IMP

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Homo sapiens

33 genes annotated in human

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lysosomal transport

GO:0007041

The directed movement of substances into, out of or within a lysosome.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "lysosomal transport"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "lysosomal transport" (in gray)

Name	Description	Probability	Func Analog Organism
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.965	Human
AKTIP	AKT interacting protein	0.947
STAMBP	STAM binding protein	0.934
GGA2	golgi-associated, gamma adaptin ear containing, ARF binding protein 2	0.846
GGA1	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	0.660
MTM1	myotubularin 1	0.657
MTMR12	myotubularin related protein 12	0.640	Human
VTI1B	vesicle transport through interaction with t-SNAREs homolog 1B (yeast)	0.635
VPS41	vacuolar protein sorting 41 homolog (S. cerevisiae)	0.603
SMAD4	SMAD family member 4	0.565
SYNRG	synergin, gamma	0.559
VPS33B	vacuolar protein sorting 33 homolog B (yeast)	0.533
ANK1	ankyrin 1, erythrocytic	0.477	Human
ARHGAP1	Rho GTPase activating protein 1	0.433
GBA	glucosidase, beta, acid	0.413
RABEP1	rabaptin, RAB GTPase binding effector protein 1	0.405
EPS15	epidermal growth factor receptor pathway substrate 15	0.399
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.396
GGA3	golgi-associated, gamma adaptin ear containing, ARF binding protein 3	0.329
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.316	Human
STAM2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	0.266
ARMCX3	armadillo repeat containing, X-linked 3	0.257
ZFYVE9	zinc finger, FYVE domain containing 9	0.250	Human
CLASP1	cytoplasmic linker associated protein 1	0.248
ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A	0.243
LAMP2	lysosomal-associated membrane protein 2	0.232	Human
SPTB	spectrin, beta, erythrocytic	0.229	Human
SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)	0.222
GPRASP1	G protein-coupled receptor associated sorting protein 1	0.215
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.202
ATP6V1C1	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1	0.199
HOOK2	hook homolog 2 (Drosophila)	0.194
IGF2R	insulin-like growth factor 2 receptor	0.184
ANKRD27	ankyrin repeat domain 27 (VPS9 domain)	0.178
GNS	glucosamine (N-acetyl)-6-sulfatase	0.173
RAB5A	RAB5A, member RAS oncogene family	0.170
ATP6V1B2	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2	0.167
SNX3	sorting nexin 3	0.141
RNF11	ring finger protein 11	0.133
HOOK3	hook homolog 3 (Drosophila)	0.128
SPG21	spastic paraplegia 21 (autosomal recessive, Mast syndrome)	0.118
VAMP3	vesicle-associated membrane protein 3 (cellubrevin)	0.115
CXXC5	CXXC finger protein 5	0.113
HEXDC	hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing	0.108
EEA1	early endosome antigen 1	0.104
FBXL15	F-box and leucine-rich repeat protein 15	0.103
CHMP2B	chromatin modifying protein 2B	0.099
EXOC5	exocyst complex component 5	0.097
RAB14	RAB14, member RAS oncogene family	0.095
SH3KBP1	SH3-domain kinase binding protein 1	0.094
ANKRD13A	ankyrin repeat domain 13A	0.092
SNX9	sorting nexin 9	0.087
STX7	syntaxin 7	0.085	Rat
TOM1	target of myb1 (chicken)	0.080
MTMR6	myotubularin related protein 6	0.075	Human
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.074
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.071	Human
SKIL	SKI-like oncogene	0.070
RANBP9	RAN binding protein 9	0.067
ASAH1	N-acylsphingosine amidohydrolase (acid ceramidase) 1	0.065
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.064
PTPRN	protein tyrosine phosphatase, receptor type, N	0.062
ROCK1	Rho-associated, coiled-coil containing protein kinase 1	0.061
CAPRIN2	caprin family member 2	0.059
JUP	junction plakoglobin	0.057
DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	0.056
VAMP8	vesicle-associated membrane protein 8 (endobrevin)	0.056
USP15	ubiquitin specific peptidase 15	0.055
LRP3	low density lipoprotein receptor-related protein 3	0.054
DISC1	disrupted in schizophrenia 1	0.052
EHD1	EH-domain containing 1	0.051
UBE2W	ubiquitin-conjugating enzyme E2W (putative)	0.050
EXOC8	exocyst complex component 8	0.049
ANTXR2	anthrax toxin receptor 2	0.049
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.047
SNAP23	synaptosomal-associated protein, 23kDa	0.046
GPRASP2	G protein-coupled receptor associated sorting protein 2	0.046
WDR47	WD repeat domain 47	0.045
GAK	cyclin G associated kinase	0.045
EXOC1	exocyst complex component 1	0.043
CHD6	chromodomain helicase DNA binding protein 6	0.043
SGK3	serum/glucocorticoid regulated kinase family, member 3	0.042
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.040
ZNF654	zinc finger protein 654	0.040
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.040
VPS26A	vacuolar protein sorting 26 homolog A (S. pombe)	0.040
PAPOLA	poly(A) polymerase alpha	0.040
SMAD9	SMAD family member 9	0.040
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.038
RHAG	Rh-associated glycoprotein	0.038
TCEAL4	transcription elongation factor A (SII)-like 4	0.038
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.038	Human
RNF13	ring finger protein 13	0.037
SLC9A6	solute carrier family 9 (sodium/hydrogen exchanger), member 6	0.037
KIAA1033	KIAA1033	0.037
TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	0.037
CYB5R4	cytochrome b5 reductase 4	0.036
NCSTN	nicastrin	0.036
MED15	mediator complex subunit 15	0.036
CHIC2	cysteine-rich hydrophobic domain 2	0.036
TNIK	TRAF2 and NCK interacting kinase	0.036
CREB3	cAMP responsive element binding protein 3	0.035
LRRK2	leucine-rich repeat kinase 2	0.035
MTMR9	myotubularin related protein 9	0.034	Human
BLOC1S2	biogenesis of lysosomal organelles complex-1, subunit 2	0.034
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.034	Human
LDLR	low density lipoprotein receptor	0.033
KPNA4	karyopherin alpha 4 (importin alpha 3)	0.033
NBR1	neighbor of BRCA1 gene 1	0.033
TGFBR1	transforming growth factor, beta receptor 1	0.033
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.032
RTN1	reticulon 1	0.032
GOLGA7	golgin A7	0.032
DTNBP1	dystrobrevin binding protein 1	0.031
ABTB1	ankyrin repeat and BTB (POZ) domain containing 1	0.031
YTHDF3	YTH domain family, member 3	0.031
NRBF2	nuclear receptor binding factor 2	0.031
ZEB2	zinc finger E-box binding homeobox 2	0.031
MAP3K2	mitogen-activated protein kinase kinase kinase 2	0.030
RAP1B	RAP1B, member of RAS oncogene family	0.030
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.030
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.030
RDX	radixin	0.030
BECN1	beclin 1, autophagy related	0.029
HOOK1	hook homolog 1 (Drosophila)	0.028
STXBP3	syntaxin binding protein 3	0.028
ZRANB1	zinc finger, RAN-binding domain containing 1	0.028
AGFG1	ArfGAP with FG repeats 1	0.028
HIPK3	homeodomain interacting protein kinase 3	0.028
ROD1	ROD1 regulator of differentiation 1 (S. pombe)	0.027
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.027
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.026
ARFIP1	ADP-ribosylation factor interacting protein 1	0.026
ATXN3	ataxin 3	0.026
MOSPD1	motile sperm domain containing 1	0.026
ABLIM1	actin binding LIM protein 1	0.026
GPBP1L1	GC-rich promoter binding protein 1-like 1	0.026
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.025
NF2	neurofibromin 2 (merlin)	0.025
ZFYVE26	zinc finger, FYVE domain containing 26	0.025
OSTM1	osteopetrosis associated transmembrane protein 1	0.025
DCAF7	DDB1 and CUL4 associated factor 7	0.025
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	0.024
MON2	MON2 homolog (S. cerevisiae)	0.024
TAX1BP1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.024
KLF5	Kruppel-like factor 5 (intestinal)	0.024
ITM2B	integral membrane protein 2B	0.024
TRAF3IP1	TNF receptor-associated factor 3 interacting protein 1	0.024
ABCF3	ATP-binding cassette, sub-family F (GCN20), member 3	0.024
APPBP2	amyloid beta precursor protein (cytoplasmic tail) binding protein 2	0.023
MARCH5	membrane-associated ring finger (C3HC4) 5	0.023
MBIP	MAP3K12 binding inhibitory protein 1	0.023
MUL1	mitochondrial E3 ubiquitin protein ligase 1	0.022
DOCK9	dedicator of cytokinesis 9	0.022
CLIP1	CAP-GLY domain containing linker protein 1	0.022
UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	0.022
POU5F1	POU class 5 homeobox 1	0.022
DOCK8	dedicator of cytokinesis 8	0.021
CLCN3	chloride channel 3	0.021
EZR	ezrin	0.021
KIF5B	kinesin family member 5B	0.021
GATAD2B	GATA zinc finger domain containing 2B	0.021
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.021
MTMR10	myotubularin related protein 10	0.021	Human
REEP6	receptor accessory protein 6	0.020
VPS24	vacuolar protein sorting 24 homolog (S. cerevisiae)	0.020
MICALL1	MICAL-like 1	0.020
RNF146	ring finger protein 146	0.020
CREBL2	cAMP responsive element binding protein-like 2	0.020
ADAM10	ADAM metallopeptidase domain 10	0.020
TRAF4	TNF receptor-associated factor 4	0.020
RAB9A	RAB9A, member RAS oncogene family	0.020
MAPK1	mitogen-activated protein kinase 1	0.020
CTSA	cathepsin A	0.020
SGMS1	sphingomyelin synthase 1	0.019
VPS37A	vacuolar protein sorting 37 homolog A (S. cerevisiae)	0.019
SMAD1	SMAD family member 1	0.019
NECAP1	NECAP endocytosis associated 1	0.019
ACAP2	ArfGAP with coiled-coil, ankyrin repeat and PH domains 2	0.019
ZFYVE16	zinc finger, FYVE domain containing 16	0.019
HEXB	hexosaminidase B (beta polypeptide)	0.019
MTMR4	myotubularin related protein 4	0.018	Human
LEPROT	leptin receptor overlapping transcript	0.018
TMBIM6	transmembrane BAX inhibitor motif containing 6	0.018
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.018
CLINT1	clathrin interactor 1	0.018
RNF168	ring finger protein 168	0.018
TTN	titin	0.018
RAB10	RAB10, member RAS oncogene family	0.018
PEX19	peroxisomal biogenesis factor 19	0.018
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.018	Human
CKAP2L	cytoskeleton associated protein 2-like	0.018
ATP6V0E1	ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1	0.018
HGS	hepatocyte growth factor-regulated tyrosine kinase substrate	0.018
PPM1A	protein phosphatase, Mg2+/Mn2+ dependent, 1A	0.018
SCARB2	scavenger receptor class B, member 2	0.018
AMBRA1	autophagy/beclin-1 regulator 1	0.017
MPP5	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	0.017
WDFY3	WD repeat and FYVE domain containing 3	0.017
STAM	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	0.017	Worm
SNX6	sorting nexin 6	0.017
EIF1B	eukaryotic translation initiation factor 1B	0.017
PPIL4	peptidylprolyl isomerase (cyclophilin)-like 4	0.017
CPD	carboxypeptidase D	0.017
TRIP12	thyroid hormone receptor interactor 12	0.017
SLAIN2	SLAIN motif family, member 2	0.017
MOSPD2	motile sperm domain containing 2	0.017
SORT1	sortilin 1	0.017
RP2	retinitis pigmentosa 2 (X-linked recessive)	0.017
DST	dystonin	0.017
UEVLD	UEV and lactate/malate dehyrogenase domains	0.017
PDCD6IP	programmed cell death 6 interacting protein	0.016
THRAP3	thyroid hormone receptor associated protein 3	0.016
MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3	0.016
CSNK1D	casein kinase 1, delta	0.016
SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)	0.016
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	0.016
WNT3A	wingless-type MMTV integration site family, member 3A	0.016
VAMP4	vesicle-associated membrane protein 4	0.016
BEND7	BEN domain containing 7	0.016
EFR3A	EFR3 homolog A (S. cerevisiae)	0.016
DYNC1I2	dynein, cytoplasmic 1, intermediate chain 2	0.016
YAP1	Yes-associated protein 1	0.016
FZD5	frizzled homolog 5 (Drosophila)	0.016
DYNLT3	dynein, light chain, Tctex-type 3	0.015
CNOT1	CCR4-NOT transcription complex, subunit 1	0.015
TMEM30A	transmembrane protein 30A	0.015
VPS4B	vacuolar protein sorting 4 homolog B (S. cerevisiae)	0.015
FOXD3	forkhead box D3	0.015
ZFAND5	zinc finger, AN1-type domain 5	0.015
SYT11	synaptotagmin XI	0.015
PSAP	prosaposin	0.015
STX12	syntaxin 12	0.014
KIAA0196	KIAA0196	0.014
CPNE3	copine III	0.014
API5	apoptosis inhibitor 5	0.014
ATP6V1D	ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D	0.014
VPS33A	vacuolar protein sorting 33 homolog A (S. cerevisiae)	0.014	Fly
VASP	vasodilator-stimulated phosphoprotein	0.014
NSF	N-ethylmaleimide-sensitive factor	0.014
UBQLN2	ubiquilin 2	0.014
TMEM188	transmembrane protein 188	0.014
ARFGEF2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)	0.014
SRI	sorcin	0.014
ACVR1	activin A receptor, type I	0.014
RAB21	RAB21, member RAS oncogene family	0.014
PPP4R2	protein phosphatase 4, regulatory subunit 2	0.014
ARMCX6	armadillo repeat containing, X-linked 6	0.014	Human
RAB6A	RAB6A, member RAS oncogene family	0.014
DTX1	deltex homolog 1 (Drosophila)	0.014
MKL2	MKL/myocardin-like 2	0.013
KLF2	Kruppel-like factor 2 (lung)	0.013
ERBB2IP	erbb2 interacting protein	0.013
PPM1D	protein phosphatase, Mg2+/Mn2+ dependent, 1D	0.013
KCTD9	potassium channel tetramerisation domain containing 9	0.013
IGF1R	insulin-like growth factor 1 receptor	0.013
RAP2C	RAP2C, member of RAS oncogene family	0.013
SOX7	SRY (sex determining region Y)-box 7	0.013
DLG1	discs, large homolog 1 (Drosophila)	0.013
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.013
MEAF6	MYST/Esa1-associated factor 6	0.013
KIAA0232	KIAA0232	0.013
PRPSAP1	phosphoribosyl pyrophosphate synthetase-associated protein 1	0.013
NCOA4	nuclear receptor coactivator 4	0.013
MLLT3	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3	0.013
ARL8B	ADP-ribosylation factor-like 8B	0.013	Worm
DNM2	dynamin 2	0.013
RAB22A	RAB22A, member RAS oncogene family	0.013
SIK3	SIK family kinase 3	0.013
CREG1	cellular repressor of E1A-stimulated genes 1	0.013
CAB39	calcium binding protein 39	0.013
CHM	choroideremia (Rab escort protein 1)	0.013
SNAPIN	SNAP-associated protein	0.012
GMFB	glia maturation factor, beta	0.012
MFSD1	major facilitator superfamily domain containing 1	0.012
DYNC1LI2	dynein, cytoplasmic 1, light intermediate chain 2	0.012
KLHL2	kelch-like 2, Mayven (Drosophila)	0.012
KCTD20	potassium channel tetramerisation domain containing 20	0.012
KIDINS220	kinase D-interacting substrate, 220kDa	0.012
BCL2	B-cell CLL/lymphoma 2	0.012
GTF3C1	general transcription factor IIIC, polypeptide 1, alpha 220kDa	0.012
WASH1	WAS protein family homolog 1	0.012
SH3BP4	SH3-domain binding protein 4	0.012
SBF2	SET binding factor 2	0.012
EVC2	Ellis van Creveld syndrome 2	0.012
ING2	inhibitor of growth family, member 2	0.012
CAST	calpastatin	0.012
SORL1	sortilin-related receptor, L(DLR class) A repeats containing	0.012
PIK3C3	phosphoinositide-3-kinase, class 3	0.012
RBM18	RNA binding motif protein 18	0.012
CALCOCO2	calcium binding and coiled-coil domain 2	0.012
CCDC127	coiled-coil domain containing 127	0.012
UVRAG	UV radiation resistance associated gene	0.012
PLCB1	phospholipase C, beta 1 (phosphoinositide-specific)	0.012
RRM2B	ribonucleotide reductase M2 B (TP53 inducible)	0.012
PNPLA3	patatin-like phospholipase domain containing 3	0.012
OSBP2	oxysterol binding protein 2	0.012
CCDC28A	coiled-coil domain containing 28A	0.012
PARP4	poly (ADP-ribose) polymerase family, member 4	0.012
DEPDC1	DEP domain containing 1	0.012
USP32	ubiquitin specific peptidase 32	0.012
ARF1	ADP-ribosylation factor 1	0.012
PLEKHO1	pleckstrin homology domain containing, family O member 1	0.012
PAPSS1	3'-phosphoadenosine 5'-phosphosulfate synthase 1	0.012
PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	0.012
NEK2	NIMA (never in mitosis gene a)-related kinase 2	0.012
SF3B3	splicing factor 3b, subunit 3, 130kDa	0.011
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.011
LEMD3	LEM domain containing 3	0.011
USP38	ubiquitin specific peptidase 38	0.011
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.011
CCDC33	coiled-coil domain containing 33	0.011
SYNJ1	synaptojanin 1	0.011
RHOG	ras homolog gene family, member G (rho G)	0.011
RTN3	reticulon 3	0.011
TSG101	tumor susceptibility gene 101	0.011
PRRC1	proline-rich coiled-coil 1	0.011
PPP1R12C	protein phosphatase 1, regulatory (inhibitor) subunit 12C	0.011
ADD2	adducin 2 (beta)	0.011
SNX2	sorting nexin 2	0.011
TIAM1	T-cell lymphoma invasion and metastasis 1	0.011
MAP2K4	mitogen-activated protein kinase kinase 4	0.011
SNX33	sorting nexin 33	0.011
ZMYND11	zinc finger, MYND-type containing 11	0.011
FIG4	FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)	0.011
SPPL2A	signal peptide peptidase-like 2A	0.011
EAF1	ELL associated factor 1	0.011
FBXL5	F-box and leucine-rich repeat protein 5	0.011
LIG4	ligase IV, DNA, ATP-dependent	0.011
RHOT1	ras homolog gene family, member T1	0.011
ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5	0.011
PHLPP2	PH domain and leucine rich repeat protein phosphatase 2	0.011
SPOPL	speckle-type POZ protein-like	0.011
PACSIN2	protein kinase C and casein kinase substrate in neurons 2	0.011
DNAJC7	DnaJ (Hsp40) homolog, subfamily C, member 7	0.011
POLH	polymerase (DNA directed), eta	0.011
UBE2Q2	ubiquitin-conjugating enzyme E2Q family member 2	0.010
DRAM2	DNA-damage regulated autophagy modulator 2	0.010
CTBP2	C-terminal binding protein 2	0.010
DAPK1	death-associated protein kinase 1	0.010
FYTTD1	forty-two-three domain containing 1	0.010
ERC1	ELKS/RAB6-interacting/CAST family member 1	0.010
ATP2C1	ATPase, Ca++ transporting, type 2C, member 1	0.010
PHKB	phosphorylase kinase, beta	0.010