The network for 'positive regulation of mapk cascade' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of mapk cascade

Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.

Mus musculus
Name Description Probability Func Analog Organism
Grb2 growth factor receptor bound protein 2 1.000
Src Rous sarcoma oncogene 0.997
Lepr leptin receptor 0.996
Vangl2 vang-like 2 (van gogh, Drosophila) 0.996
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.996
Inpp5d inositol polyphosphate-5-phosphatase D 0.995
Pten phosphatase and tensin homolog 0.995
Tnf tumor necrosis factor 0.995
Cav1 caveolin 1, caveolae protein 0.993
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.993
Btk Bruton agammaglobulinemia tyrosine kinase 0.992
Csf1 colony stimulating factor 1 (macrophage) 0.992
Apc adenomatosis polyposis coli 0.992
Cbl Casitas B-lineage lymphoma 0.992
Traf6 TNF receptor-associated factor 6 0.984
Mmp9 matrix metallopeptidase 9 0.984
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.982
Cd44 CD44 antigen 0.969
Dvl2 dishevelled 2, dsh homolog (Drosophila) 0.968
Nos3 nitric oxide synthase 3, endothelial cell 0.966
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.959
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.948
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.947
Apoe apolipoprotein E 0.946
Cd40 CD40 antigen 0.942
Egfr epidermal growth factor receptor 0.936
Dok1 docking protein 1 0.934
Ptk2 PTK2 protein tyrosine kinase 2 0.933
Ccl2 chemokine (C-C motif) ligand 2 0.926
Nodal nodal 0.925
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.924
Prkce protein kinase C, epsilon 0.924
Vdr vitamin D receptor 0.917
Plcg1 phospholipase C, gamma 1 0.907
Insr insulin receptor 0.906
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.905
Nos1 nitric oxide synthase 1, neuronal 0.902
Fas Fas (TNF receptor superfamily member 6) 0.888
Tgfb2 transforming growth factor, beta 2 0.888
Prrx1 paired related homeobox 1 0.882
Il10 interleukin 10 0.880
Sema3f sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.878
Igh immunoglobulin heavy chain complex 0.878
Chrd chordin 0.875
Psen1 presenilin 1 0.871
Axin1 axin 1 0.864
Ret ret proto-oncogene 0.863
Acvr1 activin A receptor, type 1 0.861
Efnb2 ephrin B2 0.860
Cd22 CD22 antigen 0.858
Lyz2 lysozyme 2 0.855
Fgfr2 fibroblast growth factor receptor 2 0.853
Ccr2 chemokine (C-C motif) receptor 2 0.851
Fyn Fyn proto-oncogene 0.850
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.849
Tbx2 T-box 2 0.848
Ephb2 Eph receptor B2 0.845
Wnt3a wingless-related MMTV integration site 3A 0.845
Dab1 disabled homolog 1 (Drosophila) 0.844
Ntf3 neurotrophin 3 0.832
Notch1 Notch gene homolog 1 (Drosophila) 0.827
Ptk7 PTK7 protein tyrosine kinase 7 0.822
Shc1 src homology 2 domain-containing transforming protein C1 0.819
Cdon cell adhesion molecule-related/down-regulated by oncogenes 0.818
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.815
Grb10 growth factor receptor bound protein 10 0.814
Wnt5a wingless-related MMTV integration site 5A 0.814
Esr1 estrogen receptor 1 (alpha) 0.803
Myd88 myeloid differentiation primary response gene 88 0.800
Lep leptin 0.794
Pnpla2 patatin-like phospholipase domain containing 2 0.793
Fras1 Fraser syndrome 1 homolog (human) 0.793
Jag1 jagged 1 0.787
Kl klotho 0.787
Fgfr1 fibroblast growth factor receptor 1 0.764
Il1r1 interleukin 1 receptor, type I 0.761
Ifng interferon gamma 0.757
Fgf10 fibroblast growth factor 10 0.752
Il6st interleukin 6 signal transducer 0.747
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.736
Stat3 signal transducer and activator of transcription 3 0.729
Axl AXL receptor tyrosine kinase 0.726
Bdnf brain derived neurotrophic factor 0.723
Hoxa1 homeobox A1 0.717
Shh sonic hedgehog 0.715
Adam17 a disintegrin and metallopeptidase domain 17 0.714
Nos2 nitric oxide synthase 2, inducible 0.713
Gab1 growth factor receptor bound protein 2-associated protein 1 0.711
Adrb1 adrenergic receptor, beta 1 0.709
Tenc1 tensin like C1 domain-containing phosphatase 0.694
Ghr growth hormone receptor 0.688
Ephb3 Eph receptor B3 0.686
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.677
Il6 interleukin 6 0.675
Flt4 FMS-like tyrosine kinase 4 0.675
Mapk8 mitogen-activated protein kinase 8 0.674
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.673
Tgfbr2 transforming growth factor, beta receptor II 0.670
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.669
Nf1 neurofibromatosis 1 0.668
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
msp-55 Protein MSP-55 0.491
bar-1 Protein BAR-1 0.369
msp-77 Protein MSP-77 0.357
msp-10 Protein MSP-10 0.287
msp-142 Protein MSP-142 0.276
mpk-1 Protein MPK-1 0.269
msp-49 Protein MSP-49 0.229
msp-53 Protein MSP-53 0.215
msp-59 Protein MSP-59 0.196
msp-3 Protein MSP-3 0.194
msp-76 Protein MSP-76 0.175
ZK1248.17 Protein ZK1248.17 0.175
msp-40 Protein MSP-40 0.161
zoo-1 Protein ZOO-1 0.144
msp-36 Protein MSP-36 0.143
K08E3.5 Protein K08E3.5 0.142
msp-78 Protein MSP-78 0.139
nhr-6 Protein NHR-6 0.135
lin-25 Protein LIN-25 0.135
msp-45 Protein MSP-45 0.125
msp-38 Protein MSP-38 0.124
msp-152 Protein MSP-152 0.113
msp-79 Protein MSP-79 0.112
mek-2 Protein MEK-2 0.109
msp-33 Protein MSP-33 0.101
egl-18 Protein EGL-18 0.092
sma-6 Protein SMA-6 0.089
lin-45 Protein LIN-45 0.087
dpy-22 Protein DPY-22 0.081
msp-74 Protein MSP-74 0.081
sem-5 Protein SEM-5 0.068
cst-1 Protein CST-1 0.062
itr-1 Protein ITR-1 0.062
msp-64 Protein MSP-64 0.060
msp-19 Protein MSP-19 0.056
let-60 Protein LET-60 0.051
msp-50 Protein MSP-50 0.048
lin-29 Protein LIN-29 0.043
lin-36 Protein LIN-36 0.043
let-756 Protein LET-756 0.039
msp-31 Protein MSP-31 0.038
F26B1.2 Protein F26B1.2 0.038
hrpf-1 Protein HRPF-1 0.037
msp-32 Protein MSP-32 0.036
tps-1 Protein TPS-1 0.036
F39B2.1 Protein F39B2.1 0.035
chd-7 Protein CHD-7 0.033
msp-51 Protein MSP-51 0.033
rpm-1 Protein RPM-1 0.033
ncam-1 Protein NCAM-1 0.032
Y59H11AM.1 Protein Y59H11AM.1 0.031
ham-1 Protein HAM-1 0.031
sax-7 Protein SAX-7 0.030
patr-1 Protein PATR-1 0.030
ZK546.3 Protein ZK546.3 0.030
msp-65 Protein MSP-65 0.029
F58A6.9 Protein F58A6.9 0.029
unc-40 Protein UNC-40 0.029
pkn-1 Protein PKN-1 0.029
sym-4 Protein SYM-4 0.028
msp-63 Protein MSP-63 0.028
mig-5 Protein MIG-5 0.028
clh-5 Protein CLH-5 0.027
zfp-3 Protein ZFP-3 0.027
gei-18 Protein GEI-18 0.026
egl-15 Protein EGL-15 0.026
npp-7 Protein NPP-7 0.026
tax-6 Protein TAX-6 0.025
lin-53 Protein LIN-53 0.024
abl-1 Protein ABL-1 0.023
cst-2 Protein CST-2 0.023
daf-19 Protein DAF-19 0.023
lat-1 Protein LAT-1 0.022
unc-18 Protein UNC-18 0.022
eps-8 Protein EPS-8 0.022
ceh-44 Protein CEH-44 0.022
obr-3 Protein OBR-3 0.021
hmg-1.2 Protein HMG-1.2 0.020
K07H8.2 Protein K07H8.2 0.020
CELE_Y59E9AR.7 Protein Y59E9AR.7 0.020
sma-10 Protein SMA-10 0.020
Y43H11AL.1 Protein Y43H11AL.1 0.020
daf-14 Protein DAF-14 0.020
cam-1 Protein CAM-1 0.019
plc-3 Protein PLC-3 0.019
rgs-6 Protein RGS-6 0.019
ten-1 Protein TEN-1 0.019
btbd-10 Protein BTBD-10 0.019
zer-1 Protein ZER-1 0.019
unc-94 Protein UNC-94 0.019
trim-9 Protein TRIM-9 0.018
let-19 Protein LET-19 0.018
ksr-1 Protein KSR-1 0.017
T23G5.2 Protein T23G5.2 0.017
xbx-6 Protein XBX-6 0.017
plc-1 Protein PLC-1 0.016
toca-1 Protein TOCA-1 0.016
guk-1 Protein GUK-1 0.016
sma-1 Protein SMA-1 0.016
sur-2 Protein SUR-2 0.016
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
phl pole hole 0.692
Ras85D Ras oncogene at 85D 0.300
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.268
fz frizzled 0.259
Liprin-alpha CG11199 gene product from transcript CG11199-RB 0.259
rl rolled 0.197
aop anterior open 0.194
Rac2 CG8556 gene product from transcript CG8556-RA 0.191
pnut peanut 0.184
ed echinoid 0.159
Mad Mothers against dpp 0.143
Jra Jun-related antigen 0.141
Akt1 CG4006 gene product from transcript CG4006-RA 0.134
lqf liquid facets 0.125
msn misshapen 0.123
Atg1 Autophagy-specific gene 1 0.115
chico CG5686 gene product from transcript CG5686-RB 0.114
NetB Netrin-B 0.110
Gug Grunge 0.105
ovo CG6824 gene product from transcript CG6824-RE 0.104
trio CG18214 gene product from transcript CG18214-RA 0.103
btl breathless 0.100
Gap1 GTPase-activating protein 1 0.100
Rab5 Rab-protein 5 0.100
bsk basket 0.098
stck steamer duck 0.097
drk downstream of receptor kinase 0.097
Dad Daughters against dpp 0.097
mtt mangetout 0.094
Cip4 CG15015 gene product from transcript CG15015-RA 0.094
Rcd1 Reduction in Cnn dots 1 0.093
spi spitz 0.090
Lis-1 Lissencephaly-1 0.086
Med Medea 0.086
kay kayak 0.085
LIMK1 LIM-kinase1 0.084
tamo CG4057 gene product from transcript CG4057-RA 0.083
mei-41 meiotic 41 0.082
Cdc42 CG12530 gene product from transcript CG12530-RA 0.079
dco discs overgrown 0.079
wg wingless 0.079
par-1 CG8201 gene product from transcript CG8201-RA 0.078
Rheb CG1081 gene product from transcript CG1081-RA 0.078
CkIIalpha Casein kinase II alpha subunit 0.077
dock dreadlocks 0.076
l(1)G0232 lethal (1) G0232 0.076
Smox Smad on X 0.075
Smg1 CG32743 gene product from transcript CG32743-RA 0.070
Hph HIF prolyl hydroxylase 0.067
Dsor1 Downstream of raf1 0.065
Nrx-IV Neurexin IV 0.065
hep hemipterous 0.064
Cbl CG7037 gene product from transcript CG7037-RB 0.064
ft fat 0.063
fred friend of echinoid 0.062
Vps35 Vacuolar protein sorting 35 0.062
fl(2)d female lethal d 0.061
S6kII RPS6-protein kinase-II 0.059
mbc myoblast city 0.058
Stat92E Signal-transducer and activator of transcription protein at 92E 0.058
Plc21C Phospholipase C at 21C 0.056
cbs centrosomin's beautiful sister 0.054
Shc SHC-adaptor protein 0.054
ci cubitus interruptus 0.054
CG7028 CG7028 gene product from transcript CG7028-RA 0.051
X11L CG5675 gene product from transcript CG5675-RB 0.051
ex expanded 0.051
ecd ecdysoneless 0.051
drpr draper 0.050
Fcp1 CG12252 gene product from transcript CG12252-RA 0.050
Nrx-1 Neurexin 1 0.048
milt milton 0.048
G-oalpha47A G protein oalpha 47A 0.048
SF1 Splicing factor 1 0.048
InR Insulin-like receptor 0.048
Grip Glutamate receptor binding protein 0.048
scb scab 0.047
dm diminutive 0.047
Gyc76C Guanylyl cyclase at 76C 0.047
Lar Leukocyte-antigen-related-like 0.047
Tl Toll 0.046
Sry-beta Serendipity beta 0.046
CkIalpha Casein kinase Ialpha 0.046
dgo diego 0.046
bun bunched 0.046
myoglianin CG1838 gene product from transcript CG1838-RD 0.046
Toll-7 CG8595 gene product from transcript CG8595-RA 0.045
CG9894 CG9894 gene product from transcript CG9894-RB 0.045
shot short stop 0.044
sr stripe 0.044
lin lines 0.043
Mcm6 Minichromosome maintenance 6 0.043
ird1 immune response deficient 1 0.041
mask multiple ankyrin repeats single KH domain 0.041
Pp1alpha-96A Protein phosphatase 1alpha at 96A 0.041
CG8159 CG8159 gene product from transcript CG8159-RB 0.041
pyr pyramus 0.041
Dab Disabled 0.040
Sra-1 specifically Rac1-associated protein 1 0.040
Myd88 CG2078 gene product from transcript CG2078-RA 0.040
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Homo sapiens
Name Description Probability Func Analog Organism
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.000
EGFR epidermal growth factor receptor 1.000
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 1.000
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1.000
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
CAV1 caveolin 1, caveolae protein, 22kDa 1.000
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.999
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.999
SFN stratifin 0.999
SH3KBP1 SH3-domain kinase binding protein 1 0.998
TRAF1 TNF receptor-associated factor 1 0.998
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.998
FN1 fibronectin 1 0.998
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.996
TRAF6 TNF receptor-associated factor 6 0.996
GAB1 GRB2-associated binding protein 1 0.996
FGFR1 fibroblast growth factor receptor 1 0.995
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.995
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.995
GRB2 growth factor receptor-bound protein 2 0.994
FGFR2 fibroblast growth factor receptor 2 0.994
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.994
TRAF2 TNF receptor-associated factor 2 0.993
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.993
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.992
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.992
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.992
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.992
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.990
CCR5 chemokine (C-C motif) receptor 5 0.989
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.988
LRRK2 leucine-rich repeat kinase 2 0.986
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.986
MET met proto-oncogene (hepatocyte growth factor receptor) 0.984
SQSTM1 sequestosome 1 0.983
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.979
SMAD2 SMAD family member 2 0.977
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.974
LAT linker for activation of T cells 0.972
TEK TEK tyrosine kinase, endothelial 0.972
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.971
SMAD7 SMAD family member 7 0.964
ESR1 estrogen receptor 1 0.964
PRKCA protein kinase C, alpha 0.962
BCAR1 breast cancer anti-estrogen resistance 1 0.962
IRAK1 interleukin-1 receptor-associated kinase 1 0.956
TGFB1 transforming growth factor, beta 1 0.954
BIRC3 baculoviral IAP repeat containing 3 0.950
CSNK1E casein kinase 1, epsilon 0.948
IGF1R insulin-like growth factor 1 receptor 0.946
GSK3B glycogen synthase kinase 3 beta 0.935
FAS Fas (TNF receptor superfamily, member 6) 0.929
ERBB2IP erbb2 interacting protein 0.928
SMAD3 SMAD family member 3 0.927
NCK1 NCK adaptor protein 1 0.918
IL6 interleukin 6 (interferon, beta 2) 0.915
MAPK14 mitogen-activated protein kinase 14 0.913
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.912
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.912
FGF1 fibroblast growth factor 1 (acidic) 0.911
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.911
PTEN phosphatase and tensin homolog 0.910
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.909
ENG endoglin 0.902
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.902
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.898
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.898
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.897
MAP3K1 mitogen-activated protein kinase kinase kinase 1 0.895
WASL Wiskott-Aldrich syndrome-like 0.887
MAPK1 mitogen-activated protein kinase 1 0.886
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.883
PDPK1 3-phosphoinositide dependent protein kinase-1 0.879
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.866
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.854
BMPR1A bone morphogenetic protein receptor, type IA 0.852
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.851
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.850
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.846
FYN FYN oncogene related to SRC, FGR, YES 0.845
CCL22 chemokine (C-C motif) ligand 22 0.843
NRP1 neuropilin 1 0.841
DLG1 discs, large homolog 1 (Drosophila) 0.840
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.832
IL1R1 interleukin 1 receptor, type I 0.829
CFLAR CASP8 and FADD-like apoptosis regulator 0.814
AXL AXL receptor tyrosine kinase 0.806
IRAK2 interleukin-1 receptor-associated kinase 2 0.802
MAPK8 mitogen-activated protein kinase 8 0.800
BRAF v-raf murine sarcoma viral oncogene homolog B1 0.796
TNF tumor necrosis factor 0.776
PRKCZ protein kinase C, zeta 0.773
VEGFA vascular endothelial growth factor A 0.768
CD40 CD40 molecule, TNF receptor superfamily member 5 0.757
PAX3 paired box 3 0.755
BBS10 Bardet-Biedl syndrome 10 0.745
CD28 CD28 molecule 0.738
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.734
SMAD4 SMAD family member 4 0.728
IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) 0.727
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Rattus norvegicus
Name Description Probability Func Analog Organism
Il1a interleukin 1 alpha 0.493
Adora2a adenosine A2a receptor 0.420
Met met proto-oncogene 0.373
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.372
Fgfr2 fibroblast growth factor receptor 2 0.363
Ptafr platelet-activating factor receptor 0.328
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.317
Cx3cr1 chemokine (C-X3-C motif) receptor 1 0.299
Ednra endothelin receptor type A 0.293
Inpp5d inositol polyphosphate-5-phosphatase D 0.282
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.281
Cdh6 cadherin 6 0.281
Mr1 major histocompatibility complex, class I-related 0.267
Itgam integrin, alpha M 0.262
Nab1 Ngfi-A binding protein 1 0.260
Oprm1 opioid receptor, mu 1 0.259
Gna15 guanine nucleotide binding protein, alpha 15 0.249
Utrn utrophin 0.244
Prdm2 PR domain containing 2, with ZNF domain 0.243
Cd4 Cd4 molecule 0.237
Ncan neurocan 0.228
Itpkb inositol 1,4,5-trisphosphate 3-kinase B 0.222
Fgf7 fibroblast growth factor 7 0.221
Cd38 CD38 molecule 0.216
Lepr leptin receptor 0.214
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.212
Ccr2 chemokine (C-C motif) receptor 2 0.204
Tgfbr3 transforming growth factor, beta receptor III 0.199
Il2rg interleukin 2 receptor, gamma 0.197
Olfml2b olfactomedin-like 2B 0.194
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.193
Bcan brevican 0.185
Ccl4 chemokine (C-C motif) ligand 4 0.185
Bdkrb2 bradykinin receptor B2 0.182
Grm5 glutamate receptor, metabotropic 5 0.180
Il10ra interleukin 10 receptor, alpha 0.177
Mapk1 mitogen activated protein kinase 1 0.171
Rgs12 regulator of G-protein signaling 12 0.168
Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 0.166
Ptpn7 protein tyrosine phosphatase, non-receptor type 7 0.166
Mpeg1 macrophage expressed 1 0.165
Tcf21 transcription factor 21 0.161
Insr insulin receptor 0.158
Svs1 seminal vesicle secretory protein 1 0.157
Irs1 insulin receptor substrate 1 0.156
Syt10 synaptotagmin X 0.152
Tgfbr2 transforming growth factor, beta receptor II 0.150
Ptger2 prostaglandin E receptor 2 (subtype EP2) 0.146
Psp parotid secretory protein 0.143
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.143
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.139
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.137
Tcf4 transcription factor 4 0.135
Kitlg KIT ligand 0.131
Ctsj cathepsin J 0.131
Musk muscle, skeletal, receptor tyrosine kinase 0.128
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.127
Axl Axl receptor tyrosine kinase 0.127
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) 0.127
Synpo synaptopodin 0.126
Agtr1a angiotensin II receptor, type 1a 0.126
Ncr1 natural cytotoxicity triggering receptor 1 0.125
Egfr epidermal growth factor receptor 0.123
Slc1a3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.121
Ednrb endothelin receptor type B 0.119
Il9r interleukin 9 receptor 0.115
Hck hemopoietic cell kinase 0.115
Trhr thyrotropin releasing hormone receptor 0.114
Cbl Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.113
Scn4a sodium channel, voltage-gated, type IV, alpha subunit 0.111
Vdr vitamin D (1,25- dihydroxyvitamin D3) receptor 0.111
Jtb jumping translocation breakpoint 0.110
Gjb4 gap junction protein, beta 4 0.110
Grm7 glutamate receptor, metabotropic 7 0.109
RGD1564664 similar to LOC387763 protein 0.107
Ar androgen receptor 0.107
Vom2r27 vomeronasal 2 receptor, 27 0.106
Smad7 SMAD family member 7 0.105
Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.103
Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 0.102
Rab10 RAB10, member RAS oncogene family 0.102
Cxcr5 chemokine (C-X-C motif) receptor 5 0.102
Lphn2 latrophilin 2 0.102
Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 0.100
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.100
Chrna7 cholinergic receptor, nicotinic, alpha 7 0.099
Slc7a2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 0.099
Il1rap interleukin 1 receptor accessory protein 0.099
Slc8a2 solute carrier family 8 (sodium/calcium exchanger), member 2 0.099
Notch3 Notch homolog 3 (Drosophila) 0.098
Shc1 SHC (Src homology 2 domain containing) transforming protein 1 0.096
Sstr5 somatostatin receptor 5 0.096
Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N 0.095
Neurog3 neurogenin 3 0.095
Cntn3 contactin 3 (plasmacytoma associated) 0.094
Hpca hippocalcin 0.094
Chrm1 cholinergic receptor, muscarinic 1 0.093
Phkg1 phosphorylase kinase, gamma 1 0.092
Gpr6 G protein-coupled receptor 6 0.092
Vegp2 von Ebners gland protein 2 0.092
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
SSK2 Ssk2p 0.996
PBS2 Pbs2p 0.992
SSK1 Ssk1p 0.972
FUS3 Fus3p 0.780
BMH1 Bmh1p 0.555
SNT1 Snt1p 0.457
STE4 Ste4p 0.370
STE5 Ste5p 0.346
SSK22 Ssk22p 0.261
HOS4 Hos4p 0.179
HOS2 Hos2p 0.165
MSG5 Msg5p 0.165
ZDS1 Zds1p 0.146
GIC1 Gic1p 0.124
HST1 Hst1p 0.097
FUS1 Fus1p 0.093
RGD1 Rgd1p 0.079
BCK1 Bck1p 0.077
SHP1 Shp1p 0.065
CDC34 Cdc34p 0.064
RHO1 Rho1p 0.051
NBP2 Nbp2p 0.047
AKL1 Akl1p 0.046
SIF2 Sif2p 0.036
AHP1 Ahp1p 0.034
GIC2 Gic2p 0.034
STE7 Ste7p 0.033
SKP1 Skp1p 0.032
KIC1 Kic1p 0.031
PRS2 Prs2p 0.030
CPR1 Cpr1p 0.029
SGD1 Sgd1p 0.029
HOG1 Hog1p 0.028
RGD2 Rgd2p 0.025
STE2 Ste2p 0.024
ASH1 Ash1p 0.024
MKK1 Mkk1p 0.022
IRA1 Ira1p 0.021
BCK2 Bck2p 0.021
KSS1 Kss1p 0.020
KDX1 Kdx1p 0.019
SBH1 Sbh1p 0.019
UFO1 Ufo1p 0.019
TEC1 Tec1p 0.018
SLT2 Slt2p 0.018
SUT1 Sut1p 0.017
STE20 Ste20p 0.017
GYL1 Gyl1p 0.016
BIT61 Bit61p 0.016
TAT1 Tat1p 0.015
ATG14 Atg14p 0.015
PKC1 Pkc1p 0.014
DBF2 Dbf2p 0.014
SRD1 Srd1p 0.014
YJR085C hypothetical protein 0.014
ISR1 Isr1p 0.013
RRP36 Rrp36p 0.013
CTF13 Ctf13p 0.013
ARP10 Arp10p 0.012
CUP1-1 Cup1-1p 0.012
YLR264C-A hypothetical protein 0.012
PTI1 Pti1p 0.012
AQR1 Aqr1p 0.012
PRP28 Prp28p 0.012
ADH2 Adh2p 0.012
DIA2 Dia2p 0.011
YLR162W hypothetical protein 0.010
YOL038C-A hypothetical protein 0.010