IMP

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Mus musculus

25 genes annotated in mouse

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defense response to protozoan

GO:0042832

Reactions triggered in response to the presence of a protozoan that act to protect the cell or organism.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "defense response to protozoan"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "defense response to protozoan" (in gray)

Name	Description	Probability	Func Analog Organism
Igtp	interferon gamma induced GTPase	1.000	Mouse
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.997
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.996
Gbp7	guanylate binding protein 7	0.995
Irgm2	immunity-related GTPase family M member 2	0.980
Iigp1	interferon inducible GTPase 1	0.978
Gbp2	guanylate binding protein 2	0.966
Tgtp2	T-cell specific GTPase 2	0.959	Mouse
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.959
Ifi47	interferon gamma inducible protein 47	0.948	Mouse
Irgm1	immunity-related GTPase family M member 1	0.947	Mouse
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.933
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.927	Mouse
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.914
Stat1	signal transducer and activator of transcription 1	0.910
Uba7	ubiquitin-like modifier activating enzyme 7	0.870
Trim21	tripartite motif-containing 21	0.829
Fas	Fas (TNF receptor superfamily member 6)	0.788
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.785	Mouse
Gbp3	guanylate binding protein 3	0.763
Gbp6	guanylate binding protein 6	0.731
Irf1	interferon regulatory factor 1	0.687	Mouse
Tnf	tumor necrosis factor	0.685
Casp1	caspase 1	0.670
Bcl3	B-cell leukemia/lymphoma 3	0.635
Irf9	interferon regulatory factor 9	0.585	Mouse
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.572
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.570
Stat6	signal transducer and activator of transcription 6	0.562
Cxcl10	chemokine (C-X-C motif) ligand 10	0.530
Aim2	absent in melanoma 2	0.509
Il4ra	interleukin 4 receptor, alpha	0.508
Sfpi1	SFFV proviral integration 1	0.492
Socs1	suppressor of cytokine signaling 1	0.490
Cxcl9	chemokine (C-X-C motif) ligand 9	0.483
Irf4	interferon regulatory factor 4	0.467
Zbp1	Z-DNA binding protein 1	0.421
Stat2	signal transducer and activator of transcription 2	0.400
Foxp3	forkhead box P3	0.391
Stat3	signal transducer and activator of transcription 3	0.387
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.381
Il10	interleukin 10	0.356
Parp14	poly (ADP-ribose) polymerase family, member 14	0.354
Trim30a	tripartite motif-containing 30A	0.346
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.342
Lyz2	lysozyme 2	0.317
Cd40	CD40 antigen	0.316
Psmb8	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	0.268
Pycard	PYD and CARD domain containing	0.262
Mmp9	matrix metallopeptidase 9	0.252
Gbp10	guanylate-binding protein 10	0.244
Irf8	interferon regulatory factor 8	0.230
Birc3	baculoviral IAP repeat-containing 3	0.228
Ifit1	interferon-induced protein with tetratricopeptide repeats 1	0.207
Batf	basic leucine zipper transcription factor, ATF-like	0.205
Rag1	recombination activating gene 1	0.174
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.167
Ifi203	interferon activated gene 203	0.163
Parp9	poly (ADP-ribose) polymerase family, member 9	0.163
Il10ra	interleukin 10 receptor, alpha	0.161
Isg15	ISG15 ubiquitin-like modifier	0.155
Cd274	CD274 antigen	0.150
Irf5	interferon regulatory factor 5	0.124	Mouse
AW112010	expressed sequence AW112010	0.123
Dock2	dedicator of cyto-kinesis 2	0.121
Prf1	perforin 1 (pore forming protein)	0.113
Igh	immunoglobulin heavy chain complex	0.110
Il1r1	interleukin 1 receptor, type I	0.109
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.108
Il4	interleukin 4	0.107
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.106
Cd28	CD28 antigen	0.098
Tgfb1	transforming growth factor, beta 1	0.094
Serpina3g	serine (or cysteine) peptidase inhibitor, clade A, member 3G	0.091
Tlr4	toll-like receptor 4	0.091
Ptgs2	prostaglandin-endoperoxide synthase 2	0.090
Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.089	Mouse
Ifih1	interferon induced with helicase C domain 1	0.087
Itgb2	integrin beta 2	0.085
Oasl2	2'-5' oligoadenylate synthetase-like 2	0.084
H2-M3	histocompatibility 2, M region locus 3	0.082
Bcl6	B-cell leukemia/lymphoma 6	0.079
Ifng	interferon gamma	0.078
Samhd1	SAM domain and HD domain, 1	0.078
Ccl4	chemokine (C-C motif) ligand 4	0.076
Kit	kit oncogene	0.074
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.074
Pdcd1	programmed cell death 1	0.073
Tfrc	transferrin receptor	0.073
Tapbp	TAP binding protein	0.073
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.072
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.071
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.069
1810019J16Rik	RIKEN cDNA 1810019J16 gene	0.068
Ncf1	neutrophil cytosolic factor 1	0.068
Il21r	interleukin 21 receptor	0.066
Prkcd	protein kinase C, delta	0.066
Socs3	suppressor of cytokine signaling 3	0.063
BC006779	cDNA sequence BC006779	0.063
Csf1	colony stimulating factor 1 (macrophage)	0.062
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.059
Ccl2	chemokine (C-C motif) ligand 2	0.059
Itga3	integrin alpha 3	0.059
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.058
2010106G01Rik	RIKEN cDNA 2010106G01 gene	0.058
Nphs2	nephrosis 2 homolog, podocin (human)	0.057
Podxl	podocalyxin-like	0.057
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.056
Usp18	ubiquitin specific peptidase 18	0.054
Mx2	myxovirus (influenza virus) resistance 2	0.053
Bcl2	B-cell leukemia/lymphoma 2	0.053
H2-Q7	histocompatibility 2, Q region locus 7	0.052
Rtp4	receptor transporter protein 4	0.052
Mitf	microphthalmia-associated transcription factor	0.051
Inpp5d	inositol polyphosphate-5-phosphatase D	0.051
Cmpk2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial	0.049
Cd19	CD19 antigen	0.049
Il1b	interleukin 1 beta	0.049
Lcp2	lymphocyte cytosolic protein 2	0.047
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.045
Mndal	myeloid nuclear differentiation antigen like	0.045
Hbb-b1	hemoglobin, beta adult major chain	0.044
Jak3	Janus kinase 3	0.044
Mefv	Mediterranean fever	0.044
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.043
Ciita	class II transactivator	0.041
Tor3a	torsin family 3, member A	0.041
Prkci	protein kinase C, iota	0.040
Ifit2	interferon-induced protein with tetratricopeptide repeats 2	0.038
Ptgir	prostaglandin I receptor (IP)	0.038
Slc24a5	solute carrier family 24, member 5	0.037
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.035
H2-Q8	histocompatibility 2, Q region locus 8	0.035
Cd180	CD180 antigen	0.035
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.034
Itgal	integrin alpha L	0.034
Gbp4	guanylate binding protein 4	0.033	Mouse
Rac2	RAS-related C3 botulinum substrate 2	0.033
Dtx3l	deltex 3-like (Drosophila)	0.033
Nmi	N-myc (and STAT) interactor	0.032
Ube2l6	ubiquitin-conjugating enzyme E2L 6	0.031
Cybb	cytochrome b-245, beta polypeptide	0.031
Gbp8	guanylate-binding protein 8	0.029	Mouse
Tnip1	TNFAIP3 interacting protein 1	0.029
C1ra	complement component 1, r subcomponent A	0.029
Ncf4	neutrophil cytosolic factor 4	0.028
Mvp	major vault protein	0.028
Rab27a	RAB27A, member RAS oncogene family	0.028
Icam1	intercellular adhesion molecule 1	0.027
Il2rb	interleukin 2 receptor, beta chain	0.027
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.027
Ifi35	interferon-induced protein 35	0.027
Sp100	nuclear antigen Sp100	0.027
Nlrp3	NLR family, pyrin domain containing 3	0.027
Cd86	CD86 antigen	0.026
Ccl5	chemokine (C-C motif) ligand 5	0.026
Nos2	nitric oxide synthase 2, inducible	0.025
Tapbpl	TAP binding protein-like	0.025
Gvin1	GTPase, very large interferon inducible 1	0.025
Serpinb9	serine (or cysteine) peptidase inhibitor, clade B, member 9	0.024
Ikzf1	IKAROS family zinc finger 1	0.024
Lama5	laminin, alpha 5	0.024
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.024
Rel	reticuloendotheliosis oncogene	0.024
Irg1	immunoresponsive gene 1	0.024
Tbxas1	thromboxane A synthase 1, platelet	0.023
Gbp9	guanylate-binding protein 9	0.023
Traf1	TNF receptor-associated factor 1	0.023
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.023	Mouse
Samd9l	sterile alpha motif domain containing 9-like	0.023
Hps1	Hermansky-Pudlak syndrome 1 homolog (human)	0.023
Gimap4	GTPase, IMAP family member 4	0.022
Trim30d	tripartite motif-containing 30D	0.022
Ebi3	Epstein-Barr virus induced gene 3	0.021
Sykb	spleen tyrosine kinase	0.021
Ly9	lymphocyte antigen 9	0.021
Stx11	syntaxin 11	0.020
Trim34a	tripartite motif-containing 34A	0.020
Runx1	runt related transcription factor 1	0.020
D14Ertd668e	DNA segment, Chr 14, ERATO Doi 668, expressed	0.020
Pyhin1	pyrin and HIN domain family, member 1	0.020
Psmb10	proteasome (prosome, macropain) subunit, beta type 10	0.020
Exoc6	exocyst complex component 6	0.019
Irf7	interferon regulatory factor 7	0.019	Mouse
Il27ra	interleukin 27 receptor, alpha	0.019
Cst7	cystatin F (leukocystatin)	0.019
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.019
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.019
Ccrl2	chemokine (C-C motif) receptor-like 2	0.019
Hmox1	heme oxygenase (decycling) 1	0.019
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.019
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.018
Trp53	transformation related protein 53	0.018
Oas2	2'-5' oligoadenylate synthetase 2	0.018
Rsad2	radical S-adenosyl methionine domain containing 2	0.018
Ccr5	chemokine (C-C motif) receptor 5	0.018
H2-Q5	histocompatibility 2, Q region locus 5	0.018
Znfx1	zinc finger, NFX1-type containing 1	0.018
Uros	uroporphyrinogen III synthase	0.018
Apbb1ip	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	0.018
Sh2b3	SH2B adaptor protein 3	0.017
Gm14548	predicted gene 14548	0.017
Dnase1l3	deoxyribonuclease 1-like 3	0.017
BC013712	cDNA sequence BC013712	0.017
Ifi44	interferon-induced protein 44	0.017
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.017
Slfn1	schlafen 1	0.017
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.017
Wt1	Wilms tumor 1 homolog	0.017
Gzmb	granzyme B	0.017
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.017
Il3	interleukin 3	0.017
Ifnar2	interferon (alpha and beta) receptor 2	0.016
Prkag1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.016
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.016
Arid5a	AT rich interactive domain 5A (MRF1-like)	0.016
Il10rb	interleukin 10 receptor, beta	0.016
H2-Oa	histocompatibility 2, O region alpha locus	0.016
C920025E04Rik	RIKEN cDNA C920025E04 gene	0.016
Slc15a3	solute carrier family 15, member 3	0.016
Rhoh	ras homolog gene family, member H	0.016
Saa3	serum amyloid A 3	0.016
Mx1	myxovirus (influenza virus) resistance 1	0.015
Cd80	CD80 antigen	0.015
Gbp1	guanylate binding protein 1	0.015
Cflar	CASP8 and FADD-like apoptosis regulator	0.015
Pou2f2	POU domain, class 2, transcription factor 2	0.015
Selp	selectin, platelet	0.015
Lag3	lymphocyte-activation gene 3	0.015
Btk	Bruton agammaglobulinemia tyrosine kinase	0.015
Tgm2	transglutaminase 2, C polypeptide	0.014
Ccr2	chemokine (C-C motif) receptor 2	0.014
Laptm5	lysosomal-associated protein transmembrane 5	0.014
Plekho2	pleckstrin homology domain containing, family O member 2	0.014
Vegfa	vascular endothelial growth factor A	0.014
Epb4.1	erythrocyte protein band 4.1	0.014
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.014
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.013
Madcam1	mucosal vascular addressin cell adhesion molecule 1	0.013
Parp10	poly (ADP-ribose) polymerase family, member 10	0.013
Il1r2	interleukin 1 receptor, type II	0.013
Nlrc5	NLR family, CARD domain containing 5	0.013
Srgn	serglycin	0.013
Mnda	myeloid cell nuclear differentiation antigen	0.013
C5ar1	complement component 5a receptor 1	0.012
Tmem173	transmembrane protein 173	0.012
Sell	selectin, lymphocyte	0.012
Tnfrsf18	tumor necrosis factor receptor superfamily, member 18	0.012
Slfn2	schlafen 2	0.012
Plxna1	plexin A1	0.012
Grip1	glutamate receptor interacting protein 1	0.012
Adam8	a disintegrin and metallopeptidase domain 8	0.012
Evi2a	ecotropic viral integration site 2a	0.012
Cyld	cylindromatosis (turban tumor syndrome)	0.012
Ccr7	chemokine (C-C motif) receptor 7	0.012
Cd74	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)	0.012
Mov10	Moloney leukemia virus 10	0.012
Snx20	sorting nexin 20	0.012
Myd88	myeloid differentiation primary response gene 88	0.012
Ap3b1	adaptor-related protein complex 3, beta 1 subunit	0.012
Erap1	endoplasmic reticulum aminopeptidase 1	0.011
Cp	ceruloplasmin	0.011
H2-DMa	histocompatibility 2, class II, locus DMa	0.011
F7	coagulation factor VII	0.011
Il6st	interleukin 6 signal transducer	0.011
Herc6	hect domain and RLD 6	0.011
St3gal1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	0.011
Fgd3	FYVE, RhoGEF and PH domain containing 3	0.011
Tap1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.011
Il3ra	interleukin 3 receptor, alpha chain	0.011
Dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58	0.011
Gpr132	G protein-coupled receptor 132	0.011
Ikbke	inhibitor of kappaB kinase epsilon	0.011
Mpeg1	macrophage expressed gene 1	0.011
Fcgr1	Fc receptor, IgG, high affinity I	0.010
Ikbkb	inhibitor of kappaB kinase beta	0.010
Ccl8	chemokine (C-C motif) ligand 8	0.010
Aoah	acyloxyacyl hydrolase	0.010