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Danio rerio

14 genes annotated in zebrafish

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mesodermal cell fate commitment

GO:0001710

The cell differentiation process that results in commitment of a cell to become part of the mesoderm.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mesodermal cell fate commitment"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "mesodermal cell fate commitment" (in gray)

Name	Description	Probability	Func Analog Organism
tbx1	T-box 1	0.945
bmp4	bone morphogenetic protein 4	0.859
eya1	eyes absent homolog 1	0.857	Mouse Worm
hnf1ba	HNF1 homeobox Ba	0.815
flh	floating head	0.765
dharma	dharma	0.709
wnt4a	wingless-type MMTV integration site family, member 4a	0.699	Zebrafish
hoxb3a	homeo box B3a	0.655	Zebrafish
gli1	GLI-Kruppel family member 1	0.622
wnt3	wingless-type MMTV integration site family, member 3	0.613	Zebrafish
fgf3	fibroblast growth factor 3	0.549
chd	chordin	0.527
shha	sonic hedgehog a	0.508
pax2a	paired box gene 2a	0.474	Mouse
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.473	Zebrafish
wnt5b	wingless-type MMTV integration site family, member 5b	0.472	Zebrafish
wnt9a	wingless-type MMTV integration site family, member 9A	0.457	Zebrafish
hoxa2b	homeo box A2b	0.441
notch3	notch homolog 3	0.429	Zebrafish
hoxd4a	homeo box D4a	0.428
oep	one-eyed pinhead	0.393
bmp2b	bone morphogenetic protein 2b	0.383
msxc	muscle segment homeobox C	0.376
dlx2a	distal-less homeobox gene 2a	0.356
dkk1b	dickkopf 1b	0.340
tbx18	T-box 18	0.332
ndr2	nodal-related 2	0.310
wnt3a	wingless-type MMTV integration site family, member 3A	0.305	Human Zebrafish Mouse
wnt8b	wingless-type MMTV integration site family, member 8b	0.300	Zebrafish
fgf10a	fibroblast growth factor 10a	0.289
foxi1	forkhead box I1	0.276
her5	hairy-related 5	0.272
six4b	sine oculis homeobox homolog 4b	0.269	Worm
boc	brother of CDO	0.266
foxd5	forkhead box D5	0.253
twist3	twist3	0.251	Worm Fly
vent	ventral expressed homeobox	0.238
hoxa3a	homeo box A3a	0.231	Zebrafish
cdx4	caudal type homeo box transcription factor 4	0.231
dab1a	disabled homolog 1a (Drosophila)	0.230
mib	mind bomb	0.218
rest	RE1-silencing transcription factor	0.218
zic1	zic family member 1 (odd-paired homolog, Drosophila)	0.216
spns2	spinster homolog 2 (Drosophila)	0.211
sox3	SRY-box containing gene 3	0.210
dld	deltaD	0.201
alas2	aminolevulinate, delta-, synthetase 2	0.195
gbx2	gastrulation brain homeo box 2	0.195
slit3	slit (Drosophila) homolog 3	0.193
notch1a	notch homolog 1a	0.190
pax8	paired box gene 8	0.173
ved	ventrally expressed dharma/bozozok antagonist	0.172
wif1	wnt inhibitory factor 1	0.172
tbx5a	T-box 5a	0.169
wnt1	wingless-type MMTV integration site family, member 1	0.166	Zebrafish
hoxa11a	homeo box A11a	0.164
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.162	Mouse
smo	smoothened homolog (Drosophila)	0.160
ephb4b	eph receptor B4b	0.156
cyp26b1	cytochrome P450, family 26, subfamily b, polypeptide 1	0.153
tll1	tolloid-like 1	0.151
epha7	eph receptor A7	0.149
neo1	neogenin 1	0.146
foxb1.2	forkhead box B1.2	0.145
snai1b	snail homolog 1b (Drosophila)	0.139
sox2	SRY-box containing gene 2	0.137
admp	anti-dorsalizing morphogenic protein	0.137
lhx5	LIM homeobox 5	0.133
flot2a	flotillin 2a	0.129
wnt2	wingless-type MMTV integration site family member 2	0.123	Zebrafish
irx5a	iroquois homeobox protein 5a	0.120
pcdh8	protocadherin 8	0.116
tbx16	T-box gene 16	0.115
gata3	GATA-binding protein 3	0.115
hoxc6a	homeo box C6a	0.112
irx1a	iroquois homeobox protein 1, a	0.111
hoxd13a	homeo box D13a	0.109
hoxb2a	homeo box B2a	0.107
hmx4	H6 family homeobox 4	0.102	Worm
mab21l2	mab-21-like 2	0.101
spry2	sprouty homolog 2	0.099
sox21a	SRY-box containing gene 21a	0.096
hhip	hedgehog interacting protein	0.093
bmp7a	bone morphogenetic protein 7a	0.091
six2a	sine oculis-related homeobox 2a	0.090	Mouse
six1b	sine oculis homeobox homolog 1b	0.089
lhx1b	LIM homeobox 1b	0.088
eve1	even-skipped-like1	0.088
wnt10a	wingless-type MMTV integration site family, member 10a	0.088	Zebrafish
plagl2	pleiomorphic adenoma gene-like 2	0.087
hoxd11a	homeo box D11a	0.084
gyltl1b	glycosyltransferase-like 1b	0.084
atoh1a	atonal homolog 1a	0.083
tp63	tumor protein p63	0.082
bmp2a	bone morphogenetic protein 2a	0.081	Zebrafish
fzd10	frizzled homolog 10	0.079
foxn4	forkhead box N4	0.078
foxh1	forkhead box H1	0.076
hoxb1b	homeo box B1b	0.075
hmx3	homeo box (H6 family) 3	0.074	Worm
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.074
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.073	Worm
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.071
tbx6	T-box gene 6	0.071
sox17	SRY-box containing gene 17	0.070	Mouse
znf503	zinc finger protein 503	0.067
nanos3	nanos homolog 3	0.067
nkx2.2a	NK2 transcription factor related 2a	0.064
zfyve26	zinc finger, FYVE domain containing 26	0.063
epb4.1l4	erythrocyte protein band 4.1-like 4	0.061
vox	ventral homeobox	0.061
dbx1a	developing brain homeobox 1a	0.061
gata2a	GATA-binding protein 2a	0.061
sp5l	Sp5 transcription factor-like	0.061
wnt11r	wingless-type MMTV integration site family, member 11, related	0.060	Zebrafish
tbx2b	T-box 2b	0.059
nog2	noggin 2	0.058
wnt7bb	wingless-type MMTV integration site family, member 7Bb	0.057
msxe	muscle segment homeobox E	0.057
runx2b	runt-related transcription factor 2b	0.056
sox32	SRY-box containing gene 32	0.055	Mouse
vangl2	vang-like 2 (van gogh, Drosophila)	0.054
gdf6b	growth differentiation factor 6b	0.053
hoxb6a	homeo box B6a	0.053
nr2f1a	nuclear receptor subfamily 2, group F, member 1a	0.053
si:ch211-173o4.2	si:ch211-173o4.2	0.052
axin1	axin 1	0.051
irx3a	iroquois homeobox protein 3a	0.051
dla	deltaA	0.051
col11a2	collagen type XI alpha-2	0.050
sfrp1a	secreted frizzled-related protein 1a	0.049
sox4b	SRY-box containing gene 4b	0.047
szl	sizzled	0.047
mespb	mesoderm posterior b	0.046	Mouse
hoxb8a	homeo box B8a	0.045
spry1	sprouty homolog 1 (Drosophila)	0.044
hoxa9a	homeo box A9a	0.043
her7	hairy and enhancer of split related-7	0.042
fgfr1a	fibroblast growth factor receptor 1a	0.042	Mouse Fly
nkd1	naked cuticle homolog 1 (Drosophila)	0.042
hoxb4a	homeo box B4a	0.041
meis2.2	myeloid ecotropic viral integration site 2.2	0.040
pdlim7	PDZ and LIM domain 7	0.040
notum3	notum 3	0.040
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.040
gli2a	GLI-Kruppel family member GLI2a	0.040
wnt10b	wingless-type MMTV integration site family, member 10b	0.040	Zebrafish
dlx4b	distal-less homeobox gene 4b	0.040
epha4b	eph receptor A4b	0.039
efnb3b	ephrin B3b	0.039
hoxa13b	homeo box A13b	0.039
sox1a	SRY-box containing gene 1a	0.039
gro2	groucho 2	0.039
mmp2	matrix metalloproteinase 2	0.039
gpc4	glypican 4	0.038
nog1	noggin 1	0.038
cdh2	cadherin 2, neuronal	0.038
gbx1	gastrulation brain homeobox 1	0.037
wnt7aa	wingless-type MMTV integration site family, member 7Aa	0.037	Zebrafish
dbx1b	developing brain homeobox 1b	0.036
lhx2b	LIM homeobox 2b	0.036
chrna2a	cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)	0.036
gata4	GATA-binding protein 4	0.036
pcdh18a	protocadherin 18a	0.035
notch1b	notch homolog 1b	0.035	Zebrafish
fn1	fibronectin 1	0.035
kal1b	Kallmann syndrome 1b sequence	0.035
six4a	sine oculis homeobox homolog 4a	0.035
odz4	odd Oz/ten-m homolog 4	0.034
sema3aa	semaphorin 3aa	0.034
vax2	ventral anterior homeobox 2	0.034
pdzrn3	PDZ domain containing RING finger 3 and PDZ domain containing ring finger 3	0.033
tbx15	T-box 15	0.032
grem2	gremlin 2, cysteine knot superfamily	0.031
pou3f3b	POU class 3 homeobox 3b	0.030
neurod4	neurogenic differentiation 4	0.030
spaw	southpaw	0.030
lama5	laminin, alpha 5	0.030
wnt11	wingless-type MMTV integration site family, member 11	0.029	Zebrafish
foxg1a	forkhead box G1a	0.029
msxb	muscle segment homeobox B	0.029
gli2b	GLI-Kruppel family member GLI2b	0.029
fbln1	fibulin 1	0.029
col8a1a	collagen, type VIII, alpha 1a	0.028
lratb	lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)	0.028
hoxd10a	homeo box D10a	0.028
fgf17	fibroblast growth factor 17	0.028
otx1a	orthodenticle homolog 1a	0.027
hoxa1a	homeo box A1a	0.027
hoxb5a	homeo box B5a	0.027
foxp1b	forkhead box P1b	0.027
sox9b	SRY-box containing gene 9b	0.027
ptprsa	protein tyrosine phosphatase, receptor type, s, a	0.027
vsx1	visual system homeobox 1 homolog, chx10-like	0.026
pou5f1	POU domain, class 5, transcription factor 1	0.026
dlc	deltaC	0.026
elk4	ELK4, ETS-domain protein	0.025
mll	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.025
cobl	cordon-bleu homolog (mouse)	0.025
sox19a	SRY-box containing gene 19a	0.025
jag2	jagged 2	0.025
tnfsf10l3	tumor necrosis factor (ligand) superfamily, member 10 like 3	0.025
pax7a	paired box gene 7a	0.025
ryk	receptor-like tyrosine kinase	0.024
znf703	zinc finger protein 703	0.024
inka1a	induced in neural crest by AP2, 1a	0.024
irx1b	iroquois homeobox protein 1, b	0.024
efna5a	ephrin A5a	0.024
hoxc4a	homeo box C4a	0.024
fzd7a	frizzled homolog 7a	0.024
met	met proto-oncogene (hepatocyte growth factor receptor)	0.023
ptprf	protein tyrosine phosphatase, receptor type, F	0.022
tbx2a	T-box gene 2a	0.022
evx1	even-skipped homeobox 1	0.022	Zebrafish
dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.022
hoxc1a	homeo box C1a	0.021
map2k4a	mitogen-activated protein kinase kinase 4a	0.021
zic2a	zic family member 2 (odd-paired homolog, Drosophila), a	0.021
notch2	notch homolog 2	0.021	Zebrafish
foxd3	forkhead box D3	0.021
tbx20	T-box 20	0.021
wls	wntless homolog (Drosophila)	0.021
msxd	muscle segment homeobox D	0.021
fgfr2	fibroblast growth factor receptor 2	0.021	Fly
tcf7l1a	transcription factor 7-like 1a (T-cell specific, HMG-box)	0.020	Worm
tnfsf10l	tumor necrosis factor (ligand) superfamily, member 10 like	0.020
twist1a	twist1a	0.020	Worm Fly
tnnt2a	troponin T2a, cardiac	0.020
hoxa9b	homeo box A9b	0.020
robo1	roundabout homolog 1	0.020
mafl	v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein L	0.020
cdkn1c	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.019
mespa	mesoderm posterior a	0.019	Mouse
has2	hyaluronan synthase 2	0.019
rnasel1	ribonuclease like 1	0.019
gfra1b	gdnf family receptor alpha 1b	0.019
sall4	sal-like 4 (Drosophila)	0.019
anxa5b	annexin A5b	0.018
pax5	paired box gene 5	0.018
hoxb5b	homeo box B5b	0.018
LOC100000500	sclerostin-like	0.018
eng2b	engrailed 2b	0.018
perp	PERP, TP53 apoptosis effector	0.018
tfap2c	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.018
ism1	isthmin 1	0.018
emx1	empty spiracles homeobox 1	0.018
buc	bucky ball	0.018
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.017	Worm
jag1b	jagged 1b	0.017
ihhb	Indian hedgehog homolog b	0.017
pwp2h	PWP2 periodic tryptophan protein homolog (yeast)	0.017
krt4	keratin 4	0.017
col14a1	collagen, type XIV, alpha 1	0.017
oprm1	opioid receptor, mu 1	0.017
tbx24	T-box 24	0.017
axin2	axin 2 (conductin, axil)	0.017
tmem2	transmembrane protein 2	0.016
rarga	retinoic acid receptor gamma a	0.016
chst11	carbohydrate (chondroitin 4) sulfotransferase 11	0.016
ippk	inositol 1,3,4,5,6-pentakisphosphate 2-kinase	0.016
nrarpb	notch-regulated ankyrin repeat protein b	0.016
six1a	sine oculis homeobox homolog 1a	0.016
sb:cb81	sb:cb81	0.016
dlx3b	distal-less homeobox gene 3b	0.016
apc	adenomatosis polyposis coli	0.016
lhx3	LIM homeobox 3	0.015
brd4	bromodomain containing 4	0.015
zmynd11	zinc finger, MYND domain containing 11	0.015
ntn1a	netrin 1a	0.015
lfng	lunatic fringe homolog	0.015
smad9	MAD homolog 9 (Drosophila)	0.015
meis2.1	myeloid ecotropic viral integration site 2.1	0.015
hey2	hairy/enhancer-of-split related with YRPW motif 2	0.014
ncam1b	neural cell adhesion molecule 1b	0.014
msxa	muscle segment homeobox A	0.014
ntla	no tail a	0.014
gdnf	glial cell derived neurotrophic factor	0.014
tcf7l1b	transcription factor 7-like 1b (T-cell specific, HMG-box)	0.014	Worm
wnt4b	wingless-type MMTV integration site family, member 4b	0.014	Zebrafish
pnx	posterior neuron-specific homeobox	0.014
isl1	islet1	0.014
dazl	daz-like gene	0.014
tfap2a	transcription factor AP-2 alpha	0.014
pou2f1a	POU class 2 homeobox 1a	0.014
dmrt3a	doublesex and mab-3 related transcription factor 3a	0.014
fzd5	frizzled homolog 5	0.014
fgf8b	fibroblast growth factor 8 b	0.014
og9x	OG9 homeobox gene	0.014
crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.013
runx2a	runt-related transcription factor 2a	0.013
ext1a	exostoses (multiple) 1a	0.013
sox11b	SRY-box containing gene 11b	0.013
celsr1a	cadherin EGF LAG seven-pass G-type receptor 1a	0.013
zbtb4	zinc finger and BTB domain containing 4	0.013
epb41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	0.013
zfp36l1b	zinc finger protein 36, C3H type-like 1b	0.013
rbpja	recombination signal binding protein for immunoglobulin kappa J region a	0.013
dzip1	DAZ interacting protein 1	0.013
coe2	coe2	0.013
raraa	retinoic acid receptor, alpha a	0.013
angpt2	angiopoietin 2	0.013
cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.013
rx2	retinal homeobox gene 2	0.013
mesp2	mesoderm posterior 2 homolog (mouse)	0.013
ephb3a	eph receptor B3a	0.012
nkx3.2	NK3 homeobox 2	0.012
msgn1	mesogenin 1	0.012
map2k4b	mitogen-activated protein kinase kinase 4b	0.012
pea3	ETS-domain transcription factor pea3	0.012
olig3	oligodendrocyte transcription factor 3	0.012
wnt16	wingless-type MMTV integration site family, member 16	0.012
ier2	immediate early response 2	0.012
her3	hairy-related 3	0.012
mapk4	mitogen-activated protein kinase 4	0.012
smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.012
egfl6	EGF-like-domain, multiple 6	0.012
sim1a	single-minded homolog 1a (Drosophila)	0.012
tpbgl	trophoblast glycoprotein-like	0.012
ascl1b	achaete-scute complex-like 1b (Drosophila)	0.012
hbbe3	hemoglobin beta embryonic-3	0.012
hoxa4a	homeo box A4a	0.012
ptch1	patched 1	0.012
her6	hairy-related 6	0.012
vsx2	visual system homeobox 2	0.012	Zebrafish
rerea	arginine-glutamic acid dipeptide (RE) repeats a	0.012
lef1	lymphocyte enhancer binding factor 1	0.012	Worm
wnt2ba	wingless-type MMTV integration site family, member 2Ba	0.011	Zebrafish
hoxc13a	homeo box C13a	0.011
wnt7ba	wingless-type MMTV integration site family, member 7Ba	0.011	Zebrafish
lft2	lefty2	0.011
tbpl2	TATA box binding protein like 2	0.011
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.011
dhrs3a	dehydrogenase/reductase (SDR family) member 3a	0.011
sema3h	semaphorin 3h	0.011
bon	bonnie and clyde	0.011
map2k7	mitogen-activated protein kinase kinase 7	0.011
eif4e1b	eukaryotic translation initiation factor 4e 1b	0.011
klf4a	Kruppel-like transcription factor 4a	0.011
onecutl	one cut domain, family member, like	0.011
lamb1a	laminin, beta 1a	0.011
tnfrsfa	tumor necrosis factor receptor superfamily, member a	0.011
pitx3	paired-like homeodomain transcription factor 3	0.011
mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.011
ndr1	nodal-related 1	0.010
hoxc8a	homeo box C8a	0.010
fstl1b	follistatin-like 1b	0.010
loxl2b	lysyl oxidase-like 2b	0.010
nrg2a	neuregulin 2a	0.010
hmx2	H6 family homeobox 2	0.010
rgma	RGM domain family, member A	0.010	Worm
wnt9b	wingless-type MMTV integration site family, member 9B	0.010	Zebrafish
dusp6	dual specificity phosphatase 6	0.010
spon2a	spondin 2a, extracellular matrix protein	0.010
hoxa5a	homeo box A5a	0.010
dcc	deleted in colorectal carcinoma	0.010
lft1	lefty1	0.010
irx4b	iroquois homeobox protein 4b	0.010
vasp	vasodilator-stimulated phosphoprotein	0.010
irx4a	iroquois homeobox protein 4a	0.010
hoxa10b	homeo box A10b	0.010
prdm5	PR domain containing 5	0.010