IMP

Process View

Mus musculus

4 genes annotated in mouse

cellular response to nitric oxide

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to nitric oxide"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cellular response to nitric oxide" (in gray)

Name	Description	Probability	Func Analog Organism
Mapk14	mitogen-activated protein kinase 14	1.000	Mouse
Atf2	activating transcription factor 2	0.962
Mapk11	mitogen-activated protein kinase 11	0.956	Mouse
Pten	phosphatase and tensin homolog	0.874
Cd40	CD40 antigen	0.760
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.707
Mdm2	transformed mouse 3T3 cell double minute 2	0.654
Trp53	transformation related protein 53	0.623
Mapkapk2	MAP kinase-activated protein kinase 2	0.560
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.460
Duox2	dual oxidase 2	0.421
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.355
Ikbkg	inhibitor of kappaB kinase gamma	0.247
Mapk8	mitogen-activated protein kinase 8	0.202
Mapk9	mitogen-activated protein kinase 9	0.174	Mouse
Mavs	mitochondrial antiviral signaling protein	0.171
Vhl	von Hippel-Lindau tumor suppressor	0.169
Spag9	sperm associated antigen 9	0.168
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.157
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.153
Ep300	E1A binding protein p300	0.152
Birc3	baculoviral IAP repeat-containing 3	0.108
Dusp2	dual specificity phosphatase 2	0.107
Notch1	Notch gene homolog 1 (Drosophila)	0.100
Prkce	protein kinase C, epsilon	0.090
Klc1	kinesin light chain 1	0.090
Igh	immunoglobulin heavy chain complex	0.088
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.087
Traf2	TNF receptor-associated factor 2	0.079
Irak3	interleukin-1 receptor-associated kinase 3	0.075
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.073
Rb1	retinoblastoma 1	0.071
Skil	SKI-like	0.064
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.062
Traf3ip2	TRAF3 interacting protein 2	0.061
Lox	lysyl oxidase	0.057
Map3k1	mitogen-activated protein kinase kinase kinase 1	0.056
Mdm4	transformed mouse 3T3 cell double minute 4	0.055
Traf6	TNF receptor-associated factor 6	0.052	Mouse
Trafd1	TRAF type zinc finger domain containing 1	0.051
Jun	Jun oncogene	0.049
Itch	itchy, E3 ubiquitin protein ligase	0.044
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.042
Fst	follistatin	0.041
Mfap5	microfibrillar associated protein 5	0.038
Wdfy2	WD repeat and FYVE domain containing 2	0.038
Amhr2	anti-Mullerian hormone type 2 receptor	0.038
Fbn1	fibrillin 1	0.036
Rbl2	retinoblastoma-like 2	0.036
Met	met proto-oncogene	0.036
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.035
Sav1	salvador homolog 1 (Drosophila)	0.035
Ptch1	patched homolog 1	0.034
Gripap1	GRIP1 associated protein 1	0.034
Col5a1	collagen, type V, alpha 1	0.033
Wwox	WW domain-containing oxidoreductase	0.033
Col3a1	collagen, type III, alpha 1	0.032
Crebbp	CREB binding protein	0.031
Cyr61	cysteine rich protein 61	0.031
Twist1	twist homolog 1 (Drosophila)	0.030
Vcl	vinculin	0.029
Stk11	serine/threonine kinase 11	0.029
Sharpin	SHANK-associated RH domain interacting protein	0.029
Map2k3	mitogen-activated protein kinase kinase 3	0.029
Npc1	Niemann Pick type C1	0.028
Col16a1	collagen, type XVI, alpha 1	0.028
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.027
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.027
Sun2	Sad1 and UNC84 domain containing 2	0.026
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.025
Mapk1	mitogen-activated protein kinase 1	0.025
Men1	multiple endocrine neoplasia 1	0.025
Rrad	Ras-related associated with diabetes	0.025
Efnb2	ephrin B2	0.025
Hif1a	hypoxia inducible factor 1, alpha subunit	0.025
Plaur	plasminogen activator, urokinase receptor	0.025
Chst8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8	0.025
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.024
Otud7b	OTU domain containing 7B	0.024
Mib1	mindbomb homolog 1 (Drosophila)	0.024
Mapk12	mitogen-activated protein kinase 12	0.024	Mouse
Osmr	oncostatin M receptor	0.024
Fbln2	fibulin 2	0.023
Col8a1	collagen, type VIII, alpha 1	0.023
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.022
Tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.022
Daxx	Fas death domain-associated protein	0.022
Tnc	tenascin C	0.021
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.021
Braf	Braf transforming gene	0.021
Thbs4	thrombospondin 4	0.020	Mouse
Mcm9	minichromosome maintenance complex component 9	0.020
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.020
Rarg	retinoic acid receptor, gamma	0.019
Fstl1	follistatin-like 1	0.019
Smad3	MAD homolog 3 (Drosophila)	0.019
Gsta4	glutathione S-transferase, alpha 4	0.018
Col5a2	collagen, type V, alpha 2	0.018
Lum	lumican	0.018
Map2k4	mitogen-activated protein kinase kinase 4	0.017
Rmnd5a	required for meiotic nuclear division 5 homolog A (S. cerevisiae)	0.017
Cpe	carboxypeptidase E	0.017
Ctsk	cathepsin K	0.017
Stk39	serine/threonine kinase 39, STE20/SPS1 homolog (yeast)	0.016
Rasal1	RAS protein activator like 1 (GAP1 like)	0.016
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.016
Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	0.016
Srpx	sushi-repeat-containing protein	0.016
Dclre1a	DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)	0.016
Dok1	docking protein 1	0.016
Mapkbp1	mitogen-activated protein kinase binding protein 1	0.016
Tle1	transducin-like enhancer of split 1, homolog of Drosophila E(spl)	0.016
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.016
Krtcap3	keratinocyte associated protein 3	0.016
Ap1m2	adaptor protein complex AP-1, mu 2 subunit	0.015
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.015
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.015
Tnip1	TNFAIP3 interacting protein 1	0.015
Nkx2-1	NK2 homeobox 1	0.015
Runx1	runt related transcription factor 1	0.015
Dlg1	discs, large homolog 1 (Drosophila)	0.014
Atf3	activating transcription factor 3	0.014
Col6a1	collagen, type VI, alpha 1	0.014
Adamts2	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2	0.014
Zfr2	zinc finger RNA binding protein 2	0.014
Pygm	muscle glycogen phosphorylase	0.014
Kitl	kit ligand	0.014
Etnk1	ethanolamine kinase 1	0.014
St14	suppression of tumorigenicity 14 (colon carcinoma)	0.014
Dsg4	desmoglein 4	0.014
Fut4	fucosyltransferase 4	0.013
Edar	ectodysplasin-A receptor	0.013
Eif2ak3	eukaryotic translation initiation factor 2 alpha kinase 3	0.013
Crb2	crumbs homolog 2 (Drosophila)	0.013
Rnf41	ring finger protein 41	0.013
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.013
Hnf1b	HNF1 homeobox B	0.013
Hes1	hairy and enhancer of split 1 (Drosophila)	0.013
Spsb1	splA/ryanodine receptor domain and SOCS box containing 1	0.013
Map3k3	mitogen-activated protein kinase kinase kinase 3	0.013
4932425I24Rik	RIKEN cDNA 4932425I24 gene	0.013
Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.013
Crlf1	cytokine receptor-like factor 1	0.013
1500015O10Rik	RIKEN cDNA 1500015O10 gene	0.013
Cdx1	caudal type homeobox 1	0.013
Bcl6	B-cell leukemia/lymphoma 6	0.013
Card11	caspase recruitment domain family, member 11	0.013
Eln	elastin	0.013
Fkbp10	FK506 binding protein 10	0.013
Chd2	chromodomain helicase DNA binding protein 2	0.012
Ripk2	receptor (TNFRSF)-interacting serine-threonine kinase 2	0.012
Kit	kit oncogene	0.012
Ikbke	inhibitor of kappaB kinase epsilon	0.012
Nrtn	neurturin	0.012
Helq	helicase, POLQ-like	0.012
Lmod1	leiomodin 1 (smooth muscle)	0.012
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.012
Egfl8	EGF-like domain 8	0.012
Srpx2	sushi-repeat-containing protein, X-linked 2	0.012
Aff1	AF4/FMR2 family, member 1	0.012
Angptl2	angiopoietin-like 2	0.012
Sfn	stratifin	0.012
Itgbl1	integrin, beta-like 1	0.012
Ahr	aryl-hydrocarbon receptor	0.012
Rps6ka5	ribosomal protein S6 kinase, polypeptide 5	0.012
Trp73	transformation related protein 73	0.012
Dpt	dermatopontin	0.012
Vax2	ventral anterior homeobox containing gene 2	0.012
Wwc1	WW, C2 and coiled-coil domain containing 1	0.012
Cbl	Casitas B-lineage lymphoma	0.012
Ager	advanced glycosylation end product-specific receptor	0.012
Ptgir	prostaglandin I receptor (IP)	0.012
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.011
Mfap4	microfibrillar-associated protein 4	0.011
Banp	BTG3 associated nuclear protein	0.011
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.011
Arhgap8	Rho GTPase activating protein 8	0.011
Nf2	neurofibromatosis 2	0.011
Msh2	mutS homolog 2 (E. coli)	0.011
Hipk1	homeodomain interacting protein kinase 1	0.011
Pdpn	podoplanin	0.011
Raf1	v-raf-leukemia viral oncogene 1	0.011
Ccdc85c	coiled-coil domain containing 85C	0.011
Mlph	melanophilin	0.011
Calcoco2	calcium binding and coiled-coil domain 2	0.011
Thra	thyroid hormone receptor alpha	0.011
Fam48a	family with sequence similarity 48, member A	0.011
Pim1	proviral integration site 1	0.011
Taf8	TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factorq	0.011
Flnc	filamin C, gamma	0.011
Rora	RAR-related orphan receptor alpha	0.010
Capn3	calpain 3	0.010
Il1r2	interleukin 1 receptor, type II	0.010
Ccdc136	coiled-coil domain containing 136	0.010
Rassf1	Ras association (RalGDS/AF-6) domain family member 1	0.010
Alms1	Alstrom syndrome 1 homolog (human)	0.010
Rapsn	receptor-associated protein of the synapse	0.010
Xpa	xeroderma pigmentosum, complementation group A	0.010
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.010
Corin	corin	0.010
Zfp28	zinc finger protein 28	0.010
Iqgap1	IQ motif containing GTPase activating protein 1	0.010
Myc	myelocytomatosis oncogene	0.010
Pofut1	protein O-fucosyltransferase 1	0.010