The network for 'maternal placenta development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

maternal placenta development

Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.

Name Description Probability Func Analog Organism
Tgfbr2 transforming growth factor, beta receptor II 0.998
Pten phosphatase and tensin homolog 0.989
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.977
Bmp4 bone morphogenetic protein 4 0.954
Fgfr2 fibroblast growth factor receptor 2 0.879
Foxc1 forkhead box C1 0.868
Csf1 colony stimulating factor 1 (macrophage) 0.830
Esr1 estrogen receptor 1 (alpha) 0.790
Ctnnb1 catenin (cadherin associated protein), beta 1 0.752
Nos3 nitric oxide synthase 3, endothelial cell 0.743
Vegfa vascular endothelial growth factor A 0.740
Apc adenomatosis polyposis coli 0.701
Bmp7 bone morphogenetic protein 7 0.694
Mapk8 mitogen-activated protein kinase 8 0.607
Fgfr3 fibroblast growth factor receptor 3 0.595
Smad4 MAD homolog 4 (Drosophila) 0.521
Foxh1 forkhead box H1 0.492
Bmpr1a bone morphogenetic protein receptor, type 1A 0.486
Sox9 SRY-box containing gene 9 0.464
Smad3 MAD homolog 3 (Drosophila) 0.456
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.447
Egr1 early growth response 1 0.428
Col1a1 collagen, type I, alpha 1 0.412
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.354
Pparg peroxisome proliferator activated receptor gamma 0.332
Ptgs2 prostaglandin-endoperoxide synthase 2 0.330
Tgfbr1 transforming growth factor, beta receptor I 0.318
Runx2 runt related transcription factor 2 0.286
Bmp2 bone morphogenetic protein 2 0.280
Fos FBJ osteosarcoma oncogene 0.265
Tgfb2 transforming growth factor, beta 2 0.260
Esr2 estrogen receptor 2 (beta) 0.253
Rarg retinoic acid receptor, gamma 0.229
Meox2 mesenchyme homeobox 2 0.216
Pitx2 paired-like homeodomain transcription factor 2 0.185
Lepr leptin receptor 0.180
Ptch1 patched homolog 1 0.177
Dicer1 Dicer1, Dcr-1 homolog (Drosophila) 0.162
Fgfr1 fibroblast growth factor receptor 1 0.154
Gsk3b glycogen synthase kinase 3 beta 0.145
Smo smoothened homolog (Drosophila) 0.141
Vhl von Hippel-Lindau tumor suppressor 0.138
Msx2 homeobox, msh-like 2 0.135
Ghr growth hormone receptor 0.134
Nos2 nitric oxide synthase 2, inducible 0.131
Ldb3 LIM domain binding 3 0.120
Acvr1 activin A receptor, type 1 0.118
Notch2 Notch gene homolog 2 (Drosophila) 0.116
Cav1 caveolin 1, caveolae protein 0.116
Il2rg interleukin 2 receptor, gamma chain 0.115
Pax2 paired box gene 2 0.115
Shh sonic hedgehog 0.112
Ctsd cathepsin D 0.112
Hnrnpk heterogeneous nuclear ribonucleoprotein K 0.110
Ece1 endothelin converting enzyme 1 0.108
Rarb retinoic acid receptor, beta 0.094
Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 0.093
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.093
Bmper BMP-binding endothelial regulator 0.093
Egfr epidermal growth factor receptor 0.089
Nr2f2 nuclear receptor subfamily 2, group F, member 2 0.085
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.084
Rxra retinoid X receptor alpha 0.082
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.080
Fus fusion, derived from t(12;16) malignant liposarcoma (human) 0.079
Nf1 neurofibromatosis 1 0.078
Hnrnpa3 heterogeneous nuclear ribonucleoprotein A3 0.077
Nos1 nitric oxide synthase 1, neuronal 0.076
Csf2 colony stimulating factor 2 (granulocyte-macrophage) 0.074
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.072
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.070
Tbx1 T-box 1 0.066
Foxc2 forkhead box C2 0.065
Prkce protein kinase C, epsilon 0.064
Dsg4 desmoglein 4 0.064
Trp53 transformation related protein 53 0.064
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.063
Zeb1 zinc finger E-box binding homeobox 1 0.062
Srsf6 serine/arginine-rich splicing factor 6 0.062
Apoe apolipoprotein E 0.061
Bcl2 B-cell leukemia/lymphoma 2 0.060
Zfp36 zinc finger protein 36 0.059
Hnrnpd heterogeneous nuclear ribonucleoprotein D 0.059
Fgf8 fibroblast growth factor 8 0.058
Nodal nodal 0.058
Pgr progesterone receptor 0.057
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.055
Fshr follicle stimulating hormone receptor 0.055
Prrx1 paired related homeobox 1 0.055
Gata4 GATA binding protein 4 0.054
Lep leptin 0.054
Eng endoglin 0.052
Chrd chordin 0.052
Pard3 par-3 (partitioning defective 3) homolog (C. elegans) 0.051
Fmn1 formin 1 0.048
Kit kit oncogene 0.048
Set SET nuclear oncogene 0.048
Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.044
Rara retinoic acid receptor, alpha 0.044
Atf3 activating transcription factor 3 0.044
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
RARA retinoic acid receptor, alpha 0.992
RXRA retinoid X receptor, alpha 0.938
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.686
NCOA1 nuclear receptor coactivator 1 0.626
MED25 mediator complex subunit 25 0.335
PLAU plasminogen activator, urokinase 0.270
HNF4A hepatocyte nuclear factor 4, alpha 0.214
JUN jun proto-oncogene 0.204
NCOR2 nuclear receptor corepressor 2 0.139
NCOA3 nuclear receptor coactivator 3 0.072
RANBP3 RAN binding protein 3 0.043
FAM46A family with sequence similarity 46, member A 0.033
PRKG1 protein kinase, cGMP-dependent, type I 0.032
SOCS3 suppressor of cytokine signaling 3 0.025
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.018
APLP2 amyloid beta (A4) precursor-like protein 2 0.017
IER3 immediate early response 3 0.017
CSTA cystatin A (stefin A) 0.016
RGS2 regulator of G-protein signaling 2, 24kDa 0.015
FOS FBJ murine osteosarcoma viral oncogene homolog 0.015
ESR1 estrogen receptor 1 0.014
SPOP speckle-type POZ protein 0.013
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 0.012
PRDX4 peroxiredoxin 4 0.012
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.011
ACVR1 activin A receptor, type I 0.011
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Rattus norvegicus
Name Description Probability Func Analog Organism
Nefl neurofilament, light polypeptide 0.023
Nefm neurofilament, medium polypeptide 0.020
Anxa5 annexin A5 0.015
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism