The network for 'response to hypoxia' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to hypoxia

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.

Mus musculus
Name Description Probability Func Analog Organism
Vegfa vascular endothelial growth factor A 0.997
Nos3 nitric oxide synthase 3, endothelial cell 0.994
Trp53 transformation related protein 53 0.991
Pten phosphatase and tensin homolog 0.990
Tgfbr2 transforming growth factor, beta receptor II 0.930
Ldb3 LIM domain binding 3 0.924
Mmp9 matrix metallopeptidase 9 0.906
Csf1 colony stimulating factor 1 (macrophage) 0.890
Ptgs2 prostaglandin-endoperoxide synthase 2 0.883
Fas Fas (TNF receptor superfamily member 6) 0.849
Cd44 CD44 antigen 0.848
Cav1 caveolin 1, caveolae protein 0.790
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.782
Ece1 endothelin converting enzyme 1 0.731
Notch2 Notch gene homolog 2 (Drosophila) 0.723
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.685
Nos1 nitric oxide synthase 1, neuronal 0.652
Nos2 nitric oxide synthase 2, inducible 0.649
Fbn1 fibrillin 1 0.619
Epas1 endothelial PAS domain protein 1 0.572
Clock circadian locomotor output cycles kaput 0.560
Mdm2 transformed mouse 3T3 cell double minute 2 0.549
Trp73 transformation related protein 73 0.536
Bcl2 B-cell leukemia/lymphoma 2 0.535
Tpi1 triosephosphate isomerase 1 0.529
Lepr leptin receptor 0.528
Ank1 ankyrin 1, erythroid 0.487
Mcl1 myeloid cell leukemia sequence 1 0.483
Kl klotho 0.479
Hif1a hypoxia inducible factor 1, alpha subunit 0.455
Neurl1a neuralized homolog 1A (Drosophila) 0.440
Ren1 renin 1 structural 0.428
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.428
Pparg peroxisome proliferator activated receptor gamma 0.415
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.409
Apoe apolipoprotein E 0.408
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.400
Acvrl1 activin A receptor, type II-like 1 0.398
Ccl2 chemokine (C-C motif) ligand 2 0.389
Egln1 EGL nine homolog 1 (C. elegans) 0.388
Rb1 retinoblastoma 1 0.375
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.367
Skil SKI-like 0.367
Flt1 FMS-like tyrosine kinase 1 0.358
Prkcc protein kinase C, gamma 0.355
Ednra endothelin receptor type A 0.348
Slc10a6 solute carrier family 10 (sodium/bile acid cotransporter family), member 6 0.330
Insr insulin receptor 0.326
Ahr aryl-hydrocarbon receptor 0.317
Tgfb1 transforming growth factor, beta 1 0.316
Il10 interleukin 10 0.299
Prrx1 paired related homeobox 1 0.295
Egfl7 EGF-like domain 7 0.294
Agtr1a angiotensin II receptor, type 1a 0.290
Igh immunoglobulin heavy chain complex 0.282
Stat5a signal transducer and activator of transcription 5A 0.281
Vhl von Hippel-Lindau tumor suppressor 0.281
Tlr4 toll-like receptor 4 0.277
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.274
Lyz2 lysozyme 2 0.259
Gata6 GATA binding protein 6 0.257
Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 0.256
Chrna3 cholinergic receptor, nicotinic, alpha polypeptide 3 0.256
Bax BCL2-associated X protein 0.244
Nf1 neurofibromatosis 1 0.243
Gdnf glial cell line derived neurotrophic factor 0.241
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.241
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.229
Ptgfr prostaglandin F receptor 0.227
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.224
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.215
Canx calnexin 0.211
Kdr kinase insert domain protein receptor 0.211
Chrnb4 cholinergic receptor, nicotinic, beta polypeptide 4 0.207
Chrnb2 cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) 0.202
F2 coagulation factor II 0.202
Wisp2 WNT1 inducible signaling pathway protein 2 0.200
Emx1 empty spiracles homolog 1 (Drosophila) 0.199
Hdac1 histone deacetylase 1 0.198
Gypa glycophorin A 0.197
Gata4 GATA binding protein 4 0.197
Fzd4 frizzled homolog 4 (Drosophila) 0.192
Tgfbr3 transforming growth factor, beta receptor III 0.190
Dll1 delta-like 1 (Drosophila) 0.182
Gnrh1 gonadotropin releasing hormone 1 0.179
Tgfb2 transforming growth factor, beta 2 0.178
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.178
Stat6 signal transducer and activator of transcription 6 0.174
Prkce protein kinase C, epsilon 0.173
Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 0.172
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.168
Egfr epidermal growth factor receptor 0.166
Epor erythropoietin receptor 0.166
Bmp4 bone morphogenetic protein 4 0.158
Meox1 mesenchyme homeobox 1 0.154
Acvr1 activin A receptor, type 1 0.153
Dab1 disabled homolog 1 (Drosophila) 0.151
Tgfbr1 transforming growth factor, beta receptor I 0.150
Fgf8 fibroblast growth factor 8 0.150
Selp selectin, platelet 0.148
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
pitx3 paired-like homeodomain transcription factor 3 0.697
gpia glucose phosphate isomerase a 0.341
ldha lactate dehydrogenase A4 0.257
cx43 connexin 43 0.221
mtmr8 myotubularin related protein 8 0.215
tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.177
nf1a neurofibromin 1a 0.166
vegfaa vascular endothelial growth factor Aa 0.156
prnprs3 prion protein, related sequence 3 0.155
igf1rb insulin-like growth factor 1b receptor 0.151
sgk1 serum/glucocorticoid regulated kinase 1 0.148
osr1 odd-skipped related 1 (Drosophila) 0.146
sema6dl sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like 0.125
entpd3 ectonucleoside triphosphate diphosphohydrolase 3 0.121
th2 tyrosine hydroxylase 2 0.116
igf2b insulin-like growth factor 2b 0.112
bmp4 bone morphogenetic protein 4 0.107
dll4 delta-like 4 (Drosophila) 0.103
rbp4 retinol binding protein 4, plasma 0.103
th tyrosine hydroxylase 0.103
fgfr1a fibroblast growth factor receptor 1a 0.097
nkx2.3 NK2 transcription factor related 3 0.093
LOC100003514 protein kinase C alpha type-like 0.084
cnr1 cannabinoid receptor 1 0.082
ptrfb polymerase I and transcript release factor b 0.081
igf1 insulin-like growth factor 1 0.079
cdh1 cadherin 1, epithelial 0.078
ca8 carbonic anhydrase VIII 0.078
ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.074
npy8ar neuropeptide Y receptor Y8a 0.074
arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.073
cyp24a1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.072
mtor mechanistic target of rapamycin (serine/threonine kinase) 0.071
igfbp1a insulin-like growth factor binding protein 1a 0.067
kdrl kinase insert domain receptor like 0.066
igf2a insulin-like growth factor 2a 0.065
gap43 growth associated protein 43 0.064
aldocb aldolase C, fructose-bisphosphate, b 0.061
mapk6 mitogen-activated protein kinase 6 0.060
LOC799612 prolactin 2 0.059
mcl1b myeloid cell leukemia sequence 1b 0.057
pomca proopiomelanocortin a 0.055
kdr kinase insert domain receptor (a type III receptor tyrosine kinase) 0.054
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.054
id2a inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a 0.053
socs3a suppressor of cytokine signaling 3a 0.053
got2b glutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate aminotransferase 2) 0.052
ptpra protein tyrosine phosphatase, receptor type, A 0.051
cdh4 cadherin 4, retinal 0.051
hspa5 heat shock protein 5 0.049
slc15a2 solute carrier family 15 (H+/peptide transporter), member 2 0.048
fgf20b fibroblast growth factor 20b 0.047
fzd7b frizzled homolog 7b 0.047
odc1 ornithine decarboxylase 1 0.046
bhlhe40 basic helix-loop-helix family, member e40 0.046
ca2 carbonic anhydrase II 0.045
cygb1 cytoglobin 1 0.045
cdc20 cell division cycle 20 homolog 0.045
zgc:165373 zgc:165373 0.045
setd5 SET domain containing 5 0.045
junb jun B proto-oncogene 0.045
nf1b neurofibromin 1b 0.043
ndrg1 N-myc downstream regulated gene 1 0.043
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.043
cpt2 carnitine palmitoyltransferase II 0.042
svil supervillin 0.042
insrb insulin receptor b 0.042
stat3 signal transduction and activation of transcription 3 0.041
eno1 enolase 1, (alpha) 0.040
nr4a2b nuclear receptor subfamily 4, group A, member 2b 0.040
dag1 dystroglycan 1 0.040
efnb2a ephrin B2a 0.040
atp6v1g1 ATPase, H+ transporting, V1 subunit G isoform 1 0.039
mical3 flavoprotein oxidoreductase MICAL3 0.039
hcrt hypocretin (orexin) neuropeptide precursor 0.038
aldoca aldolase C, fructose-bisphosphate, a 0.038
her6 hairy-related 6 0.038
zgc:110775 zgc:110775 0.038
efnb1 ephrin B1 0.037
znf536 zinc finger protein 536 0.037
crabp2a cellular retinoic acid binding protein 2, a 0.036
kif23 kinesin family member 23 0.036
uchl1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.036
grnb granulin b 0.036
tpi1b triosephosphate isomerase 1b 0.036
guca1c guanylate cyclase activator 1C 0.036
pax9 paired box gene 9 0.036
mef2a myocyte enhancer factor 2a 0.034
efna5a ephrin A5a 0.034
pdia4 protein disulfide isomerase associated 4 0.034
slc16a3 solute carrier family 16 (monocarboxylic acid transporters), member 3 0.033
cyp3c1 cytochrome P450, family 3, subfamily c, polypeptide 1 0.032
fos v-fos FBJ murine osteosarcoma viral oncogene homolog 0.032
sfrp5 secreted frizzled-related protein 5 0.032
si:rp71-39b20.7 si:rp71-39b20.7 0.032
srf serum response factor 0.032
etfa electron-transfer-flavoprotein, alpha polypeptide 0.032
neurog3 neurogenin 3 0.031
nrp1a neuropilin 1a 0.031
cxcr4b chemokine (C-X-C motif), receptor 4b 0.031
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Drosophila melanogaster
Name Description Probability Func Analog Organism
EcR Ecdysone receptor 0.935
Fmr1 CG6203 gene product from transcript CG6203-RC 0.804
Hsp70Aa Heat-shock-protein-70Aa 0.575
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.444
Hsp70Ab Heat-shock-protein-70Ab 0.356
E(spl) Enhancer of split 0.347
Hsp68 Heat shock protein 68 0.342
N Notch 0.307
Imp IGF-II mRNA-binding protein 0.295
Gyc76C Guanylyl cyclase at 76C 0.237
HLHm7 E(spl) region transcript m7 0.226
CtBP C-terminal Binding Protein 0.225
Mad Mothers against dpp 0.197
HLHmgamma E(spl) region transcript mgamma 0.174
Egfr Epidermal growth factor receptor 0.169
hh hedgehog 0.158
Tequila CG4821 gene product from transcript CG4821-RE 0.156
hyd hyperplastic discs 0.154
Dsk Drosulfakinin 0.143
Lam Lamin 0.142
Fs(2)Ket Female sterile (2) Ketel 0.139
Src64B Src oncogene at 64B 0.135
HLHmdelta E(spl) region transcript mdelta 0.129
rpr reaper 0.124
CG13253 CG13253 gene product from transcript CG13253-RB 0.123
HLHm3 E(spl) region transcript m3 0.123
Lk6 CG17342 gene product from transcript CG17342-RA 0.118
HLHm5 E(spl) region transcript m5 0.115
Hsp70Bc Heat-shock-protein-70Bc 0.114
Gyc-89Da Guanylyl cyclase at 89Da 0.111
plx pollux 0.105
Mhc Myosin heavy chain 0.103
Hsp26 Heat shock protein 26 0.100
Ork1 Open rectifier K[+] channel 1 0.100
dm diminutive 0.098
ImpL2 Ecdysone-inducible gene L2 0.096
mask multiple ankyrin repeats single KH domain 0.095
InR Insulin-like receptor 0.095
Gyc-89Db Guanylyl cyclase at 89Db 0.092
Hsp27 Heat shock protein 27 0.090
Tbh Tyramine beta hydroxylase 0.089
stumps CG31317 gene product from transcript CG31317-RC 0.086
msps mini spindles 0.082
shakB shaking B 0.081
neuroligin CG13772 gene product from transcript CG13772-RA 0.077
bcd bicoid 0.077
simj simjang 0.073
usp ultraspiracle 0.069
bs blistered 0.067
Mef2 Myocyte enhancer factor 2 0.067
Ca-beta Ca2+-channel-protein-beta-subunit 0.067
sc scute 0.065
Aats-ala Alanyl-tRNA synthetase 0.064
stv starvin 0.063
for foraging 0.063
Pi3K21B CG2699 gene product from transcript CG2699-RA 0.061
Stam Signal transducing adaptor molecule 0.058
ago archipelago 0.057
Tre1 trapped in endoderm-1 0.056
wg wingless 0.055
Yp3 Yolk protein 3 0.054
G-oalpha47A G protein oalpha 47A 0.053
Gr43a Gustatory receptor 43a 0.053
Nmdar1 NMDA receptor 1 0.053
trio CG18214 gene product from transcript CG18214-RA 0.052
Ppn Papilin 0.051
toy twin of eyeless 0.051
ush u-shaped 0.051
kst karst 0.051
ftz-f1 ftz transcription factor 1 0.050
CG8155 CG8155 gene product from transcript CG8155-RA 0.050
Itp-r83A Inositol 1,4,5,-tris-phosphate receptor 0.049
inaC inactivation no afterpotential C 0.049
Hsp22 Heat shock protein 22 0.049
Tao-1 CG14217 gene product from transcript CG14217-RF 0.049
egl egalitarian 0.049
trp transient receptor potential 0.049
Hsp70Bb Heat-shock-protein-70Bb 0.047
malpha E(spl) region transcript malpha 0.047
CG1324 CG1324 gene product from transcript CG1324-RA 0.046
HLHmbeta E(spl) region transcript mbeta 0.046
sbb scribbler 0.046
Cng Cyclic-nucleotide-gated ion channel protein 0.045
Hrb27C Heterogeneous nuclear ribonucleoprotein at 27C 0.045
Gp93 Glycoprotein 93 0.044
Hnf4 Hepatocyte nuclear factor 4 0.043
p53 CG33336 gene product from transcript CG33336-RB 0.043
elav embryonic lethal abnormal vision 0.043
lola longitudinals lacking 0.042
wts warts 0.042
CG15478 CG15478 gene product from transcript CG15478-RA 0.041
bgm bubblegum 0.041
Cg25C Collagen type IV 0.041
Top1 Topoisomerase 1 0.041
mRpL28 mitochondrial ribosomal protein L28 0.040
Scsalpha Succinyl coenzyme A synthetase alpha subunit 0.040
m2 E(spl) region transcript m2 0.039
twi twist 0.039
ppk11 pickpocket 11 0.039
ato atonal 0.039
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Homo sapiens
Name Description Probability Func Analog Organism
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.998
VEGFA vascular endothelial growth factor A 0.983
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.978
BCL2 B-cell CLL/lymphoma 2 0.910
SRF serum response factor (c-fos serum response element-binding transcription factor) 0.903
DAXX death-domain associated protein 0.901
FLNA filamin A, alpha 0.889
EP300 E1A binding protein p300 0.872
TGFB1 transforming growth factor, beta 1 0.870
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.865
TP53 tumor protein p53 0.846
TEK TEK tyrosine kinase, endothelial 0.840
SMAD3 SMAD family member 3 0.816
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.804
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.796
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.789
HSPB8 heat shock 22kDa protein 8 0.788
EPAS1 endothelial PAS domain protein 1 0.763
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.754
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.752
NRP1 neuropilin 1 0.729
ENG endoglin 0.695
PARP1 poly (ADP-ribose) polymerase 1 0.649
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.645
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.641
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.633
PDIA3 protein disulfide isomerase family A, member 3 0.631
HIPK2 homeodomain interacting protein kinase 2 0.583
TOB1 transducer of ERBB2, 1 0.577
UHRF1 ubiquitin-like with PHD and ring finger domains 1 0.536
TSC2 tuberous sclerosis 2 0.535
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.524
HSPB1 heat shock 27kDa protein 1 0.511
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.496
KAT2B K(lysine) acetyltransferase 2B 0.467
LDHA lactate dehydrogenase A 0.451
TACSTD2 tumor-associated calcium signal transducer 2 0.408
ACTN1 actinin, alpha 1 0.407
SUMO1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 0.406
PLAUR plasminogen activator, urokinase receptor 0.395
HDAC1 histone deacetylase 1 0.381
PKM2 pyruvate kinase, muscle 0.371
EGLN3 egl nine homolog 3 (C. elegans) 0.371
EGLN1 egl nine homolog 1 (C. elegans) 0.368
TTR transthyretin 0.367
SNAI1 snail homolog 1 (Drosophila) 0.345
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.343
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.342
CRYAB crystallin, alpha B 0.333
MYH9 myosin, heavy chain 9, non-muscle 0.329
AHR aryl hydrocarbon receptor 0.326
ESR1 estrogen receptor 1 0.320
TSC1 tuberous sclerosis 1 0.311
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.308
HNF4A hepatocyte nuclear factor 4, alpha 0.305
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.304
ACTN4 actinin, alpha 4 0.281
CCL5 chemokine (C-C motif) ligand 5 0.275
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.271
PGK1 phosphoglycerate kinase 1 0.271
CREBBP CREB binding protein 0.265
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.264
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 0.263
JAG1 jagged 1 0.261
RUNX1 runt-related transcription factor 1 0.258
NCL nucleolin 0.254
SMAD7 SMAD family member 7 0.252
BCAR1 breast cancer anti-estrogen resistance 1 0.246
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.241
ABI2 abl-interactor 2 0.231
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.223
STC1 stanniocalcin 1 0.223
NCF1 neutrophil cytosolic factor 1 0.218
VHL von Hippel-Lindau tumor suppressor 0.217
CCT8 chaperonin containing TCP1, subunit 8 (theta) 0.216
IL1RAP interleukin 1 receptor accessory protein 0.214
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.207
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.197
SMAD1 SMAD family member 1 0.196
SIRT1 sirtuin 1 0.196
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.194
THBS1 thrombospondin 1 0.190
ADORA2A adenosine A2a receptor 0.190
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.190
CDK2 cyclin-dependent kinase 2 0.186
FLNB filamin B, beta 0.183
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.182
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.178
MAFG v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) 0.177
PDIA4 protein disulfide isomerase family A, member 4 0.173
ACTB actin, beta 0.170
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.166
BAD BCL2-associated agonist of cell death 0.165
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.164
RANGAP1 Ran GTPase activating protein 1 0.162
GFI1B growth factor independent 1B transcription repressor 0.161
BIRC2 baculoviral IAP repeat containing 2 0.156
NUCB1 nucleobindin 1 0.156
LDHB lactate dehydrogenase B 0.155
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.153
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Rattus norvegicus
Name Description Probability Func Analog Organism
Tbxa2r thromboxane A2 receptor 0.778
Agtr1a angiotensin II receptor, type 1a 0.704
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.663
Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 0.637
Tgfbr2 transforming growth factor, beta receptor II 0.594
Plau plasminogen activator, urokinase 0.585
Hoxa2 homeo box A2 0.578
Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.553
Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 0.528
Cd44 Cd44 molecule 0.499
Hif1a hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.494
S100a9 S100 calcium binding protein A9 0.473
Edn1 endothelin 1 0.463
Akt1 v-akt murine thymoma viral oncogene homolog 1 0.431
Cd4 Cd4 molecule 0.426
Olfml2b olfactomedin-like 2B 0.420
Selp selectin P 0.414
Ghr growth hormone receptor 0.412
Nos3 nitric oxide synthase 3, endothelial cell 0.412
Jak1 Janus kinase 1 0.411
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.403
Anxa2 annexin A2 0.403
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.401
Foxa3 forkhead box A3 0.388
Cxcl10 chemokine (C-X-C motif) ligand 10 0.386
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.384
Dock8 dedicator of cytokinesis 8 0.376
Timp1 TIMP metallopeptidase inhibitor 1 0.370
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.368
Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.366
Ccl4 chemokine (C-C motif) ligand 4 0.366
Shox2 short stature homeobox 2 0.363
Cga glycoprotein hormones, alpha polypeptide 0.363
Vip vasoactive intestinal peptide 0.361
Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 0.360
Ccr5 chemokine (C-C motif) receptor 5 0.353
Gna15 guanine nucleotide binding protein, alpha 15 0.352
B4galt1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.352
Pip4k2b phosphatidylinositol-5-phosphate 4-kinase, type II, beta 0.349
Adra2b adrenergic, alpha-2B-, receptor 0.347
Sell selectin L 0.347
Chrm1 cholinergic receptor, muscarinic 1 0.347
Epas1 endothelial PAS domain protein 1 0.345
Flt1 FMS-related tyrosine kinase 1 0.342
Slc14a2 solute carrier family 14 (urea transporter), member 2 0.335
Sgp158 proline-rich glycoprotein (sgp158) 0.334
Star steroidogenic acute regulatory protein 0.321
Dnase1l3 deoxyribonuclease 1-like 3 0.318
Myh9 myosin, heavy chain 9, non-muscle 0.314
Slc12a1 solute carrier family 12 (sodium/potassium/chloride transporters), member 1 0.310
Guca2a guanylate cyclase activator 2a (guanylin) 0.310
Arpp21 cAMP-regulated phosphoprotein 21 0.307
Anxa1 annexin A1 0.307
Synpo synaptopodin 0.305
Mef2d myocyte enhancer factor 2D 0.304
Mrgprf MAS-related GPR, member F 0.301
Ccr3 chemokine (C-C motif) receptor 3 0.299
Aqp8 aquaporin 8 0.298
Prkcg protein kinase C, gamma 0.293
Htr2b 5-hydroxytryptamine (serotonin) receptor 2B 0.291
Phkg1 phosphorylase kinase, gamma 1 0.288
Adam17 ADAM metallopeptidase domain 17 0.283
Nefh neurofilament, heavy polypeptide 0.281
Apoa5 apolipoprotein A-V 0.279
Eef2 eukaryotic translation elongation factor 2 0.279
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.277
F2rl1 coagulation factor II (thrombin) receptor-like 1 0.274
Smad7 SMAD family member 7 0.272
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 0.269
Prl8a7 prolactin family 8, subfamily a, member 7 0.269
Fn1 fibronectin 1 0.268
Casp2 caspase 2 0.266
Proc protein C 0.266
Stat5b signal transducer and activator of transcription 5B 0.262
Twist2 twist homolog 2 (Drosophila) 0.259
Avp arginine vasopressin 0.258
P2ry6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.257
Neurod2 neurogenic differentiation 2 0.256
Pou3f2 POU class 3 homeobox 2 0.255
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.252
Icam1 intercellular adhesion molecule 1 0.251
Lmna lamin A 0.249
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.248
Uox urate oxidase 0.248
Ascl2 achaete-scute complex homolog 2 (Drosophila) 0.245
Gzmk granzyme K 0.245
Lamc1 laminin, gamma 1 0.244
Myl7 myosin, light chain 7, regulatory 0.243
Gabra6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 0.243
Hck hemopoietic cell kinase 0.240
Il1a interleukin 1 alpha 0.239
Elovl5 ELOVL family member 5, elongation of long chain fatty acids (yeast) 0.239
Prkcd protein kinase C, delta 0.239
Ar androgen receptor 0.239
Accn2 amiloride-sensitive cation channel 2, neuronal 0.238
S100a8 S100 calcium binding protein A8 0.237
S1pr2 sphingosine-1-phosphate receptor 2 0.237
Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.236
Npr3 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) 0.236
Inhbe inhibin beta E 0.234
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
CLB3 Clb3p 0.173
ECM22 Ecm22p 0.070
BUL2 Bul2p 0.057
SNT1 Snt1p 0.056
CDC6 Cdc6p 0.051
SIC1 Sic1p 0.050
YDL241W hypothetical protein 0.045
ZDS1 Zds1p 0.045
YAT1 Yat1p 0.043
CLB1 Clb1p 0.040
CDC20 Cdc20p 0.040
STE2 Ste2p 0.037
STE20 Ste20p 0.036
SIF2 Sif2p 0.036
SSM4 Ssm4p 0.036
CDC24 Cdc24p 0.036
ROM2 Rom2p 0.036
STE5 Ste5p 0.035
ECM30 Ecm30p 0.035
DAK1 Dak1p 0.035
CLN2 Cln2p 0.035
YAT2 Yat2p 0.035
KIN3 Kin3p 0.034
CKS1 Cks1p 0.034
YHB1 Yhb1p 0.033
CLB2 Clb2p 0.033
CLN1 Cln1p 0.032
YPL247C hypothetical protein 0.031
HSL1 Hsl1p 0.031
AFG3 Afg3p 0.031
SWE1 Swe1p 0.030
ADP1 Adp1p 0.030
KAR1 Kar1p 0.029
MCD1 Mcd1p 0.029
YRB1 Yrb1p 0.029
CDC4 Cdc4p 0.029
CMD1 Cmd1p 0.027
NEO1 Neo1p 0.027
IZH4 Izh4p 0.026
GAL83 Gal83p 0.026
CLB4 Clb4p 0.026
TAX4 Tax4p 0.025
MOT2 Mot2p 0.025
ACS1 Acs1p 0.025
YER064C hypothetical protein 0.025
GAD1 Gad1p 0.025
YPL014W hypothetical protein 0.025
PCL9 Pcl9p 0.024
KAP104 Kap104p 0.024
HOR2 Hor2p 0.024
FUN14 Fun14p 0.024
SFH1 Sfh1p 0.024
YOL014W hypothetical protein 0.024
CIT2 Cit2p 0.024
ADE16 Ade16p 0.024
URA8 Ura8p 0.024
STE7 Ste7p 0.024
YMR210W hypothetical protein 0.023
YMR315W hypothetical protein 0.023
ARE2 Are2p 0.023
VPH1 Vph1p 0.023
TGL4 Tgl4p 0.023
YME1 Yme1p 0.023
CRP1 Crp1p 0.023
SAP1 Sap1p 0.023
UBA1 Uba1p 0.023
MKK1 Mkk1p 0.023
MDH2 Mdh2p 0.023
SRD1 Srd1p 0.023
PDH1 Pdh1p 0.023
CRT10 Crt10p 0.023
HOS2 Hos2p 0.022
OCH1 Och1p 0.022
CNB1 Cnb1p 0.022
ARP10 Arp10p 0.022
NTA1 Nta1p 0.022
LAP2 Lap2p 0.022
PKC1 Pkc1p 0.022
ENO2 Eno2p 0.022
DBF20 Dbf20p 0.022
YLR264C-A hypothetical protein 0.022
GSH1 Gsh1p 0.022
YMR155W hypothetical protein 0.022
RAX2 Rax2p 0.022
YPL264C hypothetical protein 0.021
AVT7 Avt7p 0.021
YEH2 Yeh2p 0.021
MCM6 Mcm6p 0.021
PTM1 Ptm1p 0.021
NRG2 Nrg2p 0.021
YIL151C hypothetical protein 0.021
ALD6 Ald6p 0.021
VMA13 Vma13p 0.021
CLG1 Clg1p 0.021
MMT2 Mmt2p 0.021
YGR017W hypothetical protein 0.021
MSA2 Msa2p 0.021
YOL038C-A hypothetical protein 0.021
ENT2 Ent2p 0.021
SAP190 Sap190p 0.021