IMP

Process View

Drosophila melanogaster

28 genes annotated in fly

synaptic vesicle endocytosis

An endocytosis process that results in the invagination of the axonal plasma membrane to create a membrane-bounded vesicle. This process takes up excess membrane that would otherwise accumulate at the presynaptic terminal due to fusion of vesicle membranes during neurotransmitter release. The vesicles created may subsequently be used for neurotransmitter storage and release.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in fly Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "synaptic vesicle endocytosis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "synaptic vesicle endocytosis" (in gray)

Name	Description	Probability	Func Analog Organism
Dap160	Dynamin associated protein 160	0.995
lap	like-AP180	0.979
Snap25	Synapse protein 25	0.975
GluRIIA	Glutamate receptor IIA	0.949
Syt1	Synaptotagmin 1	0.912
hiw	highwire	0.907
brp	bruchpilot	0.889
wit	wishful thinking	0.861
unc-104	CG8566 gene product from transcript CG8566-RB	0.840
stj	straightjacket	0.826
Ext2	CG8433 gene product from transcript CG8433-RA	0.799	Fly
endoA	endophilin A	0.775
dys	dysfusion	0.769
comt	comatose	0.767
nwk	nervous wreck	0.764
Csp	Cysteine string protein	0.760
HDAC6	CG6170 gene product from transcript CG6170-RA	0.694
PP2A-B'	CG7913 gene product from transcript CG7913-RK	0.693
cpx	complexin	0.692
dlg1	discs large 1	0.653	Mouse
CaMKII	Calcium/calmodulin-dependent protein kinase II	0.619
stnA	stoned A	0.606
Smg1	CG32743 gene product from transcript CG32743-RA	0.590
rtGEF	rho-type guanine exchange factor	0.543
sgl	sugarless	0.532
Syt4	Synaptotagmin 4	0.504
hk	hook	0.470
Nrx-1	Neurexin 1	0.448
WASp	CG1520 gene product from transcript CG1520-RA	0.442
TBPH	CG10327 gene product from transcript CG10327-RC	0.436
Syx1A	Syntaxin 1A	0.428
cac	cacophony	0.386
pAbp	polyA-binding protein	0.349
mnb	minibrain	0.339
CG9339	CG9339 gene product from transcript CG9339-RG	0.339
yrt	yurt	0.337
Arp66B	Actin-related protein 66B	0.327
beta-Spec	beta Spectrin	0.315
stnB	stoned B	0.309
RhoGAP92B	CG4755 gene product from transcript CG4755-RA	0.301
spas	spastin	0.288
sei	seizure	0.286
stmA	stambha A	0.269
Rab5	Rab-protein 5	0.238
jeb	jelly belly	0.236
synj	synaptojanin	0.225
Snap	Soluble NSF attachment protein	0.221
Mob4	CG3403 gene product from transcript CG3403-RA	0.208
n-syb	n-synaptobrevin	0.194
Ank2	Ankyrin 2	0.188
sax	saxophone	0.174
VGlut	Vesicular glutamate transporter	0.165
neuroligin	CG13772 gene product from transcript CG13772-RA	0.155	Mouse Rat
Dab	Disabled	0.149
mle	maleless	0.140
Imp	IGF-II mRNA-binding protein	0.131
stai	stathmin	0.106
dlp	dally-like	0.106
Fak56D	Focal Adhesion Kinase	0.105
CrebB-17A	Cyclic-AMP response element binding protein B at 17A	0.104
Sbf	SET domain binding factor	0.103
unc-13	CG2999 gene product from transcript CG2999-RA	0.100	Mouse
wnd	wallenda	0.088
Liprin-alpha	CG11199 gene product from transcript CG11199-RB	0.085
CG12753	CG12753 gene product from transcript CG12753-RB	0.081
heph	hephaestus	0.081
Gad1	Glutamic acid decarboxylase 1	0.078
Eps-15	Epidermal growth factor receptor pathway substrate clone 15	0.077
CG12187	CG12187 gene product from transcript CG12187-RA	0.076
rut	rutabaga	0.075
kcc	kazachoc	0.074
syd	sunday driver	0.070
CG43073	CG43073 gene product from transcript CG43073-RF	0.069
Lrrk	Leucine-rich repeat kinase	0.069
Takr99D	Tachykinin-like receptor at 99D	0.067
botv	brother of tout-velu	0.065	Fly
KaiRIA	CG18039 gene product from transcript CG18039-RA	0.064
Adar	Adenosine deaminase acting on RNA	0.062
capt	capulet	0.061
Khc	Kinesin heavy chain	0.060
Plc21C	Phospholipase C at 21C	0.060
Letm1	CG4589 gene product from transcript CG4589-RB	0.060
CDase	Ceramidase	0.058
dnc	dunce	0.056
l(2)k16918	lethal (2) k16918	0.055
hig	hikaru genki	0.055
Atpalpha	Na pump alpha subunit	0.052
Alk	CG8250 gene product from transcript CG8250-RA	0.051
nompC	no mechanoreceptor potential C	0.048
tweek	CG42555 gene product from transcript CG42555-RD	0.047
Vmat	Vesicular monoamine transporter	0.047
Frq1	Frequenin 1	0.047
faf	fat facets	0.045
slmb	supernumerary limbs	0.044
Caki	Calcium/calmodulin-dependent protein kinase	0.043
GluRIIB	Glutamate receptor IIB	0.037
scb	scab	0.036
spict	spichthyin	0.035
CkIalpha	Casein kinase Ialpha	0.035
par-1	CG8201 gene product from transcript CG8201-RA	0.035
CCKLR-17D1	CCK-like receptor at 17D1	0.033
tacc	transforming acidic coiled-coil protein	0.033
Vap-33-1	CG5014 gene product from transcript CG5014-RB	0.032
CG31146	CG31146 gene product from transcript CG31146-RD	0.032	Rat
nudE	CG8104 gene product from transcript CG8104-RB	0.031
trpml	transient receptor potential mucolipin	0.031
Dsk	Drosulfakinin	0.030
Frq2	Frequenin 2	0.030
lkb1	CG9374 gene product from transcript CG9374-RJ	0.030
G-oalpha47A	G protein oalpha 47A	0.030
lat	latheo	0.028
Galpha49B	G protein alpha49B	0.028
alpha-Spec	alpha Spectrin	0.027
Atg1	Autophagy-specific gene 1	0.026
simj	simjang	0.025
ewg	erect wing	0.025
Atx2	Ataxin-2	0.025
CG32635	CG32635 gene product from transcript CG32635-RA	0.024
fd85E	forkhead domain 85E	0.024
ple	pale	0.024
sif	still life	0.023
Nsf2	NEM-sensitive fusion protein 2	0.022
Syx18	Syntaxin 18	0.022
Chc	Clathrin heavy chain	0.022
slo	slowpoke	0.022
Sema-1a	CG18405 gene product from transcript CG18405-RD	0.022
bdg	bedraggled	0.022
GluRIIE	Glutamate receptor IIE	0.021
Cdk5alpha	Cdk5 activator-like protein	0.021
mGluRA	metabotropic glutamate receptor	0.020
Dad	Daughters against dpp	0.020
Hip14	Huntingtin-interacting protein 14	0.019
EloA	Elongin A	0.019
Gug	Grunge	0.019
TER94	CG2331 gene product from transcript CG2331-RA	0.019
synaptogyrin	CG10808 gene product from transcript CG10808-RA	0.018
Rbsn-5	Rabenosyn-5	0.018
Ggamma1	G protein gamma 1	0.018
sas-6	spindle assembly abnormal 6	0.018
TyrR	Tyramine receptor	0.018
VAChT	CG32848 gene product from transcript CG32848-RA	0.018
Atx-1	Ataxin 1	0.017
Ranbp11	CG33139 gene product from transcript CG33139-RA	0.017
sec5	CG8843 gene product from transcript CG8843-RA	0.017
sec71	CG7578 gene product from transcript CG7578-RA	0.017
CanA-14F	Calcineurin A at 14F	0.017
wee	CG4488 gene product from transcript CG4488-RA	0.016
CG10260	CG10260 gene product from transcript CG10260-RB	0.016
AdoR	Adenosine receptor	0.016
CkIIalpha	Casein kinase II alpha subunit	0.016
Cyp303a1	CG4163 gene product from transcript CG4163-RA	0.016
egl	egalitarian	0.015
CG4030	CG4030 gene product from transcript CG4030-RA	0.015
poe	purity of essence	0.015
Prosalpha1	Proteasome alpha1 subunit	0.015
loqs	loquacious	0.015
Aats-met	Methionyl-tRNA synthetase	0.015
Lis-1	Lissencephaly-1	0.014
gbb	glass bottom boat	0.014
Nrg	Neuroglian	0.014
GluRIIC	Glutamate receptor IIC	0.014
skf	skiff	0.014
Rab3	Rab-protein 3	0.014	Mouse
CG7023	CG7023 gene product from transcript CG7023-RB	0.014
Vha100-1	CG1709 gene product from transcript CG1709-RF	0.014
Gprk1	G protein-coupled receptor kinase 1	0.013
DAAM	Dishevelled Associated Activator of Morphogenesis	0.013
toc	toucan	0.013
Dhc64C	Dynein heavy chain 64C	0.013
Khc-73	Kinesin-73	0.013	Fly
Asator	CG11533 gene product from transcript CG11533-RF	0.013
Caps	Calcium activated protein for secretion	0.013
mol	moladietz	0.013
Oli	Olig family	0.013
Miro	Mitochondrial Rho	0.013
tefu	telomere fusion	0.013
milt	milton	0.013
Rab6	Rab-protein 6	0.012
Ppt1	Palmitoyl-protein thioesterase 1	0.012
kkv	krotzkopf verkehrt	0.012
CG9384	CG9384 gene product from transcript CG9384-RA	0.012
Sos	Son of sevenless	0.012
CG34372	CG34372 gene product from transcript CG34372-RC	0.012
Rfx	CG6312 gene product from transcript CG6312-RA	0.012
sm	smooth	0.011
cnk	connector enhancer of ksr	0.011
trbd	trabid	0.011
CG12026	CG12026 gene product from transcript CG12026-RB	0.011
rnh1	ribonuclease H1	0.011
kuz	kuzbanian	0.011
Topors	Topoisomerase I-interacting protein	0.011
p53	CG33336 gene product from transcript CG33336-RB	0.011
pex1	peroxin 1	0.011
CG13073	CG13073 gene product from transcript CG13073-RB	0.011
CG34360	CG34360 gene product from transcript CG34360-RA	0.011
CG9139	CG9139 gene product from transcript CG9139-RA	0.011
Tbh	Tyramine beta hydroxylase	0.011
CG17086	CG17086 gene product from transcript CG17086-RA	0.011
por	porcupine	0.011
CG12001	CG12001 gene product from transcript CG12001-RA	0.010
CG32486	CG32486 gene product from transcript CG32486-RD	0.010
mib2	mind bomb 2	0.010
CG33558	CG33558 gene product from transcript CG33558-RG	0.010
mth	methuselah	0.010
Ace	Acetylcholine esterase	0.010
Arp87C	Actin-related protein 87C	0.010
ksr	kinase suppressor of ras	0.010
Ant2	Adenine nucleotide translocase 2	0.010
CG8455	CG8455 gene product from transcript CG8455-RA	0.010
CG9063	CG9063 gene product from transcript CG9063-RA	0.010
shrb	shrub	0.010
wts	warts	0.010
disp	dispatched	0.010
Kap3	Kinesin associated protein 3	0.010
Syn1	Syntrophin-like 1	0.010