The network for 'regulation of leukocyte apoptotic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of leukocyte apoptotic process

Any process that modulates the frequency, rate or extent of leukocyte apoptotic process.

Mus musculus
Name Description Probability Func Analog Organism
Lyz2 lysozyme 2 0.999
Igh immunoglobulin heavy chain complex 0.996
Kit kit oncogene 0.952
Ptprc protein tyrosine phosphatase, receptor type, C 0.924
Cd44 CD44 antigen 0.912
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.907
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.877
Ccr1 chemokine (C-C motif) receptor 1 0.876
Lepr leptin receptor 0.860
Ikzf1 IKAROS family zinc finger 1 0.826
Il6st interleukin 6 signal transducer 0.806
Lck lymphocyte protein tyrosine kinase 0.787
Tlr4 toll-like receptor 4 0.747
Casp8 caspase 8 0.719
Ccl3 chemokine (C-C motif) ligand 3 0.718
Inpp5d inositol polyphosphate-5-phosphatase D 0.647
Ccr2 chemokine (C-C motif) receptor 2 0.640
Hif1a hypoxia inducible factor 1, alpha subunit 0.637
Il1r1 interleukin 1 receptor, type I 0.618
Tgfb1 transforming growth factor, beta 1 0.554
Ccl2 chemokine (C-C motif) ligand 2 0.538
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.516
Trp53 transformation related protein 53 0.516
Il2rg interleukin 2 receptor, gamma chain 0.495
Fas Fas (TNF receptor superfamily member 6) 0.494
Anxa4 annexin A4 0.487
H2-Eb1 histocompatibility 2, class II antigen E beta 0.478
Lep leptin 0.478
Rxra retinoid X receptor alpha 0.468
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.467
Klf6 Kruppel-like factor 6 0.435
Nfe2l2 nuclear factor, erythroid derived 2, like 2 0.415
Jak2 Janus kinase 2 0.411
Ccl8 chemokine (C-C motif) ligand 8 0.387
Gli3 GLI-Kruppel family member GLI3 0.382
Il2rb interleukin 2 receptor, beta chain 0.368
Pnp2 purine-nucleoside phosphorylase 2 0.352
Fcgr2b Fc receptor, IgG, low affinity IIb 0.345
Casp1 caspase 1 0.335
Dok1 docking protein 1 0.326
Meox2 mesenchyme homeobox 2 0.304
Stat5a signal transducer and activator of transcription 5A 0.299
Mdm4 transformed mouse 3T3 cell double minute 4 0.297
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.293
Itgal integrin alpha L 0.291
Ctsw cathepsin W 0.284
Csf1 colony stimulating factor 1 (macrophage) 0.279
Socs1 suppressor of cytokine signaling 1 0.272
Flt3 FMS-like tyrosine kinase 3 0.272
Tnf tumor necrosis factor 0.270
Ccr6 chemokine (C-C motif) receptor 6 0.265
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.265
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.256
Ncoa3 nuclear receptor coactivator 3 0.254
Cd96 CD96 antigen 0.253
Bcl2 B-cell leukemia/lymphoma 2 0.245
Socs3 suppressor of cytokine signaling 3 0.241
Stat5b signal transducer and activator of transcription 5B 0.231
Il1a interleukin 1 alpha 0.230
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.228
Pax3 paired box gene 3 0.227
Emx2 empty spiracles homolog 2 (Drosophila) 0.225
Rara retinoic acid receptor, alpha 0.225
Pparg peroxisome proliferator activated receptor gamma 0.218
Ptf1a pancreas specific transcription factor, 1a 0.216
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.216
Insr insulin receptor 0.215
Fos FBJ osteosarcoma oncogene 0.212
Fcgr1 Fc receptor, IgG, high affinity I 0.212
Irf9 interferon regulatory factor 9 0.210
Ccl9 chemokine (C-C motif) ligand 9 0.207
Csf2 colony stimulating factor 2 (granulocyte-macrophage) 0.206
C3ar1 complement component 3a receptor 1 0.203
Cxcl2 chemokine (C-X-C motif) ligand 2 0.201
Anxa1 annexin A1 0.199
Il1b interleukin 1 beta 0.192
Fgf15 fibroblast growth factor 15 0.188
Cd7 CD7 antigen 0.187
Ctnnb1 catenin (cadherin associated protein), beta 1 0.181
Il15 interleukin 15 0.180
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.179
Trp73 transformation related protein 73 0.178
Cd3e CD3 antigen, epsilon polypeptide 0.177
Mdfic MyoD family inhibitor domain containing 0.171
Foxf1a forkhead box F1a 0.163
Cd38 CD38 antigen 0.153
Pdcd1 programmed cell death 1 0.152
Egfr epidermal growth factor receptor 0.151
Ptch2 patched homolog 2 0.150
Ccr7 chemokine (C-C motif) receptor 7 0.150
Batf basic leucine zipper transcription factor, ATF-like 0.150
Fut7 fucosyltransferase 7 0.144
Jak3 Janus kinase 3 0.144
Wnt6 wingless-related MMTV integration site 6 0.143
Atxn1 ataxin 1 0.143
Zfp36 zinc finger protein 36 0.139
Pten phosphatase and tensin homolog 0.138
Litaf LPS-induced TN factor 0.136
Sh2d2a SH2 domain protein 2A 0.136
Bcl2l1 BCL2-like 1 0.136
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
SYK spleen tyrosine kinase 0.930
LCK lymphocyte-specific protein tyrosine kinase 0.922
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.857
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.854
BIRC3 baculoviral IAP repeat containing 3 0.846
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.830
CCR5 chemokine (C-C motif) receptor 5 0.787
TRAF1 TNF receptor-associated factor 1 0.706
CAV1 caveolin 1, caveolae protein, 22kDa 0.588
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.529
CCL4 chemokine (C-C motif) ligand 4 0.486
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.442
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.441
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.426
SH2D4A SH2 domain containing 4A 0.426
CCL5 chemokine (C-C motif) ligand 5 0.417
BCL2 B-cell CLL/lymphoma 2 0.373
IL10RA interleukin 10 receptor, alpha 0.357
CCR1 chemokine (C-C motif) receptor 1 0.351
CCR7 chemokine (C-C motif) receptor 7 0.343
BID BH3 interacting domain death agonist 0.300
BMPR1A bone morphogenetic protein receptor, type IA 0.298
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.263
CARD11 caspase recruitment domain family, member 11 0.258
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.240
TGIF1 TGFB-induced factor homeobox 1 0.226
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.204
PILRA paired immunoglobin-like type 2 receptor alpha 0.185
CD2 CD2 molecule 0.182
FASLG Fas ligand (TNF superfamily, member 6) 0.176
FAS Fas (TNF receptor superfamily, member 6) 0.175
CXCR4 chemokine (C-X-C motif) receptor 4 0.172
CD8A CD8a molecule 0.170
DLG1 discs, large homolog 1 (Drosophila) 0.165
CCL13 chemokine (C-C motif) ligand 13 0.162
CXCL9 chemokine (C-X-C motif) ligand 9 0.157
BIRC2 baculoviral IAP repeat containing 2 0.146
BAK1 BCL2-antagonist/killer 1 0.145
CFLAR CASP8 and FADD-like apoptosis regulator 0.134
MSN moesin 0.128
IL1B interleukin 1, beta 0.128
IL7R interleukin 7 receptor 0.127
PRKCZ protein kinase C, zeta 0.126
EP300 E1A binding protein p300 0.122
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.120
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.114
IL2RB interleukin 2 receptor, beta 0.110
IL2RG interleukin 2 receptor, gamma 0.110
CCL19 chemokine (C-C motif) ligand 19 0.110
BCL2L1 BCL2-like 1 0.109
IL8 interleukin 8 0.103
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.102
ICAM1 intercellular adhesion molecule 1 0.099
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.096
CD48 CD48 molecule 0.093
PTPRC protein tyrosine phosphatase, receptor type, C 0.086
NOXA1 NADPH oxidase activator 1 0.086
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.083
TRAF3 TNF receptor-associated factor 3 0.082
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.082
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.082
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.081
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 0.081
CCT8 chaperonin containing TCP1, subunit 8 (theta) 0.080
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.080
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) 0.077
SH3BP2 SH3-domain binding protein 2 0.077
VCAM1 vascular cell adhesion molecule 1 0.076
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.074
TRADD TNFRSF1A-associated via death domain 0.072
TNF tumor necrosis factor 0.068
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) 0.068
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.067
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.066
RIPK2 receptor-interacting serine-threonine kinase 2 0.065
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.064
INSR insulin receptor 0.063
HK3 hexokinase 3 (white cell) 0.062
PARD6A par-6 partitioning defective 6 homolog alpha (C. elegans) 0.062
CCL8 chemokine (C-C motif) ligand 8 0.062
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.061
C9orf89 chromosome 9 open reading frame 89 0.061
IL4R interleukin 4 receptor 0.059
CD83 CD83 molecule 0.059
IDE insulin-degrading enzyme 0.055
XIAP X-linked inhibitor of apoptosis 0.054
DERL1 Der1-like domain family, member 1 0.054
PLEK pleckstrin 0.053
EPOR erythropoietin receptor 0.051
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.051
LAT linker for activation of T cells 0.050
BCL2A1 BCL2-related protein A1 0.050
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.050
IL22RA1 interleukin 22 receptor, alpha 1 0.049
PARD6B par-6 partitioning defective 6 homolog beta (C. elegans) 0.048
MAGEA11 melanoma antigen family A, 11 0.048
IL10 interleukin 10 0.047
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.046
CDC37 cell division cycle 37 homolog (S. cerevisiae) 0.045
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.045
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Anxa2 annexin A2 0.406
RT1-DMb RT1 class II, locus DMb 0.090
Timp1 TIMP metallopeptidase inhibitor 1 0.077
Cd247 Cd247 molecule 0.070
RT1-Ba RT1 class II, locus Ba 0.064
Il2rb interleukin 2 receptor, beta 0.055
Gzmk granzyme K 0.041
Ripk3 receptor-interacting serine-threonine kinase 3 0.033
Lat linker for activation of T cells 0.031
Litaf lipopolysaccharide-induced TNF factor 0.028
Cd44 Cd44 molecule 0.028
Hmox1 heme oxygenase (decycling) 1 0.024
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.021
Racgap1 Rac GTPase-activating protein 1 0.021
Cd14 CD14 molecule 0.019
Capg capping protein (actin filament), gelsolin-like 0.019
Arpc1b actin related protein 2/3 complex, subunit 1B 0.018
Fam65b family with sequence similarity 65, member B 0.017
Pdpn podoplanin 0.016
Aif1 allograft inflammatory factor 1 0.015
Vcan versican 0.015
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.015
Tcrb T-cell receptor beta chain 0.013
LOC100361706 lambda-chain C1-region-like 0.012
Ccl2 chemokine (C-C motif) ligand 2 0.012
Cd8a CD8a molecule 0.011
Cd53 Cd53 molecule 0.011
Arhgap4 Rho GTPase activating protein 4 0.011
Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 0.010
Cd86 CD86 molecule 0.010
Sell selectin L 0.010
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism