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Danio rerio

2 genes annotated in zebrafish

Multi-species View

negative regulation of muscle tissue development

GO:1901862

Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of muscle tissue development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of muscle tissue development" (in gray)

Name	Description	Probability	Func Analog Organism
bmp2b	bone morphogenetic protein 2b	0.952	Human
bmp4	bone morphogenetic protein 4	0.867	Human
wnt5b	wingless-type MMTV integration site family, member 5b	0.681
chd	chordin	0.505
myod1	myogenic differentiation 1	0.504
pitx2	paired-like homeodomain transcription factor 2	0.376
hoxa9b	homeo box A9b	0.335
hoxa11b	homeo box A11b	0.329
dlx5a	distal-less homeobox gene 5a	0.275
osr1	odd-skipped related 1 (Drosophila)	0.230
mstnb	myostatin b	0.230
hoxa11a	homeo box A11a	0.226
foxa3	forkhead box A3	0.225
fgf24	fibroblast growth factor 24	0.210
pcdh8	protocadherin 8	0.201
bmp2a	bone morphogenetic protein 2a	0.201	Human
fsta	follistatin a	0.185
hoxd11a	homeo box D11a	0.174
dkk1b	dickkopf 1b	0.159	Mouse
msxc	muscle segment homeobox C	0.154
tbx2a	T-box gene 2a	0.148
hoxd10a	homeo box D10a	0.145
fabp11a	fatty acid binding protein 11a	0.144
gpr126	G protein-coupled receptor 126	0.139
nkx2.5	NK2 transcription factor related 5	0.138
hoxd13a	homeo box D13a	0.132
hoxa13b	homeo box A13b	0.118
six4a	sine oculis homeobox homolog 4a	0.118
hoxa10b	homeo box A10b	0.115
hoxa13a	homeo box A13a	0.110
tbx18	T-box 18	0.106
foxd5	forkhead box D5	0.102
myf5	myogenic factor 5	0.093
fgf3	fibroblast growth factor 3	0.090
hoxc6a	homeo box C6a	0.086
vcana	versican a	0.081
tbx1	T-box 1	0.080
tbx5b	T-box 5b	0.080
slc6a6	solute carrier family 6 (neurotransmitter transporter, taurine), member 6	0.080
tbx2b	T-box 2b	0.079
tgfb3	transforming growth factor, beta 3	0.078
hoxa9a	homeo box A9a	0.077
hoxd9a	homeo box D9a	0.072
foxa1	forkhead box A1	0.072
klf4	Kruppel-like factor 4	0.071
hand2	heart and neural crest derivatives expressed transcript 2	0.070
fgf4	fibroblast growth factor 4	0.069
msxd	muscle segment homeobox D	0.067
myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.066
mstna	myostatin a	0.063	Zebrafish
pkd2	polycystic kidney disease 2	0.062
spry2	sprouty homolog 2	0.056
fgf10a	fibroblast growth factor 10a	0.056
nkd1	naked cuticle homolog 1 (Drosophila)	0.055
igf2a	insulin-like growth factor 2a	0.054
notch1a	notch homolog 1a	0.054
foxa2	forkhead box A2	0.053
hoxd4a	homeo box D4a	0.052
hoxb1b	homeo box B1b	0.051
lft1	lefty1	0.050
gata5	GATA-binding protein 5	0.048
eve1	even-skipped-like1	0.047
prickle1a	prickle-like 1 (Drosophila) a	0.045	Human
hoxc10a	homeo box C10a and homeobox protein Hox-C10a-like	0.044
evx2	even-skipped homeobox 2	0.044
hoxb5b	homeo box B5b	0.044
chsy1	chondroitin sulfate synthase 1	0.044
hprt1	hypoxanthine phosphoribosyltransferase 1	0.042
dhrs3a	dehydrogenase/reductase (SDR family) member 3a	0.042
admp	anti-dorsalizing morphogenic protein	0.042
cx30.3	connexin 30.3	0.041
cxcr4a	chemokine (C-X-C motif) receptor 4a	0.041
cx27.5	connexin 27.5	0.041
kdrl	kinase insert domain receptor like	0.040
mapk3	mitogen-activated protein kinase 3	0.039
shhb	sonic hedgehog b	0.038	Mouse
dct	dopachrome tautomerase	0.037
gata6	GATA-binding protein 6	0.036
tfap2c	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.036
fgfrl1b	fibroblast growth factor receptor-like 1b	0.036
crabp1b	cellular retinoic acid binding protein 1b	0.036
has2	hyaluronan synthase 2	0.035
dlx4a	distal-less homeobox gene 4a	0.035
nkx2.3	NK2 transcription factor related 3	0.035
hspb7	heat shock protein family, alpha-crystallin-related, b7	0.034
wt1a	wilms tumor 1a	0.034
msxb	muscle segment homeobox B	0.034
nppa	natriuretic peptide precursor A	0.033
frem2a	Fras1 related extracellular matrix protein 2a	0.033
hoxc9a	homeo box C9a	0.033
podxl	podocalyxin-like	0.032
lama4	laminin, alpha 4	0.032
acvr1b	activin A receptor, type IB	0.032
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.032
cldn12	claudin 12	0.032
bambia	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a	0.031
itga3b	integrin, alpha 3b	0.031
cacnb4a	calcium channel, voltage-dependent, beta 4a subunit	0.031
nog1	noggin 1	0.031	Mouse
ednra	endothelin receptor type A	0.030
lmna	lamin A	0.030
twist3	twist3	0.030
lmo4a	LIM domain only 4a	0.030
sox17	SRY-box containing gene 17	0.030
tp73	tumor protein p73	0.030	Human
cyp1a	cytochrome P450, family 1, subfamily A	0.029
nog3	noggin 3	0.029
vasn	vasorin	0.029
nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.028
sp5	Sp5 transcription factor	0.028
sox9a	SRY-box containing gene 9a	0.027
apobec2a	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a	0.027
col8a1a	collagen, type VIII, alpha 1a	0.026
smyd1b	SET and MYND domain containing 1b	0.026
socs1	suppressor of cytokine signaling 1	0.026
fgfr4	fibroblast growth factor receptor 4	0.026
sdc2	syndecan 2	0.025
tm9sf4	transmembrane 9 superfamily protein member 4	0.025
prrx1a	paired related homeobox 1a	0.025
vmhc	ventricular myosin heavy chain	0.025
slit3	slit (Drosophila) homolog 3	0.025
card14	caspase recruitment domain family, member 14	0.024
snai2	snail homolog 2 (Drosophila)	0.024
mtp	microsomal triglyceride transfer protein	0.024
eng1a	engrailed 1a	0.024
pea3	ETS-domain transcription factor pea3	0.023
cxcl12b	chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)	0.023
pdlim7	PDZ and LIM domain 7	0.023
tp63	tumor protein p63	0.023
lft2	lefty2	0.023
sgk1	serum/glucocorticoid regulated kinase 1	0.023
lhx1a	LIM homeobox 1a	0.022
scinla	scinderin like a	0.022
smyd1a	SET and MYND domain containing 1a	0.022
myl7	myosin, light polypeptide 7, regulatory	0.022
gata4	GATA-binding protein 4	0.022
rasl11b	RAS-like, family 11, member B	0.022
prox2	prospero homeobox 2	0.022
ighm	immunoglobulin heavy constant mu and immunoglobulin heavy constant mu	0.021
egfra	epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)	0.021
pax9	paired box gene 9	0.021
hoxc8a	homeo box C8a	0.021
frzb	frizzled-related protein	0.021
kiss1rb	KISS1 receptor b	0.021
og9x	OG9 homeobox gene	0.021
si:ch211-195h23.3	si:ch211-195h23.3	0.021
gbx2	gastrulation brain homeo box 2	0.020
myog	myogenin	0.020
osr2	odd-skipped related 2 (Drosophila)	0.020
spsb1	splA/ryanodine receptor domain and SOCS box containing 1	0.020
sat1b	spermidine/spermine N1-acetyl transferase 1b	0.020
fras1	Fraser syndrome 1	0.020
crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.020
wif1	wnt inhibitory factor 1	0.020
bmp3	bone morphogenetic protein 3	0.020
ptpn21	protein tyrosine phosphatase, non-receptor type 21	0.020
per2	period homolog 2 (Drosophila)	0.020
gdf6a	growth differentiation factor 6a	0.020
hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.020
tm9sf3	transmembrane 9 superfamily member 3	0.020
tbx3	T-box 3	0.020
xirp1	xin actin-binding repeat containing 1	0.020
kiss1	KiSS-1 metastasis-suppressor	0.020
myca	myelocytomatosis oncogene a	0.020
shha	sonic hedgehog a	0.020	Mouse
msxa	muscle segment homeobox A	0.020
barx2	BarH-like homeobox 2	0.020
si:dkey-24g18.2	si:dkey-24g18.2	0.020
ptgs1	prostaglandin-endoperoxide synthase 1	0.020
nr2e3	nuclear receptor subfamily 2, group E, member 3	0.019
cdkl1	cyclin-dependent kinase-like 1 (CDC2-related kinase)	0.019
lbx2	ladybird homeobox homolog 2 (Drosophila)	0.019
mef2cb	myocyte enhancer factor 2cb	0.019
fgf17	fibroblast growth factor 17	0.019
sulf1	sulfatase 1	0.019
robo2	roundabout homolog 2	0.019
rx1	retinal homeobox gene 1	0.019
zgc:55558	zgc:55558	0.019
scn4ab	sodium channel, voltage-gated, type IV, alpha, b	0.019
tert	telomerase reverse transcriptase	0.019
igf2b	insulin-like growth factor 2b	0.019
itgb1a	integrin, beta 1a	0.018
ucp3	uncoupling protein 3	0.018
dnmt3	DNA (cytosine-5-)-methyltransferase 3	0.018
jun	jun proto-oncogene	0.018
bcl2l1	bcl2-like 1	0.018
foxc1a	forkhead box C1a	0.018
her7	hairy and enhancer of split related-7	0.018
npnt	nephronectin	0.018
th	tyrosine hydroxylase	0.018
ved	ventrally expressed dharma/bozozok antagonist	0.018
tbx5a	T-box 5a	0.018	Human
wt1b	wilms tumor 1b	0.018
esama	endothelial cell adhesion molecule a	0.018
igfbp3	insulin-like growth factor binding protein 3	0.018
fabp7b	fatty acid binding protein 7, brain, b	0.018
col2a1a	collagen type II, alpha-1a	0.018
atp2a2a	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a	0.018
tgfbr2	transforming growth factor, beta receptor II	0.017	Rat
nt5e	5'-nucleotidase, ecto (CD73)	0.017
slc2a10	solute carrier family 2 (facilitated glucose transporter), member 10	0.017
plekha7	pleckstrin homology domain containing, family A member 7	0.017
twist2	twist2	0.017
vsx2	visual system homeobox 2	0.017
fstl1a	follistatin-like 1a	0.017
si:dkey-8l13.4	si:dkey-8l13.4	0.017
ptpn1	protein tyrosine phosphatase, non-receptor type 1	0.017
b2m	beta-2-microglobulin	0.017
tpm4	tropomyosin 4	0.017
klf11b	Kruppel-like factor 11b	0.017
yrk	Yes-related kinase	0.017
prnprs1	prion protein, related sequence 1	0.017
s100z	S100 calcium binding protein Z	0.017
lhx6	LIM homeobox 6	0.016
adra2db	adrenergic, alpha-2D-, receptor b	0.016
slc8a4a	solute carrier family 8 (sodium/calcium exchanger), member 4a	0.016
gna12	guanine nucleotide binding protein (G protein) alpha 12	0.016
nrg1	neuregulin 1	0.016
crabp2b	cellular retinoic acid binding protein 2, b	0.016
LOC100332929	guanine nucleotide-binding protein subunit alpha-15-like	0.016
tbp	TATA box binding protein	0.016
myhz2	myosin, heavy polypeptide 2, fast muscle specific	0.016
epas1b	endothelial PAS domain protein 1b	0.016
wnt2ba	wingless-type MMTV integration site family, member 2Ba	0.016
lnpa	limb and neural patterns a	0.016
bmp7b	bone morphogenetic protein 7b	0.016
cdx1a	caudal type homeo box transcription factor 1 a	0.016
dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.016
tbx20	T-box 20	0.016
LOC100004296	novel protein similar to murine T brachyury (T)	0.016
adra2b	adrenergic, alpha-2B-, receptor	0.016
zgc:56062	zgc:56062	0.016
axin2	axin 2 (conductin, axil)	0.016
ldb1a	LIM-domain binding factor 1a	0.016
plrg1	pleiotropic regulator 1	0.015
tll1	tolloid-like 1	0.015
cnn3a	calponin 3, acidic a	0.015
ucp2	uncoupling protein 2	0.015
mmp14a	matrix metalloproteinase 14a (membrane-inserted)	0.015
cldn11b	claudin 11b	0.015
drl	draculin	0.015
klf4a	Kruppel-like transcription factor 4a	0.015
fgfrl1a	fibroblast growth factor receptor-like 1a	0.015
foxj1a	forkhead box J1a	0.015
fzd9b	frizzled homolog 9b	0.015
gdnf	glial cell derived neurotrophic factor	0.015
cyp51	cytochrome P450, family 51	0.015
ets1a	v-ets erythroblastosis virus E26 oncogene homolog 1a	0.014
smad6a	SMAD family member 6a	0.014
vipr1	vasoactive intestinal peptide receptor 1	0.014
tpte	transmembrane phosphatase with tensin homology	0.014
notch3	notch homolog 3	0.014
six4b	sine oculis homeobox homolog 4b	0.014	Mouse
csrp1a	cysteine and glycine-rich protein 1a	0.014
foxl1	forkhead box L1	0.014
tnni1b	troponin I, skeletal, slow b	0.014
epb4.1l4	erythrocyte protein band 4.1-like 4	0.014
cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.014
spon2a	spondin 2a, extracellular matrix protein	0.014
ehd1	EH-domain containing 1	0.014
fgf20a	fibroblast growth factor 20a	0.014
hes6	hairy and enhancer of split 6 (Drosophila)	0.014
tmprss4a	transmembrane protease, serine 4a	0.014
polr2d	polymerase (RNA) II (DNA directed) polypeptide D	0.014
smad9	MAD homolog 9 (Drosophila)	0.014
cobl	cordon-bleu homolog (mouse)	0.014
si:dkey-76b14.4	si:dkey-76b14.4	0.014
lhx5	LIM homeobox 5	0.014
mycb	myelocytomatosis oncogene b	0.014
zgc:111821	zgc:111821	0.014
ca8	carbonic anhydrase VIII	0.014
cdh5	cadherin 5	0.014
stc1l	stanniocalcin 1, like	0.013
or111-7	odorant receptor, family D, subfamily 111, member 7	0.013
lhx1b	LIM homeobox 1b	0.013
fzd10	frizzled homolog 10	0.013
gapdh	glyceraldehyde-3-phosphate dehydrogenase	0.013
atoh1a	atonal homolog 1a	0.013
scin	scinderin	0.013
sgcd	sarcoglycan, delta (dystrophin-associated glycoprotein)	0.013
arl4ab	ADP-ribosylation factor-like 4ab	0.013
zgc:92689	zgc:92689	0.013
gnai2l	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like	0.013
med25	mediator of RNA polymerase II transcription, subunit 25 homolog (yeast)	0.013
tfe3b	transcription factor binding to IGHM enhancer 3b	0.013
eif4g2a	eukaryotic translation initiation factor 4, gamma 2a	0.013
zfpl1	zinc finger protein-like 1	0.013
lss	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)	0.013
fhl	four and a half LIM domains	0.013
im:7151449	im:7151449	0.013
slc14a2	solute carrier family 14 (urea transporter), member 2	0.013
hoxc11a	homeo box C11a	0.013
nkx3.2	NK3 homeobox 2	0.013
ltbp3	latent transforming growth factor beta binding protein 3	0.013
runx2a	runt-related transcription factor 2a	0.013
grnb	granulin b	0.013
vegfab	vascular endothelial growth factor Ab	0.013
tie1	endothelium-specific receptor tyrosine kinase 1	0.012
defbl3	defensin, beta-like 3	0.012
glula	glutamate-ammonia ligase (glutamine synthase) a	0.012
dnaja2	DnaJ (Hsp40) homolog, subfamily A, member 2	0.012
gna11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)	0.012
aplnrb	apelin receptor b	0.012
lmo4b	LIM domain only 4b	0.012
furinb	furin (paired basic amino acid cleaving enzyme) b	0.012
hibadha	3-hydroxyisobutyrate dehydrogenase a	0.012
zeb1	zinc finger E-box binding homeobox 1	0.012
zgc:101761	zgc:101761	0.012
LOC559201	similar to Neuromedin-K receptor (NKR) (Neurokinin B receptor) (NK-3 receptor) (NK-3R) (Tachykinin receptor 3)	0.012
hmx4	H6 family homeobox 4	0.012
kita	kit receptor a	0.012
cxc46	CXC chemokine 46	0.012
LOC100149056	pannexin-3-like	0.012
dmd	dystrophin	0.012
hsd17b3	hydroxysteroid (17-beta) dehydrogenase 3	0.012
ugt1b1	UDP glucuronosyltransferase 1 family, polypeptide B1	0.012
znf622	zinc finger protein 622	0.012
dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.012
cacnb4b	calcium channel, voltage-dependent, beta 4b subunit	0.012
rarga	retinoic acid receptor gamma a	0.012
bmp5	bone morphogenetic protein 5	0.012
pkz	protein kinase containing Z-DNA binding domains	0.012
lamp2	lysosomal membrane glycoprotein 2	0.012
p4ha2	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2	0.012
cldn5b	claudin 5b	0.012
gnai1	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	0.012
zgc:123010	zgc:123010	0.012
wtip	Wilms tumor 1 interacting protein	0.012
mmp14b	matrix metalloproteinase 14b (membrane-inserted)	0.012
ptgs2a	prostaglandin-endoperoxide synthase 2a	0.012
lpp	LIM domain containing preferred translocation partner in lipoma	0.012
angpt2	angiopoietin 2	0.012
cnga2	cyclic nucleotide gated channel alpha 2	0.012
aldh1a3	aldehyde dehydrogenase 1 family, member A3	0.011
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.011
sat1a	spermidine/spermine N1-acetyltransferase 1a	0.011
tmem110l	transmembrane protein 110, like	0.011
smyhc1	slow myosin heavy chain 1	0.011
fgf8a	fibroblast growth factor 8 a	0.011
LOC100332039	ectonucleotide pyrophosphatase/phosphodiesterase family member 2-like	0.011
zgc:66472	zgc:66472	0.011
epas1a	endothelial PAS domain protein 1a	0.011
igfbp1a	insulin-like growth factor binding protein 1a	0.011
itgb1b	integrin, beta 1b	0.011
sp7	Sp7 transcription factor	0.011
mapkapk2a	mitogen-activated protein kinase-activated protein kinase 2a	0.011
keap1b	kelch-like ECH-associated protein 1b	0.011
efna1b	ephrin A1b	0.011
gfer	growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)	0.011
atp1a2a	ATPase, Na+/K+ transporting, alpha 2a polypeptide	0.011
prrx1b	paired related homeobox 1b	0.011
oc90	otoconin 90	0.011
itga2b	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)	0.011
fgf19	fibroblast growth factor 19	0.011
fabp10b	fatty acid binding protein 10b, liver basic	0.011
twist1a	twist1a	0.011
cmlc1	cardiac myosin light chain-1	0.011
il17rd	interleukin 17 receptor D	0.011
erbb3b	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b	0.011
zgc:112355	zgc:112355	0.011
sp5l	Sp5 transcription factor-like	0.011
csrnp1a	cysteine-serine-rich nuclear protein 1a	0.011
ids	iduronate 2-sulfatase	0.011
slco2b1	solute carrier organic anion transporter family, member 2B1	0.011
pygl	phosphorylase, glycogen; liver (Hers disease, glycogen storage disease type VI)	0.011
tfe3a	transcription factor binding to IGHM enhancer 3a	0.011
slc9a8	solute carrier family 9 (sodium/hydrogen exchanger), member 8	0.011
LOC567504	interferon-induced protein with tetratricopeptide repeats 5-like	0.011
rag1	recombination activating gene 1	0.011
six4.3	sine oculis homeobox homolog 4.3	0.011
gnas	GNAS complex locus	0.011
slc17a7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7	0.011
bida	BH3 interacting domain death agonist	0.011
zgc:65979	zgc:65979	0.011
lmbr1l	limb region 1 like	0.011
adipor2	adiponectin receptor 2	0.011
erg	v-ets erythroblastosis virus E26 oncogene like (avian)	0.011
dnajb12	DnaJ (Hsp40) homolog, subfamily B, member 12	0.011
tpbgl	trophoblast glycoprotein-like	0.011
zgc:195154	zgc:195154	0.010
pvrl1a	poliovirus receptor-related 1a	0.010
gsna	gelsolin a	0.010
rps3a	ribosomal protein S3A	0.010
synpo2lb	synaptopodin 2-like b	0.010
gnaia	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a	0.010
LOC567131	calcitonin gene-related peptide type 1 receptor-like	0.010
alpi	alkaline phosphatase, intestinal	0.010
zgc:56272	zgc:56272	0.010
crygm6	crystallin, gamma M6	0.010
aldh2a	aldehyde dehydrogenase 2 family (mitochondrial)a	0.010
zgc:100919	zgc:100919	0.010
sepn1	selenoprotein N, 1	0.010
kiss1ra	KISS1 receptor a	0.010
pnx	posterior neuron-specific homeobox	0.010
mmp9	matrix metalloproteinase 9	0.010
hspb1	heat shock protein, alpha-crystallin-related, 1	0.010
angptl1	angiopoietin-like 1	0.010
tsku	tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)	0.010
kcnh2	potassium voltage-gated channel, subfamily H (eag-related), member 2	0.010
LOC569232	UPF0672 protein CXorf36 homolog	0.010
card9	caspase recruitment domain family, member 9	0.010
vdrb	vitamin D receptor b	0.010
calcrla	calcitonin receptor-like a	0.010
epor	erythropoietin receptor	0.010
prcp	prolylcarboxypeptidase (angiotensinase C)	0.010
jkamp	jnk1/mapk8-associated membrane protein	0.010
olfcd3	olfactory receptor C family, d3	0.010
amh	anti-Mullerian hormone	0.010
smchd1	structural maintenance of chromosomes flexible hinge domain containing 1	0.010
si:ch211-284e13.2	si:ch211-284e13.2	0.010
bbc3	BCL2 binding component 3	0.010
sparc	secreted acidic cysteine rich glycoprotein	0.010