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Process View

Drosophila melanogaster

21 genes annotated in fly

positive regulation of autophagy

Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of autophagy"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of autophagy" (in gray)

Name	Description	Probability	Func Analog Organism
Atg18	Autophagy-specific gene 18	0.998
Pi3K59F	Phosphotidylinositol 3 kinase 59F	0.943
Atg1	Autophagy-specific gene 1	0.909
S6k	RPS6-p70-protein kinase	0.839
Atg13	Autophagy-specific gene 13	0.796
Atg8a	Autophagy-specific gene 8a	0.768
Dcp-1	Death caspase-1	0.765
Atg2	Autophagy-specific gene 2	0.756
Lnk	CG17367 gene product from transcript CG17367-RC	0.695
Atg9	Autophagy-specific gene 9	0.668
Sir2	CG5216 gene product from transcript CG5216-RA	0.664	Human Mouse
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.617
car	carnation	0.589
grim	CG4345 gene product from transcript CG4345-RA	0.572
RASSF8	CG5053 gene product from transcript CG5053-RA	0.546
Mekk1	CG7717 gene product from transcript CG7717-RB	0.535
Atg7	Autophagy-specific gene 7	0.515
brat	brain tumor	0.514
spin	spinster	0.456
Sox14	Sox box protein 14	0.391
ird1	immune response deficient 1	0.354
debcl	death executioner Bcl-2 homologue	0.348
Rel	Relish	0.303
Atg4	Autophagy-specific gene 4	0.288
p38b	CG7393 gene product from transcript CG7393-RA	0.279	Fly
rpr	reaper	0.276
lok	loki	0.249
Parp	Poly-(ADP-ribose) polymerase	0.241
Akt1	CG4006 gene product from transcript CG4006-RA	0.210
chico	CG5686 gene product from transcript CG5686-RB	0.201
th	thread	0.200
ari-2	ariadne 2	0.187
yki	yorkie	0.185
wts	warts	0.176
Ice	CG7788 gene product from transcript CG7788-RA	0.174	Fly
Toll-7	CG8595 gene product from transcript CG8595-RA	0.159
Rheb	CG1081 gene product from transcript CG1081-RA	0.132
bif	bifocal	0.124
X11L	CG5675 gene product from transcript CG5675-RB	0.097
BG4	CG12297 gene product from transcript CG12297-RA	0.096
imd	immune deficiency	0.095
lmg	lemming	0.094
CG31033	CG31033 gene product from transcript CG31033-RC	0.088
egr	eiger	0.087
drpr	draper	0.087
Toll-6	CG7250 gene product from transcript CG7250-RA	0.085	Fly
NFAT	NFAT homolog	0.083
CG11877	CG11877 gene product from transcript CG11877-RA	0.082
Eip74EF	Ecdysone-induced protein 74EF	0.079
SNF4Agamma	SNF4/AMP-activated protein kinase gamma subunit	0.079
kibra	kibra ortholog	0.076
cert	ceramide transfer protein	0.069
l(3)82Fd	CG32464 gene product from transcript CG32464-RR	0.063
dve	defective proventriculus	0.059
NT1	Neurotrophin 1	0.059
AGO2	Argonaute 2	0.057
Pi3K21B	CG2699 gene product from transcript CG2699-RA	0.055
Dab	Disabled	0.055
SuUR	Suppressor of Under-Replication	0.052
gig	gigas	0.052
Mt2	Methyltransferase 2	0.051
hep	hemipterous	0.050
Ark	Apaf-1-related-killer	0.045
p53	CG33336 gene product from transcript CG33336-RB	0.045
Traf6	TNF-receptor-associated factor 6	0.045
sina	seven in absentia	0.045
Adf1	Adh transcription factor 1	0.044
Hrs	Hepatocyte growth factor regulated tyrosine kinase substrate	0.043
CG5794	CG5794 gene product from transcript CG5794-RB	0.043
Traf4	TNF-receptor-associated factor 4	0.043	Fly
CG9063	CG9063 gene product from transcript CG9063-RA	0.042
klu	klumpfuss	0.041
eyg	eyegone	0.040
Myd88	CG2078 gene product from transcript CG2078-RA	0.037
Pink1	PTEN-induced putative kinase 1	0.037
rin	rasputin	0.036
Lis-1	Lissencephaly-1	0.036
jing	CG9397 gene product from transcript CG9397-RI	0.035
Rfabg	Retinoid- and fatty acid-binding glycoprotein	0.034
Thor	CG8846 gene product from transcript CG8846-RA	0.034
Tip60	CG6121 gene product from transcript CG6121-RA	0.033
Ric	Ras which interacts with Calmodulin	0.032
Dfd	Deformed	0.032
CG1021	CG1021 gene product from transcript CG1021-RE	0.032
Rpn6	Proteasome p44.5 subunit	0.031
CG12081	CG12081 gene product from transcript CG12081-RA	0.030
Rab7	Rab-protein 7	0.030
lqfR	liquid facets-Related	0.030
CG3589	CG3589 gene product from transcript CG3589-RA	0.030
sim	single-minded	0.029	Fly
RhoGAP68F	CG6811 gene product from transcript CG6811-RA	0.028
sra	sarah	0.026
Parg	Poly(ADP-ribose) glycohydrolase	0.026
CG18754	CG18754 gene product from transcript CG18754-RB	0.026
TORC	CG6064 gene product from transcript CG6064-RA	0.025
CG11534	CG11534 gene product from transcript CG11534-RA	0.025
Eip93F	CG18389 gene product from transcript CG18389-RB	0.025
Rac1	CG2248 gene product from transcript CG2248-RA	0.025
trio	CG18214 gene product from transcript CG18214-RA	0.024
Syx17	Syntaxin 17	0.024
Mer	Merlin	0.024
trpml	transient receptor potential mucolipin	0.024
CG10277	CG10277 gene product from transcript CG10277-RB	0.024
shark	Src homology 2, ankyrin repeat, tyrosine kinase	0.024
CG6734	CG6734 gene product from transcript CG6734-RA	0.023
Stam	Signal transducing adaptor molecule	0.022
cathD	CG1548 gene product from transcript CG1548-RA	0.021
CG8155	CG8155 gene product from transcript CG8155-RA	0.021
CG11242	CG11242 gene product from transcript CG11242-RA	0.021
Smg5	CG8954 gene product from transcript CG8954-RA	0.021
Mnt	CG13316 gene product from transcript CG13316-RD	0.020
spas	spastin	0.019
Nc	Nedd2-like caspase	0.019	Fly
CG18005	CG18005 gene product from transcript CG18005-RA	0.019
Myo31DF	Myosin 31DF	0.019
l(3)05822	lethal (3) 05822	0.018
dm	diminutive	0.018
CG3573	CG3573 gene product from transcript CG3573-RA	0.018
Su(var)3-7	Suppressor of variegation 3-7	0.018
rk	rickets	0.018
Hcf	Host cell factor	0.018
Kr-h1	Kruppel homolog 1	0.018
crp	cropped	0.017
Atf-2	Activating transcription factor-2	0.017
Atg6	Autophagy-specific gene 6	0.016
Sep4	Septin 4	0.016
CG1347	CG1347 gene product from transcript CG1347-RB	0.016
Met	Methoprene-tolerant	0.016
pr-set7	CG3307 gene product from transcript CG3307-RC	0.016
jeb	jelly belly	0.016
Gyc76C	Guanylyl cyclase at 76C	0.016
PRL-1	CG4993 gene product from transcript CG4993-RB	0.016
Duox	Dual oxidase	0.015
Pak	PAK-kinase	0.015
CG9866	CG9866 gene product from transcript CG9866-RA	0.015
Gef26	CG9491 gene product from transcript CG9491-RB	0.015
Rab2	Rab-protein 2	0.015
ImpL2	Ecdysone-inducible gene L2	0.015
SH3PX1	CG6757 gene product from transcript CG6757-RA	0.015
Trim9	CG31721 gene product from transcript CG31721-RB	0.015
MESR6	Misexpression suppressor of ras 6	0.015
Nipped-B	CG17704 gene product from transcript CG17704-RI	0.015
skl	sickle	0.014
CaMKII	Calcium/calmodulin-dependent protein kinase II	0.014
CG4495	CG4495 gene product from transcript CG4495-RA	0.014
edl	ETS-domain lacking	0.014
deltaCOP	delta-coatomer protein	0.013
CG7158	CG7158 gene product from transcript CG7158-RA	0.013
Marf	Mitochondrial assembly regulatory factor	0.013
melt	melted	0.013
egg	eggless	0.013
Pngl	PNGase-like	0.013
cpa	capping protein alpha	0.013
pirk	poor Imd response upon knock-in	0.013
CG17273	CG17273 gene product from transcript CG17273-RA	0.013
dsx	doublesex	0.013
PP2A-B'	CG7913 gene product from transcript CG7913-RK	0.013
Ppt1	Palmitoyl-protein thioesterase 1	0.013
wun2	wunen-2	0.012
synj	synaptojanin	0.012
Klp68D	Kinesin-like protein at 68D	0.012
CG11347	CG11347 gene product from transcript CG11347-RE	0.012
Notum	CG13076 gene product from transcript CG13076-RB	0.012
fend	forked end	0.012
CG14869	CG14869 gene product from transcript CG14869-RB	0.012
Adar	Adenosine deaminase acting on RNA	0.012
Pka-C1	cAMP-dependent protein kinase 1	0.012
plu	plutonium	0.012
HDAC6	CG6170 gene product from transcript CG6170-RA	0.012
CG42256	CG42256 gene product from transcript CG42256-RH	0.012
Pc	Polycomb	0.012
nimC4	nimrod C4	0.012
toy	twin of eyeless	0.012
Eip71CD	Ecdysone-induced protein 28/29kD	0.012
rno	rhinoceros	0.012
kuz	kuzbanian	0.011
Ilk	Integrin linked kinase	0.011
pie	pineapple eye	0.011
CG12207	CG12207 gene product from transcript CG12207-RB	0.011
ptr	proximal to raf	0.011
CG17746	CG17746 gene product from transcript CG17746-RA	0.011
S6kII	RPS6-protein kinase-II	0.011	Fly
Pk61C	Protein kinase 61C	0.011
lab	labial	0.010
CG8481	CG8481 gene product from transcript CG8481-RB	0.010
PSR	phosphatidylserine receptor	0.010
Ptp61F	Protein tyrosine phosphatase 61F	0.010
dnr1	defense repressor 1	0.010
bchs	blue cheese	0.010	Human
NLaz	Neural Lazarillo	0.010
Ilp2	Insulin-like peptide 2	0.010
Vps4	Vacuolar protein sorting 4	0.010
Irk3	Inwardly rectifying potassium channel 3	0.010
caz	cabeza	0.010
chrb	charybde	0.010