IMP

Process View

Mus musculus

2 genes annotated in mouse

cellular response to x ray

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to x ray"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cellular response to x ray" (in gray)

Name	Description	Probability	Func Analog Organism
Trp53	transformation related protein 53	0.994	Fly
Stat5b	signal transducer and activator of transcription 5B	0.974	Fly
Pten	phosphatase and tensin homolog	0.972
Stat5a	signal transducer and activator of transcription 5A	0.959	Fly
Stat3	signal transducer and activator of transcription 3	0.889
Kit	kit oncogene	0.864
Nos3	nitric oxide synthase 3, endothelial cell	0.850
Rxra	retinoid X receptor alpha	0.820
Foxp3	forkhead box P3	0.718
Col1a1	collagen, type I, alpha 1	0.709
Lepr	leptin receptor	0.691
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.639
Ar	androgen receptor	0.601
Sfrp1	secreted frizzled-related protein 1	0.593
Notch2	Notch gene homolog 2 (Drosophila)	0.531
Sfrp2	secreted frizzled-related protein 2	0.501
Esr1	estrogen receptor 1 (alpha)	0.468
Pparg	peroxisome proliferator activated receptor gamma	0.461
Tgfb1	transforming growth factor, beta 1	0.418
Smad3	MAD homolog 3 (Drosophila)	0.344
Mdm2	transformed mouse 3T3 cell double minute 2	0.326
Apc	adenomatosis polyposis coli	0.307
Hr	hairless	0.293
Apoe	apolipoprotein E	0.290
Rara	retinoic acid receptor, alpha	0.290
Vhl	von Hippel-Lindau tumor suppressor	0.277
Flt4	FMS-like tyrosine kinase 4	0.273
Kdr	kinase insert domain protein receptor	0.258
Emx1	empty spiracles homolog 1 (Drosophila)	0.205
Il6st	interleukin 6 signal transducer	0.203
Lyz2	lysozyme 2	0.186
Wnt5a	wingless-related MMTV integration site 5A	0.180
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.166
Rb1	retinoblastoma 1	0.166
Il4ra	interleukin 4 receptor, alpha	0.163
Wnt3a	wingless-related MMTV integration site 3A	0.160
Mdm4	transformed mouse 3T3 cell double minute 4	0.160
Ghr	growth hormone receptor	0.145
Trp73	transformation related protein 73	0.143	Fly
Fgfr2	fibroblast growth factor receptor 2	0.139
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.132
Ptgs2	prostaglandin-endoperoxide synthase 2	0.129
S1pr2	sphingosine-1-phosphate receptor 2	0.128
Sfn	stratifin	0.122
Itga3	integrin alpha 3	0.122
Trp63	transformation related protein 63	0.113	Fly
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.111
Lep	leptin	0.108
Fas	Fas (TNF receptor superfamily member 6)	0.097
Cav1	caveolin 1, caveolae protein	0.092
Vangl2	vang-like 2 (van gogh, Drosophila)	0.090
Fbln1	fibulin 1	0.086
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.086
Braf	Braf transforming gene	0.085
Col6a2	collagen, type VI, alpha 2	0.084
Sox4	SRY-box containing gene 4	0.082
Il1r1	interleukin 1 receptor, type I	0.077
Tlr4	toll-like receptor 4	0.076
Il10	interleukin 10	0.076
Ctnnb1	catenin (cadherin associated protein), beta 1	0.074
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.070
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.064
Prkdc	protein kinase, DNA activated, catalytic polypeptide	0.063
Itgb4	integrin beta 4	0.058
Ahr	aryl-hydrocarbon receptor	0.057
Thbs1	thrombospondin 1	0.056
Lama5	laminin, alpha 5	0.055
Ddr2	discoidin domain receptor family, member 2	0.051
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.050
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.050
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.049
Prlr	prolactin receptor	0.049
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.047
Sox18	SRY-box containing gene 18	0.047
Psen1	presenilin 1	0.044
Crct1	cysteine-rich C-terminal 1	0.043
Spna1	spectrin alpha 1	0.043
Twist1	twist homolog 1 (Drosophila)	0.043
Notch1	Notch gene homolog 1 (Drosophila)	0.041
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.040
Bcl2	B-cell leukemia/lymphoma 2	0.039
Shh	sonic hedgehog	0.039
Nckap1l	NCK associated protein 1 like	0.037
Ash1l	ash1 (absent, small, or homeotic)-like (Drosophila)	0.037
Csf1	colony stimulating factor 1 (macrophage)	0.035
Krt14	keratin 14	0.033
Ncoa3	nuclear receptor coactivator 3	0.032
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.032
Meox2	mesenchyme homeobox 2	0.032
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.032
Npr3	natriuretic peptide receptor 3	0.031
Egln1	EGL nine homolog 1 (C. elegans)	0.031
Clic3	chloride intracellular channel 3	0.031
Pecam1	platelet/endothelial cell adhesion molecule 1	0.030
Irf6	interferon regulatory factor 6	0.030
Ttc7	tetratricopeptide repeat domain 7	0.028
Hspb7	heat shock protein family, member 7 (cardiovascular)	0.028
Vdr	vitamin D receptor	0.028
Sufu	suppressor of fused homolog (Drosophila)	0.027
Epas1	endothelial PAS domain protein 1	0.027
Nos1	nitric oxide synthase 1, neuronal	0.027
Mmp9	matrix metallopeptidase 9	0.027
Fbln2	fibulin 2	0.026
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.026
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.026
Pdgfc	platelet-derived growth factor, C polypeptide	0.026
Smad4	MAD homolog 4 (Drosophila)	0.025
Lum	lumican	0.025
Pnpla2	patatin-like phospholipase domain containing 2	0.025
Skil	SKI-like	0.025
Fzd1	frizzled homolog 1 (Drosophila)	0.024
Egfr	epidermal growth factor receptor	0.024
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.023
Slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	0.022
Aes	amino-terminal enhancer of split	0.022
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.022
Tsc2	tuberous sclerosis 2	0.022
Cep350	centrosomal protein 350	0.022
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.022
Yap1	yes-associated protein 1	0.022
Dpt	dermatopontin	0.022
Adam17	a disintegrin and metallopeptidase domain 17	0.021
Klk8	kallikrein related-peptidase 8	0.021
Huwe1	HECT, UBA and WWE domain containing 1	0.021
Zfp503	zinc finger protein 503	0.021
Runx1	runt related transcription factor 1	0.020
Vegfa	vascular endothelial growth factor A	0.020	Fly
Phlda3	pleckstrin homology-like domain, family A, member 3	0.020
Atm	ataxia telangiectasia mutated homolog (human)	0.020
Amhr2	anti-Mullerian hormone type 2 receptor	0.020
Dab2	disabled homolog 2 (Drosophila)	0.020
Mlh1	mutL homolog 1 (E. coli)	0.020
Lamc2	laminin, gamma 2	0.019
Hbegf	heparin-binding EGF-like growth factor	0.019
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.019
Smtn	smoothelin	0.018
Hspb1	heat shock protein 1	0.018
Islr	immunoglobulin superfamily containing leucine-rich repeat	0.018
Trim29	tripartite motif-containing 29	0.018
Esr2	estrogen receptor 2 (beta)	0.018
Steap3	STEAP family member 3	0.018
Stat1	signal transducer and activator of transcription 1	0.018
Gpc3	glypican 3	0.018
Thbs2	thrombospondin 2	0.018
Foxo1	forkhead box O1	0.018
Thra	thyroid hormone receptor alpha	0.017
Gas1	growth arrest specific 1	0.017
Flt1	FMS-like tyrosine kinase 1	0.017
Snta1	syntrophin, acidic 1	0.017
Kitl	kit ligand	0.017
Sod3	superoxide dismutase 3, extracellular	0.017
Nid2	nidogen 2	0.016
Hk1	hexokinase 1	0.016
C1qtnf1	C1q and tumor necrosis factor related protein 1	0.016
Adipoq	adiponectin, C1Q and collagen domain containing	0.016
Naalad2	N-acetylated alpha-linked acidic dipeptidase 2	0.016
Slc27a1	solute carrier family 27 (fatty acid transporter), member 1	0.016
Lef1	lymphoid enhancer binding factor 1	0.016
Hipk1	homeodomain interacting protein kinase 1	0.016
Mmp11	matrix metallopeptidase 11	0.016
Mapk14	mitogen-activated protein kinase 14	0.016
Capn1	calpain 1	0.016
Aebp1	AE binding protein 1	0.016
Tapbp	TAP binding protein	0.016
Drap1	Dr1 associated protein 1 (negative cofactor 2 alpha)	0.015
Sgk3	serum/glucocorticoid regulated kinase 3	0.015
Cd44	CD44 antigen	0.015
Ano1	anoctamin 1, calcium activated chloride channel	0.015
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.015
Lmna	lamin A	0.015
Map3k1	mitogen-activated protein kinase kinase kinase 1	0.015
Spp1	secreted phosphoprotein 1	0.015
Tgfbr2	transforming growth factor, beta receptor II	0.015
Cdx2	caudal type homeobox 2	0.015
Gys1	glycogen synthase 1, muscle	0.015
Cd34	CD34 antigen	0.015
Mfap2	microfibrillar-associated protein 2	0.015
Smn1	survival motor neuron 1	0.015
Ndn	necdin	0.015
Ccnd1	cyclin D1	0.015
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.014
Anxa8	annexin A8	0.014
Lama4	laminin, alpha 4	0.014
Hhat	hedgehog acyltransferase	0.014
Emcn	endomucin	0.014
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.014
Myom1	myomesin 1	0.014
Tek	endothelial-specific receptor tyrosine kinase	0.014
Ptges	prostaglandin E synthase	0.014
Tcf12	transcription factor 12	0.014
Tmem45a	transmembrane protein 45a	0.014
Bcat2	branched chain aminotransferase 2, mitochondrial	0.014
Gata3	GATA binding protein 3	0.014	Human
Emp2	epithelial membrane protein 2	0.014
Aoc3	amine oxidase, copper containing 3	0.014
Tcf21	transcription factor 21	0.013
Dll1	delta-like 1 (Drosophila)	0.013
Akt2	thymoma viral proto-oncogene 2	0.013
Igf1	insulin-like growth factor 1	0.013
Tgfb1i1	transforming growth factor beta 1 induced transcript 1	0.013
Mfap5	microfibrillar associated protein 5	0.013
Ifrd2	interferon-related developmental regulator 2	0.013
Agtr1a	angiotensin II receptor, type 1a	0.013
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.013
Angptl2	angiopoietin-like 2	0.013
Socs1	suppressor of cytokine signaling 1	0.013
Rasip1	Ras interacting protein 1	0.013
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.013
Tbx3	T-box 3	0.013
Bmp4	bone morphogenetic protein 4	0.013
Arhgap8	Rho GTPase activating protein 8	0.013
Ep300	E1A binding protein p300	0.012
Fam69b	family with sequence similarity 69, member B	0.012
Stk11	serine/threonine kinase 11	0.012
Tgfbr3	transforming growth factor, beta receptor III	0.012
Cnot4	CCR4-NOT transcription complex, subunit 4	0.012
Cd248	CD248 antigen, endosialin	0.012
Trpc2	transient receptor potential cation channel, subfamily C, member 2	0.012
Pdpn	podoplanin	0.012
Fbn1	fibrillin 1	0.012
Eng	endoglin	0.012
Ap3b1	adaptor-related protein complex 3, beta 1 subunit	0.012
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.012
Pld2	phospholipase D2	0.012
Prkci	protein kinase C, iota	0.012
Ins2	insulin II	0.012
Trpv4	transient receptor potential cation channel, subfamily V, member 4	0.012
Sfrp5	secreted frizzled-related sequence protein 5	0.012	Mouse
Mll3	myeloid/lymphoid or mixed-lineage leukemia 3	0.012
Ldlr	low density lipoprotein receptor	0.012
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.012
Arid4a	AT rich interactive domain 4A (RBP1-like)	0.012
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.012
Thbd	thrombomodulin	0.012
Clec3b	C-type lectin domain family 3, member b	0.011
Abcd1	ATP-binding cassette, sub-family D (ALD), member 1	0.011
Rarg	retinoic acid receptor, gamma	0.011
H2-Ke6	H2-K region expressed gene 6	0.011
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.011
Nf2	neurofibromatosis 2	0.011
Rhbdl3	rhomboid, veinlet-like 3 (Drosophila)	0.011
Mall	mal, T-cell differentiation protein-like	0.011
Lima1	LIM domain and actin binding 1	0.011
Klf4	Kruppel-like factor 4 (gut)	0.011
Met	met proto-oncogene	0.011
Lmod2	leiomodin 2 (cardiac)	0.011
Gpx7	glutathione peroxidase 7	0.011
Wdsub1	WD repeat, SAM and U-box domain containing 1	0.011
Mrvi1	MRV integration site 1	0.011
Tmem54	transmembrane protein 54	0.011
Dpysl3	dihydropyrimidinase-like 3	0.011
Tnni1	troponin I, skeletal, slow 1	0.011
Sirt2	sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)	0.011
Pvr	poliovirus receptor	0.011
Rspo1	R-spondin homolog (Xenopus laevis)	0.011
Zmynd11	zinc finger, MYND domain containing 11	0.011
Ptk7	PTK7 protein tyrosine kinase 7	0.011
Cox8b	cytochrome c oxidase, subunit VIIIb	0.011
Cables1	CDK5 and Abl enzyme substrate 1	0.011
Slc11a2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2	0.011
Ube2r2	ubiquitin-conjugating enzyme E2R 2	0.011
Crabp2	cellular retinoic acid binding protein II	0.011
Obfc2b	oligonucleotide/oligosaccharide-binding fold containing 2B	0.011
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.011
Rrad	Ras-related associated with diabetes	0.011
Eln	elastin	0.010
Brca2	breast cancer 2	0.010
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.010
Iqgap1	IQ motif containing GTPase activating protein 1	0.010
St3gal2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	0.010
Nrk	Nik related kinase	0.010
Gadd45a	growth arrest and DNA-damage-inducible 45 alpha	0.010
Cbr2	carbonyl reductase 2	0.010
Usf2	upstream transcription factor 2	0.010
Zbtb7b	zinc finger and BTB domain containing 7B	0.010
Ppp1r3c	protein phosphatase 1, regulatory (inhibitor) subunit 3C	0.010
Ttc16	tetratricopeptide repeat domain 16	0.010
Cldn5	claudin 5	0.010
Bves	blood vessel epicardial substance	0.010
Efs	embryonal Fyn-associated substrate	0.010