The network for 'pattern specification process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

pattern specification process

Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate.

Name Description Probability Func Analog Organism
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1.000
TP53 tumor protein p53 0.999
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.994
HDAC1 histone deacetylase 1 0.982
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.970
SMAD3 SMAD family member 3 0.970
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.965
SMAD2 SMAD family member 2 0.963
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.916
DDX3X DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked 0.847
NOTCH1 notch 1 0.827
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.811
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.808
RHOA ras homolog gene family, member A 0.801
MAPK8 mitogen-activated protein kinase 8 0.799
RB1 retinoblastoma 1 0.798
EGFR epidermal growth factor receptor 0.775
SP1 Sp1 transcription factor 0.668
JAG1 jagged 1 0.666
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.662
FGFR2 fibroblast growth factor receptor 2 0.603
GSK3B glycogen synthase kinase 3 beta 0.594
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.573
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.538
FLNA filamin A, alpha 0.532
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.524
HOXB5 homeobox B5 0.501
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.499
MYH9 myosin, heavy chain 9, non-muscle 0.489
JUN jun proto-oncogene 0.449
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.403
NKX2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.402
SMAD4 SMAD family member 4 0.397
SMAD1 SMAD family member 1 0.386
FOXD3 forkhead box D3 0.386
VEGFA vascular endothelial growth factor A 0.383
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.376
PDX1 pancreatic and duodenal homeobox 1 0.374
TP73 tumor protein p73 0.361
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.358
COL4A2 collagen, type IV, alpha 2 0.350
ZHX1 zinc fingers and homeoboxes 1 0.345
BTRC beta-transducin repeat containing 0.342
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.340
CDC27 cell division cycle 27 homolog (S. cerevisiae) 0.338
RING1 ring finger protein 1 0.333
GATA4 GATA binding protein 4 0.327
QKI quaking homolog, KH domain RNA binding (mouse) 0.324
MAPT microtubule-associated protein tau 0.319
PAX1 paired box 1 0.314
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.304
SMAD7 SMAD family member 7 0.297
PTBP1 polypyrimidine tract binding protein 1 0.291
AR androgen receptor 0.286
RBBP8 retinoblastoma binding protein 8 0.283
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.272
PCGF2 polycomb group ring finger 2 0.271
PBX1 pre-B-cell leukemia homeobox 1 0.265
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.253
PRKCZ protein kinase C, zeta 0.249
PKM2 pyruvate kinase, muscle 0.246
BCL2 B-cell CLL/lymphoma 2 0.243
SKIL SKI-like oncogene 0.242
USP11 ubiquitin specific peptidase 11 0.236
BMPR1A bone morphogenetic protein receptor, type IA 0.235
APC adenomatous polyposis coli 0.234
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 0.230
PABPC1 poly(A) binding protein, cytoplasmic 1 0.230
LBX1 ladybird homeobox 1 0.228
ATXN1 ataxin 1 0.223
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.222
FGFR1 fibroblast growth factor receptor 1 0.222
ZNF512B zinc finger protein 512B 0.216
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.215
MAPK1 mitogen-activated protein kinase 1 0.208
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.207
IQGAP1 IQ motif containing GTPase activating protein 1 0.206
ELAVL1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.203
HOXB9 homeobox B9 0.202
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.201
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.198
ZYX zyxin 0.198
FHL2 four and a half LIM domains 2 0.196
ANAPC5 anaphase promoting complex subunit 5 0.195
TCF4 transcription factor 4 0.194
KEAP1 kelch-like ECH-associated protein 1 0.194
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 0.192
ESR1 estrogen receptor 1 0.191
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.182
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.179
RBBP4 retinoblastoma binding protein 4 0.179
SMAD6 SMAD family member 6 0.172
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.169
BRCA1 breast cancer 1, early onset 0.168
SFN stratifin 0.166
FOXA2 forkhead box A2 0.160
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.160
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.160
MAP2K1 mitogen-activated protein kinase kinase 1 0.160
NRP1 neuropilin 1 0.159
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
pha-4 Protein PHA-4 0.980
vab-3 Protein VAB-3 0.965
egl-18 Protein EGL-18 0.962
unc-62 Protein UNC-62 0.939
elt-6 Protein ELT-6 0.778
che-13 Protein CHE-13 0.727
nhr-67 Protein NHR-67 0.694
klp-15 Protein KLP-15 0.635
mab-5 Protein MAB-5 0.598
hlh-2 Protein HLH-2 0.587
che-2 Protein CHE-2 0.545
egl-46 Protein EGL-46 0.544
pal-1 Protein PAL-1 0.516
bar-1 Protein BAR-1 0.512
lin-17 Protein LIN-17 0.400
osm-5 Protein OSM-5 0.378
egl-13 Protein EGL-13 0.366
let-60 Protein LET-60 0.332
sma-6 Protein SMA-6 0.331
hnd-1 Protein HND-1 0.327
xpo-1 Protein XPO-1 0.309
eor-1 Protein EOR-1 0.307
che-3 Protein CHE-3 0.303
let-756 Protein LET-756 0.303
aqp-2 Protein AQP-2 0.303
inx-3 Protein INX-3 0.302
unc-6 Protein UNC-6 0.296
unc-86 Protein UNC-86 0.289
cam-1 Protein CAM-1 0.274
inx-13 Protein INX-13 0.267
unc-73 Protein UNC-73 0.260
egl-44 Protein EGL-44 0.256
mec-2 Protein MEC-2 0.249
lin-11 Protein LIN-11 0.249
pry-1 Protein PRY-1 0.245
ceh-27 Protein CEH-27 0.245
che-11 Protein CHE-11 0.243
F39B2.1 Protein F39B2.1 0.242
mat-3 Protein MAT-3 0.238
hlh-1 Protein HLH-1 0.230
ain-1 Protein AIN-1 0.229
inx-4 Protein INX-4 0.222
ajm-1 Protein AJM-1 0.217
mnp-1 Protein MNP-1 0.214
lmn-1 Protein LMN-1 0.211
odd-2 Protein ODD-2 0.210
atg-2 Protein ATG-2 0.210
mel-11 Protein MEL-11 0.198
zfp-1 Protein ZFP-1 0.198
rgs-7 Protein RGS-7 0.197
pqn-89 Protein PQN-89 0.196
fkh-2 Protein FKH-2 0.191
nhr-25 Protein NHR-25 0.190
lin-66 Protein LIN-66 0.189
tag-53 Protein TAG-53 0.187
ceh-36 Protein CEH-36 0.185
lin-29 Protein LIN-29 0.184
mdt-29 Protein MDT-29 0.183
lntl-1 Protein LNTL-1 0.177
ceh-13 Protein CEH-13 0.176
pdfr-1 Protein PDFR-1 0.176
nlg-1 Protein NLG-1 0.173
unc-32 Protein UNC-32 0.173
F21A10.2 Protein F21A10.2 0.170
gpb-2 Protein GPB-2 0.167
daf-10 Protein DAF-10 0.167
R10E12.2 Protein R10E12.2 0.166
tbx-8 Protein TBX-8 0.165
trim-9 Protein TRIM-9 0.162
pkg-1 Protein PKG-1 0.154
fbxc-32 Protein FBXC-32 0.151
hsr-9 Protein HSR-9 0.150
klf-2 Protein KLF-2 0.149
goa-1 Protein GOA-1 0.146
spk-1 Protein SPK-1 0.146
osm-6 Protein OSM-6 0.144
pop-1 Protein POP-1 0.144
egl-5 Protein EGL-5 0.144
lin-12 Protein LIN-12 0.143
wrm-1 Protein WRM-1 0.142
ten-1 Protein TEN-1 0.141
mbk-2 Protein MBK-2 0.139
sup-12 Protein SUP-12 0.138
unc-98 Protein UNC-98 0.134
F47G3.3 Protein F47G3.3 0.134
R02F11.4 Protein R02F11.4 0.132
set-1 Protein SET-1 0.132
che-14 Protein CHE-14 0.129
sea-2 Protein SEA-2 0.128
vav-1 Protein VAV-1 0.128
glp-1 Protein GLP-1 0.128
apr-1 Protein APR-1 0.127
pat-3 Protein PAT-3 0.126
glh-4 Protein GLH-4 0.123
egl-30 Protein EGL-30 0.120
eat-16 Protein EAT-16 0.119
F59F4.3 Protein F59F4.3 0.118
zen-4 Protein ZEN-4 0.118
unc-42 Protein UNC-42 0.118
syd-2 Protein SYD-2 0.117
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.018
Lamc1 laminin, gamma 1 0.011
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism