The network for 'smooth muscle cell migration' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

smooth muscle cell migration

The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism.

Mus musculus
Name Description Probability Func Analog Organism
Ptgs2 prostaglandin-endoperoxide synthase 2 0.961
Bcl2 B-cell leukemia/lymphoma 2 0.946
Vegfa vascular endothelial growth factor A 0.936
Csf1 colony stimulating factor 1 (macrophage) 0.917
Nos3 nitric oxide synthase 3, endothelial cell 0.907
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.872
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.863
Fgfr1 fibroblast growth factor receptor 1 0.684
Itga3 integrin alpha 3 0.654
Nrp1 neuropilin 1 0.649
Fgfr2 fibroblast growth factor receptor 2 0.634
Col1a1 collagen, type I, alpha 1 0.587
Src Rous sarcoma oncogene 0.555
Lrp1 low density lipoprotein receptor-related protein 1 0.551
Tgfb1 transforming growth factor, beta 1 0.544
Lama5 laminin, alpha 5 0.540
Kitl kit ligand 0.506
Ptprb protein tyrosine phosphatase, receptor type, B 0.504
Ilk integrin linked kinase 0.497
Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.448
Slit3 slit homolog 3 (Drosophila) 0.444
Nos1 nitric oxide synthase 1, neuronal 0.442
Pdgfb platelet derived growth factor, B polypeptide 0.409
Hspg2 perlecan (heparan sulfate proteoglycan 2) 0.407
Bcar1 breast cancer anti-estrogen resistance 1 0.374
Ednrb endothelin receptor type B 0.332
Smad3 MAD homolog 3 (Drosophila) 0.330
Robo1 roundabout homolog 1 (Drosophila) 0.328
Sema6d sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 0.312
Gli3 GLI-Kruppel family member GLI3 0.302
Dlg4 discs, large homolog 4 (Drosophila) 0.285
Runx2 runt related transcription factor 2 0.234
Trp53 transformation related protein 53 0.215
Kiss1 KiSS-1 metastasis-suppressor 0.209
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.205
Kit kit oncogene 0.200
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.193
Fzd1 frizzled homolog 1 (Drosophila) 0.190
Pbx1 pre B-cell leukemia transcription factor 1 0.186
Pxn paxillin 0.167
Mef2d myocyte enhancer factor 2D 0.156
Epha4 Eph receptor A4 0.154
Plcg1 phospholipase C, gamma 1 0.147
Plxna1 plexin A1 0.144
Lepr leptin receptor 0.143
Notch2 Notch gene homolog 2 (Drosophila) 0.137
Esr1 estrogen receptor 1 (alpha) 0.132
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.130
Sdc3 syndecan 3 0.119
Bax BCL2-associated X protein 0.117
Notch3 Notch gene homolog 3 (Drosophila) 0.113
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.113
Meox2 mesenchyme homeobox 2 0.113
Sema3f sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.110
Mmp9 matrix metallopeptidase 9 0.103
Prrx1 paired related homeobox 1 0.102
Kdr kinase insert domain protein receptor 0.101
Prlr prolactin receptor 0.098
Plat plasminogen activator, tissue 0.094
Sirpa signal-regulatory protein alpha 0.091
Tbx3 T-box 3 0.088
Cxcl12 chemokine (C-X-C motif) ligand 12 0.083
Rara retinoic acid receptor, alpha 0.083
Vhl von Hippel-Lindau tumor suppressor 0.081
Efnb1 ephrin B1 0.076
Lrp5 low density lipoprotein receptor-related protein 5 0.073
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.070
Bak1 BCL2-antagonist/killer 1 0.070
Flt1 FMS-like tyrosine kinase 1 0.070
Ddr2 discoidin domain receptor family, member 2 0.068
Pparg peroxisome proliferator activated receptor gamma 0.065
Arhgef12 Rho guanine nucleotide exchange factor (GEF) 12 0.064
Wwtr1 WW domain containing transcription regulator 1 0.064
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.064
Robo2 roundabout homolog 2 (Drosophila) 0.063
Nrp2 neuropilin 2 0.061
Sema5a sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.059
Smad6 MAD homolog 6 (Drosophila) 0.059
Bmp4 bone morphogenetic protein 4 0.055
Fgfr3 fibroblast growth factor receptor 3 0.054
Bmp7 bone morphogenetic protein 7 0.054
Ednra endothelin receptor type A 0.054
Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 0.052
Fscn1 fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus) 0.052
Pthlh parathyroid hormone-like peptide 0.051
S1pr3 sphingosine-1-phosphate receptor 3 0.050
Bmp1 bone morphogenetic protein 1 0.049
Vangl2 vang-like 2 (van gogh, Drosophila) 0.049
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.044
Cav1 caveolin 1, caveolae protein 0.043
Mrc2 mannose receptor, C type 2 0.043
Acvr1 activin A receptor, type 1 0.042
Meox1 mesenchyme homeobox 1 0.042
Rarg retinoic acid receptor, gamma 0.042
Bmpr2 bone morphogenic protein receptor, type II (serine/threonine kinase) 0.041
Ret ret proto-oncogene 0.041
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.040
Arid5b AT rich interactive domain 5B (MRF1-like) 0.037
Slc9a3r2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 0.037
Parva parvin, alpha 0.037
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.999
EGFR epidermal growth factor receptor 0.996
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.992
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.921
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.900
BCAR1 breast cancer anti-estrogen resistance 1 0.890
VEGFA vascular endothelial growth factor A 0.888
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.798
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 0.700
CCR5 chemokine (C-C motif) receptor 5 0.686
IGF2R insulin-like growth factor 2 receptor 0.659
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.645
ILK integrin-linked kinase 0.615
C1QA complement component 1, q subcomponent, A chain 0.613
FYN FYN oncogene related to SRC, FGR, YES 0.602
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.548
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.538
NRP1 neuropilin 1 0.527
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.448
NCOR2 nuclear receptor corepressor 2 0.398
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.341
DCN decorin 0.327
MET met proto-oncogene (hepatocyte growth factor receptor) 0.326
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.311
FN1 fibronectin 1 0.294
TM4SF1 transmembrane 4 L six family member 1 0.239
S100B S100 calcium binding protein B 0.238
CDH5 cadherin 5, type 2 (vascular endothelium) 0.230
GAB1 GRB2-associated binding protein 1 0.204
PXN paxillin 0.183
CCR1 chemokine (C-C motif) receptor 1 0.175
PLAU plasminogen activator, urokinase 0.175
TLN1 talin 1 0.173
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.165
IGF1R insulin-like growth factor 1 receptor 0.156
C1QC complement component 1, q subcomponent, C chain 0.153
CCL2 chemokine (C-C motif) ligand 2 0.151
PGF placental growth factor 0.145
PLAT plasminogen activator, tissue 0.141
PDGFC platelet derived growth factor C 0.134
PDGFA platelet-derived growth factor alpha polypeptide 0.131
MAPK8 mitogen-activated protein kinase 8 0.127
ESRRG estrogen-related receptor gamma 0.122
AXL AXL receptor tyrosine kinase 0.118
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.114
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.114
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.105
TIMP3 TIMP metallopeptidase inhibitor 3 0.096
THBS1 thrombospondin 1 0.091
OSMR oncostatin M receptor 0.089
CCL8 chemokine (C-C motif) ligand 8 0.086
JDP2 Jun dimerization protein 2 0.086
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 0.086
CXCL9 chemokine (C-X-C motif) ligand 9 0.084
JAK2 Janus kinase 2 0.082
BCL2L1 BCL2-like 1 0.081
COL1A1 collagen, type I, alpha 1 0.080
IL1B interleukin 1, beta 0.074
CCL13 chemokine (C-C motif) ligand 13 0.070
PPARG peroxisome proliferator-activated receptor gamma 0.069
HSPG2 heparan sulfate proteoglycan 2 0.066
PPARA peroxisome proliferator-activated receptor alpha 0.065
PLAUR plasminogen activator, urokinase receptor 0.065
CXCL12 chemokine (C-X-C motif) ligand 12 0.061
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.058
ATF4 activating transcription factor 4 (tax-responsive enhancer element B67) 0.056
TTR transthyretin 0.053
PTGIS prostaglandin I2 (prostacyclin) synthase 0.053
SYNRG synergin, gamma 0.051
TGFB3 transforming growth factor, beta 3 0.051
KITLG KIT ligand 0.050
INSR insulin receptor 0.050
SPRR2A small proline-rich protein 2A 0.049
LIMS1 LIM and senescent cell antigen-like domains 1 0.047
MAPT microtubule-associated protein tau 0.047
TF transferrin 0.046
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.045
MS4A4A membrane-spanning 4-domains, subfamily A, member 4 0.044
ATF5 activating transcription factor 5 0.044
LDLR low density lipoprotein receptor 0.044
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.044
TGFB1I1 transforming growth factor beta 1 induced transcript 1 0.042
IL8 interleukin 8 0.041
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.041
RABEP1 rabaptin, RAB GTPase binding effector protein 1 0.040
IGF2 insulin-like growth factor 2 (somatomedin A) 0.039
INO80B INO80 complex subunit B 0.039
APP amyloid beta (A4) precursor protein 0.035
CCL4 chemokine (C-C motif) ligand 4 0.035
GRB2 growth factor receptor-bound protein 2 0.034
PLCG1 phospholipase C, gamma 1 0.034
IRS1 insulin receptor substrate 1 0.032
SORT1 sortilin 1 0.031
CAV1 caveolin 1, caveolae protein, 22kDa 0.031
IDE insulin-degrading enzyme 0.029
NOV nephroblastoma overexpressed gene 0.029
SETDB1 SET domain, bifurcated 1 0.028
GAB2 GRB2-associated binding protein 2 0.028
STAB1 stabilin 1 0.028
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.028
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Rattus norvegicus
Name Description Probability Func Analog Organism
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.228
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.201
Mmp10 matrix metallopeptidase 10 0.168
Fcgr3a Fc fragment of IgG, low affinity IIIa, receptor 0.151
Ptafr platelet-activating factor receptor 0.140
Inpp5d inositol polyphosphate-5-phosphatase D 0.139
Col12a1 collagen, type XII, alpha 1 0.133
Smad3 SMAD family member 3 0.109
Mmp3 matrix metallopeptidase 3 0.090
Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.088
Lox lysyl oxidase 0.087
RGD1561143 similar to cell surface receptor FDFACT 0.076
Fosl1 fos-like antigen 1 0.075
Cd4 Cd4 molecule 0.072
Cd38 CD38 molecule 0.071
Elf1 E74-like factor 1 0.068
Ctsj cathepsin J 0.066
Mmp12 matrix metallopeptidase 12 0.062
F2rl1 coagulation factor II (thrombin) receptor-like 1 0.055
Tgfbr3 transforming growth factor, beta receptor III 0.051
Tgfbr2 transforming growth factor, beta receptor II 0.051
RT1-Ba RT1 class II, locus Ba 0.050
Marcks myristoylated alanine rich protein kinase C substrate 0.050
Gal galanin prepropeptide 0.050
Trib1 tribbles homolog 1 (Drosophila) 0.049
Vav1 vav 1 guanine nucleotide exchange factor 0.046
Csn1s1 casein alpha s1 0.045
Chrng cholinergic receptor, nicotinic, gamma 0.044
Il1a interleukin 1 alpha 0.044
Ednrb endothelin receptor type B 0.043
Cybb cytochrome b-245, beta polypeptide 0.042
Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 0.041
Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 0.041
P2ry6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.041
Timp3 TIMP metallopeptidase inhibitor 3 0.041
Plau plasminogen activator, urokinase 0.040
Ar androgen receptor 0.040
Dock8 dedicator of cytokinesis 8 0.040
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.040
Cxcl13 chemokine (C-X-C motif) ligand 13 0.039
Ptprc protein tyrosine phosphatase, receptor type, C 0.039
Lcp2 lymphocyte cytosolic protein 2 0.039
Cd14 CD14 molecule 0.039
Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.039
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.039
Casp1 caspase 1 0.037
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.037
RGD1564327 similar to integrin alpha 8 0.037
Scnn1g sodium channel, nonvoltage-gated 1, gamma 0.036
Slco2b1 solute carrier organic anion transporter family, member 2b1 0.035
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.034
Pld2 phospholipase D2 0.034
Edn1 endothelin 1 0.032
Ugt8 UDP glycosyltransferase 8 0.032
Tacr1 tachykinin receptor 1 0.032
Lfng LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.032
Efna5 ephrin A5 0.031
Pstpip1 proline-serine-threonine phosphatase-interacting protein 1 0.031
Reg3g regenerating islet-derived 3 gamma 0.031
Pqcp polyglutamine-containing protein 0.031
Tead3 TEA domain family member 3 0.031
Bst1 bone marrow stromal cell antigen 1 0.031
LOC304903 similar to Pappalysin-2 precursor (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP-E) 0.030
RGD1304644 similar to RIKEN cDNA 2310046K01 0.030
Wnt5a wingless-type MMTV integration site family, member 5A 0.030
Mmp13 matrix metallopeptidase 13 0.030
Dpep1 dipeptidase 1 (renal) 0.030
Galnt10 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10) 0.029
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.029
Cacnb3 calcium channel, voltage-dependent, beta 3 subunit 0.029
Ednra endothelin receptor type A 0.029
Cd5 Cd5 molecule 0.029
Slc28a3 solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 0.029
Slc22a1 solute carrier family 22 (organic cation transporter), member 1 0.029
Tfec transcription factor EC 0.029
Fcer2 Fc fragment of IgE, low affinity II, receptor for (CD23) 0.029
Slc8a3 solute carrier family 8 (sodium/calcium exchanger), member 3 0.028
Efnb1 ephrin B1 0.028
Ankrd1 ankyrin repeat domain 1 (cardiac muscle) 0.028
Neurl3 neuralized homolog 3 (Drosophila) 0.028
Naaladl1 N-acetylated alpha-linked acidic dipeptidase-like 1 0.028
Cd200r1 CD200 receptor 1 0.028
Cga glycoprotein hormones, alpha polypeptide 0.028
Hivep1 human immunodeficiency virus type I enhancer binding protein 1 0.028
Pla2g2c phospholipase A2, group IIC 0.027
Met met proto-oncogene 0.027
Cd2 Cd2 molecule 0.027
Cish cytokine inducible SH2-containing protein 0.027
Kitlg KIT ligand 0.027
Capn9 calpain 9 0.027
Bid BH3 interacting domain death agonist 0.027
Htr1b 5-hydroxytryptamine (serotonin) receptor 1B 0.026
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.026
Vip vasoactive intestinal peptide 0.026
LOC100360986 mCG1035404-like 0.026
Il1r1 interleukin 1 receptor, type I 0.025
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.025
Ralgds ral guanine nucleotide dissociation stimulator 0.025
Agtr1a angiotensin II receptor, type 1a 0.025
Arhgap10 Rho GTPase activating protein 10 0.025
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism