IMP

Process View

Mus musculus

18 genes annotated in mouse

Multi-species View

regulation of defense response to virus

GO:0050688

Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of defense response to virus"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of defense response to virus" (in gray)

Name	Description	Probability	Func Analog Organism
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.997
Trim30a	tripartite motif-containing 30A	0.984	Mouse
Gbp7	guanylate binding protein 7	0.940	Mouse
Iigp1	interferon inducible GTPase 1	0.833
Ddx60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.820
Parp14	poly (ADP-ribose) polymerase family, member 14	0.788
Ikbkg	inhibitor of kappaB kinase gamma	0.781
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.706	Fly
Trim21	tripartite motif-containing 21	0.689
Ikbkb	inhibitor of kappaB kinase beta	0.684	Fly
Aim2	absent in melanoma 2	0.666
Ifi203	interferon activated gene 203	0.647	Mouse
Irgm1	immunity-related GTPase family M member 1	0.612
Igh	immunoglobulin heavy chain complex	0.607
Stat1	signal transducer and activator of transcription 1	0.599
Sp100	nuclear antigen Sp100	0.598
Stat3	signal transducer and activator of transcription 3	0.578
Gbp2	guanylate binding protein 2	0.550	Mouse
Mavs	mitochondrial antiviral signaling protein	0.526
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.516
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.487	Fly
Gbp3	guanylate binding protein 3	0.480	Mouse
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.427
Usp18	ubiquitin specific peptidase 18	0.427
Traf6	TNF receptor-associated factor 6	0.424	Mouse
Cd40	CD40 antigen	0.421
Uba7	ubiquitin-like modifier activating enzyme 7	0.412
Rsad2	radical S-adenosyl methionine domain containing 2	0.409
Mndal	myeloid nuclear differentiation antigen like	0.407
Myd88	myeloid differentiation primary response gene 88	0.393
Pycard	PYD and CARD domain containing	0.376
Tnf	tumor necrosis factor	0.374
Stat5b	signal transducer and activator of transcription 5B	0.366	Fly
Trim30d	tripartite motif-containing 30D	0.327	Mouse
Gbp10	guanylate-binding protein 10	0.310	Mouse
Pyhin1	pyrin and HIN domain family, member 1	0.295
Irf9	interferon regulatory factor 9	0.290	Mouse
Ifi44	interferon-induced protein 44	0.283
Rtp4	receptor transporter protein 4	0.274
Igtp	interferon gamma induced GTPase	0.270
Irgm2	immunity-related GTPase family M member 2	0.262
Gbp5	guanylate binding protein 5	0.252	Mouse
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.249
Irf1	interferon regulatory factor 1	0.237	Mouse
Trp53	transformation related protein 53	0.231
Cyld	cylindromatosis (turban tumor syndrome)	0.228
Ikzf1	IKAROS family zinc finger 1	0.216
Ifi47	interferon gamma inducible protein 47	0.213
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.212
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.196
Tgtp2	T-cell specific GTPase 2	0.189
Stat5a	signal transducer and activator of transcription 5A	0.181	Fly
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.179
Unc93b1	unc-93 homolog B1 (C. elegans)	0.174
Birc3	baculoviral IAP repeat-containing 3	0.168
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.165
Irf7	interferon regulatory factor 7	0.163	Mouse
Casp1	caspase 1	0.163	Fly
Samd9l	sterile alpha motif domain containing 9-like	0.154
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.154
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.145
Oasl2	2'-5' oligoadenylate synthetase-like 2	0.142
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.137
Ciita	class II transactivator	0.133
Gbp6	guanylate binding protein 6	0.129	Mouse
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.125
Ifih1	interferon induced with helicase C domain 1	0.124	Mouse
Mx1	myxovirus (influenza virus) resistance 1	0.113
Trim12a	tripartite motif-containing 12A	0.111	Mouse
Pml	promyelocytic leukemia	0.103	Human
D14Ertd668e	DNA segment, Chr 14, ERATO Doi 668, expressed	0.103
Lyz2	lysozyme 2	0.102
Dock2	dedicator of cyto-kinesis 2	0.102
Fas	Fas (TNF receptor superfamily member 6)	0.096
Ifit2	interferon-induced protein with tetratricopeptide repeats 2	0.096
Ifit1	interferon-induced protein with tetratricopeptide repeats 1	0.093	Human
Foxp3	forkhead box P3	0.092
Herc6	hect domain and RLD 6	0.086
Cd19	CD19 antigen	0.086
Sfpi1	SFFV proviral integration 1	0.085
Stat2	signal transducer and activator of transcription 2	0.079
Traf2	TNF receptor-associated factor 2	0.079	Mouse
Traf3	TNF receptor-associated factor 3	0.078
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.078
Bcl3	B-cell leukemia/lymphoma 3	0.076
Slfn8	schlafen 8	0.075
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.074
Samhd1	SAM domain and HD domain, 1	0.074
Csf1	colony stimulating factor 1 (macrophage)	0.072
Mnda	myeloid cell nuclear differentiation antigen	0.070
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.069
Zbp1	Z-DNA binding protein 1	0.069
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.068
Ddx58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.067	Human Mouse
Skil	SKI-like	0.066
Cmpk2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial	0.060
Tor3a	torsin family 3, member A	0.056
Dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58	0.054
Cxcl10	chemokine (C-X-C motif) ligand 10	0.051
Gvin1	GTPase, very large interferon inducible 1	0.048
Tax1bp1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.048
BC006779	cDNA sequence BC006779	0.047
Trim34a	tripartite motif-containing 34A	0.047	Mouse
Mx2	myxovirus (influenza virus) resistance 2	0.047
Nlrc5	NLR family, CARD domain containing 5	0.047
Cd72	CD72 antigen	0.046
Trim25	tripartite motif-containing 25	0.044
Ifi35	interferon-induced protein 35	0.044
AW112010	expressed sequence AW112010	0.041
Cflar	CASP8 and FADD-like apoptosis regulator	0.041
H2-T24	histocompatibility 2, T region locus 24	0.041
Dtx3l	deltex 3-like (Drosophila)	0.041
Jak3	Janus kinase 3	0.040
Il4ra	interleukin 4 receptor, alpha	0.038
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.038
Nmi	N-myc (and STAT) interactor	0.038
Vav1	vav 1 oncogene	0.037
Ctss	cathepsin S	0.037
Znfx1	zinc finger, NFX1-type containing 1	0.037
Epsti1	epithelial stromal interaction 1 (breast)	0.036
Irf4	interferon regulatory factor 4	0.035	Mouse
Trim12c	tripartite motif-containing 12C	0.035	Mouse
Oas1b	2'-5' oligoadenylate synthetase 1B	0.034
Ticam1	toll-like receptor adaptor molecule 1	0.033
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.033
Parp9	poly (ADP-ribose) polymerase family, member 9	0.031
C920025E04Rik	RIKEN cDNA C920025E04 gene	0.029
Ltb	lymphotoxin B	0.029
Il1r1	interleukin 1 receptor, type I	0.029
Map4k1	mitogen-activated protein kinase kinase kinase kinase 1	0.029
Daxx	Fas death domain-associated protein	0.028
Serpinb9	serine (or cysteine) peptidase inhibitor, clade B, member 9	0.028
Rnf31	ring finger protein 31	0.028
Gbp4	guanylate binding protein 4	0.028
Il10	interleukin 10	0.027
Ncoa3	nuclear receptor coactivator 3	0.027
Sykb	spleen tyrosine kinase	0.026
Smad6	MAD homolog 6 (Drosophila)	0.026
Cd180	CD180 antigen	0.025
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.025
Ms4a6b	membrane-spanning 4-domains, subfamily A, member 6B	0.025
Cd79b	CD79B antigen	0.025
H2-M3	histocompatibility 2, M region locus 3	0.024
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.024
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.024
Prlr	prolactin receptor	0.024
2010106G01Rik	RIKEN cDNA 2010106G01 gene	0.023
Axin1	axin 1	0.023
Trim5	tripartite motif-containing 5	0.023	Mouse
Ifnar1	interferon (alpha and beta) receptor 1	0.023
Tmc6	transmembrane channel-like gene family 6	0.023
Card11	caspase recruitment domain family, member 11	0.022
Ccr2	chemokine (C-C motif) receptor 2	0.022
Il10ra	interleukin 10 receptor, alpha	0.022
Prkcd	protein kinase C, delta	0.022
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.022
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.021
Oas2	2'-5' oligoadenylate synthetase 2	0.021
Trafd1	TRAF type zinc finger domain containing 1	0.021
Tcf3	transcription factor 3	0.020
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.020
Ubc	ubiquitin C	0.019
Cd274	CD274 antigen	0.019
Csprs	component of Sp100-rs	0.019
Irf8	interferon regulatory factor 8	0.018	Mouse
Cd27	CD27 antigen	0.018
Nlrp3	NLR family, pyrin domain containing 3	0.018
Irf5	interferon regulatory factor 5	0.018	Mouse
Ogn	osteoglycin	0.018
Xaf1	XIAP associated factor 1	0.018
Ilk	integrin linked kinase	0.018
Pparg	peroxisome proliferator activated receptor gamma	0.018
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.018
Tmem64	transmembrane protein 64	0.017
H2-Q7	histocompatibility 2, Q region locus 7	0.017
Ube2l6	ubiquitin-conjugating enzyme E2L 6	0.017
Lrmp	lymphoid-restricted membrane protein	0.017
Aicda	activation-induced cytidine deaminase	0.017
Socs1	suppressor of cytokine signaling 1	0.017
Oas3	2'-5' oligoadenylate synthetase 3	0.016
Zc3hav1	zinc finger CCCH type, antiviral 1	0.016	Human
Il6st	interleukin 6 signal transducer	0.016
Il16	interleukin 16	0.016
Foxn1	forkhead box N1	0.015
Il27ra	interleukin 27 receptor, alpha	0.015
Blnk	B-cell linker	0.015
Trp53bp1	transformation related protein 53 binding protein 1	0.015
Suds3	suppressor of defective silencing 3 homolog (S. cerevisiae)	0.015
Rac1	RAS-related C3 botulinum substrate 1	0.015
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.015
Slfn2	schlafen 2	0.014
Btk	Bruton agammaglobulinemia tyrosine kinase	0.014
Cxcl9	chemokine (C-X-C motif) ligand 9	0.014
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.014
H2-Q8	histocompatibility 2, Q region locus 8	0.014
Gbp1	guanylate binding protein 1	0.014
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.014
Tlr3	toll-like receptor 3	0.014
Slfn4	schlafen 4	0.014
Ifi27l2a	interferon, alpha-inducible protein 27 like 2A	0.014
Ifi204	interferon activated gene 204	0.013
Clk2	CDC-like kinase 2	0.013
Apbb1ip	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	0.013
Kcnn4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	0.013
Tlr4	toll-like receptor 4	0.013
Sqstm1	sequestosome 1	0.013
Fadd	Fas (TNFRSF6)-associated via death domain	0.013
Il12b	interleukin 12b	0.013
Podxl	podocalyxin-like	0.013
Adar	adenosine deaminase, RNA-specific	0.013
Mrpl3	mitochondrial ribosomal protein L3	0.013
Casp8	caspase 8	0.013
Rrad	Ras-related associated with diabetes	0.013
AI607873	expressed sequence AI607873	0.013
Tlr7	toll-like receptor 7	0.013
Ccl4	chemokine (C-C motif) ligand 4	0.012
Vegfa	vascular endothelial growth factor A	0.012
Itga4	integrin alpha 4	0.012
Clec2d	C-type lectin domain family 2, member d	0.012
Batf	basic leucine zipper transcription factor, ATF-like	0.012
Il2ra	interleukin 2 receptor, alpha chain	0.012
Rnf135	ring finger protein 135	0.012
Il2rg	interleukin 2 receptor, gamma chain	0.012
Il2rb	interleukin 2 receptor, beta chain	0.012
Pou2f2	POU domain, class 2, transcription factor 2	0.011
Nckap1l	NCK associated protein 1 like	0.011
Prkci	protein kinase C, iota	0.011
Prf1	perforin 1 (pore forming protein)	0.011
Ghr	growth hormone receptor	0.011
BC017643	cDNA sequence BC017643	0.011
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.011
Il23a	interleukin 23, alpha subunit p19	0.011
Was	Wiskott-Aldrich syndrome homolog (human)	0.011
Insr	insulin receptor	0.011
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.011
Il10rb	interleukin 10 receptor, beta	0.011
Sharpin	SHANK-associated RH domain interacting protein	0.011
Kit	kit oncogene	0.011
Otud7b	OTU domain containing 7B	0.011
Lcp2	lymphocyte cytosolic protein 2	0.010
Ccr7	chemokine (C-C motif) receptor 7	0.010
Gimap4	GTPase, IMAP family member 4	0.010
Tapbpl	TAP binding protein-like	0.010
Ikzf3	IKAROS family zinc finger 3	0.010
Lta	lymphotoxin A	0.010
Il2	interleukin 2	0.010
Tlr6	toll-like receptor 6	0.010
Diap1	diaphanous homolog 1 (Drosophila)	0.010