The network for 'lymphocyte apoptotic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

lymphocyte apoptotic process

Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.

Mus musculus
Name Description Probability Func Analog Organism
Igh immunoglobulin heavy chain complex 0.991
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.989
Pten phosphatase and tensin homolog 0.989
Trp53 transformation related protein 53 0.986
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.961
Hif1a hypoxia inducible factor 1, alpha subunit 0.936
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.868
Fas Fas (TNF receptor superfamily member 6) 0.852
Cd19 CD19 antigen 0.851
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.756
Bcl2 B-cell leukemia/lymphoma 2 0.753
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.752
Cd40 CD40 antigen 0.739
Lyz2 lysozyme 2 0.649
Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.601
Bax BCL2-associated X protein 0.562
Lepr leptin receptor 0.556
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.550
Traf2 TNF receptor-associated factor 2 0.548
Csf1 colony stimulating factor 1 (macrophage) 0.547
Myd88 myeloid differentiation primary response gene 88 0.517
Ctnnb1 catenin (cadherin associated protein), beta 1 0.517
Kit kit oncogene 0.515
Il1r1 interleukin 1 receptor, type I 0.498
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.473
Pax3 paired box gene 3 0.469
Traf6 TNF receptor-associated factor 6 0.466
Tnf tumor necrosis factor 0.463
Tlr4 toll-like receptor 4 0.457
Trp73 transformation related protein 73 0.436
Fgfr2 fibroblast growth factor receptor 2 0.420
Egfr epidermal growth factor receptor 0.386
Cd44 CD44 antigen 0.375
Insr insulin receptor 0.361
Fgf10 fibroblast growth factor 10 0.335
Rara retinoic acid receptor, alpha 0.332
Socs1 suppressor of cytokine signaling 1 0.330
Il10 interleukin 10 0.306
Pnp2 purine-nucleoside phosphorylase 2 0.295
Casp8 caspase 8 0.292
Gdnf glial cell line derived neurotrophic factor 0.291
Pax2 paired box gene 2 0.290
Wnt6 wingless-related MMTV integration site 6 0.290
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.281
Rxra retinoid X receptor alpha 0.281
Dffb DNA fragmentation factor, beta subunit 0.280
Wnt3a wingless-related MMTV integration site 3A 0.277
Adam12 a disintegrin and metallopeptidase domain 12 (meltrin alpha) 0.273
Foxn1 forkhead box N1 0.267
Lck lymphocyte protein tyrosine kinase 0.266
Lat linker for activation of T cells 0.260
Wnt4 wingless-related MMTV integration site 4 0.258
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.257
Ptgs2 prostaglandin-endoperoxide synthase 2 0.252
Gli3 GLI-Kruppel family member GLI3 0.250
Spib Spi-B transcription factor (Spi-1/PU.1 related) 0.237
Rarg retinoic acid receptor, gamma 0.235
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.222
Bmp4 bone morphogenetic protein 4 0.218
Adam17 a disintegrin and metallopeptidase domain 17 0.216
Plcg2 phospholipase C, gamma 2 0.212
Icos inducible T-cell co-stimulator 0.210
Nos3 nitric oxide synthase 3, endothelial cell 0.209
Dok1 docking protein 1 0.200
Grb2 growth factor receptor bound protein 2 0.197
Ptch2 patched homolog 2 0.190
Stat3 signal transducer and activator of transcription 3 0.189
Apoe apolipoprotein E 0.186
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.183
Foxf1a forkhead box F1a 0.182
Meox2 mesenchyme homeobox 2 0.181
Lhx1 LIM homeobox protein 1 0.178
Tnfrsf13c tumor necrosis factor receptor superfamily, member 13c 0.178
Wt1 Wilms tumor 1 homolog 0.176
Cd5 CD5 antigen 0.172
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.165
Adam19 a disintegrin and metallopeptidase domain 19 (meltrin beta) 0.163
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.159
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.155
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.152
Anxa4 annexin A4 0.151
Pax8 paired box gene 8 0.148
Bcl6 B-cell leukemia/lymphoma 6 0.146
Efs embryonal Fyn-associated substrate 0.142
Socs3 suppressor of cytokine signaling 3 0.142
Ctsw cathepsin W 0.138
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 0.138
Pou3f2 POU domain, class 3, transcription factor 2 0.137
Icam1 intercellular adhesion molecule 1 0.135
Bcl2l1 BCL2-like 1 0.134
Irf4 interferon regulatory factor 4 0.131
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.130
Plaur plasminogen activator, urokinase receptor 0.129
Il2rb interleukin 2 receptor, beta chain 0.128
Ret ret proto-oncogene 0.126
Fgfr1 fibroblast growth factor receptor 1 0.123
Sh2d2a SH2 domain protein 2A 0.120
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.119
Egln1 EGL nine homolog 1 (C. elegans) 0.119
Wnt7b wingless-related MMTV integration site 7B 0.118
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.000
TRAF1 TNF receptor-associated factor 1 0.995
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.992
BCL2 B-cell CLL/lymphoma 2 0.986
CFLAR CASP8 and FADD-like apoptosis regulator 0.984
BAX BCL2-associated X protein 0.935
BCL2L1 BCL2-like 1 0.926
FAS Fas (TNF receptor superfamily, member 6) 0.925
FADD Fas (TNFRSF6)-associated via death domain 0.917
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.916
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.906
BIRC3 baculoviral IAP repeat containing 3 0.854
BID BH3 interacting domain death agonist 0.839
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.823
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) 0.801
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.766
CCR5 chemokine (C-C motif) receptor 5 0.742
CD2 CD2 molecule 0.685
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 0.665
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.646
TRAF2 TNF receptor-associated factor 2 0.598
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.546
IL10RA interleukin 10 receptor, alpha 0.523
CCL4 chemokine (C-C motif) ligand 4 0.468
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 0.466
BMPR1A bone morphogenetic protein receptor, type IA 0.450
FASLG Fas ligand (TNF superfamily, member 6) 0.437
CCR7 chemokine (C-C motif) receptor 7 0.415
INSR insulin receptor 0.408
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.390
LCK lymphocyte-specific protein tyrosine kinase 0.337
TP53 tumor protein p53 0.335
LTA lymphotoxin alpha (TNF superfamily, member 1) 0.333
TRADD TNFRSF1A-associated via death domain 0.251
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) 0.224
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.198
BAD BCL2-associated agonist of cell death 0.196
FYN FYN oncogene related to SRC, FGR, YES 0.191
NOXA1 NADPH oxidase activator 1 0.190
IL22RA1 interleukin 22 receptor, alpha 1 0.181
TRAF3 TNF receptor-associated factor 3 0.177
SQSTM1 sequestosome 1 0.175
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 0.170
S100A6 S100 calcium binding protein A6 0.167
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.167
CCL5 chemokine (C-C motif) ligand 5 0.158
CXCR4 chemokine (C-X-C motif) receptor 4 0.156
CCL13 chemokine (C-C motif) ligand 13 0.150
TGIF1 TGFB-induced factor homeobox 1 0.139
CARD11 caspase recruitment domain family, member 11 0.126
BAK1 BCL2-antagonist/killer 1 0.124
RIPK2 receptor-interacting serine-threonine kinase 2 0.123
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.117
CDC37 cell division cycle 37 homolog (S. cerevisiae) 0.113
MSN moesin 0.108
CXCL9 chemokine (C-X-C motif) ligand 9 0.104
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.102
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.091
CCL8 chemokine (C-C motif) ligand 8 0.090
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.088
S100A4 S100 calcium binding protein A4 0.087
IL2RB interleukin 2 receptor, beta 0.085
CD28 CD28 molecule 0.082
TNF tumor necrosis factor 0.081
CD80 CD80 molecule 0.080
CD3G CD3g molecule, gamma (CD3-TCR complex) 0.078
VIM vimentin 0.072
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.072
BIRC2 baculoviral IAP repeat containing 2 0.070
PARD6A par-6 partitioning defective 6 homolog alpha (C. elegans) 0.068
IL2RG interleukin 2 receptor, gamma 0.067
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.066
IL32 interleukin 32 0.066
INCENP inner centromere protein antigens 135/155kDa 0.066
CD40 CD40 molecule, TNF receptor superfamily member 5 0.065
PXMP2 peroxisomal membrane protein 2, 22kDa 0.064
IL10 interleukin 10 0.062
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.062
CD48 CD48 molecule 0.059
PRKCZ protein kinase C, zeta 0.058
PDPK1 3-phosphoinositide dependent protein kinase-1 0.057
PTPRC protein tyrosine phosphatase, receptor type, C 0.055
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.055
IL2RA interleukin 2 receptor, alpha 0.054
TP53BP2 tumor protein p53 binding protein, 2 0.054
IL22RA2 interleukin 22 receptor, alpha 2 0.052
SOCS3 suppressor of cytokine signaling 3 0.051
CD5 CD5 molecule 0.050
ANXA2 annexin A2 0.049
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.049
IFNG interferon, gamma 0.049
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.048
GRB10 growth factor receptor-bound protein 10 0.047
SH2D1A SH2 domain containing 1A 0.046
IDE insulin-degrading enzyme 0.044
C9orf89 chromosome 9 open reading frame 89 0.044
PARD6G par-6 partitioning defective 6 homolog gamma (C. elegans) 0.043
APAF1 apoptotic peptidase activating factor 1 0.043
CAV1 caveolin 1, caveolae protein, 22kDa 0.043
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.043
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism