IMP

Process View

Homo sapiens

31 genes annotated in human

carbohydrate homeostasis

A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "carbohydrate homeostasis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "carbohydrate homeostasis" (in gray)

Name	Description	Probability	Func Analog Organism
DAXX	death-domain associated protein	0.773
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.333
PKM2	pyruvate kinase, muscle	0.301
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.289
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.273
SLC2A3	solute carrier family 2 (facilitated glucose transporter), member 3	0.234	Human
EGFR	epidermal growth factor receptor	0.232
IL1R1	interleukin 1 receptor, type I	0.229	Rat
SLC2A14	solute carrier family 2 (facilitated glucose transporter), member 14	0.216	Human
AR	androgen receptor	0.203
SNAP23	synaptosomal-associated protein, 23kDa	0.182
CCNY	cyclin Y	0.177
TTR	transthyretin	0.170
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.169
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.150
PML	promyelocytic leukemia	0.149
OASL	2'-5'-oligoadenylate synthetase-like	0.146	Human
HLA-DMA	major histocompatibility complex, class II, DM alpha	0.141
MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	0.138
CRHR1	corticotropin releasing hormone receptor 1	0.138
IL1B	interleukin 1, beta	0.128	Rat
CREBBP	CREB binding protein	0.118
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.116
AXL	AXL receptor tyrosine kinase	0.112
PLAUR	plasminogen activator, urokinase receptor	0.110
GHR	growth hormone receptor	0.106
SMAD3	SMAD family member 3	0.102
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	0.101
RARA	retinoic acid receptor, alpha	0.098
PTEN	phosphatase and tensin homolog	0.084
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.083
NCOR1	nuclear receptor corepressor 1	0.072
NCOR2	nuclear receptor corepressor 2	0.066	Mouse
HDAC3	histone deacetylase 3	0.062
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.061
RANBP9	RAN binding protein 9	0.060
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.059
MPDZ	multiple PDZ domain protein	0.059
GRB10	growth factor receptor-bound protein 10	0.058
VAMP3	vesicle-associated membrane protein 3 (cellubrevin)	0.057
OAS1	2',5'-oligoadenylate synthetase 1, 40/46kDa	0.057
PSEN2	presenilin 2 (Alzheimer disease 4)	0.055
MYD88	myeloid differentiation primary response gene (88)	0.054
MT1A	metallothionein 1A	0.054
VCP	valosin containing protein	0.053
PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.050
IL1RAP	interleukin 1 receptor accessory protein	0.048
IL1RN	interleukin 1 receptor antagonist	0.048
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.047
SMAD2	SMAD family member 2	0.047
OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	0.046	Human
GRB2	growth factor receptor-bound protein 2	0.045
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.044
HNF1A	HNF1 homeobox A	0.044
ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.043
MIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	0.041
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.041
STAT2	signal transducer and activator of transcription 2, 113kDa	0.038
SNAP25	synaptosomal-associated protein, 25kDa	0.038
STRADA	STE20-related kinase adaptor alpha	0.037
PPARA	peroxisome proliferator-activated receptor alpha	0.037	Human
ULK1	unc-51-like kinase 1 (C. elegans)	0.036
RNASE4	ribonuclease, RNase A family, 4	0.036
MAPK6	mitogen-activated protein kinase 6	0.035
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.034
CCND3	cyclin D3	0.033
STAT5A	signal transducer and activator of transcription 5A	0.033
APC	adenomatous polyposis coli	0.032
IL6R	interleukin 6 receptor	0.032
PLAT	plasminogen activator, tissue	0.032
OAS3	2'-5'-oligoadenylate synthetase 3, 100kDa	0.032	Human
UBQLN1	ubiquilin 1	0.031
ONECUT1	one cut homeobox 1	0.031
IRF2	interferon regulatory factor 2	0.030
GAPDH	glyceraldehyde-3-phosphate dehydrogenase	0.029
LDHA	lactate dehydrogenase A	0.028
C16orf75	chromosome 16 open reading frame 75	0.028
HNF4A	hepatocyte nuclear factor 4, alpha	0.027	Mouse
HLA-DPB1	major histocompatibility complex, class II, DP beta 1	0.027
ESR1	estrogen receptor 1	0.027
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.027
IRS1	insulin receptor substrate 1	0.026
KAT2B	K(lysine) acetyltransferase 2B	0.026
CDX2	caudal type homeobox 2	0.026
PSEN1	presenilin 1	0.026
TBX5	T-box 5	0.025
ARRB2	arrestin, beta 2	0.025
RXRB	retinoid X receptor, beta	0.025
AKAP9	A kinase (PRKA) anchor protein (yotiao) 9	0.024
HNF1B	HNF1 homeobox B	0.024	Human
MGEA5	meningioma expressed antigen 5 (hyaluronidase)	0.024
PROX1	prospero homeobox 1	0.024
MX2	myxovirus (influenza virus) resistance 2 (mouse)	0.024
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.024
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.024
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.024
PDX1	pancreatic and duodenal homeobox 1	0.023	Mouse
TP53	tumor protein p53	0.023
HLA-DRB1	major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1	0.023
BTRC	beta-transducin repeat containing	0.023
HLA-B	major histocompatibility complex, class I, B	0.023
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.023
MKL1	megakaryoblastic leukemia (translocation) 1	0.023
RUSC2	RUN and SH3 domain containing 2	0.022
ALDOA	aldolase A, fructose-bisphosphate	0.022
FHL2	four and a half LIM domains 2	0.022
S100B	S100 calcium binding protein B	0.022
TRIM14	tripartite motif containing 14	0.022
RUNX1	runt-related transcription factor 1	0.022
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.022
RGS20	regulator of G-protein signaling 20	0.021
NEUROD1	neurogenic differentiation 1	0.021	Mouse Rat
IPO13	importin 13	0.021
STMN2	stathmin-like 2	0.021
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.021
ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.021
ENO1	enolase 1, (alpha)	0.021
CDK6	cyclin-dependent kinase 6	0.021
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.020
HLA-A	major histocompatibility complex, class I, A	0.020
HLA-DRB5	major histocompatibility complex, class II, DR beta 5	0.020	Human
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.020	Human
HSPA13	heat shock protein 70kDa family, member 13	0.020
GCG	glucagon	0.019
AKAP11	A kinase (PRKA) anchor protein 11	0.019
GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	0.019
ITGB1BP3	integrin beta 1 binding protein 3	0.019
TPI1	triosephosphate isomerase 1	0.019
TDGF1	teratocarcinoma-derived growth factor 1	0.019
TRIM21	tripartite motif containing 21	0.019
RYR2	ryanodine receptor 2 (cardiac)	0.019
PLSCR1	phospholipid scramblase 1	0.019
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.018
MATR3	matrin 3	0.018
ICAM1	intercellular adhesion molecule 1	0.018	Mouse
GSK3B	glycogen synthase kinase 3 beta	0.018
NKX6-1	NK6 homeobox 1	0.018
SSTR3	somatostatin receptor 3	0.018
ATN1	atrophin 1	0.018
PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.018
HIC1	hypermethylated in cancer 1	0.017
BCL6	B-cell CLL/lymphoma 6	0.017
RAB8B	RAB8B, member RAS oncogene family	0.017
RCC1	regulator of chromosome condensation 1	0.017
IL8	interleukin 8	0.017
INCENP	inner centromere protein antigens 135/155kDa	0.017
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.016
IFI30	interferon, gamma-inducible protein 30	0.016
GCKR	glucokinase (hexokinase 4) regulator	0.016
XAF1	XIAP associated factor 1	0.016
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.016
HOXD12	homeobox D12	0.016
PAH	phenylalanine hydroxylase	0.016
LAT	linker for activation of T cells	0.016
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.016
RPS3	ribosomal protein S3	0.016
PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	0.016
GJA1	gap junction protein, alpha 1, 43kDa	0.016
CXCL10	chemokine (C-X-C motif) ligand 10	0.016
FOXA2	forkhead box A2	0.016	Mouse
FRS2	fibroblast growth factor receptor substrate 2	0.016
PPP3R1	protein phosphatase 3, regulatory subunit B, alpha	0.016
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.016
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.016
PGR	progesterone receptor	0.016
PIM1	pim-1 oncogene	0.015
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.015
ENG	endoglin	0.015
IRS2	insulin receptor substrate 2	0.015
GNA13	guanine nucleotide binding protein (G protein), alpha 13	0.015
SP110	SP110 nuclear body protein	0.015
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.015
BLM	Bloom syndrome, RecQ helicase-like	0.015
CAPN1	calpain 1, (mu/I) large subunit	0.015
IFI27	interferon, alpha-inducible protein 27	0.015
BCL2	B-cell CLL/lymphoma 2	0.015
PYY	peptide YY	0.015
IGF2R	insulin-like growth factor 2 receptor	0.015
STRADB	STE20-related kinase adaptor beta	0.015
BHLHE40	basic helix-loop-helix family, member e40	0.015
OCRL	oculocerebrorenal syndrome of Lowe	0.014
CREBZF	CREB/ATF bZIP transcription factor	0.014
FOXO3	forkhead box O3	0.014	Mouse Fly
GOLGA2	golgin A2	0.014
PECAM1	platelet/endothelial cell adhesion molecule	0.014
GJD2	gap junction protein, delta 2, 36kDa	0.014
TAT	tyrosine aminotransferase	0.014
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.014	Mouse Rat
IFIT1	interferon-induced protein with tetratricopeptide repeats 1	0.013
IGFBP5	insulin-like growth factor binding protein 5	0.013	Mouse
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.013
BCR	breakpoint cluster region	0.013
ACACA	acetyl-CoA carboxylase alpha	0.013
CAV1	caveolin 1, caveolae protein, 22kDa	0.013
IRF7	interferon regulatory factor 7	0.013
KIF5B	kinesin family member 5B	0.013
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B	0.013	Human
UPP1	uridine phosphorylase 1	0.013
BCAR1	breast cancer anti-estrogen resistance 1	0.013
TNP2	transition protein 2 (during histone to protamine replacement)	0.013
OCLN	occludin	0.013
FGF8	fibroblast growth factor 8 (androgen-induced)	0.013
ARRDC3	arrestin domain containing 3	0.013
IFI44L	interferon-induced protein 44-like	0.013
IFI44	interferon-induced protein 44	0.013
CAPRIN2	caprin family member 2	0.013
BAP1	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)	0.013
GET4	golgi to ER traffic protein 4 homolog (S. cerevisiae)	0.013
CAB39	calcium binding protein 39	0.013
MSN	moesin	0.012
S100A1	S100 calcium binding protein A1	0.012
PAX4	paired box 4	0.012	Human
NKX2-2	NK2 homeobox 2	0.012
GPR6	G protein-coupled receptor 6	0.012
EGLN3	egl nine homolog 3 (C. elegans)	0.012
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.012
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.012
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.012
CSNK1A1	casein kinase 1, alpha 1	0.012
HR	hairless homolog (mouse)	0.012
UBR5	ubiquitin protein ligase E3 component n-recognin 5	0.012
MX1	myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)	0.012
SIRT1	sirtuin 1	0.012	Mouse
PAX6	paired box 6	0.012
PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	0.012	Mouse
MYOD1	myogenic differentiation 1	0.012
PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta	0.012
ITGA1	integrin, alpha 1	0.012
HLA-DMB	major histocompatibility complex, class II, DM beta	0.012
GABARAPL1	GABA(A) receptor-associated protein like 1	0.012
SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1	0.012
LTK	leukocyte receptor tyrosine kinase	0.012	Human
CACNA1B	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.012
TOP3A	topoisomerase (DNA) III alpha	0.012
MYB	v-myb myeloblastosis viral oncogene homolog (avian)	0.012
EPSTI1	epithelial stromal interaction 1 (breast)	0.012
HSD3B7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.012
G6PC2	glucose-6-phosphatase, catalytic, 2	0.012
RBP4	retinol binding protein 4, plasma	0.012
EPOR	erythropoietin receptor	0.012
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.011	Rat
KRT8	keratin 8	0.011
PRKAG1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.011
IRF9	interferon regulatory factor 9	0.011
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.011
AGPAT1	1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)	0.011
CXCL12	chemokine (C-X-C motif) ligand 12	0.011
IFIT2	interferon-induced protein with tetratricopeptide repeats 2	0.011
EIF3D	eukaryotic translation initiation factor 3, subunit D	0.011
APOL1	apolipoprotein L, 1	0.011
SYT13	synaptotagmin XIII	0.011
SETDB1	SET domain, bifurcated 1	0.011
HBG1	hemoglobin, gamma A	0.011
ARID4B	AT rich interactive domain 4B (RBP1-like)	0.011
PPP4R2	protein phosphatase 4, regulatory subunit 2	0.011
IGFBP1	insulin-like growth factor binding protein 1	0.011
CFLAR	CASP8 and FADD-like apoptosis regulator	0.011
INSR	insulin receptor	0.011
IFI6	interferon, alpha-inducible protein 6	0.011
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.011
AHCY	adenosylhomocysteinase	0.011
VTN	vitronectin	0.011
CXCL11	chemokine (C-X-C motif) ligand 11	0.011
PPY	pancreatic polypeptide	0.011
PRDX1	peroxiredoxin 1	0.011
NCOA6	nuclear receptor coactivator 6	0.011
MAPK10	mitogen-activated protein kinase 10	0.011
HPD	4-hydroxyphenylpyruvate dioxygenase	0.011
APOL6	apolipoprotein L, 6	0.011
MASP2	mannan-binding lectin serine peptidase 2	0.011
PON1	paraoxonase 1	0.011
APOA1	apolipoprotein A-I	0.011
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.011
HIST2H2AB	histone cluster 2, H2ab	0.011
MAP2K4	mitogen-activated protein kinase kinase 4	0.011
IRF1	interferon regulatory factor 1	0.011
RSAD2	radical S-adenosyl methionine domain containing 2	0.011
MTNR1B	melatonin receptor 1B	0.011
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.011
SOD2	superoxide dismutase 2, mitochondrial	0.011
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.011
PGK1	phosphoglycerate kinase 1	0.011
WDYHV1	WDYHV motif containing 1	0.011
ATG13	ATG13 autophagy related 13 homolog (S. cerevisiae)	0.011
MAPT	microtubule-associated protein tau	0.011
IMPDH2	IMP (inosine 5'-monophosphate) dehydrogenase 2	0.011
EEF2	eukaryotic translation elongation factor 2	0.011
PNLIPRP1	pancreatic lipase-related protein 1	0.011
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.011
DAB2IP	DAB2 interacting protein	0.011
MT3	metallothionein 3	0.011
CBLB	Cas-Br-M (murine) ecotropic retroviral transforming sequence b	0.010
GYS1	glycogen synthase 1 (muscle)	0.010
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.010
CCL20	chemokine (C-C motif) ligand 20	0.010
GOLGA8B	golgin A8 family, member B	0.010
ANGPTL4	angiopoietin-like 4	0.010
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.010
IGFBP3	insulin-like growth factor binding protein 3	0.010
SCGN	secretagogin, EF-hand calcium binding protein	0.010
ZFYVE9	zinc finger, FYVE domain containing 9	0.010
GAB1	GRB2-associated binding protein 1	0.010
CREB1	cAMP responsive element binding protein 1	0.010
STAT5B	signal transducer and activator of transcription 5B	0.010
TRIB3	tribbles homolog 3 (Drosophila)	0.010
SCNN1G	sodium channel, nonvoltage-gated 1, gamma	0.010
GABARAPL2	GABA(A) receptor-associated protein-like 2	0.010
TTPA	tocopherol (alpha) transfer protein	0.010
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.010