IMP

Process View

Homo sapiens

17 genes annotated in human

telencephalon development

The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "telencephalon development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "telencephalon development" (in gray)

Name	Description	Probability	Func Analog Organism
HDAC2	histone deacetylase 2	0.724	Mouse
PEX19	peroxisomal biogenesis factor 19	0.629
AKR1C2	aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)	0.591	Rat
HDAC1	histone deacetylase 1	0.577	Mouse
ESR1	estrogen receptor 1	0.561
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.520
GSK3B	glycogen synthase kinase 3 beta	0.456
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.434	Mouse
AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)	0.393	Rat
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.370
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.356
MAPT	microtubule-associated protein tau	0.319
SMAD2	SMAD family member 2	0.300
PEX14	peroxisomal biogenesis factor 14	0.282
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.254
SORBS3	sorbin and SH3 domain containing 3	0.252
BMPR1A	bone morphogenetic protein receptor, type IA	0.202
LAMB1	laminin, beta 1	0.175
TSC2	tuberous sclerosis 2	0.173
UBQLN1	ubiquilin 1	0.158
SOX2	SRY (sex determining region Y)-box 2	0.157	Mouse
PARP1	poly (ADP-ribose) polymerase 1	0.156
NDEL1	nudE nuclear distribution gene E homolog (A. nidulans)-like 1	0.152	Human Mouse
UBR1	ubiquitin protein ligase E3 component n-recognin 1	0.144
LAMC1	laminin, gamma 1 (formerly LAMB2)	0.135	Human
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.113
LRP6	low density lipoprotein receptor-related protein 6	0.112	Mouse
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.111
SCRIB	scribbled homolog (Drosophila)	0.110
QKI	quaking homolog, KH domain RNA binding (mouse)	0.110
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.100
TP53	tumor protein p53	0.099
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.099
PTCH1	patched 1	0.097
AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)	0.094	Rat
LAMA4	laminin, alpha 4	0.091
ZHX1	zinc fingers and homeoboxes 1	0.086
TADA2A	transcriptional adaptor 2A	0.086
SNTG2	syntrophin, gamma 2	0.084
DLG4	discs, large homolog 4 (Drosophila)	0.081
SCHIP1	schwannomin interacting protein 1	0.078
E2F1	E2F transcription factor 1	0.075
AXIN1	axin 1	0.073
PBX1	pre-B-cell leukemia homeobox 1	0.072
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.071
SRGAP2	SLIT-ROBO Rho GTPase activating protein 2	0.060	Mouse
RUNX1	runt-related transcription factor 1	0.060
FZD1	frizzled homolog 1 (Drosophila)	0.059
VEGFA	vascular endothelial growth factor A	0.058
FSTL1	follistatin-like 1	0.054
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.054
POU3F2	POU class 3 homeobox 2	0.053	Mouse
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.052
PAX8	paired box 8	0.051
APP	amyloid beta (A4) precursor protein	0.049
MKL1	megakaryoblastic leukemia (translocation) 1	0.049
TCF4	transcription factor 4	0.049
CSNK1E	casein kinase 1, epsilon	0.049
PPFIA1	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1	0.049
SIX3	SIX homeobox 3	0.048
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.048
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.048
SMAD3	SMAD family member 3	0.047
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.047
SOX11	SRY (sex determining region Y)-box 11	0.047
BCOR	BCL6 corepressor	0.046
COL1A1	collagen, type I, alpha 1	0.046
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.045
BBS9	Bardet-Biedl syndrome 9	0.045
ATXN1	ataxin 1	0.045
USP46	ubiquitin specific peptidase 46	0.044
ASB2	ankyrin repeat and SOCS box containing 2	0.043
PML	promyelocytic leukemia	0.043
TRRAP	transformation/transcription domain-associated protein	0.042
PLXND1	plexin D1	0.041
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.040
GATAD2B	GATA zinc finger domain containing 2B	0.037
SOX10	SRY (sex determining region Y)-box 10	0.037
MYOD1	myogenic differentiation 1	0.037
SNAPIN	SNAP-associated protein	0.036
SMAD1	SMAD family member 1	0.036
CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.036
RDX	radixin	0.036
COL1A2	collagen, type I, alpha 2	0.035
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.035
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.034
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.034
HOXC8	homeobox C8	0.034
RXRA	retinoid X receptor, alpha	0.034
MEIS2	Meis homeobox 2	0.034
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.034
PRTFDC1	phosphoribosyl transferase domain containing 1	0.034
BAK1	BCL2-antagonist/killer 1	0.033
SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.033	Human
CAMK2A	calcium/calmodulin-dependent protein kinase II alpha	0.033
NCOA1	nuclear receptor coactivator 1	0.032
CPE	carboxypeptidase E	0.031
RNF144B	ring finger protein 144B	0.031
PCM1	pericentriolar material 1	0.031
ADAMTSL4	ADAMTS-like 4	0.031
PDX1	pancreatic and duodenal homeobox 1	0.030
CREBBP	CREB binding protein	0.030
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	0.029
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.029	Mouse
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.029
AR	androgen receptor	0.029
RAX	retina and anterior neural fold homeobox	0.029
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.029
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.029
LHX2	LIM homeobox 2	0.029	Zebrafish Mouse
DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	0.028
BCL2	B-cell CLL/lymphoma 2	0.028
SPTBN4	spectrin, beta, non-erythrocytic 4	0.028
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.028
PEX12	peroxisomal biogenesis factor 12	0.028
SORBS1	sorbin and SH3 domain containing 1	0.028
HNF4A	hepatocyte nuclear factor 4, alpha	0.027
PAX6	paired box 6	0.027	Mouse Rat
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.027
APTX	aprataxin	0.026
POU5F1	POU class 5 homeobox 1	0.025
USP22	ubiquitin specific peptidase 22	0.025
AP2A1	adaptor-related protein complex 2, alpha 1 subunit	0.025
TRIB3	tribbles homolog 3 (Drosophila)	0.025
APC	adenomatous polyposis coli	0.025
PTPRD	protein tyrosine phosphatase, receptor type, D	0.024
BID	BH3 interacting domain death agonist	0.024
PDIA3	protein disulfide isomerase family A, member 3	0.024
SOX1	SRY (sex determining region Y)-box 1	0.024
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.024
PAX3	paired box 3	0.024
ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	0.024
HMGA2	high mobility group AT-hook 2	0.024
CAV1	caveolin 1, caveolae protein, 22kDa	0.023
DLG2	discs, large homolog 2 (Drosophila)	0.023
MED25	mediator complex subunit 25	0.023
SOX21	SRY (sex determining region Y)-box 21	0.023
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.023	Rat
PTPRC	protein tyrosine phosphatase, receptor type, C	0.023
PIN1	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	0.022
FOXG1	forkhead box G1	0.022	Mouse
SPG21	spastic paraplegia 21 (autosomal recessive, Mast syndrome)	0.022
SALL2	sal-like 2 (Drosophila)	0.022	Human
PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.022
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.022
BBS2	Bardet-Biedl syndrome 2	0.022
MTA3	metastasis associated 1 family, member 3	0.022
KCTD17	potassium channel tetramerisation domain containing 17	0.021
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.021
BBS1	Bardet-Biedl syndrome 1	0.021
BCL2L1	BCL2-like 1	0.021
FEZF2	FEZ family zinc finger 2	0.021	Mouse
FZD8	frizzled homolog 8 (Drosophila)	0.020
PRKCZ	protein kinase C, zeta	0.020
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.020
CLIP1	CAP-GLY domain containing linker protein 1	0.020
DUSP23	dual specificity phosphatase 23	0.020
ERBB2IP	erbb2 interacting protein	0.020
ATN1	atrophin 1	0.020
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.020
CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.019	Mouse
SPTBN1	spectrin, beta, non-erythrocytic 1	0.019
ALX4	ALX homeobox 4	0.019
DISC1	disrupted in schizophrenia 1	0.019	Mouse
MARCKS	myristoylated alanine-rich protein kinase C substrate	0.019
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.019
RPL18A	ribosomal protein L18a	0.018
TMEM173	transmembrane protein 173	0.018
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.018
MMP16	matrix metallopeptidase 16 (membrane-inserted)	0.018
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.018
CHD8	chromodomain helicase DNA binding protein 8	0.018
PKP4	plakophilin 4	0.018
BCL6	B-cell CLL/lymphoma 6	0.018
FBLN1	fibulin 1	0.018
BMP7	bone morphogenetic protein 7	0.018
WDYHV1	WDYHV motif containing 1	0.018
RHOXF2	Rhox homeobox family, member 2	0.018
SST	somatostatin	0.018
FGF3	fibroblast growth factor 3	0.018
MTA1	metastasis associated 1	0.017
EGFR	epidermal growth factor receptor	0.017
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.017
FASLG	Fas ligand (TNF superfamily, member 6)	0.017
GRIN1	glutamate receptor, ionotropic, N-methyl D-aspartate 1	0.017	Mouse
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.017
NOVA2	neuro-oncological ventral antigen 2	0.017
FGF2	fibroblast growth factor 2 (basic)	0.017
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.017
SFRP1	secreted frizzled-related protein 1	0.016
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.016
WDR20	WD repeat domain 20	0.016
ALK	anaplastic lymphoma receptor tyrosine kinase	0.016
SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.016	Human
NKX2-2	NK2 homeobox 2	0.016
FZD7	frizzled homolog 7 (Drosophila)	0.016
PLXNB2	plexin B2	0.016
DCTN1	dynactin 1	0.016
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.016
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.016
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	0.016
CENPE	centromere protein E, 312kDa	0.016
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.016
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.016
DPYSL2	dihydropyrimidinase-like 2	0.016
HOXD12	homeobox D12	0.015
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.015	Rat
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.015
WDFY3	WD repeat and FYVE domain containing 3	0.015
LBX1	ladybird homeobox 1	0.015
JAG1	jagged 1	0.015
BAI1	brain-specific angiogenesis inhibitor 1	0.015
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.015
IGF1R	insulin-like growth factor 1 receptor	0.015
COL5A2	collagen, type V, alpha 2	0.015
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.015
PDE4D	phosphodiesterase 4D, cAMP-specific	0.015
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.015	Mouse
NKX6-1	NK6 homeobox 1	0.015
RAD23B	RAD23 homolog B (S. cerevisiae)	0.015
EFEMP2	EGF containing fibulin-like extracellular matrix protein 2	0.014
COL5A1	collagen, type V, alpha 1	0.014
RARA	retinoic acid receptor, alpha	0.014	Rat
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.014
MYOCD	myocardin	0.014
MSX1	msh homeobox 1	0.014
COL18A1	collagen, type XVIII, alpha 1	0.014
FGF1	fibroblast growth factor 1 (acidic)	0.014
POU3F1	POU class 3 homeobox 1	0.014
KIF1C	kinesin family member 1C	0.014
RNR2	l-rRNA	0.014
FGFR2	fibroblast growth factor receptor 2	0.014
NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	0.014
HDAC6	histone deacetylase 6	0.014
MAP2K6	mitogen-activated protein kinase kinase 6	0.014
LAMA5	laminin, alpha 5	0.014
C1QL1	complement component 1, q subcomponent-like 1	0.013
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.013	Mouse
PAX7	paired box 7	0.013
NLK	nemo-like kinase	0.013
ASB7	ankyrin repeat and SOCS box containing 7	0.013
TGFB2	transforming growth factor, beta 2	0.013
NPAS3	neuronal PAS domain protein 3	0.013
MAP1B	microtubule-associated protein 1B	0.013
KALRN	kalirin, RhoGEF kinase	0.013
DLGAP1	discs, large (Drosophila) homolog-associated protein 1	0.013
TTK	TTK protein kinase	0.013
KAT5	K(lysine) acetyltransferase 5	0.013
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.013
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.013
SMAD9	SMAD family member 9	0.013
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.013
PPARA	peroxisome proliferator-activated receptor alpha	0.013
RTKN	rhotekin	0.013
ASB1	ankyrin repeat and SOCS box containing 1	0.013
COL4A3BP	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	0.013
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.013
MEIS1	Meis homeobox 1	0.013
NCOR2	nuclear receptor corepressor 2	0.013	Mouse
ZIC3	Zic family member 3 (odd-paired homolog, Drosophila)	0.012
SH3RF1	SH3 domain containing ring finger 1	0.012
BNC2	basonuclin 2	0.012
PTPRN	protein tyrosine phosphatase, receptor type, N	0.012
PCDH17	protocadherin 17	0.012
LHX3	LIM homeobox 3	0.012
SNX27	sorting nexin family member 27	0.012
GLI3	GLI family zinc finger 3	0.012	Mouse
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.012
OLIG2	oligodendrocyte lineage transcription factor 2	0.012
FERMT2	fermitin family member 2	0.012
NEUROD1	neurogenic differentiation 1	0.012	Mouse
NFIA	nuclear factor I/A	0.012
OTX2	orthodenticle homeobox 2	0.012
RBMS3	RNA binding motif, single stranded interacting protein 3	0.012
ANTXR2	anthrax toxin receptor 2	0.012
DLL3	delta-like 3 (Drosophila)	0.012
FGF8	fibroblast growth factor 8 (androgen-induced)	0.012
PTPRF	protein tyrosine phosphatase, receptor type, F	0.012
KCNQ2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.012
ZFYVE9	zinc finger, FYVE domain containing 9	0.011
ARIH2	ariadne homolog 2 (Drosophila)	0.011
ITGB4	integrin, beta 4	0.011
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.011	Mouse
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.011
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.011
ADORA2A	adenosine A2a receptor	0.011
LIG3	ligase III, DNA, ATP-dependent	0.011
GRIN2C	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	0.011
SIX6	SIX homeobox 6	0.011
SORBS2	sorbin and SH3 domain containing 2	0.011
EMX1	empty spiracles homeobox 1	0.011	Mouse
MEF2A	myocyte enhancer factor 2A	0.011
SLIT2	slit homolog 2 (Drosophila)	0.011
CKAP5	cytoskeleton associated protein 5	0.011
UBE2G1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	0.011
ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.011
RASAL2	RAS protein activator like 2	0.011
DAB2IP	DAB2 interacting protein	0.011	Mouse
MBD2	methyl-CpG binding domain protein 2	0.011
BARX1	BARX homeobox 1	0.011
ASCL1	achaete-scute complex homolog 1 (Drosophila)	0.011	Mouse
FABP7	fatty acid binding protein 7, brain	0.011
AXIN2	axin 2	0.011
ACAN	aggrecan	0.011
HCN4	hyperpolarization activated cyclic nucleotide-gated potassium channel 4	0.011
EGR3	early growth response 3	0.010
CHRDL1	chordin-like 1	0.010
NFIB	nuclear factor I/B	0.010	Mouse
SOX9	SRY (sex determining region Y)-box 9	0.010
CAMK2B	calcium/calmodulin-dependent protein kinase II beta	0.010
HRH3	histamine receptor H3	0.010
SUV39H1	suppressor of variegation 3-9 homolog 1 (Drosophila)	0.010
DPYSL5	dihydropyrimidinase-like 5	0.010
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.010
SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.010
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.010
TRO	trophinin	0.010
ZMYND11	zinc finger, MYND-type containing 11	0.010
KAT2B	K(lysine) acetyltransferase 2B	0.010