Process View
The network for 'transforming growth factor beta receptor signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Tgfbr2 | transforming growth factor, beta receptor II | 1.000 | |
Nodal | nodal | 0.995 | |
Smad6 | MAD homolog 6 (Drosophila) | 0.984 | |
Smad4 | MAD homolog 4 (Drosophila) | 0.980 | |
Lox | lysyl oxidase | 0.977 | |
Smad3 | MAD homolog 3 (Drosophila) | 0.977 | |
Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.974 | |
Smad7 | MAD homolog 7 (Drosophila) | 0.961 | |
Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.927 | |
Tgfbr1 | transforming growth factor, beta receptor I | 0.898 | |
Gpc3 | glypican 3 | 0.862 | |
Tgfb2 | transforming growth factor, beta 2 | 0.855 | |
Map3k7 | mitogen-activated protein kinase kinase kinase 7 | 0.851 | |
Skil | SKI-like | 0.841 | |
Thbs1 | thrombospondin 1 | 0.839 | |
Bmp1 | bone morphogenetic protein 1 | 0.828 | |
Bgn | biglycan | 0.805 | |
Mstn | myostatin | 0.801 | |
Apc | adenomatosis polyposis coli | 0.783 | |
Lum | lumican | 0.778 | |
Acvr1 | activin A receptor, type 1 | 0.774 | |
Axin1 | axin 1 | 0.767 | |
Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.764 | |
Col1a1 | collagen, type I, alpha 1 | 0.748 | |
Tgfb1 | transforming growth factor, beta 1 | 0.735 | |
Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.735 | |
Csf1 | colony stimulating factor 1 (macrophage) | 0.733 | |
Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.726 | |
Lep | leptin | 0.711 | |
Pkd2 | polycystic kidney disease 2 | 0.698 | |
Mmp2 | matrix metallopeptidase 2 | 0.689 | |
Trp53 | transformation related protein 53 | 0.637 | |
Bmp4 | bone morphogenetic protein 4 | 0.607 | |
Fgfr2 | fibroblast growth factor receptor 2 | 0.561 | |
Itgb3 | integrin beta 3 | 0.553 | |
Jun | Jun oncogene | 0.538 | |
Fgfr1 | fibroblast growth factor receptor 1 | 0.529 | |
Smo | smoothened homolog (Drosophila) | 0.529 | |
Fst | follistatin | 0.527 | |
Fgf8 | fibroblast growth factor 8 | 0.504 | |
Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.481 | |
Col5a1 | collagen, type V, alpha 1 | 0.466 | |
Pgr | progesterone receptor | 0.466 | |
Nf1 | neurofibromatosis 1 | 0.433 | |
Rarg | retinoic acid receptor, gamma | 0.428 | |
Wnt4 | wingless-related MMTV integration site 4 | 0.423 | |
Emp2 | epithelial membrane protein 2 | 0.422 | |
Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.418 | |
Zfp651 | zinc finger protein 651 | 0.406 | |
Mmp9 | matrix metallopeptidase 9 | 0.397 | |
Bmpr2 | bone morphogenic protein receptor, type II (serine/threonine kinase) | 0.396 | |
Bmp7 | bone morphogenetic protein 7 | 0.392 | |
Gas1 | growth arrest specific 1 | 0.383 | |
Smad1 | MAD homolog 1 (Drosophila) | 0.381 | |
Apoe | apolipoprotein E | 0.379 | |
Scara3 | scavenger receptor class A, member 3 | 0.364 | |
Ltbp1 | latent transforming growth factor beta binding protein 1 | 0.364 | |
Atf2 | activating transcription factor 2 | 0.360 | |
Aebp1 | AE binding protein 1 | 0.358 | |
Tbx1 | T-box 1 | 0.358 | |
Trp63 | transformation related protein 63 | 0.356 | |
Cyr61 | cysteine rich protein 61 | 0.356 | |
Sulf2 | sulfatase 2 | 0.347 | |
Fbln2 | fibulin 2 | 0.347 | |
Timp2 | tissue inhibitor of metalloproteinase 2 | 0.345 | |
Col12a1 | collagen, type XII, alpha 1 | 0.343 | |
Dlg1 | discs, large homolog 1 (Drosophila) | 0.343 | |
Foxc1 | forkhead box C1 | 0.341 | |
Cul3 | cullin 3 | 0.338 | |
Vcl | vinculin | 0.334 | |
Smad2 | MAD homolog 2 (Drosophila) | 0.325 | |
Pten | phosphatase and tensin homolog | 0.316 | |
Col1a2 | collagen, type I, alpha 2 | 0.314 | |
Foxf2 | forkhead box F2 | 0.312 | |
Adam19 | a disintegrin and metallopeptidase domain 19 (meltrin beta) | 0.312 | |
Sox4 | SRY-box containing gene 4 | 0.309 | |
Vegfa | vascular endothelial growth factor A | 0.308 | |
Fgf5 | fibroblast growth factor 5 | 0.300 | |
Lhx1 | LIM homeobox protein 1 | 0.298 | |
Inhba | inhibin beta-A | 0.296 | |
Prrx2 | paired related homeobox 2 | 0.289 | |
Dact1 | dapper homolog 1, antagonist of beta-catenin (xenopus) | 0.287 | |
Islr | immunoglobulin superfamily containing leucine-rich repeat | 0.284 | |
C1qtnf1 | C1q and tumor necrosis factor related protein 1 | 0.282 | |
Efna4 | ephrin A4 | 0.280 | |
Rarb | retinoic acid receptor, beta | 0.280 | |
Spnb2 | spectrin beta 2 | 0.277 | |
Fgf10 | fibroblast growth factor 10 | 0.274 | |
Gsk3b | glycogen synthase kinase 3 beta | 0.273 | |
Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.270 | |
Fzd2 | frizzled homolog 2 (Drosophila) | 0.270 | |
Pax2 | paired box gene 2 | 0.270 | |
Cx3cr1 | chemokine (C-X3-C) receptor 1 | 0.268 | |
Flna | filamin, alpha | 0.267 | |
Loxl1 | lysyl oxidase-like 1 | 0.264 | |
Atp7a | ATPase, Cu++ transporting, alpha polypeptide | 0.263 | |
Plin1 | perilipin 1 | 0.263 | |
Fzd1 | frizzled homolog 1 (Drosophila) | 0.257 | |
Ephb2 | Eph receptor B2 | 0.255 | |
Cdkn2a | cyclin-dependent kinase inhibitor 2A | 0.249 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
daf-11 | Protein DAF-11 | 0.396 | |
daf-1 | Protein DAF-1 | 0.151 | |
osm-3 | Protein OSM-3 | 0.069 | |
vab-3 | Protein VAB-3 | 0.068 | |
unc-9 | Protein UNC-9 | 0.063 | |
cat-1 | Protein CAT-1 | 0.061 | |
pqn-62 | Protein PQN-62 | 0.039 | |
lin-25 | Protein LIN-25 | 0.036 | |
pkg-1 | Protein PKG-1 | 0.035 | |
lin-1 | Protein LIN-1 | 0.034 | |
egl-18 | Protein EGL-18 | 0.032 | |
egl-8 | Protein EGL-8 | 0.031 | |
sma-6 | Protein SMA-6 | 0.029 | |
vab-8 | Protein VAB-8 | 0.028 | |
tag-320 | Protein TAG-320 | 0.028 | |
tax-4 | Protein TAX-4 | 0.025 | |
hlh-30 | Protein HLH-30 | 0.025 | |
nhr-97 | Protein NHR-97 | 0.023 | |
F13H6.1 | Protein F13H6.1 | 0.022 | |
olrn-1 | Protein OLRN-1 | 0.021 | |
mab-31 | Protein MAB-31 | 0.019 | |
osm-5 | Protein OSM-5 | 0.018 | |
daf-12 | Protein DAF-12 | 0.018 | |
pat-3 | Protein PAT-3 | 0.017 | |
odr-3 | Protein ODR-3 | 0.016 | |
daf-4 | Protein DAF-4 | 0.015 | |
osm-6 | Protein OSM-6 | 0.015 | |
dlk-1 | Protein DLK-1 | 0.015 | |
nlp-8 | Protein NLP-8 | 0.014 | |
abl-1 | Protein ABL-1 | 0.014 | |
daf-14 | Protein DAF-14 | 0.014 | |
lin-59 | Protein LIN-59 | 0.013 | |
unc-112 | Protein UNC-112 | 0.013 | |
daf-2 | Protein DAF-2 | 0.013 | |
unc-104 | Protein UNC-104 | 0.012 | |
inx-4 | Protein INX-4 | 0.012 | |
vab-19 | Protein VAB-19 | 0.011 | |
inx-2 | Protein INX-2 | 0.011 | |
pry-1 | Protein PRY-1 | 0.011 | |
unc-73 | Protein UNC-73 | 0.011 | |
C14B9.2 | Protein C14B9.2 | 0.011 | |
tax-6 | Protein TAX-6 | 0.011 | |
sor-3 | Protein SOR-3 | 0.011 | |
daf-7 | Protein DAF-7 | 0.011 | |
unc-7 | Protein UNC-7 | 0.010 | |
cat-4 | Protein CAT-4 | 0.010 | |
zyg-8 | Protein ZYG-8 | 0.010 | |
daf-10 | Protein DAF-10 | 0.010 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
wnt11r | wingless-type MMTV integration site family, member 11, related | 0.025 | |
bmpr1aa | bone morphogenetic protein receptor, type 1aa | 0.023 | |
ephb4b | eph receptor B4b | 0.023 | |
matn4 | matrilin 4 | 0.022 | |
tgfb2 | transforming growth factor, beta 2 | 0.022 | |
rbfox2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.022 | |
tcf12 | transcription factor 12 | 0.021 | |
si:dkeyp-50f5.1 | si:dkeyp-50f5.1 | 0.021 | |
plcg1 | phospholipase C, gamma 1 | 0.019 | |
twist3 | twist3 | 0.019 | |
cdon | cell adhesion molecule-related/down-regulated by oncogenes | 0.018 | |
hs6st2 | heparan sulfate 6-O-sulfotransferase 2 | 0.018 | |
ctgf | connective tissue growth factor | 0.016 | |
ahr2 | aryl hydrocarbon receptor 2 | 0.016 | |
plp1a | proteolipid protein 1a | 0.015 | |
gli2a | GLI-Kruppel family member GLI2a | 0.013 | |
robo1 | roundabout homolog 1 | 0.013 | |
si:ch211-173o4.2 | si:ch211-173o4.2 | 0.013 | |
bglap | bone gamma-carboxyglutamate (gla) protein | 0.013 | |
oep | one-eyed pinhead | 0.013 | |
sulf1 | sulfatase 1 | 0.012 | |
yes1 | v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 | 0.012 | |
wnt11 | wingless-type MMTV integration site family, member 11 | 0.012 | |
bmp2a | bone morphogenetic protein 2a | 0.012 | |
gadd45bb | growth arrest and DNA-damage-inducible, beta b | 0.012 | |
szl | sizzled | 0.012 | |
tp53 | tumor protein p53 | 0.011 | |
sox17 | SRY-box containing gene 17 | 0.011 | |
vgll4l | vestigial like 4 like | 0.011 | |
sdc2 | syndecan 2 | 0.011 | |
zgc:112211 | zgc:112211 | 0.010 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Mad | Mothers against dpp | 0.998 | |
kay | kayak | 0.957 | |
shn | schnurri | 0.949 | |
ci | cubitus interruptus | 0.814 | |
babo | baboon | 0.686 | |
Dad | Daughters against dpp | 0.570 | |
tkv | thickveins | 0.532 | |
krz | kurtz | 0.257 | |
rl | rolled | 0.243 | |
CG11347 | CG11347 gene product from transcript CG11347-RE | 0.202 | |
Akt1 | CG4006 gene product from transcript CG4006-RA | 0.191 | |
Stat92E | Signal-transducer and activator of transcription protein at 92E | 0.188 | |
usp | ultraspiracle | 0.186 | |
sog | short gastrulation | 0.177 | |
Nrx-IV | Neurexin IV | 0.162 | |
mys | myospheroid | 0.156 | |
Pi3K92E | CG4141 gene product from transcript CG4141-RB | 0.154 | |
Sara | Smad anchor for receptor activation | 0.149 | |
gro | groucho | 0.120 | |
puc | puckered | 0.101 | |
Egfr | Epidermal growth factor receptor | 0.099 | |
gbb | glass bottom boat | 0.096 | |
Plc21C | Phospholipase C at 21C | 0.093 | |
Eip93F | CG18389 gene product from transcript CG18389-RB | 0.086 | |
alpha-Adaptin | CG4260 gene product from transcript CG4260-RA | 0.082 | |
ex | expanded | 0.081 | |
put | punt | 0.070 | |
pan | pangolin | 0.063 | |
zip | zipper | 0.062 | |
neuroligin | CG13772 gene product from transcript CG13772-RA | 0.061 | |
hipk | homeodomain interacting protein kinase | 0.056 | |
Rho1 | CG8416 gene product from transcript CG8416-RB | 0.055 | |
CG31224 | CG31224 gene product from transcript CG31224-RA | 0.054 | |
ics | icarus | 0.052 | |
ab | abrupt | 0.052 | |
scb | scab | 0.052 | |
h | hairy | 0.049 | |
p53 | CG33336 gene product from transcript CG33336-RB | 0.048 | |
coro | CG9446 gene product from transcript CG9446-RC | 0.048 | |
l(2)gl | lethal (2) giant larvae | 0.047 | |
cact | cactus | 0.046 | |
LanA | Laminin A | 0.045 | |
nej | nejire | 0.045 | |
cdi | center divider | 0.043 | |
Tl | Toll | 0.043 | |
CG13792 | CG13792 gene product from transcript CG13792-RA | 0.041 | |
Rac2 | CG8556 gene product from transcript CG8556-RA | 0.040 | |
hep | hemipterous | 0.039 | |
Rel | Relish | 0.035 | |
wun | wunen | 0.035 | |
Rab5 | Rab-protein 5 | 0.032 | |
htl | heartless | 0.032 | |
Cdc42 | CG12530 gene product from transcript CG12530-RA | 0.031 | |
RhoGAP100F | CG1976 gene product from transcript CG1976-RB | 0.031 | |
Stim | Stromal interaction molecule | 0.031 | |
Gpdh | Glycerol 3 phosphate dehydrogenase | 0.030 | |
Smox | Smad on X | 0.029 | |
Pvr | PDGF- and VEGF-receptor related | 0.029 | |
ash1 | absent, small, or homeotic discs 1 | 0.028 | |
daw | dawdle | 0.027 | |
Adar | Adenosine deaminase acting on RNA | 0.027 | |
CG2116 | CG2116 gene product from transcript CG2116-RA | 0.026 | |
Mkk4 | MAP kinase kinase 4 | 0.026 | |
kek5 | kekkon5 | 0.026 | |
Sdc | Syndecan | 0.025 | |
Wnk | CG7177 gene product from transcript CG7177-RA | 0.025 | |
Ras85D | Ras oncogene at 85D | 0.024 | |
Pak | PAK-kinase | 0.024 | |
LamC | Lamin C | 0.024 | |
iav | inactive | 0.023 | |
mew | multiple edematous wings | 0.023 | |
trbl | tribbles | 0.023 | |
Sir2 | CG5216 gene product from transcript CG5216-RA | 0.023 | |
ash2 | absent, small, or homeotic discs 2 | 0.022 | |
MAPk-Ak2 | MAP kinase activated protein-kinase-2 | 0.022 | |
Max | CG9648 gene product from transcript CG9648-RA | 0.022 | |
eIF-4B | Eukaryotic initiation factor 4B | 0.022 | |
Hcf | Host cell factor | 0.022 | |
fwd | four wheel drive | 0.021 | |
mbc | myoblast city | 0.021 | |
Fs | Follistatin | 0.021 | |
Pkn | Protein kinase related to protein kinase N | 0.019 | |
Gnf1 | Germ line transcription factor 1 | 0.019 | |
Gyc76C | Guanylyl cyclase at 76C | 0.019 | |
chico | CG5686 gene product from transcript CG5686-RB | 0.018 | |
ens | ensconsin | 0.018 | |
fkh | fork head | 0.018 | |
Med | Medea | 0.018 | |
Rac1 | CG2248 gene product from transcript CG2248-RA | 0.018 | |
tefu | telomere fusion | 0.018 | |
S6k | RPS6-p70-protein kinase | 0.018 | |
sax | saxophone | 0.017 | |
rok | Rho-kinase | 0.017 | |
pll | pelle | 0.017 | |
Poxn | Pox neuro | 0.017 | |
G-oalpha47A | G protein oalpha 47A | 0.017 | |
cwo | clockwork orange | 0.016 | |
MTF-1 | Metal response element-binding Transcription Factor-1 | 0.016 | |
ftz-f1 | ftz transcription factor 1 | 0.016 | |
par-1 | CG8201 gene product from transcript CG8201-RA | 0.016 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 1.000 | |
SMAD4 | SMAD family member 4 | 1.000 | |
SMAD2 | SMAD family member 2 | 1.000 | |
SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 1.000 | |
SMAD7 | SMAD family member 7 | 1.000 | |
FHL2 | four and a half LIM domains 2 | 1.000 | |
SMAD3 | SMAD family member 3 | 1.000 | |
FN1 | fibronectin 1 | 1.000 | |
SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.998 | |
JUN | jun proto-oncogene | 0.998 | |
TP53 | tumor protein p53 | 0.997 | |
FLNA | filamin A, alpha | 0.997 | |
SMAD1 | SMAD family member 1 | 0.996 | |
SKIL | SKI-like oncogene | 0.990 | |
FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.990 | |
SMAD5 | SMAD family member 5 | 0.984 | |
TGFB1 | transforming growth factor, beta 1 | 0.983 | |
ENG | endoglin | 0.978 | |
ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.969 | |
FYN | FYN oncogene related to SRC, FGR, YES | 0.963 | |
TGFBR1 | transforming growth factor, beta receptor 1 | 0.953 | |
EP300 | E1A binding protein p300 | 0.949 | |
CREBBP | CREB binding protein | 0.948 | |
HIPK2 | homeodomain interacting protein kinase 2 | 0.932 | |
COL1A1 | collagen, type I, alpha 1 | 0.928 | |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.900 | |
FBLN1 | fibulin 1 | 0.870 | |
PXN | paxillin | 0.862 | |
MYC | v-myc myelocytomatosis viral oncogene homolog (avian) | 0.858 | |
WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.851 | |
COL3A1 | collagen, type III, alpha 1 | 0.850 | |
ATF3 | activating transcription factor 3 | 0.850 | |
ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.834 | |
SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.826 | |
VCL | vinculin | 0.785 | |
PDIA3 | protein disulfide isomerase family A, member 3 | 0.781 | |
USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.759 | |
MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.754 | |
MAP2K4 | mitogen-activated protein kinase kinase 4 | 0.750 | |
JUNB | jun B proto-oncogene | 0.749 | |
SNX9 | sorting nexin 9 | 0.748 | |
TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.731 | |
COL6A1 | collagen, type VI, alpha 1 | 0.709 | |
CAV1 | caveolin 1, caveolae protein, 22kDa | 0.704 | |
ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.696 | |
BMP2 | bone morphogenetic protein 2 | 0.693 | |
ELN | elastin | 0.689 | |
COL1A2 | collagen, type I, alpha 2 | 0.684 | |
BCAR1 | breast cancer anti-estrogen resistance 1 | 0.666 | |
TRIM33 | tripartite motif containing 33 | 0.662 | |
DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.661 | |
SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.648 | |
HIPK3 | homeodomain interacting protein kinase 3 | 0.637 | |
RANBP9 | RAN binding protein 9 | 0.635 | |
COL5A1 | collagen, type V, alpha 1 | 0.631 | |
LCK | lymphocyte-specific protein tyrosine kinase | 0.616 | |
ATF2 | activating transcription factor 2 | 0.604 | |
PTK2 | PTK2 protein tyrosine kinase 2 | 0.593 | |
ITGAV | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 0.592 | |
ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.581 | |
SNX6 | sorting nexin 6 | 0.562 | |
SMN1 | survival of motor neuron 1, telomeric | 0.553 | |
MAGEF1 | melanoma antigen family F, 1 | 0.546 | |
MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.545 | |
RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.541 | |
MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.540 | |
TGFB3 | transforming growth factor, beta 3 | 0.537 | |
FLNB | filamin B, beta | 0.534 | |
PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | 0.531 | |
UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.519 | |
CTBP1 | C-terminal binding protein 1 | 0.512 | |
SNX33 | sorting nexin 33 | 0.511 | |
AR | androgen receptor | 0.505 | |
PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.503 | |
NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like | 0.500 | |
MAPK8 | mitogen-activated protein kinase 8 | 0.487 | |
TBX5 | T-box 5 | 0.486 | |
COL4A1 | collagen, type IV, alpha 1 | 0.476 | |
PLEC | plectin | 0.459 | |
VCAM1 | vascular cell adhesion molecule 1 | 0.445 | |
ESR1 | estrogen receptor 1 | 0.432 | |
PDCD6IP | programmed cell death 6 interacting protein | 0.430 | |
ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.427 | |
SYK | spleen tyrosine kinase | 0.421 | |
COL6A2 | collagen, type VI, alpha 2 | 0.416 | |
CXXC5 | CXXC finger protein 5 | 0.409 | |
SOCS3 | suppressor of cytokine signaling 3 | 0.402 | |
PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.386 | |
FHL3 | four and a half LIM domains 3 | 0.383 | |
LMNA | lamin A/C | 0.377 | |
FKBP1A | FK506 binding protein 1A, 12kDa | 0.373 | |
SIRT1 | sirtuin 1 | 0.361 | |
ABI2 | abl-interactor 2 | 0.357 | |
POU3F2 | POU class 3 homeobox 2 | 0.350 | |
TCF4 | transcription factor 4 | 0.341 | |
SNX1 | sorting nexin 1 | 0.334 | |
WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.331 | |
TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | 0.315 | |
ITGA6 | integrin, alpha 6 | 0.311 | |
PTEN | phosphatase and tensin homolog | 0.302 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Col1a1 | collagen, type I, alpha 1 | 0.781 | |
Serpinh1 | serine (or cysteine) peptidase inhibitor, clade H, member 1 | 0.568 | |
Atf3 | activating transcription factor 3 | 0.462 | |
Bgn | biglycan | 0.451 | |
Lox | lysyl oxidase | 0.429 | |
Col3a1 | collagen, type III, alpha 1 | 0.408 | |
Dusp1 | dual specificity phosphatase 1 | 0.385 | |
Smad7 | SMAD family member 7 | 0.362 | |
Egr1 | early growth response 1 | 0.259 | |
Btg2 | BTG family, member 2 | 0.233 | |
Col1a2 | collagen, type I, alpha 2 | 0.202 | |
Lamc1 | laminin, gamma 1 | 0.189 | |
Loxl1 | lysyl oxidase-like 1 | 0.178 | |
Klf4 | Kruppel-like factor 4 (gut) | 0.174 | |
Lum | lumican | 0.171 | |
Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.144 | |
Tgfbr2 | transforming growth factor, beta receptor II | 0.138 | |
Jak2 | Janus kinase 2 | 0.129 | |
Pmepa1 | prostate transmembrane protein, androgen induced 1 | 0.123 | |
Nr4a1 | nuclear receptor subfamily 4, group A, member 1 | 0.118 | |
Adam17 | ADAM metallopeptidase domain 17 | 0.115 | |
Arnt | aryl hydrocarbon receptor nuclear translocator | 0.110 | |
Col5a2 | collagen, type V, alpha 2 | 0.102 | |
Ppp1r15a | protein phosphatase 1, regulatory (inhibitor) subunit 15A | 0.098 | |
Icam1 | intercellular adhesion molecule 1 | 0.098 | |
Runx1 | runt-related transcription factor 1 | 0.096 | |
Met | met proto-oncogene | 0.090 | |
Jun | Jun oncogene | 0.088 | |
Cish | cytokine inducible SH2-containing protein | 0.082 | |
Fos | FBJ osteosarcoma oncogene | 0.081 | |
Ier2 | immediate early response 2 | 0.081 | |
Stat6 | signal transducer and activator of transcription 6 | 0.080 | |
Slco2a1 | solute carrier organic anion transporter family, member 2a1 | 0.079 | |
Cpsf2 | cleavage and polyadenylation specific factor 2 | 0.076 | |
Eln | elastin | 0.074 | |
Rara | retinoic acid receptor, alpha | 0.073 | |
Junb | jun B proto-oncogene | 0.069 | |
Acta2 | smooth muscle alpha-actin | 0.069 | |
Pecam1 | platelet/endothelial cell adhesion molecule 1 | 0.066 | |
Gja4 | gap junction protein, alpha 4 | 0.060 | |
Psen1 | presenilin 1 | 0.056 | |
Aebp1 | AE binding protein 1 | 0.054 | |
Ntn1 | netrin 1 | 0.050 | |
Elk3 | ELK3, ETS-domain protein | 0.048 | |
Tgfb1 | transforming growth factor, beta 1 | 0.047 | |
Postn | periostin, osteoblast specific factor | 0.047 | |
Cyr61 | cysteine-rich, angiogenic inducer, 61 | 0.047 | |
Col6a2 | collagen, type VI, alpha 2 | 0.044 | |
Smad1 | SMAD family member 1 | 0.044 | |
Agtr1a | angiotensin II receptor, type 1a | 0.043 | |
Ggt5 | gamma-glutamyltransferase 5 | 0.043 | |
Ncan | neurocan | 0.042 | |
Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.042 | |
S1pr2 | sphingosine-1-phosphate receptor 2 | 0.040 | |
Tgfbr1 | transforming growth factor, beta receptor 1 | 0.040 | |
Mfap5 | microfibrillar associated protein 5 | 0.038 | |
Klf6 | Kruppel-like factor 6 | 0.037 | |
Emp1 | epithelial membrane protein 1 | 0.036 | |
Col12a1 | collagen, type XII, alpha 1 | 0.036 | |
Jak1 | Janus kinase 1 | 0.035 | |
Fgd4 | FYVE, RhoGEF and PH domain containing 4 | 0.035 | |
Socs2 | suppressor of cytokine signaling 2 | 0.035 | |
Myh9 | myosin, heavy chain 9, non-muscle | 0.035 | |
Dcn | decorin | 0.035 | |
Tgfb3 | transforming growth factor, beta 3 | 0.034 | |
Ecm1 | extracellular matrix protein 1 | 0.033 | |
Usf2 | upstream transcription factor 2, c-fos interacting | 0.032 | |
Cdh5 | cadherin 5 | 0.031 | |
Sh2b1 | SH2B adaptor protein 1 | 0.031 | |
Ctsk | cathepsin K | 0.031 | |
Nln | neurolysin (metallopeptidase M3 family) | 0.030 | |
Nr4a3 | nuclear receptor subfamily 4, group A, member 3 | 0.030 | |
Igf2r | insulin-like growth factor 2 receptor | 0.030 | |
Zfp36 | zinc finger protein 36 | 0.029 | |
Casp3 | caspase 3 | 0.029 | |
Bcar1 | breast cancer anti-estrogen resistance 1 | 0.028 | |
Mark2 | MAP/microtubule affinity-regulating kinase 2 | 0.028 | |
Col4a1 | collagen, type IV, alpha 1 | 0.028 | |
Smad3 | SMAD family member 3 | 0.027 | |
Rgs19 | regulator of G-protein signaling 19 | 0.027 | |
Plaur | plasminogen activator, urokinase receptor | 0.027 | |
Map3k7ip2 | mitogen-activated protein kinase kinase kinase 7 interacting protein 2 | 0.026 | |
Raf1 | v-raf-leukemia viral oncogene 1 | 0.026 | |
Nck1 | NCK adaptor protein 1 | 0.024 | |
Ucp2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.024 | |
Fam38a | family with sequence similarity 38, member A | 0.024 | |
Gsk3b | glycogen synthase kinase 3 beta | 0.024 | |
Hspa13 | heat shock protein 13 | 0.023 | |
Egr2 | early growth response 2 | 0.023 | |
Hspa1a | heat shock 70kD protein 1A | 0.023 | |
Coq10b | coenzyme Q10 homolog B (S. cerevisiae) | 0.023 | |
Casp7 | caspase 7 | 0.022 | |
Sox17 | SRY (sex determining region Y)-box 17 | 0.022 | |
Mdm2 | Mdm2 p53 binding protein homolog (mouse) | 0.022 | |
Trim47 | tripartite motif-containing 47 | 0.022 | |
Pdia4 | protein disulfide isomerase family A, member 4 | 0.022 | |
Cast | calpastatin | 0.022 | |
Itgb1 | integrin, beta 1 | 0.022 | |
Mafb | v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) | 0.022 | |
Il1rap | interleukin 1 receptor accessory protein | 0.022 |