IMP
Process View
The network for 'regulation of mast cell activation involved in immune response' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
regulation of mast cell activation involved in immune response
Any process that modulates the frequency, rate, or extent of mast cell activation as part of an immune response.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Inpp5d | inositol polyphosphate-5-phosphatase D | 0.996 | |
| Cd247 | CD247 antigen | 0.995 | |
| Grb2 | growth factor receptor bound protein 2 | 0.993 | |
| Csf2rb2 | colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) | 0.983 | |
| Ikzf1 | IKAROS family zinc finger 1 | 0.965 | |
| Csf2rb | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.959 | |
| Mefv | Mediterranean fever | 0.946 | |
| Fcer1g | Fc receptor, IgE, high affinity I, gamma polypeptide | 0.913 | |
| Ptprc | protein tyrosine phosphatase, receptor type, C | 0.885 | |
| Lat | linker for activation of T cells | 0.839 | |
| Tyrobp | TYRO protein tyrosine kinase binding protein | 0.820 | |
| Tcra | T-cell receptor alpha chain | 0.807 | |
| Dok1 | docking protein 1 | 0.771 | |
| Il4 | interleukin 4 | 0.770 | |
| Ptk2 | PTK2 protein tyrosine kinase 2 | 0.760 | |
| Hcst | hematopoietic cell signal transducer | 0.737 | |
| Cd22 | CD22 antigen | 0.697 | |
| Il2 | interleukin 2 | 0.685 | |
| AF251705 | cDNA sequence AF251705 | 0.617 | |
| Csf1r | colony stimulating factor 1 receptor | 0.580 | |
| Shc1 | src homology 2 domain-containing transforming protein C1 | 0.526 | |
| Cbl | Casitas B-lineage lymphoma | 0.521 | |
| Dok3 | docking protein 3 | 0.386 | |
| Dok2 | docking protein 2 | 0.360 | |
| Pik3r1 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 0.355 | |
| Cd4 | CD4 antigen | 0.332 | |
| Il2rb | interleukin 2 receptor, beta chain | 0.301 | |
| Cd40 | CD40 antigen | 0.294 | |
| Ccr6 | chemokine (C-C motif) receptor 6 | 0.267 | |
| Lgr4 | leucine-rich repeat-containing G protein-coupled receptor 4 | 0.264 | |
| Hck | hemopoietic cell kinase | 0.251 | |
| Il2rg | interleukin 2 receptor, gamma chain | 0.226 | |
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.210 | |
| Cd180 | CD180 antigen | 0.186 | |
| Met | met proto-oncogene | 0.172 | |
| Mb | myoglobin | 0.167 | |
| Snai1 | snail homolog 1 (Drosophila) | 0.154 | |
| Cd79a | CD79A antigen (immunoglobulin-associated alpha) | 0.143 | |
| Msr1 | macrophage scavenger receptor 1 | 0.140 | |
| Grap2 | GRB2-related adaptor protein 2 | 0.134 | |
| Nfam1 | Nfat activating molecule with ITAM motif 1 | 0.126 | |
| C5ar1 | complement component 5a receptor 1 | 0.113 | |
| Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.106 | |
| Spib | Spi-B transcription factor (Spi-1/PU.1 related) | 0.105 | |
| Il4ra | interleukin 4 receptor, alpha | 0.102 | |
| Stat6 | signal transducer and activator of transcription 6 | 0.101 | |
| Trpv1 | transient receptor potential cation channel, subfamily V, member 1 | 0.099 | |
| Tbxas1 | thromboxane A synthase 1, platelet | 0.092 | |
| S1pr4 | sphingosine-1-phosphate receptor 4 | 0.089 | |
| Cd68 | CD68 antigen | 0.086 | |
| Il13 | interleukin 13 | 0.084 | |
| Hlx | H2.0-like homeobox | 0.082 | |
| BC013712 | cDNA sequence BC013712 | 0.078 | |
| Slc11a1 | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 | 0.074 | |
| Prkce | protein kinase C, epsilon | 0.073 | |
| Csf3r | colony stimulating factor 3 receptor (granulocyte) | 0.072 | |
| Ifng | interferon gamma | 0.071 | |
| Il10ra | interleukin 10 receptor, alpha | 0.071 | |
| Plcg1 | phospholipase C, gamma 1 | 0.071 | |
| H2-DMb2 | histocompatibility 2, class II, locus Mb2 | 0.071 | |
| Cmklr1 | chemokine-like receptor 1 | 0.070 | |
| Lyn | Yamaguchi sarcoma viral (v-yes-1) oncogene homolog | 0.066 | |
| Jak2 | Janus kinase 2 | 0.066 | |
| Cd300a | CD300A antigen | 0.065 | |
| Fcgr3 | Fc receptor, IgG, low affinity III | 0.063 | |
| Cd6 | CD6 antigen | 0.060 | |
| Irf5 | interferon regulatory factor 5 | 0.059 | |
| Gpr35 | G protein-coupled receptor 35 | 0.058 | |
| Lyl1 | lymphoblastomic leukemia 1 | 0.056 | |
| Was | Wiskott-Aldrich syndrome homolog (human) | 0.056 | |
| Pou2f2 | POU domain, class 2, transcription factor 2 | 0.056 | |
| Lcn4 | lipocalin 4 | 0.054 | |
| Ptgir | prostaglandin I receptor (IP) | 0.053 | |
| Fes | feline sarcoma oncogene | 0.053 | |
| Batf3 | basic leucine zipper transcription factor, ATF-like 3 | 0.052 | |
| Cr2 | complement receptor 2 | 0.052 | |
| Hcls1 | hematopoietic cell specific Lyn substrate 1 | 0.049 | |
| Zap70 | zeta-chain (TCR) associated protein kinase | 0.049 | |
| Emr1 | EGF-like module containing, mucin-like, hormone receptor-like sequence 1 | 0.048 | |
| 4632428N05Rik | RIKEN cDNA 4632428N05 gene | 0.048 | |
| Blk | B lymphoid kinase | 0.048 | |
| Clec4n | C-type lectin domain family 4, member n | 0.047 | |
| Cxcr3 | chemokine (C-X-C motif) receptor 3 | 0.047 | |
| Plekho2 | pleckstrin homology domain containing, family O member 2 | 0.046 | |
| Itgb3 | integrin beta 3 | 0.045 | |
| Galnt6 | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 | 0.044 | |
| Trem3 | triggering receptor expressed on myeloid cells 3 | 0.044 | |
| Fyn | Fyn proto-oncogene | 0.044 | |
| Plcg2 | phospholipase C, gamma 2 | 0.043 | |
| Pik3cd | phosphatidylinositol 3-kinase catalytic delta polypeptide | 0.043 | |
| Pik3cg | phosphoinositide-3-kinase, catalytic, gamma polypeptide | 0.043 | |
| Cxcr5 | chemokine (C-X-C motif) receptor 5 | 0.041 | |
| Sfpi1 | SFFV proviral integration 1 | 0.040 | |
| Ager | advanced glycosylation end product-specific receptor | 0.040 | |
| Tcirg1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 | 0.039 | |
| Hrh1 | histamine receptor H1 | 0.038 | |
| Rac2 | RAS-related C3 botulinum substrate 2 | 0.038 | |
| P2rx7 | purinergic receptor P2X, ligand-gated ion channel, 7 | 0.037 | |
| Blnk | B-cell linker | 0.036 | |
| Fgr | Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog | 0.036 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| LCK | lymphocyte-specific protein tyrosine kinase | 0.942 | |
| SYK | spleen tyrosine kinase | 0.813 | |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.574 | |
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.499 | |
| BLNK | B-cell linker | 0.456 | |
| WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.385 | |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | 0.317 | |
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.263 | |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.253 | |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.232 | |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.200 | |
| FGR | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.154 | |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.148 | |
| TFF1 | trefoil factor 1 | 0.146 | |
| IL4R | interleukin 4 receptor | 0.138 | |
| ZNF746 | zinc finger protein 746 | 0.125 | |
| C19orf50 | chromosome 19 open reading frame 50 | 0.106 | |
| IL4 | interleukin 4 | 0.084 | |
| CRH | corticotropin releasing hormone | 0.064 | |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | 0.062 | |
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.062 | |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | 0.058 | |
| BAI1 | brain-specific angiogenesis inhibitor 1 | 0.053 | |
| CARD11 | caspase recruitment domain family, member 11 | 0.048 | |
| VAV1 | vav 1 guanine nucleotide exchange factor | 0.045 | |
| BTK | Bruton agammaglobulinemia tyrosine kinase | 0.044 | |
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.033 | |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.033 | |
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 | 0.032 | |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 0.031 | |
| LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.028 | |
| HCK | hemopoietic cell kinase | 0.028 | |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.027 | |
| ERBB4 | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 0.024 | |
| IL2RG | interleukin 2 receptor, gamma | 0.024 | |
| GRB2 | growth factor receptor-bound protein 2 | 0.023 | |
| SLA | Src-like-adaptor | 0.019 | |
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | 0.019 | |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 | 0.019 | |
| IFT20 | intraflagellar transport 20 homolog (Chlamydomonas) | 0.019 | |
| PARK2 | parkinson protein 2, E3 ubiquitin protein ligase (parkin) | 0.018 | |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 | 0.017 | |
| HK3 | hexokinase 3 (white cell) | 0.016 | |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.016 | |
| GRAP2 | GRB2-related adaptor protein 2 | 0.015 | |
| DUSP23 | dual specificity phosphatase 23 | 0.015 | |
| GAB1 | GRB2-associated binding protein 1 | 0.014 | |
| CSF3R | colony stimulating factor 3 receptor (granulocyte) | 0.014 | |
| SASH3 | SAM and SH3 domain containing 3 | 0.013 | |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | 0.013 | |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 | 0.013 | |
| NSF | N-ethylmaleimide-sensitive factor | 0.013 | |
| KRT81 | keratin 81 | 0.013 | |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | 0.013 | |
| DOK3 | docking protein 3 | 0.013 | |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) | 0.012 | |
| PIM1 | pim-1 oncogene | 0.012 | |
| EPHA8 | EPH receptor A8 | 0.012 | |
| HDC | histidine decarboxylase | 0.012 | |
| PECAM1 | platelet/endothelial cell adhesion molecule | 0.012 | |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 0.012 | |
| ZC3HC1 | zinc finger, C3HC-type containing 1 | 0.012 | |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 | 0.012 | |
| SIRPB1 | signal-regulatory protein beta 1 | 0.012 | |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 0.012 | |
| BCL10 | B-cell CLL/lymphoma 10 | 0.011 | |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) | 0.011 | |
| GAS7 | growth arrest-specific 7 | 0.011 | |
| FNBP1 | formin binding protein 1 | 0.011 | |
| HPGDS | hematopoietic prostaglandin D synthase | 0.011 | |
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.011 | |
| PHAX | phosphorylated adaptor for RNA export | 0.011 | |
| ILK | integrin-linked kinase | 0.011 | |
| SNX33 | sorting nexin 33 | 0.011 | |
| CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.010 | |
| PLCG1 | phospholipase C, gamma 1 | 0.010 | |
| PRKCB | protein kinase C, beta | 0.010 | |
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) | 0.010 | |
| TYROBP | TYRO protein tyrosine kinase binding protein | 0.010 | |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 0.010 | |
| PACSIN1 | protein kinase C and casein kinase substrate in neurons 1 | 0.010 |
Loading network...
Rattus norvegicus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Hck | hemopoietic cell kinase | 0.045 | |
| Folr2 | folate receptor 2 (fetal) | 0.039 | |
| Tgfbr2 | transforming growth factor, beta receptor II | 0.031 | |
| Cybb | cytochrome b-245, beta polypeptide | 0.025 | |
| Arl11 | ADP-ribosylation factor-like 11 | 0.024 | |
| Ptprc | protein tyrosine phosphatase, receptor type, C | 0.021 | |
| Galr2 | galanin receptor 2 | 0.018 | |
| Cfp | complement factor properdin | 0.017 | |
| C5ar1 | complement component 5a receptor 1 | 0.016 | |
| RGD1310262 | hypothetical LOC304650 | 0.015 | |
| Inpp5d | inositol polyphosphate-5-phosphatase D | 0.015 | |
| Mpeg1 | macrophage expressed 1 | 0.014 | |
| Tgfbr3 | transforming growth factor, beta receptor III | 0.014 | |
| Tnfrsf8 | tumor necrosis factor receptor superfamily, member 8 | 0.012 | |
| Itpr2 | inositol 1,4,5-triphosphate receptor, type 2 | 0.012 | |
| Hand1 | heart and neural crest derivatives expressed 1 | 0.012 | |
| Lyn | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.012 | |
| Oprm1 | opioid receptor, mu 1 | 0.012 | |
| Tbxas1 | thromboxane A synthase 1, platelet | 0.012 | |
| Srxn1 | sulfiredoxin 1 homolog (S. cerevisiae) | 0.012 | |
| Ptpn18 | protein tyrosine phosphatase, non-receptor type 18 | 0.011 | |
| Cd38 | CD38 molecule | 0.011 | |
| RGD1559588 | similar to cell surface receptor FDFACT | 0.011 | |
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.011 | |
| Bdkrb2 | bradykinin receptor B2 | 0.011 | |
| Ptger2 | prostaglandin E receptor 2 (subtype EP2) | 0.011 | |
| Ptafr | platelet-activating factor receptor | 0.011 | |
| Ccr5 | chemokine (C-C motif) receptor 5 | 0.010 | |
| Slc9a1 | solute carrier family 9 (sodium/hydrogen exchanger), member 1 | 0.010 | |
| St8sia4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 | 0.010 | |
| Igsf7 | immunoglobulin superfamily, member 7 | 0.010 |