IMP

Process View

Mus musculus

4 genes annotated in mouse

Multi-species View

toll like receptor 7 signaling pathway

GO:0034154

Any series of molecular signals generated as a consequence of binding to toll-like receptor 7.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "toll like receptor 7 signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "toll like receptor 7 signaling pathway" (in gray)

Name	Description	Probability
Irf7	interferon regulatory factor 7	0.854
Dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58	0.769
Myd88	myeloid differentiation primary response gene 88	0.591
Cmpk2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial	0.351
BC013712	cDNA sequence BC013712	0.350
Fcgr4	Fc receptor, IgG, low affinity IV	0.344
Pyhin1	pyrin and HIN domain family, member 1	0.328
Nlrp3	NLR family, pyrin domain containing 3	0.306
Ly86	lymphocyte antigen 86	0.304
Zbp1	Z-DNA binding protein 1	0.278
Cd180	CD180 antigen	0.266
Trim30a	tripartite motif-containing 30A	0.230
Tlr4	toll-like receptor 4	0.197
Sfpi1	SFFV proviral integration 1	0.188
Il10ra	interleukin 10 receptor, alpha	0.187
Trim30d	tripartite motif-containing 30D	0.183
Ifit1	interferon-induced protein with tetratricopeptide repeats 1	0.177
Itgal	integrin alpha L	0.170
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.160
Fcgr1	Fc receptor, IgG, high affinity I	0.158
Rtp4	receptor transporter protein 4	0.157
Oas2	2'-5' oligoadenylate synthetase 2	0.138
Ddx60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.135
Lair1	leukocyte-associated Ig-like receptor 1	0.132
Ncf1	neutrophil cytosolic factor 1	0.125
Sp100	nuclear antigen Sp100	0.125
Cd300ld	CD300 molecule-like family member d	0.120
Epsti1	epithelial stromal interaction 1 (breast)	0.110
Csf1r	colony stimulating factor 1 receptor	0.109
Tyrobp	TYRO protein tyrosine kinase binding protein	0.105
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.104
Cybb	cytochrome b-245, beta polypeptide	0.100
Cd86	CD86 antigen	0.099
Pilra	paired immunoglobin-like type 2 receptor alpha	0.099
Ifih1	interferon induced with helicase C domain 1	0.097
Tmem106a	transmembrane protein 106A	0.095
Usp18	ubiquitin specific peptidase 18	0.094
Ifi27l2a	interferon, alpha-inducible protein 27 like 2A	0.093
Tlr2	toll-like receptor 2	0.090
Isg15	ISG15 ubiquitin-like modifier	0.086
Gm12185	predicted gene 12185	0.086
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.084
Msr1	macrophage scavenger receptor 1	0.083
Oasl2	2'-5' oligoadenylate synthetase-like 2	0.082
Tbxas1	thromboxane A synthase 1, platelet	0.081
P2ry13	purinergic receptor P2Y, G-protein coupled 13	0.081
Ctss	cathepsin S	0.080
Oasl1	2'-5' oligoadenylate synthetase-like 1	0.078
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.077
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.076
Lcp2	lymphocyte cytosolic protein 2	0.075
Siglece	sialic acid binding Ig-like lectin E	0.073
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.072
Cxcl9	chemokine (C-X-C motif) ligand 9	0.070
Slc15a3	solute carrier family 15, member 3	0.069
Slamf7	SLAM family member 7	0.069
Ifitm6	interferon induced transmembrane protein 6	0.068
Ifi203	interferon activated gene 203	0.068
Slamf8	SLAM family member 8	0.064
Clec7a	C-type lectin domain family 7, member a	0.063
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.062
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.062
Btk	Bruton agammaglobulinemia tyrosine kinase	0.061
Nfam1	Nfat activating molecule with ITAM motif 1	0.059
Aif1	allograft inflammatory factor 1	0.058
Il18rap	interleukin 18 receptor accessory protein	0.057
Igsf6	immunoglobulin superfamily, member 6	0.054
Mefv	Mediterranean fever	0.053
Sdc3	syndecan 3	0.049
Irf5	interferon regulatory factor 5	0.049
Ccl4	chemokine (C-C motif) ligand 4	0.048
Mpeg1	macrophage expressed gene 1	0.048
Cd33	CD33 antigen	0.048
Tifab	TRAF-interacting protein with forkhead-associated domain, family member B	0.047
Slamf6	SLAM family member 6	0.047
Gm885	predicted gene 885	0.047
Clec4n	C-type lectin domain family 4, member n	0.045
Slfn2	schlafen 2	0.045
Slamf1	signaling lymphocytic activation molecule family member 1	0.044
Ifi44	interferon-induced protein 44	0.044
Tnf	tumor necrosis factor	0.044
Pld4	phospholipase D family, member 4	0.043
Pilrb1	paired immunoglobin-like type 2 receptor beta 1	0.043
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.042
Ube2l6	ubiquitin-conjugating enzyme E2L 6	0.041
Cd84	CD84 antigen	0.041
Gpr84	G protein-coupled receptor 84	0.041
Arhgap30	Rho GTPase activating protein 30	0.040
Inpp5d	inositol polyphosphate-5-phosphatase D	0.040
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.040
Snx20	sorting nexin 20	0.040
C1qc	complement component 1, q subcomponent, C chain	0.039
Mx1	myxovirus (influenza virus) resistance 1	0.039
Casp1	caspase 1	0.039
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.039
Mx2	myxovirus (influenza virus) resistance 2	0.038
Gbp7	guanylate binding protein 7	0.038
Tlr8	toll-like receptor 8	0.038
Fyb	FYN binding protein	0.038
Ebi3	Epstein-Barr virus induced gene 3	0.037
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.037
Ly9	lymphocyte antigen 9	0.037
Gm6377	predicted gene 6377	0.036
Hck	hemopoietic cell kinase	0.036
Cxcl10	chemokine (C-X-C motif) ligand 10	0.036
5430427O19Rik	RIKEN cDNA 5430427O19 gene	0.036
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.036
Myo1g	myosin IG	0.036
Sla	src-like adaptor	0.035
Oas3	2'-5' oligoadenylate synthetase 3	0.035
Parp14	poly (ADP-ribose) polymerase family, member 14	0.035
Lyz2	lysozyme 2	0.035
Cd300a	CD300A antigen	0.033
Il1b	interleukin 1 beta	0.033
C3ar1	complement component 3a receptor 1	0.032
Tor3a	torsin family 3, member A	0.032
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.032
Irf9	interferon regulatory factor 9	0.032
Dok3	docking protein 3	0.032
Ccr2	chemokine (C-C motif) receptor 2	0.031
Clec5a	C-type lectin domain family 5, member a	0.031
Clec4a2	C-type lectin domain family 4, member a2	0.030
Irak4	interleukin-1 receptor-associated kinase 4	0.030
Tirap	toll-interleukin 1 receptor (TIR) domain-containing adaptor protein	0.030
Ms4a6b	membrane-spanning 4-domains, subfamily A, member 6B	0.030
Emr4	EGF-like module containing, mucin-like, hormone receptor-like sequence 4	0.029
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.029
Tgfb1	transforming growth factor, beta 1	0.029
Unc93b1	unc-93 homolog B1 (C. elegans)	0.029
Parvg	parvin, gamma	0.029
Oas1b	2'-5' oligoadenylate synthetase 1B	0.029
Abcg3	ATP-binding cassette, sub-family G (WHITE), member 3	0.029
Nckap1l	NCK associated protein 1 like	0.028
Trim21	tripartite motif-containing 21	0.028
Irgm1	immunity-related GTPase family M member 1	0.028
Csprs	component of Sp100-rs	0.028
Irf8	interferon regulatory factor 8	0.027
Gbp3	guanylate binding protein 3	0.027
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.027
Sash3	SAM and SH3 domain containing 3	0.026
Ddx58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.026
Stap1	signal transducing adaptor family member 1	0.026
D14Ertd668e	DNA segment, Chr 14, ERATO Doi 668, expressed	0.025
Serpinb9	serine (or cysteine) peptidase inhibitor, clade B, member 9	0.025
Mavs	mitochondrial antiviral signaling protein	0.024
Cd37	CD37 antigen	0.024
Ccl3	chemokine (C-C motif) ligand 3	0.024
Cd72	CD72 antigen	0.024
Parp12	poly (ADP-ribose) polymerase family, member 12	0.024
Trem3	triggering receptor expressed on myeloid cells 3	0.024
Runx3	runt related transcription factor 3	0.024
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.023
Lgals3bp	lectin, galactoside-binding, soluble, 3 binding protein	0.023
Ccl5	chemokine (C-C motif) ligand 5	0.023
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	0.023
Oas1a	2'-5' oligoadenylate synthetase 1A	0.022
Plekho2	pleckstrin homology domain containing, family O member 2	0.022
Naip2	NLR family, apoptosis inhibitory protein 2	0.022
Slfn8	schlafen 8	0.022
Tifa	TRAF-interacting protein with forkhead-associated domain	0.022
Rgs1	regulator of G-protein signaling 1	0.022
Rhoh	ras homolog gene family, member H	0.022
Samhd1	SAM domain and HD domain, 1	0.022
Clec4b1	C-type lectin domain family 4, member b1	0.021
Neurl3	neuralized homolog 3 homolog (Drosophila)	0.021
Hk3	hexokinase 3	0.021
Batf	basic leucine zipper transcription factor, ATF-like	0.021
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.021
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.020
Apbb1ip	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	0.020
Zc3h12d	zinc finger CCCH type containing 12D	0.020
Mxd1	MAX dimerization protein 1	0.020
Slamf9	SLAM family member 9	0.020
Mnda	myeloid cell nuclear differentiation antigen	0.019
Gm11428	predicted gene 11428	0.019
Hpgds	hematopoietic prostaglandin D synthase	0.019
Il4ra	interleukin 4 receptor, alpha	0.019
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.018
Plek	pleckstrin	0.018
Cd300lf	CD300 antigen like family member F	0.018
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.018
AF251705	cDNA sequence AF251705	0.018
Aim2	absent in melanoma 2	0.018
Selplg	selectin, platelet (p-selectin) ligand	0.018
Batf2	basic leucine zipper transcription factor, ATF-like 2	0.017
March1	membrane-associated ring finger (C3HC4) 1	0.017
Tnfrsf14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.017
Sell	selectin, lymphocyte	0.017
Il1rn	interleukin 1 receptor antagonist	0.017
Lpxn	leupaxin	0.017
Csf1	colony stimulating factor 1 (macrophage)	0.017
Gimap3	GTPase, IMAP family member 3	0.017
AB124611	cDNA sequence AB124611	0.017
Evi2b	ecotropic viral integration site 2b	0.017
Herc6	hect domain and RLD 6	0.016
Gbp2	guanylate binding protein 2	0.016
Rnase6	ribonuclease, RNase A family, 6	0.016
Clec4a3	C-type lectin domain family 4, member a3	0.016
Dock2	dedicator of cyto-kinesis 2	0.016
Gpr65	G-protein coupled receptor 65	0.016
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.016
Tlr6	toll-like receptor 6	0.016
Stat1	signal transducer and activator of transcription 1	0.016
C1qb	complement component 1, q subcomponent, beta polypeptide	0.015
Tlr1	toll-like receptor 1	0.015
Sp110	Sp110 nuclear body protein	0.015
Ccr5	chemokine (C-C motif) receptor 5	0.015
Iigp1	interferon inducible GTPase 1	0.015
Il1r1	interleukin 1 receptor, type I	0.015
Grb2	growth factor receptor bound protein 2	0.015
Klra17	killer cell lectin-like receptor, subfamily A, member 17	0.015
Pdcd1lg2	programmed cell death 1 ligand 2	0.015
Cyp4f18	cytochrome P450, family 4, subfamily f, polypeptide 18	0.015
P2ry12	purinergic receptor P2Y, G-protein coupled 12	0.014
Fcrl1	Fc receptor-like 1	0.014
Clec4e	C-type lectin domain family 4, member e	0.014
Gzma	granzyme A	0.014
Isg20	interferon-stimulated protein	0.014
Clec4d	C-type lectin domain family 4, member d	0.014
Cxcl16	chemokine (C-X-C motif) ligand 16	0.014
Ms4a7	membrane-spanning 4-domains, subfamily A, member 7	0.014
Arhgap25	Rho GTPase activating protein 25	0.014
B430306N03Rik	RIKEN cDNA B430306N03 gene	0.014
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.014
Was	Wiskott-Aldrich syndrome homolog (human)	0.013
Sept1	septin 1	0.013
Adam8	a disintegrin and metallopeptidase domain 8	0.013
Adap2	ArfGAP with dual PH domains 2	0.013
Il10	interleukin 10	0.013
Cd274	CD274 antigen	0.013
Mlkl	mixed lineage kinase domain-like	0.013
Fcrla	Fc receptor-like A	0.013
Cd69	CD69 antigen	0.013
Pou2f2	POU domain, class 2, transcription factor 2	0.012
Cd300lb	CD300 antigen like family member B	0.012
Samd9l	sterile alpha motif domain containing 9-like	0.012
Ifit2	interferon-induced protein with tetratricopeptide repeats 2	0.012
Ticam1	toll-like receptor adaptor molecule 1	0.012
Niacr1	niacin receptor 1	0.012
Itga4	integrin alpha 4	0.012
Cd48	CD48 antigen	0.012
Il2	interleukin 2	0.012
Cd22	CD22 antigen	0.012
Hcls1	hematopoietic cell specific Lyn substrate 1	0.012
Ear2	eosinophil-associated, ribonuclease A family, member 2	0.012
5430435G22Rik	RIKEN cDNA 5430435G22 gene	0.011
Gpr35	G protein-coupled receptor 35	0.011
Slpi	secretory leukocyte peptidase inhibitor	0.011
Cysltr1	cysteinyl leukotriene receptor 1	0.011
Itgb2	integrin beta 2	0.011
A630033H20Rik	RIKEN cDNA A630033H20 gene	0.011
Vav1	vav 1 oncogene	0.011
Slc37a2	solute carrier family 37 (glycerol-3-phosphate transporter), member 2	0.011
Irgm2	immunity-related GTPase family M member 2	0.011
Trem1	triggering receptor expressed on myeloid cells 1	0.011
Xaf1	XIAP associated factor 1	0.011
Gbgt1	globoside alpha-1,3-N-acetylgalactosaminyltransferase 1	0.010
Fas	Fas (TNF receptor superfamily member 6)	0.010
Dock8	dedicator of cytokinesis 8	0.010
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.010
Naip5	NLR family, apoptosis inhibitory protein 5	0.010
Irg1	immunoresponsive gene 1	0.010
Cxcr2	chemokine (C-X-C motif) receptor 2	0.010
LOC677008	natural killer cell receptor 2B4-like	0.010