IMP

Process View

Mus musculus

1 genes annotated in mouse

Multi-species View

regulation of eosinophil degranulation

GO:0043309

Any process that modulates the frequency, rate, or extent of eosinophil degranulation.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of eosinophil degranulation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of eosinophil degranulation" (in gray)

Name	Description	Probability	Func Analog Organism
Ccr2	chemokine (C-C motif) receptor 2	0.934
Ccr6	chemokine (C-C motif) receptor 6	0.842	Mouse
Il2rb	interleukin 2 receptor, beta chain	0.803
Cd3e	CD3 antigen, epsilon polypeptide	0.760
Ccr5	chemokine (C-C motif) receptor 5	0.751	Mouse
Xcr1	chemokine (C motif) receptor 1	0.626	Mouse
Ifng	interferon gamma	0.606
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.599
Fcrla	Fc receptor-like A	0.544
Cd19	CD19 antigen	0.490
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.462
Blk	B lymphoid kinase	0.450
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.416
Cd7	CD7 antigen	0.394
Icos	inducible T-cell co-stimulator	0.389
Mmp9	matrix metallopeptidase 9	0.386
Cd180	CD180 antigen	0.360
Sit1	suppression inducing transmembrane adaptor 1	0.353
Fcer2a	Fc receptor, IgE, low affinity II, alpha polypeptide	0.348
Prdm1	PR domain containing 1, with ZNF domain	0.333
Ikzf1	IKAROS family zinc finger 1	0.327
Sh2d2a	SH2 domain protein 2A	0.321
Itk	IL2-inducible T-cell kinase	0.320
Cd22	CD22 antigen	0.314
Ccl2	chemokine (C-C motif) ligand 2	0.301
Lta	lymphotoxin A	0.270
Ms4a1	membrane-spanning 4-domains, subfamily A, member 1	0.268
H2-Ob	histocompatibility 2, O region beta locus	0.257
Ciita	class II transactivator	0.249
Fasl	Fas ligand (TNF superfamily, member 6)	0.248
Sell	selectin, lymphocyte	0.239
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.231
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.229
Cxcl13	chemokine (C-X-C motif) ligand 13	0.224
Ccl3	chemokine (C-C motif) ligand 3	0.218
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.217
Ncr1	natural cytotoxicity triggering receptor 1	0.212
Tnf	tumor necrosis factor	0.212
S1pr4	sphingosine-1-phosphate receptor 4	0.188
Il18rap	interleukin 18 receptor accessory protein	0.180
Pla2g2d	phospholipase A2, group IID	0.171
Gzmk	granzyme K	0.168
Cd96	CD96 antigen	0.166
Il27ra	interleukin 27 receptor, alpha	0.165
Klra9	killer cell lectin-like receptor subfamily A, member 9	0.160
Fgd3	FYVE, RhoGEF and PH domain containing 3	0.156
Gcet2	germinal center expressed transcript 2	0.147
Selp	selectin, platelet	0.147
Xcl1	chemokine (C motif) ligand 1	0.138
Cd4	CD4 antigen	0.129
Il18r1	interleukin 18 receptor 1	0.128
Pyhin1	pyrin and HIN domain family, member 1	0.125
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.122
Itgax	integrin alpha X	0.119
Cd6	CD6 antigen	0.115
Cxcr5	chemokine (C-X-C motif) receptor 5	0.113	Mouse
Cd5	CD5 antigen	0.110
Slamf1	signaling lymphocytic activation molecule family member 1	0.110
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.109
Cd28	CD28 antigen	0.108
Cd2	CD2 antigen	0.105
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.105
Gzmb	granzyme B	0.104
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.101
Foxp3	forkhead box P3	0.101
Slamf6	SLAM family member 6	0.099
Ccr7	chemokine (C-C motif) receptor 7	0.097	Mouse
Spn	sialophorin	0.097
Gpr132	G protein-coupled receptor 132	0.096
Il4	interleukin 4	0.093
Itgal	integrin alpha L	0.090
Cxcr3	chemokine (C-X-C motif) receptor 3	0.088	Mouse
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.085
Cd44	CD44 antigen	0.081
Igk	immunoglobulin kappa chain complex	0.079
Il10	interleukin 10	0.079
Gimap7	GTPase, IMAP family member 7	0.078
Pou2af1	POU domain, class 2, associating factor 1	0.073
Ctsw	cathepsin W	0.072
Ltb	lymphotoxin B	0.071
Rhoh	ras homolog gene family, member H	0.063
Ccr3	chemokine (C-C motif) receptor 3	0.061	Mouse
Tnfrsf17	tumor necrosis factor receptor superfamily, member 17	0.061
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.060
Il12rb2	interleukin 12 receptor, beta 2	0.060
Cd8b1	CD8 antigen, beta chain 1	0.059
H2-Oa	histocompatibility 2, O region alpha locus	0.059
Cr2	complement receptor 2	0.058
Cd8a	CD8 antigen, alpha chain	0.057
Il7r	interleukin 7 receptor	0.057
H2-Eb2	histocompatibility 2, class II antigen E beta2	0.057
Lyz2	lysozyme 2	0.056
Elk4	ELK4, member of ETS oncogene family	0.055
Art2a-ps	ADP-ribosyltransferase 2a, pseudogene	0.054
Olfr140	olfactory receptor 140	0.053
Tnfsf8	tumor necrosis factor (ligand) superfamily, member 8	0.050
Bex6	brain expressed gene 6	0.049
Cxcr2	chemokine (C-X-C motif) receptor 2	0.049	Mouse
Pcdh12	protocadherin 12	0.048
Grap2	GRB2-related adaptor protein 2	0.048
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.047
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.045
Ccr1	chemokine (C-C motif) receptor 1	0.044	Mouse
Ccr1l1	chemokine (C-C motif) receptor 1-like 1	0.044	Mouse
Igj	immunoglobulin joining chain	0.044
Cd247	CD247 antigen	0.043
Btk	Bruton agammaglobulinemia tyrosine kinase	0.042
Fcrl1	Fc receptor-like 1	0.042
Tlr2	toll-like receptor 2	0.041
Flt3	FMS-like tyrosine kinase 3	0.041
Clec2i	C-type lectin domain family 2, member i	0.041
Pdcd1	programmed cell death 1	0.041
Mmp8	matrix metallopeptidase 8	0.041
Gzma	granzyme A	0.040
Vpreb3	pre-B lymphocyte gene 3	0.040
Elf4	E74-like factor 4 (ets domain transcription factor)	0.039
Uts2r	urotensin 2 receptor	0.039
Dnase1l3	deoxyribonuclease 1-like 3	0.039
Tlr4	toll-like receptor 4	0.038
Tspo2	translocator protein 2	0.037
Itgae	integrin alpha E, epithelial-associated	0.037
Abcg3	ATP-binding cassette, sub-family G (WHITE), member 3	0.036
Irf4	interferon regulatory factor 4	0.036
Prg3	proteoglycan 3	0.036
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.036
Tbx21	T-box 21	0.036
Txk	TXK tyrosine kinase	0.035
Npy1r	neuropeptide Y receptor Y1	0.035
Gimap3	GTPase, IMAP family member 3	0.035
Ear2	eosinophil-associated, ribonuclease A family, member 2	0.035
Itga4	integrin alpha 4	0.035
Ptprc	protein tyrosine phosphatase, receptor type, C	0.034
Il1b	interleukin 1 beta	0.033
Art2b	ADP-ribosyltransferase 2b	0.033
Pdcd1lg2	programmed cell death 1 ligand 2	0.033
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.033
Cx3cr1	chemokine (C-X3-C) receptor 1	0.032	Mouse
C3ar1	complement component 3a receptor 1	0.031
Cd3g	CD3 antigen, gamma polypeptide	0.031
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.031
Cnr2	cannabinoid receptor 2 (macrophage)	0.030
Prf1	perforin 1 (pore forming protein)	0.030
Il9r	interleukin 9 receptor	0.030
Tff1	trefoil factor 1	0.030
Cd3d	CD3 antigen, delta polypeptide	0.029
Il1rl1	interleukin 1 receptor-like 1	0.029
Hr	hairless	0.029
Gp9	glycoprotein 9 (platelet)	0.028
Asprv1	aspartic peptidase, retroviral-like 1	0.028
Ly9	lymphocyte antigen 9	0.028
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.028
Cd40	CD40 antigen	0.028
Ccl4	chemokine (C-C motif) ligand 4	0.028
Cnga1	cyclic nucleotide gated channel alpha 1	0.028
Sele	selectin, endothelial cell	0.027
Kcna3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.027
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.027
Il2ra	interleukin 2 receptor, alpha chain	0.026
Gpr33	G protein-coupled receptor 33	0.026
Ly6d	lymphocyte antigen 6 complex, locus D	0.026
Ppef2	protein phosphatase, EF hand calcium-binding domain 2	0.026
Ccl22	chemokine (C-C motif) ligand 22	0.025
Wisp2	WNT1 inducible signaling pathway protein 2	0.025
Mefv	Mediterranean fever	0.024
Tlr7	toll-like receptor 7	0.024
Rgs14	regulator of G-protein signaling 14	0.023
Camk4	calcium/calmodulin-dependent protein kinase IV	0.023
Cd160	CD160 antigen	0.022
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.022
Emr4	EGF-like module containing, mucin-like, hormone receptor-like sequence 4	0.022
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.022
Efna1	ephrin A1	0.021
C5ar1	complement component 5a receptor 1	0.021
Cxcr6	chemokine (C-X-C motif) receptor 6	0.021	Mouse
Cd79b	CD79B antigen	0.021
Dock1	dedicator of cytokinesis 1	0.021
Sh2d1a	SH2 domain protein 1A	0.021
Adamdec1	ADAM-like, decysin 1	0.020
Runx1	runt related transcription factor 1	0.020
Cd209a	CD209a antigen	0.020
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.020
Zan	zonadhesin	0.020
Il12a	interleukin 12a	0.020
Tcstv3	2-cell-stage, variable group, member 3	0.020
Lcn4	lipocalin 4	0.019
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.019
Olfr93	olfactory receptor 93	0.019
Psp	parotid secretory protein	0.019
Oosp1	oocyte secreted protein 1	0.019
Spp1	secreted phosphoprotein 1	0.019
Pabpc2	poly(A) binding protein, cytoplasmic 2	0.019
Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	0.019
Star	steroidogenic acute regulatory protein	0.019
Prl4a1	prolactin family 4, subfamily a, member 1	0.018
Lat	linker for activation of T cells	0.018
Dusp2	dual specificity phosphatase 2	0.018
Il21r	interleukin 21 receptor	0.018
C80012	expressed sequence C80012	0.018
H2-M9	histocompatibility 2, M region locus 9	0.018
Gimap1	GTPase, IMAP family member 1	0.018
Il7	interleukin 7	0.018
Itga2	integrin alpha 2	0.017
Bdkrb1	bradykinin receptor, beta 1	0.017
Fosb	FBJ osteosarcoma oncogene B	0.017
Il10ra	interleukin 10 receptor, alpha	0.017
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.017
Ccr9	chemokine (C-C motif) receptor 9	0.017	Mouse
Tnfrsf13c	tumor necrosis factor receptor superfamily, member 13c	0.017
Slamf7	SLAM family member 7	0.017
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.017
Cysltr2	cysteinyl leukotriene receptor 2	0.017
Cd27	CD27 antigen	0.016
Abp1	amiloride binding protein 1 (amine oxidase, copper-containing)	0.016
Mcpt8	mast cell protease 8	0.016
Kmo	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.016
Stat4	signal transducer and activator of transcription 4	0.016
Klrb1c	killer cell lectin-like receptor subfamily B member 1C	0.016
Ccr4	chemokine (C-C motif) receptor 4	0.016	Mouse
Gdf9	growth differentiation factor 9	0.016
Fas	Fas (TNF receptor superfamily member 6)	0.016
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.016
Gpr18	G protein-coupled receptor 18	0.016
Lepr	leptin receptor	0.016
Fut4	fucosyltransferase 4	0.016
Opn1sw	opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)	0.015
LOC100502924	hypothetical protein LOC100502924	0.015
Tssk1	testis-specific serine kinase 1	0.015
Rasgrp1	RAS guanyl releasing protein 1	0.015
Fgf7	fibroblast growth factor 7	0.015
Cd300ld	CD300 molecule-like family member d	0.015
Itgam	integrin alpha M	0.015
Serpinb7	serine (or cysteine) peptidase inhibitor, clade B, member 7	0.015
Hrh1	histamine receptor H1	0.015
Cd86	CD86 antigen	0.015
Havcr2	hepatitis A virus cellular receptor 2	0.015
Ubd	ubiquitin D	0.015
Hivep3	human immunodeficiency virus type I enhancer binding protein 3	0.014
Chst3	carbohydrate (chondroitin 6/keratan) sulfotransferase 3	0.014
Rhag	Rhesus blood group-associated A glycoprotein	0.014
Cdh1	cadherin 1	0.014
Mpo	myeloperoxidase	0.014
Ighg	Immunoglobulin heavy chain (gamma polypeptide)	0.014
Krt6b	keratin 6B	0.014
LOC100503923	hypothetical protein LOC100503923	0.014
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.014
Mc5r	melanocortin 5 receptor	0.014
Stap1	signal transducing adaptor family member 1	0.014
Cysltr1	cysteinyl leukotriene receptor 1	0.014
Klra17	killer cell lectin-like receptor, subfamily A, member 17	0.014
Ptgir	prostaglandin I receptor (IP)	0.014
Trem3	triggering receptor expressed on myeloid cells 3	0.014
Oxt	oxytocin	0.014
Il16	interleukin 16	0.014
Cd244	CD244 natural killer cell receptor 2B4	0.014
Fpr3	formyl peptide receptor 3	0.014
Ifngr1	interferon gamma receptor 1	0.014
Rab37	RAB37, member of RAS oncogene family	0.014
Prg2	proteoglycan 2, bone marrow	0.014
Gimap4	GTPase, IMAP family member 4	0.013
Cma1	chymase 1, mast cell	0.013
Faim3	Fas apoptotic inhibitory molecule 3	0.013
Gpr174	G protein-coupled receptor 174	0.013
Mecom	MDS1 and EVI1 complex locus	0.013
Mc2r	melanocortin 2 receptor	0.013
Kynu	kynureninase (L-kynurenine hydrolase)	0.013
Rel	reticuloendotheliosis oncogene	0.013
Ptger2	prostaglandin E receptor 2 (subtype EP2)	0.013
Srms	src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites	0.013
F2rl1	coagulation factor II (thrombin) receptor-like 1	0.013	Human
Ikzf2	IKAROS family zinc finger 2	0.013
Itgb7	integrin beta 7	0.013
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2	0.013
Il15ra	interleukin 15 receptor, alpha chain	0.013
Inpp5d	inositol polyphosphate-5-phosphatase D	0.013
Htr2b	5-hydroxytryptamine (serotonin) receptor 2B	0.013
Slc34a1	solute carrier family 34 (sodium phosphate), member 1	0.012
Wnt10a	wingless related MMTV integration site 10a	0.012
Reg3g	regenerating islet-derived 3 gamma	0.012
Spo11	sporulation protein, meiosis-specific, SPO11 homolog (S. cerevisiae)	0.012
Crtam	cytotoxic and regulatory T cell molecule	0.012
St6galnac1	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1	0.012
Klrb1f	killer cell lectin-like receptor subfamily B member 1F	0.012
Cybb	cytochrome b-245, beta polypeptide	0.012
Opn4	opsin 4 (melanopsin)	0.012
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.012
Endou	endonuclease, polyU-specific	0.012
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.012
Cox8c	cytochrome c oxidase, subunit VIIIc	0.012
Car1	carbonic anhydrase 1	0.012
Ms4a4b	membrane-spanning 4-domains, subfamily A, member 4B	0.012
Cd207	CD207 antigen	0.012
Nkg7	natural killer cell group 7 sequence	0.012
Il1a	interleukin 1 alpha	0.012
Cst7	cystatin F (leukocystatin)	0.012
Efnb2	ephrin B2	0.012
Tbx6	T-box 6	0.012
Cytip	cytohesin 1 interacting protein	0.012
Gcnt1	glucosaminyl (N-acetyl) transferase 1, core 2	0.011
Slamf8	SLAM family member 8	0.011
St6galnac3	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3	0.011
Krtap13	keratin associated protein 13	0.011
Gna15	guanine nucleotide binding protein, alpha 15	0.011
Il15	interleukin 15	0.011
Tcra	T-cell receptor alpha chain	0.011
Tlr8	toll-like receptor 8	0.011
Gypa	glycophorin A	0.011
Id2	inhibitor of DNA binding 2	0.011
Cd209b	CD209b antigen	0.011
Gbp1	guanylate binding protein 1	0.011
Ikzf3	IKAROS family zinc finger 3	0.011
Slfn4	schlafen 4	0.011
Gp1ba	glycoprotein 1b, alpha polypeptide	0.011
Rps5	ribosomal protein S5	0.011
Mcpt1	mast cell protease 1	0.011
Krt86	keratin 86	0.011
Ccl17	chemokine (C-C motif) ligand 17	0.011
Kcnk7	potassium channel, subfamily K, member 7	0.011
Galnt6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6	0.011
Ltk	leukocyte tyrosine kinase	0.011
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.011
Slfn1	schlafen 1	0.011
Lair1	leukocyte-associated Ig-like receptor 1	0.011
Krtap3-1	keratin associated protein 3-1	0.010
Sytl3	synaptotagmin-like 3	0.010
Pion	pigeon homolog (Drosophila)	0.010
Niacr1	niacin receptor 1	0.010
Tnfrsf14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.010
Olfr49	olfactory receptor 49	0.010
Muc13	mucin 13, epithelial transmembrane	0.010
Rgs9	regulator of G-protein signaling 9	0.010
Trat1	T cell receptor associated transmembrane adaptor 1	0.010
Slc6a20b	solute carrier family 6 (neurotransmitter transporter), member 20B	0.010