The network for 'positive regulation of protein kinase activity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of protein kinase activity

Any process that activates or increases the frequency, rate or extent of protein kinase activity.

Mus musculus
Name Description Probability Func Analog Organism
Lepr leptin receptor 0.997
Traf6 TNF receptor-associated factor 6 0.997
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.996
Grb2 growth factor receptor bound protein 2 0.995
Egfr epidermal growth factor receptor 0.991
Efnb2 ephrin B2 0.985
Plcg1 phospholipase C, gamma 1 0.984
Pten phosphatase and tensin homolog 0.977
Cbl Casitas B-lineage lymphoma 0.977
Fgfr2 fibroblast growth factor receptor 2 0.964
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.961
Ctnnb1 catenin (cadherin associated protein), beta 1 0.941
Tnf tumor necrosis factor 0.941
Src Rous sarcoma oncogene 0.940
Mapk8 mitogen-activated protein kinase 8 0.935
Apc adenomatosis polyposis coli 0.931
Ret ret proto-oncogene 0.912
Dab1 disabled homolog 1 (Drosophila) 0.902
Psen1 presenilin 1 0.901
Rac1 RAS-related C3 botulinum substrate 1 0.900
Kit kit oncogene 0.894
Prkce protein kinase C, epsilon 0.878
Inpp5d inositol polyphosphate-5-phosphatase D 0.871
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.868
Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 0.844
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.839
Lyz2 lysozyme 2 0.839
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.836
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.822
Vangl2 vang-like 2 (van gogh, Drosophila) 0.820
Grip1 glutamate receptor interacting protein 1 0.819
Esr1 estrogen receptor 1 (alpha) 0.817
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.813
Gli3 GLI-Kruppel family member GLI3 0.778
Ephb2 Eph receptor B2 0.772
Cd40 CD40 antigen 0.756
Fgfr1 fibroblast growth factor receptor 1 0.742
Dvl2 dishevelled 2, dsh homolog (Drosophila) 0.740
Jag1 jagged 1 0.735
Socs1 suppressor of cytokine signaling 1 0.732
Yap1 yes-associated protein 1 0.725
Apoe apolipoprotein E 0.723
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.721
Tgfa transforming growth factor alpha 0.718
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.716
Csf1 colony stimulating factor 1 (macrophage) 0.707
Wwtr1 WW domain containing transcription regulator 1 0.707
Tgfb2 transforming growth factor, beta 2 0.695
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.689
Irs1 insulin receptor substrate 1 0.689
Tgfbr2 transforming growth factor, beta receptor II 0.682
Pcsk5 proprotein convertase subtilisin/kexin type 5 0.678
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.667
Adam12 a disintegrin and metallopeptidase domain 12 (meltrin alpha) 0.660
Axl AXL receptor tyrosine kinase 0.636
Fras1 Fraser syndrome 1 homolog (human) 0.635
Bmpr2 bone morphogenic protein receptor, type II (serine/threonine kinase) 0.632
Cd44 CD44 antigen 0.630
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.627
Axin1 axin 1 0.622
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.620
Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.619
Efnb1 ephrin B1 0.604
C1qb complement component 1, q subcomponent, beta polypeptide 0.589
Gsk3b glycogen synthase kinase 3 beta 0.586
Cdk5r2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 0.569
Smad3 MAD homolog 3 (Drosophila) 0.567
Epha4 Eph receptor A4 0.566
Fcgr1 Fc receptor, IgG, high affinity I 0.552
Stat5a signal transducer and activator of transcription 5A 0.540
Notch2 Notch gene homolog 2 (Drosophila) 0.538
Fzd4 frizzled homolog 4 (Drosophila) 0.535
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.529
Csf1r colony stimulating factor 1 receptor 0.509
Spry4 sprouty homolog 4 (Drosophila) 0.505
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.504
Acvr2a activin receptor IIA 0.496
Kcns2 K+ voltage-gated channel, subfamily S, 2 0.496
Sykb spleen tyrosine kinase 0.490
Spnb2 spectrin beta 2 0.482
Slc7a2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 0.481
Smad6 MAD homolog 6 (Drosophila) 0.475
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.473
Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit 0.473
Gab1 growth factor receptor bound protein 2-associated protein 1 0.467
Acvr1 activin A receptor, type 1 0.466
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.463
Chrd chordin 0.451
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.448
Ptgs2 prostaglandin-endoperoxide synthase 2 0.446
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.440
Cdc25c cell division cycle 25 homolog C (S. pombe) 0.436
Ephb3 Eph receptor B3 0.433
Wwc2 WW, C2 and coiled-coil domain containing 2 0.433
Thpo thrombopoietin 0.429
Vegfa vascular endothelial growth factor A 0.429
Fbn1 fibrillin 1 0.420
Cx3cr1 chemokine (C-X3-C) receptor 1 0.418
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.413
Bdnf brain derived neurotrophic factor 0.402
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
sur-2 Protein SUR-2 0.211
bar-1 Protein BAR-1 0.117
K08E3.5 Protein K08E3.5 0.110
C11E4.6 Protein C11E4.6 0.074
CELE_Y57G11C.22 Protein Y57G11C.22 0.071
lin-53 Protein LIN-53 0.063
nhr-6 Protein NHR-6 0.061
K10D6.4 Protein K10D6.4 0.061
egl-18 Protein EGL-18 0.054
ldb-1 Protein LDB-1 0.054
mek-2 Protein MEK-2 0.053
rskn-1 Protein RSKN-1 0.053
rpm-1 Protein RPM-1 0.049
mef-2 Protein MEF-2 0.045
mlk-1 Protein MLK-1 0.045
let-60 Protein LET-60 0.045
mpk-1 Protein MPK-1 0.045
lin-25 Protein LIN-25 0.045
chd-7 Protein CHD-7 0.043
tps-1 Protein TPS-1 0.041
igcm-3 Protein IGCM-3 0.041
eps-8 Protein EPS-8 0.039
ina-1 Protein INA-1 0.038
aak-2 Protein AAK-2 0.038
daf-14 Protein DAF-14 0.035
spc-1 Protein SPC-1 0.035
patr-1 Protein PATR-1 0.034
akt-2 Protein AKT-2 0.034
pig-1 Protein PIG-1 0.034
pqn-44 Protein PQN-44 0.033
vav-1 Protein VAV-1 0.033
zyg-11 Protein ZYG-11 0.032
daf-1 Protein DAF-1 0.031
soc-2 Protein SOC-2 0.030
pry-1 Protein PRY-1 0.030
kin-4 Protein KIN-4 0.029
lir-1 Protein LIR-1 0.028
dpy-26 Protein DPY-26 0.027
sel-12 Protein SEL-12 0.026
tam-1 Protein TAM-1 0.026
atg-2 Protein ATG-2 0.026
unc-73 Protein UNC-73 0.025
egl-15 Protein EGL-15 0.023
Y17G7B.20 Protein Y17G7B.20 0.023
par-5 Protein PAR-5 0.023
unc-83 Protein UNC-83 0.023
plc-3 Protein PLC-3 0.022
obr-3 Protein OBR-3 0.022
C05D10.4 Protein C05D10.4 0.022
unc-17 Protein UNC-17 0.021
gsk-3 Protein GSK-3 0.021
unc-18 Protein UNC-18 0.021
F10G8.8 Protein F10G8.8 0.021
hlh-30 Protein HLH-30 0.021
svh-2 Protein SVH-2 0.020
egl-8 Protein EGL-8 0.020
ceh-20 Protein CEH-20 0.020
W08E3.2 Protein W08E3.2 0.019
M02B1.3 Protein M02B1.3 0.019
csnk-1 Protein CSNK-1 0.018
hmp-1 Protein HMP-1 0.018
sli-1 Protein SLI-1 0.018
daf-3 Protein DAF-3 0.018
unc-38 Protein UNC-38 0.018
syd-2 Protein SYD-2 0.018
F54E4.3 Protein F54E4.3 0.018
pkn-1 Protein PKN-1 0.018
zyg-9 Protein ZYG-9 0.017
ttm-5 Protein TTM-5 0.017
rhgf-2 Protein RHGF-2 0.017
eor-1 Protein EOR-1 0.017
nhr-65 Protein NHR-65 0.016
Y56A3A.6 Protein Y56A3A.6 0.016
gei-17 Protein GEI-17 0.016
unc-25 Protein UNC-25 0.016
CELE_Y57A10A.8 Protein Y57A10A.8 0.016
R11A8.7 Protein R11A8.7 0.016
wip-1 Protein WIP-1 0.016
F59E12.1 Protein F59E12.1 0.016
nlg-1 Protein NLG-1 0.015
ksr-1 Protein KSR-1 0.015
tag-256 Protein TAG-256 0.015
unc-10 Protein UNC-10 0.015
mdt-8 Protein MDT-8 0.015
CELE_Y46G5A.8 Protein Y46G5A.8 0.015
Y95B8A.12 Protein Y95B8A.12 0.015
B0336.3 Protein B0336.3 0.015
unc-37 Protein UNC-37 0.015
sem-5 Protein SEM-5 0.015
mes-3 Protein MES-3 0.014
mig-5 Protein MIG-5 0.014
bath-38 Protein BATH-38 0.014
unc-70 Protein UNC-70 0.014
swsn-6 Protein SWSN-6 0.014
sek-1 Protein SEK-1 0.014
mys-1 Protein MYS-1 0.014
fbxa-150 Protein FBXA-150 0.014
ham-1 Protein HAM-1 0.014
cam-1 Protein CAM-1 0.013
alg-1 Protein ALG-1 0.013
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Ras85D Ras oncogene at 85D 0.971
dsh dishevelled 0.852
hep hemipterous 0.736
rl rolled 0.729
ttk tramtrack 0.696
Akt1 CG4006 gene product from transcript CG4006-RA 0.673
bsk basket 0.577
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.497
G-oalpha47A G protein oalpha 47A 0.485
Sara Smad anchor for receptor activation 0.399
kay kayak 0.396
Rho1 CG8416 gene product from transcript CG8416-RB 0.346
mbc myoblast city 0.302
Rac1 CG2248 gene product from transcript CG2248-RA 0.285
Mad Mothers against dpp 0.272
par-1 CG8201 gene product from transcript CG8201-RA 0.271
spi spitz 0.265
Sin3A CG8815 gene product from transcript CG8815-RC 0.248
aop anterior open 0.238
CkIIalpha Casein kinase II alpha subunit 0.218
msn misshapen 0.184
stck steamer duck 0.168
Cip4 CG15015 gene product from transcript CG15015-RA 0.156
dap dacapo 0.156
Su(H) Suppressor of Hairless 0.152
Pkn Protein kinase related to protein kinase N 0.151
X11L CG5675 gene product from transcript CG5675-RB 0.151
HLHmgamma E(spl) region transcript mgamma 0.151
Fhos CG42610 gene product from transcript CG42610-RC 0.146
PTP-ER Protein tyrosine phosphatase-ERK/Enhancer of Ras1 0.141
puc puckered 0.138
rhea CG6831 gene product from transcript CG6831-RA 0.137
CG5794 CG5794 gene product from transcript CG5794-RB 0.124
spas spastin 0.124
chico CG5686 gene product from transcript CG5686-RB 0.123
cta concertina 0.119
tws twins 0.113
sgl sugarless 0.108
babo baboon 0.107
HLHmdelta E(spl) region transcript mdelta 0.098
Cdk4 Cyclin-dependent kinase 4 0.097
HLHm7 E(spl) region transcript m7 0.094
Rac2 CG8556 gene product from transcript CG8556-RA 0.090
Imp IGF-II mRNA-binding protein 0.085
Pten CG5671 gene product from transcript CG5671-RB 0.084
Stat92E Signal-transducer and activator of transcription protein at 92E 0.081
phl pole hole 0.079
HLHmbeta E(spl) region transcript mbeta 0.079
CycE Cyclin E 0.079
vg vestigial 0.077
CG8155 CG8155 gene product from transcript CG8155-RA 0.076
WASp CG1520 gene product from transcript CG1520-RA 0.076
dia diaphanous 0.075
Mcm6 Minichromosome maintenance 6 0.075
jeb jelly belly 0.075
Tom Twin of m4 0.075
pyd polychaetoid 0.073
Liprin-alpha CG11199 gene product from transcript CG11199-RB 0.070
S6k RPS6-p70-protein kinase 0.065
Smg1 CG32743 gene product from transcript CG32743-RA 0.064
yki yorkie 0.062
Dad Daughters against dpp 0.058
sr stripe 0.058
mys myospheroid 0.058
sd scalloped 0.056
dock dreadlocks 0.055
cpb capping protein beta 0.055
lqf liquid facets 0.053
hbs hibris 0.052
Adar Adenosine deaminase acting on RNA 0.052
L Lobe 0.052
Rala Ras-related protein 0.051
Galpha49B G protein alpha49B 0.051
Myo31DF Myosin 31DF 0.049
Atg1 Autophagy-specific gene 1 0.049
E(spl) Enhancer of split 0.049
CtBP C-terminal Binding Protein 0.048
sax saxophone 0.048
l(2)gl lethal (2) giant larvae 0.046
ovo CG6824 gene product from transcript CG6824-RE 0.046
p38b CG7393 gene product from transcript CG7393-RA 0.046
rap retina aberrant in pattern 0.045
btl breathless 0.044
Myb Myb oncogene-like 0.042
drk downstream of receptor kinase 0.042
Hop Hsp70/Hsp90 organizing protein homolog 0.041
HLHm3 E(spl) region transcript m3 0.041
rok Rho-kinase 0.040
Smox Smad on X 0.040
cert ceramide transfer protein 0.039
pyr pyramus 0.039
inaD inactivation no afterpotential D 0.038
malpha E(spl) region transcript malpha 0.038
ecd ecdysoneless 0.038
Mtl Mig-2-like 0.037
Wnk CG7177 gene product from transcript CG7177-RA 0.036
ths thisbe 0.036
Tl Toll 0.035
dm diminutive 0.035
rst roughest 0.035
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Homo sapiens
Name Description Probability Func Analog Organism
EGFR epidermal growth factor receptor 1.000
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 1.000
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 1.000
GRB2 growth factor receptor-bound protein 2 1.000
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.000
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 1.000
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 1.000
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.000
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.999
TRAF6 TNF receptor-associated factor 6 0.999
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.999
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.998
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.996
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.995
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.995
LRRK2 leucine-rich repeat kinase 2 0.995
CAV1 caveolin 1, caveolae protein, 22kDa 0.994
UBC ubiquitin C 0.992
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.991
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.989
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.988
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.988
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.986
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.984
FGFR1 fibroblast growth factor receptor 1 0.983
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.982
FGFR2 fibroblast growth factor receptor 2 0.981
FN1 fibronectin 1 0.976
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.975
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.975
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.974
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.972
BBS10 Bardet-Biedl syndrome 10 0.969
APP amyloid beta (A4) precursor protein 0.961
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.954
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.951
DLG1 discs, large homolog 1 (Drosophila) 0.949
TOLLIP toll interacting protein 0.946
CDC37 cell division cycle 37 homolog (S. cerevisiae) 0.944
IRAK2 interleukin-1 receptor-associated kinase 2 0.943
ENG endoglin 0.942
C1QA complement component 1, q subcomponent, A chain 0.937
TGFB1 transforming growth factor, beta 1 0.935
TEK TEK tyrosine kinase, endothelial 0.934
AXL AXL receptor tyrosine kinase 0.928
WASL Wiskott-Aldrich syndrome-like 0.925
TRAF2 TNF receptor-associated factor 2 0.923
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.921
CDK2 cyclin-dependent kinase 2 0.920
CCNE1 cyclin E1 0.912
TRAF1 TNF receptor-associated factor 1 0.908
PDPK1 3-phosphoinositide dependent protein kinase-1 0.904
SMN1 survival of motor neuron 1, telomeric 0.903
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.902
SYK spleen tyrosine kinase 0.898
RB1 retinoblastoma 1 0.896
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.892
IGF1R insulin-like growth factor 1 receptor 0.891
STK11 serine/threonine kinase 11 0.891
ADAM15 ADAM metallopeptidase domain 15 0.890
NCF2 neutrophil cytosolic factor 2 0.887
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.887
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.887
CCL2 chemokine (C-C motif) ligand 2 0.884
CDK14 cyclin-dependent kinase 14 0.882
CSNK1E casein kinase 1, epsilon 0.880
PLCG1 phospholipase C, gamma 1 0.880
FGF1 fibroblast growth factor 1 (acidic) 0.868
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.861
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.857
TNK2 tyrosine kinase, non-receptor, 2 0.857
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.853
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.853
NCF1 neutrophil cytosolic factor 1 0.850
MAPK14 mitogen-activated protein kinase 14 0.848
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.839
TRAF3 TNF receptor-associated factor 3 0.839
IL1R1 interleukin 1 receptor, type I 0.835
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 0.835
SQSTM1 sequestosome 1 0.833
NRP1 neuropilin 1 0.820
PSG9 pregnancy specific beta-1-glycoprotein 9 0.813
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 0.811
PDCD6IP programmed cell death 6 interacting protein 0.809
TRAF5 TNF receptor-associated factor 5 0.806
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.805
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.792
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 0.788
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.783
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.769
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.758
BMPR1A bone morphogenetic protein receptor, type IA 0.758
BCAR1 breast cancer anti-estrogen resistance 1 0.757
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.755
GH1 growth hormone 1 0.755
MET met proto-oncogene (hepatocyte growth factor receptor) 0.747
MAP3K14 mitogen-activated protein kinase kinase kinase 14 0.742
JAK2 Janus kinase 2 0.737
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.733
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Rattus norvegicus
Name Description Probability Func Analog Organism
Agtr1a angiotensin II receptor, type 1a 0.386
Cd38 CD38 molecule 0.342
Fgfr2 fibroblast growth factor receptor 2 0.311
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.307
Inpp5d inositol polyphosphate-5-phosphatase D 0.262
Gria1 glutamate receptor, ionotropic, AMPA 1 0.251
Cd4 Cd4 molecule 0.243
Jak2 Janus kinase 2 0.209
Oprm1 opioid receptor, mu 1 0.191
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.181
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.159
Smad3 SMAD family member 3 0.158
Fgfr1 Fibroblast growth factor receptor 1 0.156
Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 0.155
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.149
Mapk3 mitogen activated protein kinase 3 0.147
Tacr1 tachykinin receptor 1 0.141
Plau plasminogen activator, urokinase 0.139
Vav1 vav 1 guanine nucleotide exchange factor 0.133
Sirpa signal-regulatory protein alpha 0.133
Eif4h eukaryotic translation initiation factor 4H 0.130
Ptpn7 protein tyrosine phosphatase, non-receptor type 7 0.129
Syt8 synaptotagmin VIII 0.129
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.127
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.120
Unc5b unc-5 homolog B (C. elegans) 0.116
Adarb2 adenosine deaminase, RNA-specific, B2 0.116
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.112
Mapk1 mitogen activated protein kinase 1 0.111
Flt1 FMS-related tyrosine kinase 1 0.110
Lepr leptin receptor 0.109
Nrg1 neuregulin 1 0.109
Fgf5 fibroblast growth factor 5 0.107
Sox17 SRY (sex determining region Y)-box 17 0.107
Clic4 chloride intracellular channel 4 0.106
Prp15 proline-rich protein 15 0.105
Ptafr platelet-activating factor receptor 0.101
Cx3cr1 chemokine (C-X3-C motif) receptor 1 0.095
Hpcal4 hippocalcin-like 4 0.093
Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 0.092
Smad7 SMAD family member 7 0.091
Npy5r neuropeptide Y receptor Y5 0.088
Cxcr4 chemokine (C-X-C motif) receptor 4 0.087
Ptk2b PTK2B protein tyrosine kinase 2 beta 0.087
RGD1564664 similar to LOC387763 protein 0.086
Slc9a1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 0.086
Elf1 E74-like factor 1 0.085
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.084
Mpeg1 macrophage expressed 1 0.084
Cd37 CD37 molecule 0.084
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.084
Nckap1 NCK-associated protein 1 0.083
Pde5a phosphodiesterase 5A, cGMP-specific 0.082
Ube2d4 ubiquitin-conjugating enzyme E2D 4 0.082
Trhr thyrotropin releasing hormone receptor 0.082
Bcan brevican 0.082
Acr acrosin 0.081
Il7r interleukin 7 receptor 0.081
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.080
Slc5a7 solute carrier family 5 (choline transporter), member 7 0.080
Rgs14 regulator of G-protein signaling 14 0.079
Marcks myristoylated alanine rich protein kinase C substrate 0.079
Olr1278 olfactory receptor 1278 0.078
Ccr5 chemokine (C-C motif) receptor 5 0.078
Grm7 glutamate receptor, metabotropic 7 0.077
LOC100365904 hypothetical protein LOC100365904 0.077
Gja1 gap junction protein, alpha 1 0.077
Hfe hemochromatosis 0.077
Mapk14 mitogen activated protein kinase 14 0.076
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.075
Ednrb endothelin receptor type B 0.075
Accn2 amiloride-sensitive cation channel 2, neuronal 0.074
Grb2 growth factor receptor bound protein 2 0.074
Ptprc protein tyrosine phosphatase, receptor type, C 0.074
Ccnd1 cyclin D1 0.073
Stk11 serine/threonine kinase 11 0.073
Cmklr1 chemokine-like receptor 1 0.072
Kcna3 potassium voltage-gated channel, shaker-related subfamily, member 3 0.072
Cox11 COX11 homolog, cytochrome c oxidase assembly protein (yeast) 0.072
Dock8 dedicator of cytokinesis 8 0.071
Sstr5 somatostatin receptor 5 0.071
Calcrl calcitonin receptor-like 0.071
Homer1 homer homolog 1 (Drosophila) 0.070
Insrr insulin receptor-related receptor 0.070
Ncan neurocan 0.069
Adam17 ADAM metallopeptidase domain 17 0.068
Insr insulin receptor 0.067
Itpkb inositol 1,4,5-trisphosphate 3-kinase B 0.066
Hspa8 heat shock protein 8 0.066
Tgfbr2 transforming growth factor, beta receptor II 0.065
Epas1 endothelial PAS domain protein 1 0.065
Egfr epidermal growth factor receptor 0.064
Cfp complement factor properdin 0.064
Olr1500 olfactory receptor 1500 0.064
Kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.063
Robo1 roundabout homolog 1 (Drosophila) 0.063
Samsn1 SAM domain, SH3 domain and nuclear localization signals, 1 0.063
Prkcd protein kinase C, delta 0.063
Foxj1 forkhead box J1 0.063
Nog noggin 0.062
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
PBS2 Pbs2p 0.887
SSK2 Ssk2p 0.764
CDC12 Cdc12p 0.698
SSK1 Ssk1p 0.586
NBP2 Nbp2p 0.321
SIP1 Sip1p 0.296
CDC10 Cdc10p 0.206
GAL83 Gal83p 0.203
HSL1 Hsl1p 0.168
CDC24 Cdc24p 0.157
PAM1 Pam1p 0.157
STE4 Ste4p 0.138
SNF1 Snf1p 0.118
MSG5 Msg5p 0.111
SSK22 Ssk22p 0.104
DBF2 Dbf2p 0.099
STE11 Ste11p 0.093
VPS64 Vps64p 0.092
STI1 Sti1p 0.091
ROM2 Rom2p 0.090
STE7 Ste7p 0.090
BCK1 Bck1p 0.087
BEM3 Bem3p 0.086
RPP2A Rpp2ap 0.083
STE5 Ste5p 0.071
RPP1B Rpp1bp 0.069
BMH1 Bmh1p 0.065
PKH1 Pkh1p 0.059
CDC55 Cdc55p 0.058
MKS1 Mks1p 0.054
RPN14 Rpn14p 0.050
SCJ1 Scj1p 0.048
TOR1 Tor1p 0.047
TRA1 Tra1p 0.044
STE2 Ste2p 0.043
BCK2 Bck2p 0.041
MKK1 Mkk1p 0.041
AHP1 Ahp1p 0.035
CDC4 Cdc4p 0.035
DIA2 Dia2p 0.034
GIC1 Gic1p 0.033
FAR1 Far1p 0.033
RPN2 Rpn2p 0.032
RGD1 Rgd1p 0.032
GPH1 Gph1p 0.031
LAP4 Lap4p 0.030
IRA1 Ira1p 0.030
MYO5 Myo5p 0.030
GIN4 Gin4p 0.029
CDC53 Cdc53p 0.029
HYP2 Hyp2p 0.028
JEM1 Jem1p 0.027
TCO89 Tco89p 0.026
CDC11 Cdc11p 0.026
SAK1 Sak1p 0.026
OSH2 Osh2p 0.026
KCC4 Kcc4p 0.025
MDS3 Mds3p 0.025
PRS2 Prs2p 0.024
CLA4 Cla4p 0.024
HAL5 Hal5p 0.024
AHA1 Aha1p 0.023
PIL1 Pil1p 0.023
ATG29 Atg29p 0.023
TOR2 Tor2p 0.023
IQG1 Iqg1p 0.022
NAB6 Nab6p 0.022
TMA19 Tma19p 0.021
CLB3 Clb3p 0.021
VPS70 Vps70p 0.021
RPS29B Rps29bp 0.020
CDC6 Cdc6p 0.020
CDC3 Cdc3p 0.020
COT1 Cot1p 0.019
NEM1 Nem1p 0.019
MCM4 Mcm4p 0.019
RPP2B Rpp2bp 0.019
SIL1 Sil1p 0.018
BCY1 Bcy1p 0.018
SIP2 Sip2p 0.018
YGL242C hypothetical protein 0.018
NAP1 Nap1p 0.018
BBP1 Bbp1p 0.018
SEC53 Sec53p 0.017
ERO1 Ero1p 0.016
CCW12 Ccw12p 0.016
YGR126W hypothetical protein 0.016
YOL014W hypothetical protein 0.016
MRC1 Mrc1p 0.016
ROD1 Rod1p 0.015
RPL23A Rpl23ap 0.015
BFR1 Bfr1p 0.015
EDE1 Ede1p 0.015
UFO1 Ufo1p 0.015
AXL2 Axl2p 0.015
SMP1 Smp1p 0.015
RGC1 Rgc1p 0.014
SPC29 Spc29p 0.014
YKR011C hypothetical protein 0.014
SIC1 Sic1p 0.014