Process View
The network for 'maternal placenta development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Tgfbr2 | transforming growth factor, beta receptor II | 0.998 | |
Pten | phosphatase and tensin homolog | 0.989 | |
Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.977 | |
Bmp4 | bone morphogenetic protein 4 | 0.954 | |
Fgfr2 | fibroblast growth factor receptor 2 | 0.879 | |
Foxc1 | forkhead box C1 | 0.868 | |
Csf1 | colony stimulating factor 1 (macrophage) | 0.830 | |
Esr1 | estrogen receptor 1 (alpha) | 0.790 | |
Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.752 | |
Nos3 | nitric oxide synthase 3, endothelial cell | 0.743 | |
Vegfa | vascular endothelial growth factor A | 0.740 | |
Apc | adenomatosis polyposis coli | 0.701 | |
Bmp7 | bone morphogenetic protein 7 | 0.694 | |
Mapk8 | mitogen-activated protein kinase 8 | 0.607 | |
Fgfr3 | fibroblast growth factor receptor 3 | 0.595 | |
Smad4 | MAD homolog 4 (Drosophila) | 0.521 | |
Foxh1 | forkhead box H1 | 0.492 | |
Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.486 | |
Sox9 | SRY-box containing gene 9 | 0.464 | |
Smad3 | MAD homolog 3 (Drosophila) | 0.456 | |
Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.447 | |
Egr1 | early growth response 1 | 0.428 | |
Col1a1 | collagen, type I, alpha 1 | 0.412 | |
Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.354 | |
Pparg | peroxisome proliferator activated receptor gamma | 0.332 | |
Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.330 | |
Tgfbr1 | transforming growth factor, beta receptor I | 0.318 | |
Runx2 | runt related transcription factor 2 | 0.286 | |
Bmp2 | bone morphogenetic protein 2 | 0.280 | |
Fos | FBJ osteosarcoma oncogene | 0.265 | |
Tgfb2 | transforming growth factor, beta 2 | 0.260 | |
Esr2 | estrogen receptor 2 (beta) | 0.253 | |
Rarg | retinoic acid receptor, gamma | 0.229 | |
Meox2 | mesenchyme homeobox 2 | 0.216 | |
Pitx2 | paired-like homeodomain transcription factor 2 | 0.185 | |
Lepr | leptin receptor | 0.180 | |
Ptch1 | patched homolog 1 | 0.177 | |
Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.162 | |
Fgfr1 | fibroblast growth factor receptor 1 | 0.154 | |
Gsk3b | glycogen synthase kinase 3 beta | 0.145 | |
Smo | smoothened homolog (Drosophila) | 0.141 | |
Vhl | von Hippel-Lindau tumor suppressor | 0.138 | |
Msx2 | homeobox, msh-like 2 | 0.135 | |
Ghr | growth hormone receptor | 0.134 | |
Nos2 | nitric oxide synthase 2, inducible | 0.131 | |
Ldb3 | LIM domain binding 3 | 0.120 | |
Acvr1 | activin A receptor, type 1 | 0.118 | |
Notch2 | Notch gene homolog 2 (Drosophila) | 0.116 | |
Cav1 | caveolin 1, caveolae protein | 0.116 | |
Il2rg | interleukin 2 receptor, gamma chain | 0.115 | |
Pax2 | paired box gene 2 | 0.115 | |
Shh | sonic hedgehog | 0.112 | |
Ctsd | cathepsin D | 0.112 | |
Hnrnpk | heterogeneous nuclear ribonucleoprotein K | 0.110 | |
Ece1 | endothelin converting enzyme 1 | 0.108 | |
Rarb | retinoic acid receptor, beta | 0.094 | |
Tnfsf11 | tumor necrosis factor (ligand) superfamily, member 11 | 0.093 | |
Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.093 | |
Bmper | BMP-binding endothelial regulator | 0.093 | |
Egfr | epidermal growth factor receptor | 0.089 | |
Nr2f2 | nuclear receptor subfamily 2, group F, member 2 | 0.085 | |
Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.084 | |
Rxra | retinoid X receptor alpha | 0.082 | |
Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.080 | |
Fus | fusion, derived from t(12;16) malignant liposarcoma (human) | 0.079 | |
Nf1 | neurofibromatosis 1 | 0.078 | |
Hnrnpa3 | heterogeneous nuclear ribonucleoprotein A3 | 0.077 | |
Nos1 | nitric oxide synthase 1, neuronal | 0.076 | |
Csf2 | colony stimulating factor 2 (granulocyte-macrophage) | 0.074 | |
Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.072 | |
Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.070 | |
Tbx1 | T-box 1 | 0.066 | |
Foxc2 | forkhead box C2 | 0.065 | |
Prkce | protein kinase C, epsilon | 0.064 | |
Dsg4 | desmoglein 4 | 0.064 | |
Trp53 | transformation related protein 53 | 0.064 | |
Tnfrsf11a | tumor necrosis factor receptor superfamily, member 11a | 0.063 | |
Zeb1 | zinc finger E-box binding homeobox 1 | 0.062 | |
Srsf6 | serine/arginine-rich splicing factor 6 | 0.062 | |
Apoe | apolipoprotein E | 0.061 | |
Bcl2 | B-cell leukemia/lymphoma 2 | 0.060 | |
Zfp36 | zinc finger protein 36 | 0.059 | |
Hnrnpd | heterogeneous nuclear ribonucleoprotein D | 0.059 | |
Fgf8 | fibroblast growth factor 8 | 0.058 | |
Nodal | nodal | 0.058 | |
Pgr | progesterone receptor | 0.057 | |
Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.055 | |
Fshr | follicle stimulating hormone receptor | 0.055 | |
Prrx1 | paired related homeobox 1 | 0.055 | |
Gata4 | GATA binding protein 4 | 0.054 | |
Lep | leptin | 0.054 | |
Eng | endoglin | 0.052 | |
Chrd | chordin | 0.052 | |
Pard3 | par-3 (partitioning defective 3) homolog (C. elegans) | 0.051 | |
Fmn1 | formin 1 | 0.048 | |
Kit | kit oncogene | 0.048 | |
Set | SET nuclear oncogene | 0.048 | |
Nucks1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.044 | |
Rara | retinoic acid receptor, alpha | 0.044 | |
Atf3 | activating transcription factor 3 | 0.044 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
RARA | retinoic acid receptor, alpha | 0.992 | |
RXRA | retinoid X receptor, alpha | 0.938 | |
PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.686 | |
NCOA1 | nuclear receptor coactivator 1 | 0.626 | |
MED25 | mediator complex subunit 25 | 0.335 | |
PLAU | plasminogen activator, urokinase | 0.270 | |
HNF4A | hepatocyte nuclear factor 4, alpha | 0.214 | |
JUN | jun proto-oncogene | 0.204 | |
NCOR2 | nuclear receptor corepressor 2 | 0.139 | |
NCOA3 | nuclear receptor coactivator 3 | 0.072 | |
RANBP3 | RAN binding protein 3 | 0.043 | |
FAM46A | family with sequence similarity 46, member A | 0.033 | |
PRKG1 | protein kinase, cGMP-dependent, type I | 0.032 | |
SOCS3 | suppressor of cytokine signaling 3 | 0.025 | |
VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.018 | |
APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.017 | |
IER3 | immediate early response 3 | 0.017 | |
CSTA | cystatin A (stefin A) | 0.016 | |
RGS2 | regulator of G-protein signaling 2, 24kDa | 0.015 | |
FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.015 | |
ESR1 | estrogen receptor 1 | 0.014 | |
SPOP | speckle-type POZ protein | 0.013 | |
ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | 0.012 | |
PRDX4 | peroxiredoxin 4 | 0.012 | |
TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.011 | |
ACVR1 | activin A receptor, type I | 0.011 |