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Mus musculus

0 genes annotated in mouse

breast cancer

DOID:1612

A thoracic cancer that originates in the mammary gland.

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Gene Predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "breast cancer" (in gray)

Name	Description	Probability	Func Analog Organism
Pten	phosphatase and tensin homolog	0.985
Brca1	breast cancer 1	0.913
Brca2	breast cancer 2	0.763	Human
Mdm2	transformed mouse 3T3 cell double minute 2	0.374
Apc	adenomatosis polyposis coli	0.240
Cenpf	centromere protein F	0.220
Rb1	retinoblastoma 1	0.217
Nbn	nibrin	0.213
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.148	Human
Mybl2	myeloblastosis oncogene-like 2	0.131
Mdm4	transformed mouse 3T3 cell double minute 4	0.115
Prkdc	protein kinase, DNA activated, catalytic polypeptide	0.103
Sgol1	shugoshin-like 1 (S. pombe)	0.087
Stil	Scl/Tal1 interrupting locus	0.067
Chek1	checkpoint kinase 1 homolog (S. pombe)	0.060
Orc1	origin recognition complex, subunit 1	0.059
Mis18bp1	MIS18 binding protein 1	0.054
Mms22l	MMS22-like, DNA repair protein	0.051
Lig4	ligase IV, DNA, ATP-dependent	0.050
Lrr1	leucine rich repeat protein 1	0.050
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.049
Trp53	transformation related protein 53	0.048	Human
Ndc80	NDC80 homolog, kinetochore complex component (S. cerevisiae)	0.048
E2f1	E2F transcription factor 1	0.047
Atm	ataxia telangiectasia mutated homolog (human)	0.047	Human
Mnd1	meiotic nuclear divisions 1 homolog (S. cerevisiae)	0.046
Atr	ataxia telangiectasia and Rad3 related	0.045
Ccnd1	cyclin D1	0.045
Mki67	antigen identified by monoclonal antibody Ki 67	0.043
Cep55	centrosomal protein 55	0.042
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.041
Pik3cb	phosphatidylinositol 3-kinase, catalytic, beta polypeptide	0.040
Fancd2	Fanconi anemia, complementation group D2	0.039
Mpzl2	myelin protein zero-like 2	0.039
Dsn1	DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)	0.039
Blm	Bloom syndrome, RecQ helicase-like	0.039
Bub1b	budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)	0.038
Cenpe	centromere protein E	0.037
Akt2	thymoma viral proto-oncogene 2	0.036
Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2	0.035
Nuf2	NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.034
Rfwd2	ring finger and WD repeat domain 2	0.033
Ep300	E1A binding protein p300	0.033
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.031
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.031
Bod1l	biorientation of chromosomes in cell division 1-like	0.031
Esco2	establishment of cohesion 1 homolog 2 (S. cerevisiae)	0.030
Msh2	mutS homolog 2 (E. coli)	0.028
Mastl	microtubule associated serine/threonine kinase-like	0.028
Braf	Braf transforming gene	0.027
Melk	maternal embryonic leucine zipper kinase	0.026
Smc6	structural maintenance of chromosomes 6	0.026
Bub1	budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)	0.025
Pole	polymerase (DNA directed), epsilon	0.025
Wdhd1	WD repeat and HMG-box DNA binding protein 1	0.025
Cdca5	cell division cycle associated 5	0.025
Fadd	Fas (TNFRSF6)-associated via death domain	0.024
Fam111a	family with sequence similarity 111, member A	0.023
4632434I11Rik	RIKEN cDNA 4632434I11 gene	0.023
Gen1	Gen homolog 1, endonuclease (Drosophila)	0.023
Cenpn	centromere protein N	0.023
Rad51ap1	RAD51 associated protein 1	0.023
Sav1	salvador homolog 1 (Drosophila)	0.022
Kntc1	kinetochore associated 1	0.022
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.021
Raf1	v-raf-leukemia viral oncogene 1	0.021
2810417H13Rik	RIKEN cDNA 2810417H13 gene	0.021
Casc5	cancer susceptibility candidate 5	0.021
Mcm8	minichromosome maintenance deficient 8 (S. cerevisiae)	0.021
Pik3r3	phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)	0.021
Nfatc3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	0.021
Ripk3	receptor-interacting serine-threonine kinase 3	0.020
Shcbp1	Shc SH2-domain binding protein 1	0.020
Cenph	centromere protein H	0.020
Ncapg2	non-SMC condensin II complex, subunit G2	0.020
Fbxo5	F-box protein 5	0.020
Nf2	neurofibromatosis 2	0.020
Exo1	exonuclease 1	0.020
Ehmt2	euchromatic histone lysine N-methyltransferase 2	0.020
Ube3a	ubiquitin protein ligase E3A	0.019
Ect2	ect2 oncogene	0.019
Pbk	PDZ binding kinase	0.019
Trip13	thyroid hormone receptor interactor 13	0.019
Tmem30b	transmembrane protein 30B	0.019
Ckap2l	cytoskeleton associated protein 2-like	0.018
Chek2	CHK2 checkpoint homolog (S. pombe)	0.018	Human
Dmtf1	cyclin D binding myb-like transcription factor 1	0.018
Rad51c	RAD51 homolog c (S. cerevisiae)	0.018
Slc44a4	solute carrier family 44, member 4	0.018
Trp63	transformation related protein 63	0.018
Cdh1	cadherin 1	0.018	Human
Ttk	Ttk protein kinase	0.018
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.018
Dtl	denticleless homolog (Drosophila)	0.018
Txndc5	thioredoxin domain containing 5	0.017
Kif11	kinesin family member 11	0.017
F2rl1	coagulation factor II (thrombin) receptor-like 1	0.017
Ddx6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	0.017
Esrp2	epithelial splicing regulatory protein 2	0.017
Kif20b	kinesin family member 20B	0.017
Mlh1	mutL homolog 1 (E. coli)	0.016
Ncapg	non-SMC condensin I complex, subunit G	0.016
Rc3h1	RING CCCH (C3H) domains 1	0.016
Wdr1	WD repeat domain 1	0.016
Slc26a1	solute carrier family 26 (sulfate transporter), member 1	0.016
Irf6	interferon regulatory factor 6	0.016
Ikbkg	inhibitor of kappaB kinase gamma	0.016
Mbnl3	muscleblind-like 3 (Drosophila)	0.016
Kif18a	kinesin family member 18A	0.016
Diap3	diaphanous homolog 3 (Drosophila)	0.015
Errfi1	ERBB receptor feedback inhibitor 1	0.015
Rad54l	RAD54 like (S. cerevisiae)	0.015	Human
Rara	retinoic acid receptor, alpha	0.015
Wrn	Werner syndrome homolog (human)	0.015
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.015
Zfp322a	zinc finger protein 322A	0.015
F630043A04Rik	RIKEN cDNA F630043A04 gene	0.015
Sgol2	shugoshin-like 2 (S. pombe)	0.015
Spc25	SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.015
Tpx2	TPX2, microtubule-associated protein homolog (Xenopus laevis)	0.015
Stk4	serine/threonine kinase 4	0.014
Pms2	postmeiotic segregation increased 2 (S. cerevisiae)	0.014
Atad2	ATPase family, AAA domain containing 2	0.014
Ncaph	non-SMC condensin I complex, subunit H	0.014
Neil3	nei like 3 (E. coli)	0.014
Palb2	partner and localizer of BRCA2	0.014
Cenpj	centromere protein J	0.014
Cenpp	centromere protein P	0.014
Terf1	telomeric repeat binding factor 1	0.014
Bmi1	Bmi1 polycomb ring finger oncogene	0.014
Rint1	RAD50 interactor 1	0.014
Gins2	GINS complex subunit 2 (Psf2 homolog)	0.014
Lig1	ligase I, DNA, ATP-dependent	0.014
Gadd45a	growth arrest and DNA-damage-inducible 45 alpha	0.014
Men1	multiple endocrine neoplasia 1	0.014
Kif4	kinesin family member 4	0.014
Depdc1a	DEP domain containing 1a	0.014
Rnf8	ring finger protein 8	0.013
Mapk14	mitogen-activated protein kinase 14	0.013
Fam54a	family with sequence similarity 54, member A	0.013
Xpa	xeroderma pigmentosum, complementation group A	0.013
Cdca2	cell division cycle associated 2	0.013
Cdca7l	cell division cycle associated 7 like	0.013
Tsc1	tuberous sclerosis 1	0.013
Gsta2	glutathione S-transferase, alpha 2 (Yc2)	0.013
Kdm6a	4lysine (K)-specific demethylase 6A	0.013
Gins3	GINS complex subunit 3 (Psf3 homolog)	0.013
Alkbh1	alkB, alkylation repair homolog 1 (E. coli)	0.013
Mcm6	minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)	0.013
Myc	myelocytomatosis oncogene	0.013
Hells	helicase, lymphoid specific	0.013
Rrm2	ribonucleotide reductase M2	0.013
Med1	mediator complex subunit 1	0.013
Gas2l3	growth arrest-specific 2 like 3	0.012
Itga6	integrin alpha 6	0.012
Suv39h2	suppressor of variegation 3-9 homolog 2 (Drosophila)	0.012
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.012
Arid4a	AT rich interactive domain 4A (RBP1-like)	0.012
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.012
Ube2c	ubiquitin-conjugating enzyme E2C	0.012
Tmem194	transmembrane protein 194	0.012
Fbxw7	F-box and WD-40 domain protein 7	0.012
Fam33a	family with sequence similarity 33, member A	0.012
Cdcp1	CUB domain containing protein 1	0.012
Syce2	synaptonemal complex central element protein 2	0.012
Pdzk1ip1	PDZK1 interacting protein 1	0.012
Tmprss2	transmembrane protease, serine 2	0.012
Cenpw	centromere protein W	0.012
Eif2ak3	eukaryotic translation initiation factor 2 alpha kinase 3	0.012
Sult2b1	sulfotransferase family, cytosolic, 2B, member 1	0.012
D2Ertd750e	DNA segment, Chr 2, ERATO Doi 750, expressed	0.012
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.012
Pml	promyelocytic leukemia	0.012
Rsf1	remodeling and spacing factor 1	0.012
Nr1i2	nuclear receptor subfamily 1, group I, member 2	0.012
Tube1	epsilon-tubulin 1	0.012
Sp1	trans-acting transcription factor 1	0.012
Mcm5	minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)	0.012
Sfn	stratifin	0.012
Arpc4	actin related protein 2/3 complex, subunit 4	0.011
Spint2	serine protease inhibitor, Kunitz type 2	0.011
Clspn	claspin homolog (Xenopus laevis)	0.011
Aurkb	aurora kinase B	0.011
Wdr26	WD repeat domain 26	0.011
Mcm10	minichromosome maintenance deficient 10 (S. cerevisiae)	0.011
Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.011
Trim33	tripartite motif-containing 33	0.011
Fam83h	family with sequence similarity 83, member H	0.011
Sh3glb1	SH3-domain GRB2-like B1 (endophilin)	0.011
Prr11	proline rich 11	0.011
Ercc6l	excision repair cross-complementing rodent repair deficiency complementation group 6 - like	0.011
Tnfaip8l2	tumor necrosis factor, alpha-induced protein 8-like 2	0.011
Atad5	ATPase family, AAA domain containing 5	0.011
Sec31a	Sec31 homolog A (S. cerevisiae)	0.011
Msh6	mutS homolog 6 (E. coli)	0.011
Chd2	chromodomain helicase DNA binding protein 2	0.011
E2f7	E2F transcription factor 7	0.011
Mbd4	methyl-CpG binding domain protein 4	0.011
Max	Max protein	0.011
Eri2	exoribonuclease 2	0.011
Cenpk	centromere protein K	0.010
Fas	Fas (TNF receptor superfamily member 6)	0.010
Kitl	kit ligand	0.010
Ccna2	cyclin A2	0.010
Huwe1	HECT, UBA and WWE domain containing 1	0.010
Grb7	growth factor receptor bound protein 7	0.010
Ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.010
Rbbp8	retinoblastoma binding protein 8	0.010
Ehd4	EH-domain containing 4	0.010
Tgfbr1	transforming growth factor, beta receptor I	0.010
Foxo3	forkhead box O3	0.010
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.010
Smc2	structural maintenance of chromosomes 2	0.010
Ska1	spindle and kinetochore associated complex subunit 1	0.010
Lgals9	lectin, galactose binding, soluble 9	0.010
Zfyve16	zinc finger, FYVE domain containing 16	0.010
Mapkap1	mitogen-activated protein kinase associated protein 1	0.010
Hjurp	Holliday junction recognition protein	0.010
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.010
Tuft1	tuftelin 1	0.010
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.010
Parp16	poly (ADP-ribose) polymerase family, member 16	0.010
Akr1c13	aldo-keto reductase family 1, member C13	0.010