IMP

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Mus musculus

28 genes annotated in mouse

Multi-species View

positive regulation of immunoglobulin production

GO:0002639

Any process that activates or increases the frequency, rate, or extent of immunoglobulin production.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of immunoglobulin production"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of immunoglobulin production" (in gray)

Name	Description	Probability	Func Analog Organism
Ifng	interferon gamma	0.826
Ccl2	chemokine (C-C motif) ligand 2	0.740
Fyn	Fyn proto-oncogene	0.734
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.695	Mouse
Foxp3	forkhead box P3	0.695	Mouse
Stat5b	signal transducer and activator of transcription 5B	0.669	Mouse
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.623
Tbx3	T-box 3	0.522	Mouse
Socs1	suppressor of cytokine signaling 1	0.511
Lyz2	lysozyme 2	0.452
Cd28	CD28 antigen	0.436
Il10	interleukin 10	0.422
Tlr4	toll-like receptor 4	0.415
Pitx1	paired-like homeodomain transcription factor 1	0.400
Csf1	colony stimulating factor 1 (macrophage)	0.385
Pitx2	paired-like homeodomain transcription factor 2	0.345
Ccl7	chemokine (C-C motif) ligand 7	0.330	Mouse
Ccr2	chemokine (C-C motif) receptor 2	0.317
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.262
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.203
Irf9	interferon regulatory factor 9	0.201
Tnf	tumor necrosis factor	0.197
Ccr1	chemokine (C-C motif) receptor 1	0.196
Stat5a	signal transducer and activator of transcription 5A	0.181	Mouse
Stat3	signal transducer and activator of transcription 3	0.178	Mouse
Pdcd1	programmed cell death 1	0.172
Il6st	interleukin 6 signal transducer	0.168
Il6	interleukin 6	0.162	Human
Fasl	Fas ligand (TNF superfamily, member 6)	0.147
Wt1	Wilms tumor 1 homolog	0.143
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.139	Mouse
Tbx5	T-box 5	0.139	Mouse
Ccr7	chemokine (C-C motif) receptor 7	0.130
Il2	interleukin 2	0.126
Itga3	integrin alpha 3	0.126
Prf1	perforin 1 (pore forming protein)	0.117
Fas	Fas (TNF receptor superfamily member 6)	0.103
Il4	interleukin 4	0.098
Ccl8	chemokine (C-C motif) ligand 8	0.096
Hoxa1	homeobox A1	0.094
Noto	notochord homolog (Xenopus laevis)	0.083
Ptgs2	prostaglandin-endoperoxide synthase 2	0.082
Tcra	T-cell receptor alpha chain	0.076
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.072
Selp	selectin, platelet	0.072
Il1r1	interleukin 1 receptor, type I	0.072
Nos2	nitric oxide synthase 2, inducible	0.071
Mmp9	matrix metallopeptidase 9	0.071
Nckap1l	NCK associated protein 1 like	0.070
Icos	inducible T-cell co-stimulator	0.069	Mouse
Ccr5	chemokine (C-C motif) receptor 5	0.067
C3ar1	complement component 3a receptor 1	0.067
Batf	basic leucine zipper transcription factor, ATF-like	0.067
Fgfr2	fibroblast growth factor receptor 2	0.059
Sall1	sal-like 1 (Drosophila)	0.057
Fgf10	fibroblast growth factor 10	0.056
Cd5	CD5 antigen	0.056
Scn5a	sodium channel, voltage-gated, type V, alpha	0.056
Ly9	lymphocyte antigen 9	0.054
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.052
Cxcl2	chemokine (C-X-C motif) ligand 2	0.051
Rag2	recombination activating gene 2	0.051
Il13	interleukin 13	0.049
Mmp3	matrix metallopeptidase 3	0.047
Lcp1	lymphocyte cytosolic protein 1	0.047
Cd7	CD7 antigen	0.046
Rag1	recombination activating gene 1	0.044
Il4ra	interleukin 4 receptor, alpha	0.044
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.044
Il10ra	interleukin 10 receptor, alpha	0.044
Ccl3	chemokine (C-C motif) ligand 3	0.044	Mouse
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.042
Il1rl1	interleukin 1 receptor-like 1	0.042
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.041
Ch25h	cholesterol 25-hydroxylase	0.040
Pou5f1	POU domain, class 5, transcription factor 1	0.040
Pax2	paired box gene 2	0.040
Lag3	lymphocyte-activation gene 3	0.040
Lta	lymphotoxin A	0.038
Nanog	Nanog homeobox	0.037
Gja5	gap junction protein, alpha 5	0.036
Sh2d2a	SH2 domain protein 2A	0.036
Sall4	sal-like 4 (Drosophila)	0.036
Gzma	granzyme A	0.035
Pdcd1lg2	programmed cell death 1 ligand 2	0.035
Rxra	retinoid X receptor alpha	0.035
Jak2	Janus kinase 2	0.034
Gzmk	granzyme K	0.034
Ccl12	chemokine (C-C motif) ligand 12	0.034	Mouse
Btk	Bruton agammaglobulinemia tyrosine kinase	0.033
Ubd	ubiquitin D	0.033
Ifnar2	interferon (alpha and beta) receptor 2	0.032
Il2rb	interleukin 2 receptor, beta chain	0.032
Mmp12	matrix metallopeptidase 12	0.031
Was	Wiskott-Aldrich syndrome homolog (human)	0.030
Cd247	CD247 antigen	0.030
Lcp2	lymphocyte cytosolic protein 2	0.030
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.029	Mouse
Cxcl1	chemokine (C-X-C motif) ligand 1	0.029
Tbx4	T-box 4	0.028	Mouse
Chd7	chromodomain helicase DNA binding protein 7	0.028
Foxp2	forkhead box P2	0.028	Mouse
Ccl9	chemokine (C-C motif) ligand 9	0.028	Mouse
Shh	sonic hedgehog	0.027
Folr2	folate receptor 2 (fetal)	0.027
Dll4	delta-like 4 (Drosophila)	0.027
Nfil3	nuclear factor, interleukin 3, regulated	0.027
Inpp5d	inositol polyphosphate-5-phosphatase D	0.027
Runx3	runt related transcription factor 3	0.027
Cd19	CD19 antigen	0.027
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.026
Gimap7	GTPase, IMAP family member 7	0.026
Ccr6	chemokine (C-C motif) receptor 6	0.026
Ccl4	chemokine (C-C motif) ligand 4	0.025	Mouse
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.025
Msr1	macrophage scavenger receptor 1	0.025
Cd40lg	CD40 ligand	0.025
Cd84	CD84 antigen	0.025
Cd47	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)	0.024
Mx2	myxovirus (influenza virus) resistance 2	0.024
Stat1	signal transducer and activator of transcription 1	0.024	Mouse
Foxp1	forkhead box P1	0.024
Ctss	cathepsin S	0.024
Myd88	myeloid differentiation primary response gene 88	0.024
Snai1	snail homolog 1 (Drosophila)	0.024
Cd8a	CD8 antigen, alpha chain	0.023
Ccl22	chemokine (C-C motif) ligand 22	0.023
Vangl2	vang-like 2 (van gogh, Drosophila)	0.023
Foxc2	forkhead box C2	0.023
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.023
Il27ra	interleukin 27 receptor, alpha	0.023
Ighmbp2	immunoglobulin mu binding protein 2	0.023
Has2	hyaluronan synthase 2	0.023
Ilk	integrin linked kinase	0.022
Stx11	syntaxin 11	0.022
Vhl	von Hippel-Lindau tumor suppressor	0.022
Otx2	orthodenticle homolog 2 (Drosophila)	0.022
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.022
Ccl17	chemokine (C-C motif) ligand 17	0.022	Mouse
Plek	pleckstrin	0.021
Irg1	immunoresponsive gene 1	0.021
Laptm5	lysosomal-associated protein transmembrane 5	0.021
Jak1	Janus kinase 1	0.021
Cd4	CD4 antigen	0.020
Tcf21	transcription factor 21	0.020
Itgb2	integrin beta 2	0.020
Agap2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.020
Cxcl9	chemokine (C-X-C motif) ligand 9	0.020
Il7r	interleukin 7 receptor	0.019
Tnni2	troponin I, skeletal, fast 2	0.019
Hand2	heart and neural crest derivatives expressed transcript 2	0.019
Alx1	ALX homeobox 1	0.019
Gli2	GLI-Kruppel family member GLI2	0.019
Vcam1	vascular cell adhesion molecule 1	0.019
Lama5	laminin, alpha 5	0.018
Npy2r	neuropeptide Y receptor Y2	0.018
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.018
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.018
Cd8b1	CD8 antigen, beta chain 1	0.018
H6pd	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	0.018
Runx2	runt related transcription factor 2	0.018
Foxg1	forkhead box G1	0.018
Icam1	intercellular adhesion molecule 1	0.018
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.018
Foxf1a	forkhead box F1a	0.018
Clec4a2	C-type lectin domain family 4, member a2	0.018
Gata6	GATA binding protein 6	0.017
Mmp13	matrix metallopeptidase 13	0.017
Il2ra	interleukin 2 receptor, alpha chain	0.017
Il21r	interleukin 21 receptor	0.017
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.017
Chl1	cell adhesion molecule with homology to L1CAM	0.017
Clec4d	C-type lectin domain family 4, member d	0.017
H2-D1	histocompatibility 2, D region locus 1	0.017
Tnks1bp1	tankyrase 1 binding protein 1	0.017
Col13a1	collagen, type XIII, alpha 1	0.017
Lepr	leptin receptor	0.017
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.017
Zic3	zinc finger protein of the cerebellum 3	0.017
Ccl20	chemokine (C-C motif) ligand 20	0.017
Spna1	spectrin alpha 1	0.017
Nkg7	natural killer cell group 7 sequence	0.017
Aldh1a3	aldehyde dehydrogenase family 1, subfamily A3	0.016
Cxcl13	chemokine (C-X-C motif) ligand 13	0.016
Cd96	CD96 antigen	0.016
Itgax	integrin alpha X	0.016
Madcam1	mucosal vascular addressin cell adhesion molecule 1	0.016
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.016
Sh2d1a	SH2 domain protein 1A	0.016
Smad6	MAD homolog 6 (Drosophila)	0.016
Gdnf	glial cell line derived neurotrophic factor	0.016
Birc3	baculoviral IAP repeat-containing 3	0.016
Lpxn	leupaxin	0.015
Il1r2	interleukin 1 receptor, type II	0.015
Twist2	twist homolog 2 (Drosophila)	0.015
Traf1	TNF receptor-associated factor 1	0.015
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.015
Gm12185	predicted gene 12185	0.015
Cd14	CD14 antigen	0.015
Vegfa	vascular endothelial growth factor A	0.015
Tnfrsf18	tumor necrosis factor receptor superfamily, member 18	0.015
Lck	lymphocyte protein tyrosine kinase	0.015
Bmp5	bone morphogenetic protein 5	0.015
Vav1	vav 1 oncogene	0.015
Ptgir	prostaglandin I receptor (IP)	0.015
Foxn1	forkhead box N1	0.014
Fgf3	fibroblast growth factor 3	0.014
Cd3d	CD3 antigen, delta polypeptide	0.014
Rhoh	ras homolog gene family, member H	0.014
Mmp10	matrix metallopeptidase 10	0.014
Il13ra2	interleukin 13 receptor, alpha 2	0.014
Il3	interleukin 3	0.014
Gpr132	G protein-coupled receptor 132	0.014
Eya1	eyes absent 1 homolog (Drosophila)	0.014
Cxcl5	chemokine (C-X-C motif) ligand 5	0.014
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.014
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.014
Clec4n	C-type lectin domain family 4, member n	0.014
Adora2b	adenosine A2b receptor	0.014
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.014
Hoxa10	homeobox A10	0.014
Cd6	CD6 antigen	0.014
Srgn	serglycin	0.014
Cxcl10	chemokine (C-X-C motif) ligand 10	0.013
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.013
Tnfaip8l2	tumor necrosis factor, alpha-induced protein 8-like 2	0.013
Xcl1	chemokine (C motif) ligand 1	0.013
Wnt2	wingless-related MMTV integration site 2	0.013
Foxb1	forkhead box B1	0.013
Trim21	tripartite motif-containing 21	0.013
Lef1	lymphoid enhancer binding factor 1	0.013
Col4a3	collagen, type IV, alpha 3	0.013
Saa3	serum amyloid A 3	0.013
Irf4	interferon regulatory factor 4	0.013
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.013
B2m	beta-2 microglobulin	0.013
Arid1b	AT rich interactive domain 1B (SWI-like)	0.013
Rab27a	RAB27A, member RAS oncogene family	0.013
Tbx2	T-box 2	0.013	Mouse
Gzmb	granzyme B	0.013
Plekho2	pleckstrin homology domain containing, family O member 2	0.013
Sele	selectin, endothelial cell	0.013
Bcl2	B-cell leukemia/lymphoma 2	0.013
Gata4	GATA binding protein 4	0.013
Gata3	GATA binding protein 3	0.013
Card11	caspase recruitment domain family, member 11	0.013
Meox1	mesenchyme homeobox 1	0.013
Tbx21	T-box 21	0.013
Lif	leukemia inhibitory factor	0.012
Hoxa13	homeobox A13	0.012
Gpr65	G-protein coupled receptor 65	0.012
Sox2	SRY-box containing gene 2	0.012
Arid5a	AT rich interactive domain 5A (MRF1-like)	0.012
Apbb1ip	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	0.012
Card10	caspase recruitment domain family, member 10	0.012
Gp49a	glycoprotein 49 A	0.012
Rhod	ras homolog gene family, member D	0.012
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.012
Serp1	stress-associated endoplasmic reticulum protein 1	0.012
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.012
Nfatc4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.012
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.012
Cd40	CD40 antigen	0.012
Nog	noggin	0.012
Ltb	lymphotoxin B	0.011
Rybp	RING1 and YY1 binding protein	0.011
Nlrp3	NLR family, pyrin domain containing 3	0.011
Il18r1	interleukin 18 receptor 1	0.011
Gm11428	predicted gene 11428	0.011
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.011
Litaf	LPS-induced TN factor	0.011
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.011
Ccr8	chemokine (C-C motif) receptor 8	0.011
Pgf	placental growth factor	0.011
Jag1	jagged 1	0.011
Tnfsf8	tumor necrosis factor (ligand) superfamily, member 8	0.011
Nos3	nitric oxide synthase 3, endothelial cell	0.011
Bdkrb1	bradykinin receptor, beta 1	0.011
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.011
Jak3	Janus kinase 3	0.011
Osmr	oncostatin M receptor	0.011
Dlx5	distal-less homeobox 5	0.011
Myf6	myogenic factor 6	0.011
Wnt2b	wingless related MMTV integration site 2b	0.011
Ctsk	cathepsin K	0.011
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.011
Cytip	cytohesin 1 interacting protein	0.011
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.011
Egfr	epidermal growth factor receptor	0.011
Hira	histone cell cycle regulation defective homolog A (S. cerevisiae)	0.011
Slamf6	SLAM family member 6	0.010
Spp1	secreted phosphoprotein 1	0.010
Snx20	sorting nexin 20	0.010
Il25	interleukin 25	0.010
Tph1	tryptophan hydroxylase 1	0.010
Retnla	resistin like alpha	0.010
Il1a	interleukin 1 alpha	0.010
Nkx3-2	NK3 homeobox 2	0.010
Clcn1	chloride channel 1	0.010
Tnfaip6	tumor necrosis factor alpha induced protein 6	0.010
Gdf15	growth differentiation factor 15	0.010
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.010
Nr2f6	nuclear receptor subfamily 2, group F, member 6	0.010
Irx3	Iroquois related homeobox 3 (Drosophila)	0.010
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.010
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.010