0.012
Cotl1	coactosin-like 1 (Dictyostelium)	0.012
Foxa3	forkhead box A3	0.012
Car4	carbonic anhydrase 4	0.012
Usp25	ubiquitin specific peptidase 25	0.012
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.012
Foxd1	forkhead box D1	0.012
Amotl2	angiomotin-like 2	0.012
Sox17	SRY-box containing gene 17	0.012	Mouse
Sdk1	sidekick homolog 1 (chicken)	0.012
Hip1	huntingtin interacting protein 1	0.012
Trpv4	transient receptor potential cation channel, subfamily V, member 4	0.012
Acd	adrenocortical dysplasia	0.012
Map3k3	mitogen-activated protein kinase kinase kinase 3	0.012
Vav3	vav 3 oncogene	0.012
Zic4	zinc finger protein of the cerebellum 4	0.012
Sipa1	signal-induced proliferation associated gene 1	0.012
Cdh11	cadherin 11	0.012
Fuz	fuzzy homolog (Drosophila)	0.011
Fgf3	fibroblast growth factor 3	0.011
Bbc3	BCL2 binding component 3	0.011
Pomc	pro-opiomelanocortin-alpha	0.011
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.011
Lefty1	left right determination factor 1	0.011
Twist1	twist homolog 1 (Drosophila)	0.011
Gjb6	gap junction protein, beta 6	0.011
Edar	ectodysplasin-A receptor	0.011
Cdh6	cadherin 6	0.011
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.011
Gsx1	GS homeobox 1	0.011
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.011
Wasf2	WAS protein family, member 2	0.011
Tnfaip6	tumor necrosis factor alpha induced protein 6	0.011
Wdr86	WD repeat domain 86	0.011
Plxna2	plexin A2	0.011
Plvap	plasmalemma vesicle associated protein	0.011
Ldlr	low density lipoprotein receptor	0.011
Mpl	myeloproliferative leukemia virus oncogene	0.011
Edn1	endothelin 1	0.011	Mouse
Smad6	MAD homolog 6 (Drosophila)	0.011
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.011
A2m	alpha-2-macroglobulin	0.011
Cbs	cystathionine beta-synthase	0.011
Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform	0.011
Adam9	a disintegrin and metallopeptidase domain 9 (meltrin gamma)	0.011
Ctgf	connective tissue growth factor	0.011
Gltp	glycolipid transfer protein	0.011
Plce1	phospholipase C, epsilon 1	0.011
Drd4	dopamine receptor D4	0.011
Dlx2	distal-less homeobox 2	0.011
Midn	midnolin	0.010
Nr3c2	nuclear receptor subfamily 3, group C, member 2	0.010
Adra2a	adrenergic receptor, alpha 2a	0.010
Pde6b	phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide	0.010
Huwe1	HECT, UBA and WWE domain containing 1	0.010
Cdk14	cyclin-dependent kinase 14	0.010
Emid2	EMI domain containing 2	0.010
Abcd1	ATP-binding cassette, sub-family D (ALD), member 1	0.010
Ptpn12	protein tyrosine phosphatase, non-receptor type 12	0.010
Svil	supervillin	0.010
4632428N05Rik	RIKEN cDNA 4632428N05 gene	0.010
Pdzrn3	PDZ domain containing RING finger 3	0.010
Pak2	p21 protein (Cdc42/Rac)-activated kinase 2	0.010
Pi4kb	phosphatidylinositol 4-kinase, catalytic, beta polypeptide	0.010