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Mus musculus

18 genes annotated in mouse

muscle cell apoptotic process

A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "muscle cell apoptotic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "muscle cell apoptotic process" (in gray)

Name	Description	Probability	Func Analog Organism
Hand2	heart and neural crest derivatives expressed transcript 2	0.827
Pten	phosphatase and tensin homolog	0.796
Neurod1	neurogenic differentiation 1	0.782	Mouse
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.763
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.642
Isl1	ISL1 transcription factor, LIM/homeodomain	0.641
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.634
Emx1	empty spiracles homolog 1 (Drosophila)	0.581
Mdm2	transformed mouse 3T3 cell double minute 2	0.558
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.554
Ptf1a	pancreas specific transcription factor, 1a	0.473	Mouse
Shh	sonic hedgehog	0.405
Ddx60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.386
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.314
Hand1	heart and neural crest derivatives expressed transcript 1	0.297	Mouse
Trp53	transformation related protein 53	0.274
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.272
Nos3	nitric oxide synthase 3, endothelial cell	0.269
Hspa8	heat shock protein 8	0.267
Pdx1	pancreatic and duodenal homeobox 1	0.253
Sfrp2	secreted frizzled-related protein 2	0.230
Hr	hairless	0.187
Tbx3	T-box 3	0.184
Tgfb1	transforming growth factor, beta 1	0.169
Bdkrb2	bradykinin receptor, beta 2	0.154	Mouse
Lox	lysyl oxidase	0.139
Sfrp1	secreted frizzled-related protein 1	0.126	Mouse
Tgfbr2	transforming growth factor, beta receptor II	0.124
Flii	flightless I homolog (Drosophila)	0.119
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.118
Gata4	GATA binding protein 4	0.112
Agtr1a	angiotensin II receptor, type 1a	0.111
Tcf15	transcription factor 15	0.109	Mouse
Pthlh	parathyroid hormone-like peptide	0.108
Mecom	MDS1 and EVI1 complex locus	0.106
Ep300	E1A binding protein p300	0.103
Fgf8	fibroblast growth factor 8	0.102
Actn2	actinin alpha 2	0.098
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.094
Ren1	renin 1 structural	0.092
Mdm4	transformed mouse 3T3 cell double minute 4	0.088
Neurod4	neurogenic differentiation 4	0.086	Mouse
Hes5	hairy and enhancer of split 5 (Drosophila)	0.081
Grb10	growth factor receptor bound protein 10	0.080
Cdx2	caudal type homeobox 2	0.078
Nhlh1	nescient helix loop helix 1	0.077	Mouse
Tbx5	T-box 5	0.075
Pcdh12	protocadherin 12	0.072
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.070
Ntf3	neurotrophin 3	0.070
Nkx6-1	NK6 homeobox 1	0.069
Meox1	mesenchyme homeobox 1	0.068
Alx3	aristaless-like homeobox 3	0.065
Fgf17	fibroblast growth factor 17	0.065
Apc	adenomatosis polyposis coli	0.063
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.062
Foxc2	forkhead box C2	0.060
Rb1	retinoblastoma 1	0.060
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.060
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.059
Oasl2	2'-5' oligoadenylate synthetase-like 2	0.059
Gata1	GATA binding protein 1	0.058
Mesp1	mesoderm posterior 1	0.056
T	brachyury	0.056
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.055
Hoxd13	homeobox D13	0.055
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.054	Mouse
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.054
Mtap2	microtubule-associated protein 2	0.054
Fgf15	fibroblast growth factor 15	0.050
Pitx3	paired-like homeodomain transcription factor 3	0.049
Foxa2	forkhead box A2	0.048
Fbn1	fibrillin 1	0.045
Lhx5	LIM homeobox protein 5	0.044
Myh10	myosin, heavy polypeptide 10, non-muscle	0.043
En1	engrailed 1	0.043
Gp9	glycoprotein 9 (platelet)	0.043
Pax6	paired box gene 6	0.042
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.042
Prph2	peripherin 2	0.041
Glis3	GLIS family zinc finger 3	0.039
Cdh23	cadherin 23 (otocadherin)	0.039
Otp	orthopedia homolog (Drosophila)	0.039
Nkx3-2	NK3 homeobox 2	0.038	Mouse
Socs1	suppressor of cytokine signaling 1	0.038
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.038
Sfrp5	secreted frizzled-related sequence protein 5	0.037	Mouse
Onecut1	one cut domain, family member 1	0.036
Col1a1	collagen, type I, alpha 1	0.036
Irf7	interferon regulatory factor 7	0.035
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.035
Igf2r	insulin-like growth factor 2 receptor	0.035
Gsk3b	glycogen synthase kinase 3 beta	0.035
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.035
Wnt6	wingless-related MMTV integration site 6	0.034
Plec	plectin	0.033
Foxe1	forkhead box E1	0.033
Hspa1b	heat shock protein 1B	0.033
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.032
Vegfa	vascular endothelial growth factor A	0.032
Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.032
Rxra	retinoid X receptor alpha	0.032
Kiss1	KiSS-1 metastasis-suppressor	0.031
Igf2	insulin-like growth factor 2	0.031
Twist1	twist homolog 1 (Drosophila)	0.031	Mouse
Trim25	tripartite motif-containing 25	0.031
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.031
Agtrap	angiotensin II, type I receptor-associated protein	0.030
Utf1	undifferentiated embryonic cell transcription factor 1	0.030
Thbs1	thrombospondin 1	0.030
Braf	Braf transforming gene	0.029
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.028
Hoxd12	homeobox D12	0.028
Hes2	hairy and enhancer of split 2 (Drosophila)	0.028
Hes3	hairy and enhancer of split 3 (Drosophila)	0.028
Il11	interleukin 11	0.028
Foxd4	forkhead box D4	0.027
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.027
Gdnf	glial cell line derived neurotrophic factor	0.027
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.027
Prkdc	protein kinase, DNA activated, catalytic polypeptide	0.026
Hoxa1	homeobox A1	0.026
Ebf2	early B-cell factor 2	0.026
Akp3	alkaline phosphatase 3, intestine, not Mn requiring	0.026
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.026
Ghr	growth hormone receptor	0.025
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.025
Nos1	nitric oxide synthase 1, neuronal	0.025
Neurog2	neurogenin 2	0.025	Mouse
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.025
Myt1	myelin transcription factor 1	0.024
Ldb3	LIM domain binding 3	0.024
Dnm1	dynamin 1	0.024
Tsc1	tuberous sclerosis 1	0.023
Gata6	GATA binding protein 6	0.023
Npc1	Niemann Pick type C1	0.023
Insr	insulin receptor	0.023
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.023
Skil	SKI-like	0.022
Cited1	Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1	0.022
Tal1	T-cell acute lymphocytic leukemia 1	0.022	Mouse
Lmna	lamin A	0.022
Prkce	protein kinase C, epsilon	0.022
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.022
Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.022
Wnt3a	wingless-related MMTV integration site 3A	0.022
Gh	growth hormone	0.022
Myb	myeloblastosis oncogene	0.022
Pitx1	paired-like homeodomain transcription factor 1	0.021
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.021
Nrk	Nik related kinase	0.021
Pax9	paired box gene 9	0.021
Rprm	reprimo, TP53 dependent G2 arrest mediator candidate	0.021
Lhx3	LIM homeobox protein 3	0.021
Cit	citron	0.021
Gja5	gap junction protein, alpha 5	0.021
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.021
Mapk8	mitogen-activated protein kinase 8	0.021
Gfi1b	growth factor independent 1B	0.020
Foxf1a	forkhead box F1a	0.020
Irs1	insulin receptor substrate 1	0.020
Klk1b11	kallikrein 1-related peptidase b11	0.020
Msx1	homeobox, msh-like 1	0.020
Akap9	A kinase (PRKA) anchor protein (yotiao) 9	0.020
Btbd17	BTB (POZ) domain containing 17	0.019
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.019
Foxg1	forkhead box G1	0.019
Mdfi	MyoD family inhibitor	0.019
Gli2	GLI-Kruppel family member GLI2	0.019
Ptk2	PTK2 protein tyrosine kinase 2	0.019
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.018	Rat
Lepr	leptin receptor	0.018
Foxp3	forkhead box P3	0.018
Has2	hyaluronan synthase 2	0.018
Smn1	survival motor neuron 1	0.018
Dlk1	delta-like 1 homolog (Drosophila)	0.018
Neurog3	neurogenin 3	0.018	Mouse
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.018
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.017
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.017
Rax	retina and anterior neural fold homeobox	0.017
Prox1	prospero-related homeobox 1	0.017
Epha3	Eph receptor A3	0.017
Cenpj	centromere protein J	0.017
Adra2b	adrenergic receptor, alpha 2b	0.017
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.017
Tcf21	transcription factor 21	0.017
Insm1	insulinoma-associated 1	0.017
Omp	olfactory marker protein	0.017
Dcc	deleted in colorectal carcinoma	0.017
Ina	internexin neuronal intermediate filament protein, alpha	0.017
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.017
Mapk1	mitogen-activated protein kinase 1	0.017
Cdx1	caudal type homeobox 1	0.017
Tal2	T-cell acute lymphocytic leukemia 2	0.017	Mouse
Asb12	ankyrin repeat and SOCS box-containing 12	0.016
Dlg4	discs, large homolog 4 (Drosophila)	0.016
Phox2b	paired-like homeobox 2b	0.016
Arx	aristaless related homeobox	0.016
Kcnk3	potassium channel, subfamily K, member 3	0.016
BC057022	cDNA sequence BC057022	0.016
Alox12	arachidonate 12-lipoxygenase	0.016	Human
Nkx2-1	NK2 homeobox 1	0.016	Mouse
Krt14	keratin 14	0.016
Nsf	N-ethylmaleimide sensitive fusion protein	0.016
Mnx1	motor neuron and pancreas homeobox 1	0.016
Grid2ip	glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1	0.016
Hsph1	heat shock 105kDa/110kDa protein 1	0.016
Pou2f2	POU domain, class 2, transcription factor 2	0.016
Pax8	paired box gene 8	0.016
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.015	Mouse
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.015
Bdnf	brain derived neurotrophic factor	0.015
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.015
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.015
Cacng2	calcium channel, voltage-dependent, gamma subunit 2	0.015
Lrp5	low density lipoprotein receptor-related protein 5	0.015
Gna11	guanine nucleotide binding protein, alpha 11	0.015
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.015
Ifit1	interferon-induced protein with tetratricopeptide repeats 1	0.015
Gucy2e	guanylate cyclase 2e	0.015
Actn4	actinin alpha 4	0.015
Notch2	Notch gene homolog 2 (Drosophila)	0.015
Colq	collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase	0.015
Sox11	SRY-box containing gene 11	0.015
Espn	espin	0.015
Pofut1	protein O-fucosyltransferase 1	0.015
Huwe1	HECT, UBA and WWE domain containing 1	0.015
Col22a1	collagen, type XXII, alpha 1	0.015
5430421N21Rik	RIKEN cDNA 5430421N21 gene	0.015
Ctnnb1	catenin (cadherin associated protein), beta 1	0.015
Gnrh1	gonadotropin releasing hormone 1	0.015
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.014
Gip	gastric inhibitory polypeptide	0.014
Hoxc9	homeobox C9	0.014
Adam17	a disintegrin and metallopeptidase domain 17	0.014
Shox2	short stature homeobox 2	0.014
Rpl11	ribosomal protein L11	0.014
Prkcb	protein kinase C, beta	0.014
Tbr1	T-box brain gene 1	0.014
Trim10	tripartite motif-containing 10	0.014
Nppc	natriuretic peptide type C	0.014
Hoxa13	homeobox A13	0.014
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.014
Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.014
Col4a3	collagen, type IV, alpha 3	0.014
Neurog1	neurogenin 1	0.014	Mouse
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.014
Ager	advanced glycosylation end product-specific receptor	0.014
Msh2	mutS homolog 2 (E. coli)	0.014
Dlx2	distal-less homeobox 2	0.013
Tgfbr1	transforming growth factor, beta receptor I	0.013
Grm1	glutamate receptor, metabotropic 1	0.013
Twist2	twist homolog 2 (Drosophila)	0.013	Mouse
Wt1	Wilms tumor 1 homolog	0.013
Rfwd2	ring finger and WD repeat domain 2	0.013
Lmo2	LIM domain only 2	0.013
Dsc3	desmocollin 3	0.013
Obsl1	obscurin-like 1	0.013
Hic1	hypermethylated in cancer 1	0.013
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.013
Snai1	snail homolog 1 (Drosophila)	0.013
Cer1	cerberus 1 homolog (Xenopus laevis)	0.013
Tssk3	testis-specific serine kinase 3	0.013
Raf1	v-raf-leukemia viral oncogene 1	0.013
Gpr50	G-protein-coupled receptor 50	0.013
Cbl	Casitas B-lineage lymphoma	0.013
Prg2	proteoglycan 2, bone marrow	0.013
Rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.013
Umod	uromodulin	0.013
Gja4	gap junction protein, alpha 4	0.013
Atoh1	atonal homolog 1 (Drosophila)	0.013	Mouse
Drosha	drosha, ribonuclease type III	0.012
Hrh1	histamine receptor H1	0.012
Cbfa2t3	core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)	0.012
Pax1	paired box gene 1	0.012
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.012
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.012
Map3k6	mitogen-activated protein kinase kinase kinase 6	0.012
Hoxb4	homeobox B4	0.012
Cryba1	crystallin, beta A1	0.012
Hspb8	heat shock protein 8	0.012
Sox1	SRY-box containing gene 1	0.012
Myf5	myogenic factor 5	0.012
Pou3f2	POU domain, class 3, transcription factor 2	0.012
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.012
Whrn	whirlin	0.012
Mtap7d1	microtubule-associated protein 7 domain containing 1	0.012
Psen1	presenilin 1	0.012
Gipc3	GIPC PDZ domain containing family, member 3	0.012
Ctsg	cathepsin G	0.012
Chst8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8	0.012
Mecp2	methyl CpG binding protein 2	0.012
Irs3	insulin receptor substrate 3	0.012
Des	desmin	0.012
Xpa	xeroderma pigmentosum, complementation group A	0.012
Gbx1	gastrulation brain homeobox 1	0.011
Hbb-y	hemoglobin Y, beta-like embryonic chain	0.011
Atm	ataxia telangiectasia mutated homolog (human)	0.011
Arc	activity regulated cytoskeletal-associated protein	0.011
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.011
Sfn	stratifin	0.011
Spdef	SAM pointed domain containing ets transcription factor	0.011
Eln	elastin	0.011
Wnt5a	wingless-related MMTV integration site 5A	0.011
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.011
Nfe2	nuclear factor, erythroid derived 2	0.011
Ahr	aryl-hydrocarbon receptor	0.011
Olfr90	olfactory receptor 90	0.011
Prkcc	protein kinase C, gamma	0.011
Sftpc	surfactant associated protein C	0.011
Zic1	zinc finger protein of the cerebellum 1	0.011
Irs2	insulin receptor substrate 2	0.011
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.011
Pik3cb	phosphatidylinositol 3-kinase, catalytic, beta polypeptide	0.011
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.011
Zg16	zymogen granule protein 16	0.011
Shank2	SH3/ankyrin domain gene 2	0.011
Edn3	endothelin 3	0.011
Prph	peripherin	0.011
Hcrt	hypocretin	0.011
Nedd4	neural precursor cell expressed, developmentally down-regulated 4	0.011
Ldlr	low density lipoprotein receptor	0.011
Zic4	zinc finger protein of the cerebellum 4	0.011
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.011
Nf1	neurofibromatosis 1	0.011
Krt17	keratin 17	0.011
Dok1	docking protein 1	0.011
Igbp1b	immunoglobulin (CD79A) binding protein 1b	0.011
Edn2	endothelin 2	0.011
Lhx6	LIM homeobox protein 6	0.010
Elf1	E74-like factor 1	0.010
Efnb2	ephrin B2	0.010
Parp1	poly (ADP-ribose) polymerase family, member 1	0.010
Nbn	nibrin	0.010
Tcf3	transcription factor 3	0.010
Bhlhe22	basic helix-loop-helix family, member e22	0.010
Npas1	neuronal PAS domain protein 1	0.010
Fgf16	fibroblast growth factor 16	0.010
Wwox	WW domain-containing oxidoreductase	0.010
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.010
Kit	kit oncogene	0.010
Nkx2-6	NK2 transcription factor related, locus 6 (Drosophila)	0.010	Mouse
Pgr	progesterone receptor	0.010
Hspa1a	heat shock protein 1A	0.010
Vax1	ventral anterior homeobox containing gene 1	0.010
Shroom1	shroom family member 1	0.010
Tbx20	T-box 20	0.010