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Homo sapiens

32 genes annotated in human

Multi-species View

regulation of fibroblast proliferation

GO:0048145

Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of fibroblast proliferation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of fibroblast proliferation" (in gray)

Name	Description	Probability	Func Analog Organism
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.992
CDK2	cyclin-dependent kinase 2	0.972
RING1	ring finger protein 1	0.942
RB1	retinoblastoma 1	0.932
E2F1	E2F transcription factor 1	0.895
NAMPT	nicotinamide phosphoribosyltransferase	0.694
VEGFA	vascular endothelial growth factor A	0.589	Human
AXL	AXL receptor tyrosine kinase	0.475
RNF2	ring finger protein 2	0.453
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.424	Human Rat
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.346
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.312
RBL2	retinoblastoma-like 2 (p130)	0.286
TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)	0.281
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.276
APLF	aprataxin and PNKP like factor	0.270
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.263
GAPDH	glyceraldehyde-3-phosphate dehydrogenase	0.256
TFDP1	transcription factor Dp-1	0.247
DTX3L	deltex 3-like (Drosophila)	0.237
CCNE1	cyclin E1	0.232
CBX8	chromobox homolog 8	0.223
CCND1	cyclin D1	0.222
NRP1	neuropilin 1	0.193
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.187
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.184
CDK6	cyclin-dependent kinase 6	0.155
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.154	Human
PARP14	poly (ADP-ribose) polymerase family, member 14	0.151	Human
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.143
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.140
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.137
RBBP8	retinoblastoma binding protein 8	0.130
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.128
E2F4	E2F transcription factor 4, p107/p130-binding	0.125	Human
IGF2R	insulin-like growth factor 2 receptor	0.105
CKS1B	CDC28 protein kinase regulatory subunit 1B	0.093
TP53	tumor protein p53	0.090
CBX7	chromobox homolog 7	0.085
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.085
CBX6	chromobox homolog 6	0.085
XRCC4	X-ray repair complementing defective repair in Chinese hamster cells 4	0.083	Mouse
PGF	placental growth factor	0.081	Human
PARP9	poly (ADP-ribose) polymerase family, member 9	0.078	Human
PLAUR	plasminogen activator, urokinase receptor	0.071
BMI1	BMI1 polycomb ring finger oncogene	0.068
CCND2	cyclin D2	0.068
EGFR	epidermal growth factor receptor	0.067
MAX	MYC associated factor X	0.065
LIN9	lin-9 homolog (C. elegans)	0.059
CCND3	cyclin D3	0.056
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.054	Human
TFF1	trefoil factor 1	0.053
LIG4	ligase IV, DNA, ATP-dependent	0.051	Mouse
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.048
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.047
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.046
SKP2	S-phase kinase-associated protein 2 (p45)	0.046
RYBP	RING1 and YY1 binding protein	0.045
PLAT	plasminogen activator, tissue	0.043
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.042
RBL1	retinoblastoma-like 1 (p107)	0.042
PDGFA	platelet-derived growth factor alpha polypeptide	0.041
ALDOA	aldolase A, fructose-bisphosphate	0.040
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.039
KLF6	Kruppel-like factor 6	0.039
CCNA2	cyclin A2	0.039
LGALS8	lectin, galactoside-binding, soluble, 8	0.038
ENO1	enolase 1, (alpha)	0.038
LIN54	lin-54 homolog (C. elegans)	0.037
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.037
PLAU	plasminogen activator, urokinase	0.036
SKIL	SKI-like oncogene	0.036
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.035
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.035
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.035
RXRA	retinoid X receptor, alpha	0.032
JUNB	jun B proto-oncogene	0.031
KRT5	keratin 5	0.030
PNKP	polynucleotide kinase 3'-phosphatase	0.030
STAT1	signal transducer and activator of transcription 1, 91kDa	0.030
FZD1	frizzled homolog 1 (Drosophila)	0.030
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.028
E2F3	E2F transcription factor 3	0.028	Human
PGK1	phosphoglycerate kinase 1	0.028
CTSB	cathepsin B	0.028
BCL3	B-cell CLL/lymphoma 3	0.027
NFIL3	nuclear factor, interleukin 3 regulated	0.027
RNF144B	ring finger protein 144B	0.027
UBE2B	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	0.027
IGFBP5	insulin-like growth factor binding protein 5	0.026
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.026
CDK4	cyclin-dependent kinase 4	0.026
CXCR4	chemokine (C-X-C motif) receptor 4	0.026
MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	0.026
COL11A2	collagen, type XI, alpha 2	0.026
E2F6	E2F transcription factor 6	0.025	Human
SIRT1	sirtuin 1	0.024
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.024	Human
ITGB1BP3	integrin beta 1 binding protein 3	0.024
STMN2	stathmin-like 2	0.023
GPI	glucose-6-phosphate isomerase	0.023
CAV1	caveolin 1, caveolae protein, 22kDa	0.023
BAK1	BCL2-antagonist/killer 1	0.023
TPI1	triosephosphate isomerase 1	0.023
MYBL2	v-myb myeloblastosis viral oncogene homolog (avian)-like 2	0.022
CDK1	cyclin-dependent kinase 1	0.022
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.022
ADAMTSL4	ADAMTS-like 4	0.021
PDGFC	platelet derived growth factor C	0.021
ALK	anaplastic lymphoma receptor tyrosine kinase	0.021
PKM2	pyruvate kinase, muscle	0.021
PLCG1	phospholipase C, gamma 1	0.020
E2F2	E2F transcription factor 2	0.020	Human
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.020
KITLG	KIT ligand	0.020
BCOR	BCL6 corepressor	0.020
BCL6	B-cell CLL/lymphoma 6	0.020
NBN	nibrin	0.019
CUX1	cut-like homeobox 1	0.019
KLF10	Kruppel-like factor 10	0.019
HBP1	HMG-box transcription factor 1	0.019
RARA	retinoic acid receptor, alpha	0.019
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.019	Human
CABLES1	Cdk5 and Abl enzyme substrate 1	0.019
VEGFC	vascular endothelial growth factor C	0.018	Human
SELENBP1	selenium binding protein 1	0.018
KCTD17	potassium channel tetramerisation domain containing 17	0.018
BAZ1A	bromodomain adjacent to zinc finger domain, 1A	0.018
TIMP3	TIMP metallopeptidase inhibitor 3	0.018
COPS6	COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)	0.018
NCOA6	nuclear receptor coactivator 6	0.018
ZNF267	zinc finger protein 267	0.018
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.017	Rat
PCGF5	polycomb group ring finger 5	0.017	Human
UBQLN4	ubiquilin 4	0.017
ICAM1	intercellular adhesion molecule 1	0.017
CDH5	cadherin 5, type 2 (vascular endothelium)	0.017
EFEMP2	EGF containing fibulin-like extracellular matrix protein 2	0.017
BHLHE40	basic helix-loop-helix family, member e40	0.017
GRB7	growth factor receptor-bound protein 7	0.017
DNAJB2	DnaJ (Hsp40) homolog, subfamily B, member 2	0.017
BIRC2	baculoviral IAP repeat containing 2	0.017
PML	promyelocytic leukemia	0.017
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.016
LDHA	lactate dehydrogenase A	0.016
H2AFX	H2A histone family, member X	0.016
SMAD4	SMAD family member 4	0.016
PURA	purine-rich element binding protein A	0.016
IER3	immediate early response 3	0.016
DCN	decorin	0.016
SFRP1	secreted frizzled-related protein 1	0.016
KAT2B	K(lysine) acetyltransferase 2B	0.016
AHR	aryl hydrocarbon receptor	0.016
ATF3	activating transcription factor 3	0.016
WWOX	WW domain containing oxidoreductase	0.016
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.016
RIPK2	receptor-interacting serine-threonine kinase 2	0.016
ATXN1	ataxin 1	0.015
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.015
SATB2	SATB homeobox 2	0.015
CDT1	chromatin licensing and DNA replication factor 1	0.015
BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	0.015
NHEJ1	nonhomologous end-joining factor 1	0.015
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.015
RNR2	l-rRNA	0.015
CHEK2	CHK2 checkpoint homolog (S. pombe)	0.015
FKBP8	FK506 binding protein 8, 38kDa	0.015
CBX4	chromobox homolog 4	0.015
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.014
BLZF1	basic leucine zipper nuclear factor 1	0.014
SMAD3	SMAD family member 3	0.014
PSAP	prosaposin	0.014
MKRN1	makorin ring finger protein 1	0.014
PSEN2	presenilin 2 (Alzheimer disease 4)	0.014
FOSL1	FOS-like antigen 1	0.014
YAF2	YY1 associated factor 2	0.014
COL6A1	collagen, type VI, alpha 1	0.014
SALL2	sal-like 2 (Drosophila)	0.014
PECAM1	platelet/endothelial cell adhesion molecule	0.013
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.013
ARRDC3	arrestin domain containing 3	0.013
UBR1	ubiquitin protein ligase E3 component n-recognin 1	0.013
YAP1	Yes-associated protein 1	0.013
PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	0.013
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.013
CHEK1	CHK1 checkpoint homolog (S. pombe)	0.013
PSEN1	presenilin 1	0.013
PGAM1	phosphoglycerate mutase 1 (brain)	0.013
PLSCR1	phospholipid scramblase 1	0.013
STC1	stanniocalcin 1	0.013
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.013
LAP3	leucine aminopeptidase 3	0.013
MDFI	MyoD family inhibitor	0.013
LRP6	low density lipoprotein receptor-related protein 6	0.013
TP53BP2	tumor protein p53 binding protein, 2	0.013
PRMT6	protein arginine methyltransferase 6	0.013
CD33	CD33 molecule	0.012
CTBP2	C-terminal binding protein 2	0.012
DDIT3	DNA-damage-inducible transcript 3	0.012
PMF1	polyamine-modulated factor 1	0.012
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.012
SKP1	S-phase kinase-associated protein 1	0.012
FGFR1	fibroblast growth factor receptor 1	0.012
CRYAB	crystallin, alpha B	0.012
PKMYT1	protein kinase, membrane associated tyrosine/threonine 1	0.012
PTN	pleiotrophin	0.012
FGF18	fibroblast growth factor 18	0.012
WNT2	wingless-type MMTV integration site family member 2	0.012
NGF	nerve growth factor (beta polypeptide)	0.012
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.012
THBS1	thrombospondin 1	0.012
PACSIN1	protein kinase C and casein kinase substrate in neurons 1	0.012
CKS2	CDC28 protein kinase regulatory subunit 2	0.012
CEBPD	CCAAT/enhancer binding protein (C/EBP), delta	0.012
NCOA1	nuclear receptor coactivator 1	0.012
WNT1	wingless-type MMTV integration site family, member 1	0.011
EPAS1	endothelial PAS domain protein 1	0.011
PHC2	polyhomeotic homolog 2 (Drosophila)	0.011
ADM	adrenomedullin	0.011
S1PR5	sphingosine-1-phosphate receptor 5	0.011
HAP1	huntingtin-associated protein 1	0.011
IFIH1	interferon induced with helicase C domain 1	0.011
TCF4	transcription factor 4	0.011
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.011
FZD8	frizzled homolog 8 (Drosophila)	0.011
AXIN1	axin 1	0.011
INSR	insulin receptor	0.011
DDIT4	DNA-damage-inducible transcript 4	0.011
KRT6C	keratin 6C	0.011
ENG	endoglin	0.011
OAZ1	ornithine decarboxylase antizyme 1	0.011
TEK	TEK tyrosine kinase, endothelial	0.011
WIF1	WNT inhibitory factor 1	0.011
CDK5	cyclin-dependent kinase 5	0.011
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.011
ZBTB16	zinc finger and BTB domain containing 16	0.011
PNRC1	proline-rich nuclear receptor coactivator 1	0.011
CD34	CD34 molecule	0.011
ATP6V1F	ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F	0.011
USP15	ubiquitin specific peptidase 15	0.011
BIK	BCL2-interacting killer (apoptosis-inducing)	0.011
RAD18	RAD18 homolog (S. cerevisiae)	0.011
MEP1A	meprin A, alpha (PABA peptide hydrolase)	0.011
BCAR1	breast cancer anti-estrogen resistance 1	0.011
DYRK1B	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.011
TRIM5	tripartite motif containing 5	0.011
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.010
SAT1	spermidine/spermine N1-acetyltransferase 1	0.010
PTPRB	protein tyrosine phosphatase, receptor type, B	0.010
PDE9A	phosphodiesterase 9A	0.010
HDAC2	histone deacetylase 2	0.010
PCGF6	polycomb group ring finger 6	0.010	Human
TIMP1	TIMP metallopeptidase inhibitor 1	0.010
SAMD9L	sterile alpha motif domain containing 9-like	0.010
NRIP1	nuclear receptor interacting protein 1	0.010
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.010
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.010
COL2A1	collagen, type II, alpha 1	0.010
SORBS3	sorbin and SH3 domain containing 3	0.010
MAPK8	mitogen-activated protein kinase 8	0.010
ZBTB45	zinc finger and BTB domain containing 45	0.010
TGFB2	transforming growth factor, beta 2	0.010