IMP

Process View

Homo sapiens

1 genes annotated in human

Multi-species View

regulation of antimicrobial humoral response

GO:0002759

Any process that modulates the frequency, rate, or extent of an antimicrobial humoral response.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of antimicrobial humoral response"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of antimicrobial humoral response" (in gray)

Name	Description	Probability	Func Analog Organism
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	1.000
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.994	Fly
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.985	Fly
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.983	Fly
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.942
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.937	Fly
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.921	Fly
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.911	Fly
BCL3	B-cell CLL/lymphoma 3	0.804	Fly
TNIP2	TNFAIP3 interacting protein 2	0.658
SOX10	SRY (sex determining region Y)-box 10	0.649
SNTA1	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)	0.602
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.591	Fly
CHUK	conserved helix-loop-helix ubiquitous kinase	0.574	Fly
JUNB	jun B proto-oncogene	0.467	Fly
CRADD	CASP2 and RIPK1 domain containing adaptor with death domain	0.432
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.386
IL4R	interleukin 4 receptor	0.378
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.298
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.293	Fly
CASP4	caspase 4, apoptosis-related cysteine peptidase	0.267	Fly
RARA	retinoic acid receptor, alpha	0.224
ATF3	activating transcription factor 3	0.220
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.187
NLRC4	NLR family, CARD domain containing 4	0.173
STAP2	signal transducing adaptor family member 2	0.151
RXRA	retinoid X receptor, alpha	0.139
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.128
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.124
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.120
CPNE6	copine VI (neuronal)	0.109
TLR2	toll-like receptor 2	0.106
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.074
DUSP1	dual specificity phosphatase 1	0.070
RIPK2	receptor-interacting serine-threonine kinase 2	0.068
INSR	insulin receptor	0.067
JUN	jun proto-oncogene	0.067	Fly
IL2RB	interleukin 2 receptor, beta	0.064
IER2	immediate early response 2	0.060
PKN1	protein kinase N1	0.059
NCOA1	nuclear receptor coactivator 1	0.057
JAK1	Janus kinase 1	0.056
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.055
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.054
TLR4	toll-like receptor 4	0.053
ASH2L	ash2 (absent, small, or homeotic)-like (Drosophila)	0.051
C16orf53	chromosome 16 open reading frame 53	0.050
MAPK8	mitogen-activated protein kinase 8	0.048
MAVS	mitochondrial antiviral signaling protein	0.046
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.043
RAI1	retinoic acid induced 1	0.041
ITGB1BP1	integrin beta 1 binding protein 1	0.041
CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha	0.041
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.041
NMI	N-myc (and STAT) interactor	0.040
TP53BP1	tumor protein p53 binding protein 1	0.039
EVL	Enah/Vasp-like	0.038
SOCS3	suppressor of cytokine signaling 3	0.036
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.036
RBBP5	retinoblastoma binding protein 5	0.035
TMEM173	transmembrane protein 173	0.035
JUND	jun D proto-oncogene	0.035	Fly
EPB49	erythrocyte membrane protein band 4.9 (dematin)	0.034
TBX5	T-box 5	0.034
PPP1R15A	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.034
ELF4	E74-like factor 4 (ets domain transcription factor)	0.034
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.034
FKBP5	FK506 binding protein 5	0.033
SOX1	SRY (sex determining region Y)-box 1	0.032
IRAK2	interleukin-1 receptor-associated kinase 2	0.032
SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1	0.031
TCF4	transcription factor 4	0.031
TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	0.031
CSNK1A1	casein kinase 1, alpha 1	0.031
BIRC3	baculoviral IAP repeat containing 3	0.030
BATF2	basic leucine zipper transcription factor, ATF-like 2	0.030
PAX3	paired box 3	0.029
EGR1	early growth response 1	0.029
PRUNE	prune homolog (Drosophila)	0.029
ATXN3	ataxin 3	0.029
IL4	interleukin 4	0.028
IRF1	interferon regulatory factor 1	0.028
KDM6B	lysine (K)-specific demethylase 6B	0.028
MEN1	multiple endocrine neoplasia I	0.028
EP300	E1A binding protein p300	0.028
PYCARD	PYD and CARD domain containing	0.027
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.027
DUSP9	dual specificity phosphatase 9	0.027
ZC3H12A	zinc finger CCCH-type containing 12A	0.027
CARD16	caspase recruitment domain family, member 16	0.026
FLOT1	flotillin 1	0.026
BTRC	beta-transducin repeat containing	0.025
BEND5	BEN domain containing 5	0.025
TLR1	toll-like receptor 1	0.024
BTBD2	BTB (POZ) domain containing 2	0.024
MVP	major vault protein	0.024
SOX21	SRY (sex determining region Y)-box 21	0.024
USP20	ubiquitin specific peptidase 20	0.024
NCOA3	nuclear receptor coactivator 3	0.024
UBXN7	UBX domain protein 7	0.024
SFRP5	secreted frizzled-related protein 5	0.023
SQRDL	sulfide quinone reductase-like (yeast)	0.022
NCOA6	nuclear receptor coactivator 6	0.022
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.022
UROD	uroporphyrinogen decarboxylase	0.022
MAPK15	mitogen-activated protein kinase 15	0.022
POLR3D	polymerase (RNA) III (DNA directed) polypeptide D, 44kDa	0.022
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.022
TRIM33	tripartite motif containing 33	0.022
GATA4	GATA binding protein 4	0.022	Fly
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.021
POU3F2	POU class 3 homeobox 2	0.021	Fly
IL18	interleukin 18 (interferon-gamma-inducing factor)	0.021
KLF13	Kruppel-like factor 13	0.021
CEBPD	CCAAT/enhancer binding protein (C/EBP), delta	0.021
GBP2	guanylate binding protein 2, interferon-inducible	0.020
N4BP2L2	NEDD4 binding protein 2-like 2	0.020
MYL12A	myosin, light chain 12A, regulatory, non-sarcomeric	0.019
FOSL1	FOS-like antigen 1	0.019
RBM25	RNA binding motif protein 25	0.019
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.019
TRAF3	TNF receptor-associated factor 3	0.019
MAPK1	mitogen-activated protein kinase 1	0.019
RBBP4	retinoblastoma binding protein 4	0.019
SPTBN1	spectrin, beta, non-erythrocytic 1	0.019
IL2RG	interleukin 2 receptor, gamma	0.018
GATA5	GATA binding protein 5	0.018	Fly
PPM1D	protein phosphatase, Mg2+/Mn2+ dependent, 1D	0.018
ZNF282	zinc finger protein 282	0.018
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.018
DOCK8	dedicator of cytokinesis 8	0.018
HAND2	heart and neural crest derivatives expressed 2	0.018
AES	amino-terminal enhancer of split	0.018
FANCC	Fanconi anemia, complementation group C	0.018
DDIT3	DNA-damage-inducible transcript 3	0.017
RAX	retina and anterior neural fold homeobox	0.017
POU3F3	POU class 3 homeobox 3	0.017	Fly
CDX2	caudal type homeobox 2	0.017	Fly
DDX24	DEAD (Asp-Glu-Ala-Asp) box polypeptide 24	0.017
ATAD2B	ATPase family, AAA domain containing 2B	0.017
RXRB	retinoid X receptor, beta	0.017
CCNL1	cyclin L1	0.017
POU3F4	POU class 3 homeobox 4	0.017	Fly
NLRC5	NLR family, CARD domain containing 5	0.017
ZBTB8A	zinc finger and BTB domain containing 8A	0.017
UBE4B	ubiquitination factor E4B (UFD2 homolog, yeast)	0.017
ALX4	ALX homeobox 4	0.016
NOTCH1	notch 1	0.016
MTHFD1L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like	0.016
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.016
IFI16	interferon, gamma-inducible protein 16	0.016
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.016
TRAF2	TNF receptor-associated factor 2	0.016
ANKRD36B	ankyrin repeat domain 36B	0.016
FAS	Fas (TNF receptor superfamily, member 6)	0.016
F2	coagulation factor II (thrombin)	0.016
NLK	nemo-like kinase	0.016
TAF5L	TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa	0.016
MARK2	MAP/microtubule affinity-regulating kinase 2	0.016
GRB10	growth factor receptor-bound protein 10	0.016
KRT15	keratin 15	0.016
MAP2K6	mitogen-activated protein kinase kinase 6	0.016
STAT5B	signal transducer and activator of transcription 5B	0.016	Fly
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.016
TYK2	tyrosine kinase 2	0.016
TNFSF13B	tumor necrosis factor (ligand) superfamily, member 13b	0.015
ICAM1	intercellular adhesion molecule 1	0.015
MAP2K3	mitogen-activated protein kinase kinase 3	0.015
JAK2	Janus kinase 2	0.015
GCFC1	GC-rich sequence DNA-binding factor 1	0.015
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.015
TP73	tumor protein p73	0.015
MKNK1	MAP kinase interacting serine/threonine kinase 1	0.015
DUSP8	dual specificity phosphatase 8	0.015
H1FX	H1 histone family, member X	0.015
TRIM14	tripartite motif containing 14	0.015
ASCL1	achaete-scute complex homolog 1 (Drosophila)	0.015	Fly
MTA2	metastasis associated 1 family, member 2	0.015
POU3F1	POU class 3 homeobox 1	0.015	Fly
MED16	mediator complex subunit 16	0.015
OBSL1	obscurin-like 1	0.015
CARD6	caspase recruitment domain family, member 6	0.015
ALX3	ALX homeobox 3	0.014
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.014
METTL21D	methyltransferase like 21D	0.014
SLTM	SAFB-like, transcription modulator	0.014
SIRT6	sirtuin 6	0.014
HNRNPL	heterogeneous nuclear ribonucleoprotein L	0.014
PDX1	pancreatic and duodenal homeobox 1	0.014
NOVA2	neuro-oncological ventral antigen 2	0.014
SOCS1	suppressor of cytokine signaling 1	0.014
MED19	mediator complex subunit 19	0.014
MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	0.014
TNIP1	TNFAIP3 interacting protein 1	0.014
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.014
FOXB1	forkhead box B1	0.014
BHLHE23	basic helix-loop-helix family, member e23	0.014
GORAB	golgin, RAB6-interacting	0.014
FUT6	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)	0.014
GSK3B	glycogen synthase kinase 3 beta	0.014
CUL7	cullin 7	0.014
MDN1	MDN1, midasin homolog (yeast)	0.014
IRF2BP1	interferon regulatory factor 2 binding protein 1	0.013
NOD2	nucleotide-binding oligomerization domain containing 2	0.013
ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)	0.013
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.013
LHX1	LIM homeobox 1	0.013
HES2	hairy and enhancer of split 2 (Drosophila)	0.013
XIAP	X-linked inhibitor of apoptosis	0.013
MOS	v-mos Moloney murine sarcoma viral oncogene homolog	0.013
EPRS	glutamyl-prolyl-tRNA synthetase	0.013
MAPKAPK3	mitogen-activated protein kinase-activated protein kinase 3	0.013
ATF2	activating transcription factor 2	0.013
NOD1	nucleotide-binding oligomerization domain containing 1	0.013
POMC	proopiomelanocortin	0.013
NKX2-8	NK2 homeobox 8	0.013
AGPAT1	1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)	0.013
PIK3C2A	phosphoinositide-3-kinase, class 2, alpha polypeptide	0.013
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.013
BTG2	BTG family, member 2	0.013
LITAF	lipopolysaccharide-induced TNF factor	0.013
CUL4A	cullin 4A	0.013
MLKL	mixed lineage kinase domain-like	0.013
CREBZF	CREB/ATF bZIP transcription factor	0.013
JPH3	junctophilin 3	0.013
MED15	mediator complex subunit 15	0.013
E2F2	E2F transcription factor 2	0.013
GBX2	gastrulation brain homeobox 2	0.012
GOLGA6L9	golgin A6 family-like 9	0.012
AMN	amnionless homolog (mouse)	0.012
CALCA	calcitonin-related polypeptide alpha	0.012
KCNE1	potassium voltage-gated channel, Isk-related family, member 1	0.012
ZFP36L1	zinc finger protein 36, C3H type-like 1	0.012
PAPD7	PAP associated domain containing 7	0.012
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.012
PHC2	polyhomeotic homolog 2 (Drosophila)	0.012
MED26	mediator complex subunit 26	0.012
TBX1	T-box 1	0.012
SOX11	SRY (sex determining region Y)-box 11	0.012
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.012
DRD4	dopamine receptor D4	0.012
KLHL35	kelch-like 35 (Drosophila)	0.012
WT1	Wilms tumor 1	0.012
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.012
OLIG2	oligodendrocyte lineage transcription factor 2	0.012
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.012
PANX2	pannexin 2	0.012
PAX6	paired box 6	0.012
GADD45B	growth arrest and DNA-damage-inducible, beta	0.012
ASCC2	activating signal cointegrator 1 complex subunit 2	0.012
FNBP4	formin binding protein 4	0.012
BATF	basic leucine zipper transcription factor, ATF-like	0.012
MKNK2	MAP kinase interacting serine/threonine kinase 2	0.012
ZBTB7A	zinc finger and BTB domain containing 7A	0.012
LCOR	ligand dependent nuclear receptor corepressor	0.012
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.012
HRK	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.012
HOXB13	homeobox B13	0.012
IHH	Indian hedgehog	0.012
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.012
IRAK3	interleukin-1 receptor-associated kinase 3	0.011
LBX1	ladybird homeobox 1	0.011
FOSL2	FOS-like antigen 2	0.011
UBR1	ubiquitin protein ligase E3 component n-recognin 1	0.011
OFD1	oral-facial-digital syndrome 1	0.011
OTP	orthopedia homeobox	0.011
SCAF4	SR-related CTD-associated factor 4	0.011
GCH1	GTP cyclohydrolase 1	0.011
CTBP2	C-terminal binding protein 2	0.011
YY1	YY1 transcription factor	0.011
PHF11	PHD finger protein 11	0.011
ZNF12	zinc finger protein 12	0.011
KEAP1	kelch-like ECH-associated protein 1	0.011
BRD3	bromodomain containing 3	0.011
DHH	desert hedgehog	0.011
HOXD13	homeobox D13	0.011
DPF2	D4, zinc and double PHD fingers family 2	0.011
BAZ1A	bromodomain adjacent to zinc finger domain, 1A	0.011
XPO7	exportin 7	0.011
DTX3	deltex homolog 3 (Drosophila)	0.011
PAX7	paired box 7	0.011
BEGAIN	brain-enriched guanylate kinase-associated homolog (rat)	0.011
IRAK4	interleukin-1 receptor-associated kinase 4	0.011
HNF1A	HNF1 homeobox A	0.011
TMEM44	transmembrane protein 44	0.011
SBNO2	strawberry notch homolog 2 (Drosophila)	0.011
NEUROG3	neurogenin 3	0.011
LRCH3	leucine-rich repeats and calponin homology (CH) domain containing 3	0.011
RBM8A	RNA binding motif protein 8A	0.011
PHACTR3	phosphatase and actin regulator 3	0.011
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.011
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.011	Fly
NR2E1	nuclear receptor subfamily 2, group E, member 1	0.011
PIM1	pim-1 oncogene	0.011
CDX1	caudal type homeobox 1	0.011	Fly
RAB3GAP2	RAB3 GTPase activating protein subunit 2 (non-catalytic)	0.011
PML	promyelocytic leukemia	0.011
C10orf18	chromosome 10 open reading frame 18	0.011
AKAP8L	A kinase (PRKA) anchor protein 8-like	0.011
PSMB10	proteasome (prosome, macropain) subunit, beta type, 10	0.011
ATM	ataxia telangiectasia mutated	0.010
UBQLN1	ubiquilin 1	0.010
AHCTF1	AT hook containing transcription factor 1	0.010
NFATC3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	0.010
CCNJ	cyclin J	0.010
CITED1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	0.010
TIFA	TRAF-interacting protein with forkhead-associated domain	0.010
FKBP3	FK506 binding protein 3, 25kDa	0.010
NKX2-2	NK2 homeobox 2	0.010
MYSM1	Myb-like, SWIRM and MPN domains 1	0.010
GNL3L	guanine nucleotide binding protein-like 3 (nucleolar)-like	0.010
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.010
FOXL1	forkhead box L1	0.010
APAF1	apoptotic peptidase activating factor 1	0.010
APC2	adenomatosis polyposis coli 2	0.010
NKX6-1	NK6 homeobox 1	0.010
TRAF1	TNF receptor-associated factor 1	0.010
NEUROG1	neurogenin 1	0.010
MASP2	mannan-binding lectin serine peptidase 2	0.010
RBM45	RNA binding motif protein 45	0.010
BTN3A2	butyrophilin, subfamily 3, member A2	0.010
FGF3	fibroblast growth factor 3	0.010
KYNU	kynureninase	0.010
GHSR	growth hormone secretagogue receptor	0.010
PITX3	paired-like homeodomain 3	0.010
RBM4B	RNA binding motif protein 4B	0.010
ALPL	alkaline phosphatase, liver/bone/kidney	0.010
PRKD2	protein kinase D2	0.010
UPF3B	UPF3 regulator of nonsense transcripts homolog B (yeast)	0.010
DYNLT1	dynein, light chain, Tctex-type 1	0.010
IL1A	interleukin 1, alpha	0.010
HES5	hairy and enhancer of split 5 (Drosophila)	0.010
NLRP2	NLR family, pyrin domain containing 2	0.010