Process View
The network for 'erbb signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptor tyrosine kinases on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.988 | |
Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.959 | |
Grb2 | growth factor receptor bound protein 2 | 0.950 | |
Inpp5d | inositol polyphosphate-5-phosphatase D | 0.887 | |
Lepr | leptin receptor | 0.879 | |
App | amyloid beta (A4) precursor protein | 0.728 | |
Erbb3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.679 | |
Egfr | epidermal growth factor receptor | 0.642 | |
Fgfr2 | fibroblast growth factor receptor 2 | 0.633 | |
Nf1 | neurofibromatosis 1 | 0.579 | |
Shc1 | src homology 2 domain-containing transforming protein C1 | 0.573 | |
Prnp | prion protein | 0.511 | |
Grin1 | glutamate receptor, ionotropic, NMDA1 (zeta 1) | 0.490 | |
Ret | ret proto-oncogene | 0.471 | |
Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.468 | |
Notch1 | Notch gene homolog 1 (Drosophila) | 0.453 | |
Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.444 | |
Psen1 | presenilin 1 | 0.421 | |
Cbl | Casitas B-lineage lymphoma | 0.402 | |
Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.326 | |
Mapk8ip1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.314 | |
Pten | phosphatase and tensin homolog | 0.301 | |
Dab1 | disabled homolog 1 (Drosophila) | 0.294 | |
Stat3 | signal transducer and activator of transcription 3 | 0.281 | |
Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.268 | |
Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.255 | |
Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.250 | |
Ptk2 | PTK2 protein tyrosine kinase 2 | 0.240 | |
Bdnf | brain derived neurotrophic factor | 0.237 | |
Vav2 | vav 2 oncogene | 0.224 | |
Blnk | B-cell linker | 0.220 | |
Pik3r1 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 0.214 | |
Eda | ectodysplasin-A | 0.210 | |
Src | Rous sarcoma oncogene | 0.197 | |
Nrg1 | neuregulin 1 | 0.192 | |
Jak2 | Janus kinase 2 | 0.187 | |
Btk | Bruton agammaglobulinemia tyrosine kinase | 0.182 | |
Ntf3 | neurotrophin 3 | 0.165 | |
Pax6 | paired box gene 6 | 0.163 | |
Vav1 | vav 1 oncogene | 0.161 | |
Notch2 | Notch gene homolog 2 (Drosophila) | 0.159 | |
Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.149 | |
Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.149 | |
Crk | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.140 | |
Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.140 | |
Pik3ca | phosphatidylinositol 3-kinase, catalytic, alpha polypeptide | 0.140 | |
Dlg4 | discs, large homolog 4 (Drosophila) | 0.135 | |
Tgfbr1 | transforming growth factor, beta receptor I | 0.134 | |
Usp8 | ubiquitin specific peptidase 8 | 0.132 | |
Il6st | interleukin 6 signal transducer | 0.128 | |
Was | Wiskott-Aldrich syndrome homolog (human) | 0.116 | |
Vegfa | vascular endothelial growth factor A | 0.116 | |
Trp53 | transformation related protein 53 | 0.115 | |
Abl1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.113 | |
Crkl | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.110 | |
Phox2b | paired-like homeobox 2b | 0.108 | |
Pstpip1 | proline-serine-threonine phosphatase-interacting protein 1 | 0.108 | |
Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.105 | |
Plcg1 | phospholipase C, gamma 1 | 0.104 | |
Phox2a | paired-like homeobox 2a | 0.101 | |
Cd79a | CD79A antigen (immunoglobulin-associated alpha) | 0.092 | |
Dlg1 | discs, large homolog 1 (Drosophila) | 0.088 | |
Pdgfb | platelet derived growth factor, B polypeptide | 0.087 | |
Prkcb | protein kinase C, beta | 0.087 | |
Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.086 | |
Rac1 | RAS-related C3 botulinum substrate 1 | 0.086 | |
Arid1a | AT rich interactive domain 1A (SWI-like) | 0.085 | |
Tbx3 | T-box 3 | 0.085 | |
Rassf5 | Ras association (RalGDS/AF-6) domain family member 5 | 0.085 | |
Sox10 | SRY-box containing gene 10 | 0.084 | |
Gab2 | growth factor receptor bound protein 2-associated protein 2 | 0.084 | |
Npc1 | Niemann Pick type C1 | 0.083 | |
Cask | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.083 | |
Dok1 | docking protein 1 | 0.078 | |
Rbpj | recombination signal binding protein for immunoglobulin kappa J region | 0.078 | |
Erbb2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.076 | |
Tgfbr2 | transforming growth factor, beta receptor II | 0.076 | |
L1cam | L1 cell adhesion molecule | 0.075 | |
Fgfr3 | fibroblast growth factor receptor 3 | 0.075 | |
Nos3 | nitric oxide synthase 3, endothelial cell | 0.075 | |
Gfra1 | glial cell line derived neurotrophic factor family receptor alpha 1 | 0.074 | |
Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.073 | |
Lyn | Yamaguchi sarcoma viral (v-yes-1) oncogene homolog | 0.071 | |
Dll4 | delta-like 4 (Drosophila) | 0.070 | |
Alx3 | aristaless-like homeobox 3 | 0.070 | |
Atf2 | activating transcription factor 2 | 0.069 | |
Psap | prosaposin | 0.068 | |
Hras1 | Harvey rat sarcoma virus oncogene 1 | 0.067 | |
Smarcc1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.067 | |
Gab1 | growth factor receptor bound protein 2-associated protein 1 | 0.066 | |
Prkce | protein kinase C, epsilon | 0.066 | |
Crebbp | CREB binding protein | 0.059 | |
Sp1 | trans-acting transcription factor 1 | 0.059 | |
Itga3 | integrin alpha 3 | 0.059 | |
Met | met proto-oncogene | 0.057 | |
Vav3 | vav 3 oncogene | 0.057 | |
Efnb2 | ephrin B2 | 0.057 | |
Hhex | hematopoietically expressed homeobox | 0.057 | |
Sos1 | son of sevenless homolog 1 (Drosophila) | 0.056 | |
Cd22 | CD22 antigen | 0.056 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
let-60 | Protein LET-60 | 0.628 | |
eps-8 | Protein EPS-8 | 0.188 | |
mek-2 | Protein MEK-2 | 0.168 | |
ajm-1 | Protein AJM-1 | 0.109 | |
akt-1 | Protein AKT-1 | 0.074 | |
egl-15 | Protein EGL-15 | 0.069 | |
egl-30 | Protein EGL-30 | 0.065 | |
rbr-2 | Protein RBR-2 | 0.055 | |
vab-1 | Protein VAB-1 | 0.055 | |
egl-27 | Protein EGL-27 | 0.045 | |
C11E4.6 | Protein C11E4.6 | 0.044 | |
egl-8 | Protein EGL-8 | 0.036 | |
lst-1 | Protein LST-1 | 0.031 | |
pept-3 | Protein PEPT-3 | 0.030 | |
R03H10.2 | Protein R03H10.2 | 0.024 | |
inx-1 | Protein INX-1 | 0.024 | |
M02B1.3 | Protein M02B1.3 | 0.023 | |
egl-26 | Protein EGL-26 | 0.022 | |
alg-1 | Protein ALG-1 | 0.021 | |
emo-1 | Protein EMO-1 | 0.021 | |
gpb-1 | Protein GPB-1 | 0.020 | |
sem-5 | Protein SEM-5 | 0.020 | |
cmd-1 | Protein CMD-1 | 0.020 | |
CELE_H28G03.1 | Protein H28G03.1 | 0.020 | |
pqe-1 | Protein PQE-1 | 0.020 | |
mca-2 | Protein MCA-2 | 0.020 | |
daf-11 | Protein DAF-11 | 0.019 | |
csnk-1 | Protein CSNK-1 | 0.018 | |
mig-6 | Protein MIG-6 | 0.018 | |
ina-1 | Protein INA-1 | 0.018 | |
lag-1 | Protein LAG-1 | 0.018 | |
clr-1 | Protein CLR-1 | 0.018 | |
vab-3 | Protein VAB-3 | 0.017 | |
ykt-6 | Protein YKT-6 | 0.017 | |
emb-5 | Protein EMB-5 | 0.017 | |
sel-8 | Protein SEL-8 | 0.015 | |
fln-2 | Protein FLN-2 | 0.015 | |
sma-1 | Protein SMA-1 | 0.015 | |
miz-1 | Protein MIZ-1 | 0.015 | |
egl-13 | Protein EGL-13 | 0.014 | |
CELE_C10C6.6 | Protein C10C6.6 | 0.014 | |
CELE_F52E1.9 | Protein F52E1.9 | 0.014 | |
clc-3 | Protein CLC-3 | 0.014 | |
soc-2 | Protein SOC-2 | 0.013 | |
unc-115 | Protein UNC-115 | 0.013 | |
bar-1 | Protein BAR-1 | 0.013 | |
wwp-1 | Protein WWP-1 | 0.013 | |
plc-1 | Protein PLC-1 | 0.013 | |
ZK512.4 | Protein ZK512.4 | 0.013 | |
ZK1127.6 | Protein ZK1127.6 | 0.012 | |
dmd-7 | Protein DMD-7 | 0.012 | |
vab-10 | Protein VAB-10 | 0.012 | |
egl-38 | Protein EGL-38 | 0.012 | |
K06A9.1 | Protein K06A9.1 | 0.012 | |
mpk-1 | Protein MPK-1 | 0.012 | |
vav-1 | Protein VAV-1 | 0.012 | |
lin-2 | Protein LIN-2 | 0.012 | |
dpy-23 | Protein DPY-23 | 0.012 | |
frm-8 | Protein FRM-8 | 0.012 | |
C55B6.1 | Protein C55B6.1 | 0.012 | |
spc-1 | Protein SPC-1 | 0.011 | |
pat-3 | Protein PAT-3 | 0.011 | |
rab-30 | Protein RAB-30 | 0.011 | |
trcs-2 | Protein TRCS-2 | 0.011 | |
F09C8.2 | Protein F09C8.2 | 0.011 | |
sdpn-1 | Protein SDPN-1 | 0.011 | |
C43H6.1 | Protein C43H6.1 | 0.010 | |
zfp-3 | Protein ZFP-3 | 0.010 | |
lam-2 | Protein LAM-2 | 0.010 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
neur | neuralized | 0.938 | |
phl | pole hole | 0.907 | |
Rac1 | CG2248 gene product from transcript CG2248-RA | 0.884 | |
Shc | SHC-adaptor protein | 0.746 | |
sty | sprouty | 0.739 | |
Sos | Son of sevenless | 0.701 | |
rho | rhomboid | 0.692 | |
Rheb | CG1081 gene product from transcript CG1081-RA | 0.687 | |
Gap1 | GTPase-activating protein 1 | 0.662 | |
drk | downstream of receptor kinase | 0.644 | |
Dsor1 | Downstream of raf1 | 0.629 | |
rl | rolled | 0.575 | |
Socs36E | Suppressor of cytokine signaling at 36E | 0.547 | |
argos | CG4531 gene product from transcript CG4531-RA | 0.546 | |
Cbl | CG7037 gene product from transcript CG7037-RB | 0.539 | |
cnk | connector enhancer of ksr | 0.526 | |
cindr | CIN85 and CD2AP orthologue | 0.518 | |
ex | expanded | 0.484 | |
Vps25 | Vacuolar protein sorting 25 | 0.447 | |
sdk | sidekick | 0.431 | |
Dad | Daughters against dpp | 0.405 | |
C3G | CG42328 gene product from transcript CG42328-RC | 0.394 | |
kek1 | kekkon-1 | 0.378 | |
wts | warts | 0.377 | |
sev | sevenless | 0.367 | |
S6kII | RPS6-protein kinase-II | 0.337 | |
Pten | CG5671 gene product from transcript CG5671-RB | 0.319 | |
Gp150 | CG5820 gene product from transcript CG5820-RA | 0.315 | |
Gug | Grunge | 0.314 | |
Hrs | Hepatocyte growth factor regulated tyrosine kinase substrate | 0.305 | |
ru | roughoid | 0.289 | |
NFAT | NFAT homolog | 0.286 | |
cos | costa | 0.276 | |
Mkp3 | Mitogen-activated protein kinase phosphatase 3 | 0.270 | |
Apc | APC-like | 0.265 | |
Nedd4 | CG42279 gene product from transcript CG42279-RJ | 0.265 | |
PTP-ER | Protein tyrosine phosphatase-ERK/Enhancer of Ras1 | 0.253 | |
mp | multiplexin | 0.248 | |
dos | daughter of sevenless | 0.247 | |
Pkn | Protein kinase related to protein kinase N | 0.233 | |
ed | echinoid | 0.231 | |
hipk | homeodomain interacting protein kinase | 0.208 | |
sno | strawberry notch | 0.206 | |
babo | baboon | 0.203 | |
mask | multiple ankyrin repeats single KH domain | 0.200 | |
slmb | supernumerary limbs | 0.199 | |
Rab7 | Rab-protein 7 | 0.191 | |
ro | rough | 0.187 | |
cv | crossveinless | 0.184 | |
tan | tantalus | 0.179 | |
sbb | scribbler | 0.179 | |
aop | anterior open | 0.172 | |
Tao-1 | CG14217 gene product from transcript CG14217-RF | 0.170 | |
pnt | pointed | 0.167 | |
Wnk | CG7177 gene product from transcript CG7177-RA | 0.161 | |
Mrtf | Myocardin-related transcription factor | 0.161 | |
l(2)gd1 | lethal (2) giant discs 1 | 0.161 | |
scb | scab | 0.158 | |
Psn | Presenilin | 0.155 | |
amos | absent MD neurons and olfactory sensilla | 0.154 | |
tkv | thickveins | 0.153 | |
aux | auxillin | 0.151 | |
Nrt | Neurotactin | 0.147 | |
Pvr | PDGF- and VEGF-receptor related | 0.139 | |
sina | seven in absentia | 0.138 | |
Ten-m | Tenascin major | 0.136 | |
hpo | hippo | 0.135 | |
mop | myopic | 0.134 | |
Rab5 | Rab-protein 5 | 0.133 | |
Pvf1 | PDGF- and VEGF-related factor 1 | 0.133 | |
vav | CG7893 gene product from transcript CG7893-RB | 0.130 | |
Vps36 | Vacuolar protein sorting 36 | 0.130 | |
put | punt | 0.128 | |
Jra | Jun-related antigen | 0.127 | |
cno | canoe | 0.126 | |
ksr | kinase suppressor of ras | 0.124 | |
csw | corkscrew | 0.120 | |
Marf | Mitochondrial assembly regulatory factor | 0.120 | |
kst | karst | 0.116 | |
Mer | Merlin | 0.114 | |
egr | eiger | 0.113 | |
bin | biniou | 0.112 | |
Sema-1a | CG18405 gene product from transcript CG18405-RD | 0.108 | |
p130CAS | CG1212 gene product from transcript CG1212-RA | 0.107 | |
grk | gurken | 0.107 | |
skd | skuld | 0.106 | |
Akt1 | CG4006 gene product from transcript CG4006-RA | 0.105 | |
Ubqn | Ubiquilin | 0.105 | |
boss | bride of sevenless | 0.103 | |
vps2 | CG14542 gene product from transcript CG14542-RA | 0.101 | |
fj | four-jointed | 0.100 | |
ash2 | absent, small, or homeotic discs 2 | 0.099 | |
step | steppke | 0.098 | |
mbc | myoblast city | 0.097 | |
rg | rugose | 0.095 | |
drpr | draper | 0.095 | |
nmo | nemo | 0.095 | |
CG1021 | CG1021 gene product from transcript CG1021-RE | 0.093 | |
RagA | CG11968 gene product from transcript CG11968-RA | 0.093 | |
sv | shaven | 0.092 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.999 | |
EGFR | epidermal growth factor receptor | 0.988 | |
ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.964 | |
SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.613 | |
RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.609 | |
PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.562 | |
SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.481 | |
APP | amyloid beta (A4) precursor protein | 0.399 | |
GHR | growth hormone receptor | 0.303 | |
CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.302 | |
DLG1 | discs, large homolog 1 (Drosophila) | 0.299 | |
ERBB4 | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 0.294 | |
ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.281 | |
PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.271 | |
TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 0.245 | |
PTK2 | PTK2 protein tyrosine kinase 2 | 0.208 | |
YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.187 | |
CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.170 | |
GAB1 | GRB2-associated binding protein 1 | 0.165 | |
PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | 0.139 | |
NCOR1 | nuclear receptor corepressor 1 | 0.137 | |
ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.136 | |
UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.129 | |
DLG4 | discs, large homolog 4 (Drosophila) | 0.129 | |
PXN | paxillin | 0.126 | |
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.123 | |
DUSP1 | dual specificity phosphatase 1 | 0.122 | |
ARID1A | AT rich interactive domain 1A (SWI-like) | 0.108 | |
APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.107 | |
MUC1 | mucin 1, cell surface associated | 0.104 | |
STAMBP | STAM binding protein | 0.103 | |
PDCD6IP | programmed cell death 6 interacting protein | 0.100 | |
SPRR2A | small proline-rich protein 2A | 0.099 | |
APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | 0.096 | |
MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.096 | |
GRB2 | growth factor receptor-bound protein 2 | 0.093 | |
UBE3A | ubiquitin protein ligase E3A | 0.092 | |
PTPN23 | protein tyrosine phosphatase, non-receptor type 23 | 0.092 | |
ESR1 | estrogen receptor 1 | 0.091 | |
ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.090 | |
TSG101 | tumor susceptibility gene 101 | 0.089 | |
PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.088 | |
EZR | ezrin | 0.086 | |
RASA1 | RAS p21 protein activator (GTPase activating protein) 1 | 0.085 | |
ARHGAP1 | Rho GTPase activating protein 1 | 0.076 | |
MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.076 | |
GDA | guanine deaminase | 0.073 | |
MAP3K11 | mitogen-activated protein kinase kinase kinase 11 | 0.070 | |
LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.067 | |
ABI2 | abl-interactor 2 | 0.065 | |
DSG2 | desmoglein 2 | 0.064 | |
LAT | linker for activation of T cells | 0.062 | |
YES1 | v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 | 0.060 | |
PRKCA | protein kinase C, alpha | 0.060 | |
ARHGAP5 | Rho GTPase activating protein 5 | 0.059 | |
YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 0.059 | |
CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.058 | |
EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.058 | |
PTEN | phosphatase and tensin homolog | 0.058 | |
LTBP4 | latent transforming growth factor beta binding protein 4 | 0.056 | |
IRS1 | insulin receptor substrate 1 | 0.054 | |
CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.054 | |
CAV1 | caveolin 1, caveolae protein, 22kDa | 0.053 | |
TFF1 | trefoil factor 1 | 0.052 | |
GRN | granulin | 0.052 | |
NCK1 | NCK adaptor protein 1 | 0.051 | |
LRRK2 | leucine-rich repeat kinase 2 | 0.051 | |
NOTCH1 | notch 1 | 0.050 | |
CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.050 | |
MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.050 | |
PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.048 | |
SH3KBP1 | SH3-domain kinase binding protein 1 | 0.046 | |
CD28 | CD28 molecule | 0.045 | |
TOM1L1 | target of myb1 (chicken)-like 1 | 0.045 | |
VAV1 | vav 1 guanine nucleotide exchange factor | 0.045 | |
MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.045 | |
SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 | 0.044 | |
SH3GL3 | SH3-domain GRB2-like 3 | 0.043 | |
CAV2 | caveolin 2 | 0.043 | |
SORBS3 | sorbin and SH3 domain containing 3 | 0.043 | |
CSNK1G3 | casein kinase 1, gamma 3 | 0.042 | |
MAPK1 | mitogen-activated protein kinase 1 | 0.041 | |
PBK | PDZ binding kinase | 0.041 | |
SOS1 | son of sevenless homolog 1 (Drosophila) | 0.039 | |
SRCIN1 | SRC kinase signaling inhibitor 1 | 0.039 | |
YAP1 | Yes-associated protein 1 | 0.039 | |
CLASP1 | cytoplasmic linker associated protein 1 | 0.038 | |
MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.038 | |
RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.038 | |
GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.037 | |
FBLN1 | fibulin 1 | 0.037 | |
EPOR | erythropoietin receptor | 0.036 | |
RIN1 | Ras and Rab interactor 1 | 0.035 | |
SH2D3A | SH2 domain containing 3A | 0.035 | |
SOCS1 | suppressor of cytokine signaling 1 | 0.035 | |
PSAP | prosaposin | 0.034 | |
EPS15 | epidermal growth factor receptor pathway substrate 15 | 0.034 | |
ATN1 | atrophin 1 | 0.034 | |
HDAC4 | histone deacetylase 4 | 0.034 | |
PTPRA | protein tyrosine phosphatase, receptor type, A | 0.034 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Grb2 | growth factor receptor bound protein 2 | 0.632 | |
Sgk1 | serum/glucocorticoid regulated kinase 1 | 0.156 | |
Sirpa | signal-regulatory protein alpha | 0.148 | |
Ptpn6 | protein tyrosine phosphatase, non-receptor type 6 | 0.125 | |
Egfr | epidermal growth factor receptor | 0.125 | |
Atp6v1b2 | ATPase, H transporting, lysosomal V1 subunit B2 | 0.099 | |
Src | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.058 | |
Nsf | N-ethylmaleimide-sensitive factor | 0.057 | |
Shc1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.053 | |
Hk1 | hexokinase 1 | 0.052 | |
Litaf | lipopolysaccharide-induced TNF factor | 0.049 | |
Prkcd | protein kinase C, delta | 0.047 | |
Cd86 | CD86 molecule | 0.047 | |
Ptafr | platelet-activating factor receptor | 0.045 | |
Pfn1 | profilin 1 | 0.044 | |
Vcan | versican | 0.044 | |
Ptprs | protein tyrosine phosphatase, receptor type, S | 0.044 | |
RGD1308350 | similar to hypothetical protein MGC13251 | 0.042 | |
Grip1 | glutamate receptor interacting protein 1 | 0.042 | |
Cbl | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.041 | |
Ube2h | ubiquitin-conjugating enzyme E2H | 0.040 | |
Muc4 | mucin 4, cell surface associated | 0.040 | |
Cxcr4 | chemokine (C-X-C motif) receptor 4 | 0.039 | |
Il2rb | interleukin 2 receptor, beta | 0.039 | |
Plcg2 | phospholipase C, gamma 2 | 0.038 | |
Rin1 | Ras and Rab interactor 1 | 0.033 | |
Ppp2r1a | protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform | 0.033 | |
Pld2 | phospholipase D2 | 0.032 | |
Lcp2 | lymphocyte cytosolic protein 2 | 0.030 | |
Inpp5d | inositol polyphosphate-5-phosphatase D | 0.029 | |
Tap2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | 0.028 | |
Pitpna | phosphatidylinositol transfer protein, alpha | 0.028 | |
Ap2b1 | adaptor-related protein complex 2, beta 1 subunit | 0.027 | |
Il1a | interleukin 1 alpha | 0.027 | |
Met | met proto-oncogene | 0.027 | |
Klf9 | Kruppel-like factor 9 | 0.027 | |
Tle4 | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 0.026 | |
Stk10 | serine/threonine kinase 10 | 0.026 | |
Dab2 | disabled homolog 2 (Drosophila) | 0.026 | |
Grin2b | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.026 | |
Gfi1 | growth factor independent 1 transcription repressor | 0.025 | |
Ptprc | protein tyrosine phosphatase, receptor type, C | 0.025 | |
Pik3ap1 | phosphoinositide-3-kinase adaptor protein 1 | 0.025 | |
Fgr | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.024 | |
Ywhaz | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.023 | |
Ciita | class II, major histocompatibility complex, transactivator | 0.023 | |
Ppp3r1 | protein phosphatase 3, regulatory subunit B, alpha isoform | 0.023 | |
Tnf | tumor necrosis factor (TNF superfamily, member 2) | 0.023 | |
Foxs1 | forkhead box S1 | 0.023 | |
Bdkrb2 | bradykinin receptor B2 | 0.022 | |
Apba3 | amyloid beta (A4) precursor protein-binding, family A, member 3 | 0.022 | |
Rab21 | RAB21, member RAS oncogene family | 0.022 | |
Efhd2 | EF-hand domain family, member D2 | 0.022 | |
Ceacam10 | carcinoembryonic antigen-related cell adhesion molecule 10 | 0.022 | |
PVR | poliovirus receptor | 0.022 | |
Fmnl1 | formin-like 1 | 0.022 | |
Gpr173 | G-protein coupled receptor 173 | 0.021 | |
Gnai2 | guanine nucleotide binding protein (G protein), alpha inhibiting 2 | 0.021 | |
Lhx5 | LIM homeobox 5 | 0.021 | |
Smad1 | SMAD family member 1 | 0.021 | |
Rhoa | ras homolog gene family, member A | 0.021 | |
Grin2a | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.021 | |
Hpcal4 | hippocalcin-like 4 | 0.020 | |
Ttyh3 | tweety homolog 3 (Drosophila) | 0.020 | |
Anxa2 | annexin A2 | 0.020 | |
Grasp | GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein | 0.020 | |
Ifrd1 | interferon-related developmental regulator 1 | 0.020 | |
Ngfr | nerve growth factor receptor (TNFR superfamily, member 16) | 0.019 | |
Gata2 | GATA binding protein 2 | 0.019 | |
Agrn | agrin | 0.019 | |
Fosl2 | fos-like antigen 2 | 0.019 | |
Hnrnpab | heterogeneous nuclear ribonucleoprotein A/B | 0.019 | |
Cd38 | CD38 molecule | 0.019 | |
Cpne5 | copine V | 0.019 | |
Fgf5 | fibroblast growth factor 5 | 0.019 | |
Dchs1 | dachsous 1 (Drosophila) | 0.019 | |
Arf3 | ADP-ribosylation factor 3 | 0.019 | |
Mapre1 | microtubule-associated protein, RP/EB family, member 1 | 0.019 | |
Slc6a9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 | 0.018 | |
Irf1 | interferon regulatory factor 1 | 0.018 | |
Lyn | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.018 | |
Rab7a | RAB7A, member RAS oncogene family | 0.018 | |
F2rl1 | coagulation factor II (thrombin) receptor-like 1 | 0.018 | |
Epha2 | Eph receptor A2 | 0.018 | |
Fgd2 | FYVE, RhoGEF and PH domain containing 2 | 0.018 | |
Il2rg | interleukin 2 receptor, gamma | 0.017 | |
Sorbs1 | sorbin and SH3 domain containing 1 | 0.017 | |
Cadm1 | cell adhesion molecule 1 | 0.017 | |
Jak1 | Janus kinase 1 | 0.017 | |
Vav1 | vav 1 guanine nucleotide exchange factor | 0.017 | |
Cd37 | CD37 molecule | 0.017 | |
Pfkfb2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 | 0.016 | |
Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.016 | |
Rhob | ras homolog gene family, member B | 0.016 | |
Sash3 | SAM and SH3 domain containing 3 | 0.016 | |
Cd40 | CD40 molecule, TNF receptor superfamily member 5 | 0.016 | |
Adora2a | adenosine A2a receptor | 0.016 | |
Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.016 | |
Pxn | paxillin | 0.016 | |
Itpr3 | inositol 1,4,5-triphosphate receptor, type 3 | 0.016 |