IMP

Process View

Mus musculus

4 genes annotated in mouse

cellular response to peptidoglycan

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to peptidoglycan"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cellular response to peptidoglycan" (in gray)

Name	Description	Probability	Func Analog Organism
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.999
Myd88	myeloid differentiation primary response gene 88	0.998
Cd44	CD44 antigen	0.997
Mefv	Mediterranean fever	0.996
Ccr2	chemokine (C-C motif) receptor 2	0.986
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.980
Ticam1	toll-like receptor adaptor molecule 1	0.978
Ccl2	chemokine (C-C motif) ligand 2	0.971
Lyz2	lysozyme 2	0.933
Il1r1	interleukin 1 receptor, type I	0.884
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.785
Cd300ld	CD300 molecule-like family member d	0.724
Nlrp3	NLR family, pyrin domain containing 3	0.723	Mouse
Trem3	triggering receptor expressed on myeloid cells 3	0.675
Cd33	CD33 antigen	0.623
Siglece	sialic acid binding Ig-like lectin E	0.615
Casp1	caspase 1	0.575
Pilra	paired immunoglobin-like type 2 receptor alpha	0.574
Mmp9	matrix metallopeptidase 9	0.557
Fcgr4	Fc receptor, IgG, low affinity IV	0.538
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.532
Ticam2	toll-like receptor adaptor molecule 2	0.502
Tnf	tumor necrosis factor	0.497
Pilrb1	paired immunoglobin-like type 2 receptor beta 1	0.488
Cd14	CD14 antigen	0.471
Clec4n	C-type lectin domain family 4, member n	0.469
Spp1	secreted phosphoprotein 1	0.469
Clec7a	C-type lectin domain family 7, member a	0.458
Lair1	leukocyte-associated Ig-like receptor 1	0.444
Il1f9	interleukin 1 family, member 9	0.378
Il1b	interleukin 1 beta	0.371
Pycard	PYD and CARD domain containing	0.351
BC013712	cDNA sequence BC013712	0.341
Il1rn	interleukin 1 receptor antagonist	0.275
Cd300lf	CD300 antigen like family member F	0.261	Mouse
Irak4	interleukin-1 receptor-associated kinase 4	0.257
Gpr35	G protein-coupled receptor 35	0.247
Casp8	caspase 8	0.244
Cd84	CD84 antigen	0.225
AF251705	cDNA sequence AF251705	0.217	Mouse
Unc93b1	unc-93 homolog B1 (C. elegans)	0.213
Trpv1	transient receptor potential cation channel, subfamily V, member 1	0.207
Igsf6	immunoglobulin superfamily, member 6	0.189
Trem1	triggering receptor expressed on myeloid cells 1	0.181
Hk3	hexokinase 3	0.160
Slamf8	SLAM family member 8	0.159
Msr1	macrophage scavenger receptor 1	0.157
Nfam1	Nfat activating molecule with ITAM motif 1	0.157
Irg1	immunoresponsive gene 1	0.151
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	0.149
Cd300lb	CD300 antigen like family member B	0.148	Mouse
Naip6	NLR family, apoptosis inhibitory protein 6	0.136
Mb	myoglobin	0.133
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.130
Stat3	signal transducer and activator of transcription 3	0.129
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.125
Ly96	lymphocyte antigen 96	0.125
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.124
Emr4	EGF-like module containing, mucin-like, hormone receptor-like sequence 4	0.120
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.120
Tifab	TRAF-interacting protein with forkhead-associated domain, family member B	0.116
Btk	Bruton agammaglobulinemia tyrosine kinase	0.115
Stx11	syntaxin 11	0.115
Fadd	Fas (TNFRSF6)-associated via death domain	0.112
Clec5a	C-type lectin domain family 5, member a	0.112
Apobr	apolipoprotein B receptor	0.108
Birc3	baculoviral IAP repeat-containing 3	0.104
Clec4d	C-type lectin domain family 4, member d	0.098
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.098
Tlr6	toll-like receptor 6	0.097	Mouse
Lepr	leptin receptor	0.088
Il6	interleukin 6	0.086
Clec4a2	C-type lectin domain family 4, member a2	0.083
Klra17	killer cell lectin-like receptor, subfamily A, member 17	0.080
Abcg3	ATP-binding cassette, sub-family G (WHITE), member 3	0.078
Naip2	NLR family, apoptosis inhibitory protein 2	0.076
Clec4b1	C-type lectin domain family 4, member b1	0.073
Cysltr1	cysteinyl leukotriene receptor 1	0.070
Havcr2	hepatitis A virus cellular receptor 2	0.069
Cd300a	CD300A antigen	0.064	Mouse
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.063
5430435G22Rik	RIKEN cDNA 5430435G22 gene	0.062
Sirpb1a	signal-regulatory protein beta 1A	0.062
Dok3	docking protein 3	0.061
Pparg	peroxisome proliferator activated receptor gamma	0.059
Gm11428	predicted gene 11428	0.057
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.056
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.055
Tcfec	transcription factor EC	0.055
Itch	itchy, E3 ubiquitin protein ligase	0.054
Traf6	TNF receptor-associated factor 6	0.053
Fpr1	formyl peptide receptor 1	0.052
Nos2	nitric oxide synthase 2, inducible	0.051
Evi2b	ecotropic viral integration site 2b	0.051
B430306N03Rik	RIKEN cDNA B430306N03 gene	0.050
1810033B17Rik	RIKEN cDNA 1810033B17 gene	0.049
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.048
Irak3	interleukin-1 receptor-associated kinase 3	0.048
Il6st	interleukin 6 signal transducer	0.047
Tlr1	toll-like receptor 1	0.046	Mouse
Fas	Fas (TNF receptor superfamily member 6)	0.044
Hck	hemopoietic cell kinase	0.044
AB124611	cDNA sequence AB124611	0.044
Gpr84	G protein-coupled receptor 84	0.044
F7	coagulation factor VII	0.044
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.042
Il1a	interleukin 1 alpha	0.042
Tlr4	toll-like receptor 4	0.041	Mouse
Csprs	component of Sp100-rs	0.041
Slc15a3	solute carrier family 15, member 3	0.041
P2ry13	purinergic receptor P2Y, G-protein coupled 13	0.040
Hpgds	hematopoietic prostaglandin D synthase	0.040
Ccr1	chemokine (C-C motif) receptor 1	0.040
Naip5	NLR family, apoptosis inhibitory protein 5	0.040
C3	complement component 3	0.039
Mrgpra2a	MAS-related GPR, member A2A	0.039
Mmp12	matrix metallopeptidase 12	0.039
C130050O18Rik	RIKEN cDNA C130050O18 gene	0.038
Ms4a7	membrane-spanning 4-domains, subfamily A, member 7	0.038
Mlkl	mixed lineage kinase domain-like	0.038
Niacr1	niacin receptor 1	0.038
Ms4a8a	membrane-spanning 4-domains, subfamily A, member 8A	0.037
Cybb	cytochrome b-245, beta polypeptide	0.036
Hcst	hematopoietic cell signal transducer	0.035
Pira2	paired-Ig-like receptor A2	0.035
Sykb	spleen tyrosine kinase	0.035
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.034
Mpeg1	macrophage expressed gene 1	0.033
Aim2	absent in melanoma 2	0.033
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.033
Il4ra	interleukin 4 receptor, alpha	0.033
Irak1	interleukin-1 receptor-associated kinase 1	0.032
Mmp8	matrix metallopeptidase 8	0.032
Ifnar1	interferon (alpha and beta) receptor 1	0.032
Tlr13	toll-like receptor 13	0.031
Hif1a	hypoxia inducible factor 1, alpha subunit	0.031
Tnfrsf14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.031
Tifa	TRAF-interacting protein with forkhead-associated domain	0.030
Tmem106a	transmembrane protein 106A	0.030
Rab32	RAB32, member RAS oncogene family	0.030
Socs3	suppressor of cytokine signaling 3	0.030
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.029
Kmo	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.029
Ern1	endoplasmic reticulum (ER) to nucleus signalling 1	0.029
Cyp4f18	cytochrome P450, family 4, subfamily f, polypeptide 18	0.028
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.028
Aldh3b1	aldehyde dehydrogenase 3 family, member B1	0.027
Fpr2	formyl peptide receptor 2	0.027
Tlr11	toll-like receptor 11	0.027	Mouse
Apbb1ip	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	0.027
Ldlr	low density lipoprotein receptor	0.027
Ccl7	chemokine (C-C motif) ligand 7	0.026
Gm7609	predicted pseudogene 7609	0.026
Tirap	toll-interleukin 1 receptor (TIR) domain-containing adaptor protein	0.026
Adap2	ArfGAP with dual PH domains 2	0.026
Gp2	glycoprotein 2 (zymogen granule membrane)	0.026
Lat2	linker for activation of T cells family, member 2	0.026
Gm885	predicted gene 885	0.025
Clec4e	C-type lectin domain family 4, member e	0.025
Cd209a	CD209a antigen	0.025
Icam1	intercellular adhesion molecule 1	0.025
Kynu	kynureninase (L-kynurenine hydrolase)	0.025
AI447881	expressed sequence AI447881	0.024
Ccl24	chemokine (C-C motif) ligand 24	0.024
Epsti1	epithelial stromal interaction 1 (breast)	0.024
Nlrp6	NLR family, pyrin domain containing 6	0.024	Mouse
Treml4	triggering receptor expressed on myeloid cells-like 4	0.024
Rgs18	regulator of G-protein signaling 18	0.024
Cd200r1	CD200 receptor 1	0.024
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.024
Itgb2	integrin beta 2	0.024
Slamf7	SLAM family member 7	0.024
Myo1g	myosin IG	0.023
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.023
Samsn1	SAM domain, SH3 domain and nuclear localization signals, 1	0.023
Pion	pigeon homolog (Drosophila)	0.023
Cxcl13	chemokine (C-X-C motif) ligand 13	0.023
Ikbkg	inhibitor of kappaB kinase gamma	0.023
LOC100038947	signal-regulatory protein beta 1-like	0.022
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.021
Inpp5d	inositol polyphosphate-5-phosphatase D	0.020
Tlr2	toll-like receptor 2	0.020
Plaur	plasminogen activator, urokinase receptor	0.020
Ccl9	chemokine (C-C motif) ligand 9	0.020
Cd177	CD177 antigen	0.020
2610528J11Rik	RIKEN cDNA 2610528J11 gene	0.020
C3ar1	complement component 3a receptor 1	0.020
Tlr9	toll-like receptor 9	0.019
Oasl1	2'-5' oligoadenylate synthetase-like 1	0.019
Slc37a2	solute carrier family 37 (glycerol-3-phosphate transporter), member 2	0.019
Lcp1	lymphocyte cytosolic protein 1	0.019
Apoc2	apolipoprotein C-II	0.019
Itgax	integrin alpha X	0.019
Tnfaip8l2	tumor necrosis factor, alpha-induced protein 8-like 2	0.019
Reg1	regenerating islet-derived 1	0.018
Snx20	sorting nexin 20	0.018
Adam8	a disintegrin and metallopeptidase domain 8	0.018
Pik3r5	phosphoinositide-3-kinase, regulatory subunit 5, p101	0.018
Ly6i	lymphocyte antigen 6 complex, locus I	0.018
Tmprss2	transmembrane protease, serine 2	0.018
Hfe	hemochromatosis	0.018
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.018	Mouse
1810011H11Rik	RIKEN cDNA 1810011H11 gene	0.017
Mbd3l1	methyl-CpG binding domain protein 3-like 1	0.017
Ccr6	chemokine (C-C motif) receptor 6	0.017
Ncf4	neutrophil cytosolic factor 4	0.017
Fyb	FYN binding protein	0.017
Sfpi1	SFFV proviral integration 1	0.017
Marveld3	MARVEL (membrane-associating) domain containing 3	0.017
Tlr8	toll-like receptor 8	0.016	Mouse
Gbp5	guanylate binding protein 5	0.016
Acox2	acyl-Coenzyme A oxidase 2, branched chain	0.016
Sult1c2	sulfotransferase family, cytosolic, 1C, member 2	0.016
Cyld	cylindromatosis (turban tumor syndrome)	0.016
Papln	papilin, proteoglycan-like sulfated glycoprotein	0.016
Gda	guanine deaminase	0.016
Clec2h	C-type lectin domain family 2, member h	0.016
Nhej1	nonhomologous end-joining factor 1	0.016
Tpcn2	two pore segment channel 2	0.016
Atp8b4	ATPase, class I, type 8B, member 4	0.016
Ifitm6	interferon induced transmembrane protein 6	0.016
Il18	interleukin 18	0.016
Pram1	PML-RAR alpha-regulated adaptor molecule 1	0.016
5430427O19Rik	RIKEN cDNA 5430427O19 gene	0.016
Tmem173	transmembrane protein 173	0.015
Pla2g2e	phospholipase A2, group IIE	0.015
Fcgr1	Fc receptor, IgG, high affinity I	0.015
Rgs1	regulator of G-protein signaling 1	0.015
Ms4a6b	membrane-spanning 4-domains, subfamily A, member 6B	0.015
Evi2a	ecotropic viral integration site 2a	0.015
Zc3h12d	zinc finger CCCH type containing 12D	0.015
Rnf186	ring finger protein 186	0.015
Gm6377	predicted gene 6377	0.014
Cxcl1	chemokine (C-X-C motif) ligand 1	0.014
Slamf9	SLAM family member 9	0.014
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.014
Slc13a2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2	0.014
Trim30b	tripartite motif-containing 30B	0.014
Klrb1f	killer cell lectin-like receptor subfamily B member 1F	0.014
Slpi	secretory leukocyte peptidase inhibitor	0.014
Dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58	0.014
Vtcn1	V-set domain containing T cell activation inhibitor 1	0.014
Gpnmb	glycoprotein (transmembrane) nmb	0.014
Saa1	serum amyloid A 1	0.014
Gpr65	G-protein coupled receptor 65	0.014
Lgals3	lectin, galactose binding, soluble 3	0.014
Itgb6	integrin beta 6	0.014
Cblb	Casitas B-lineage lymphoma b	0.014
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.014
Trim30d	tripartite motif-containing 30D	0.014
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.014
Tmem59	transmembrane protein 59	0.013
Gm12185	predicted gene 12185	0.013
Hrh4	histamine receptor H4	0.013
Gbgt1	globoside alpha-1,3-N-acetylgalactosaminyltransferase 1	0.013
Lpxn	leupaxin	0.013
Cxcl16	chemokine (C-X-C motif) ligand 16	0.013
Vwa5a	von Willebrand factor A domain containing 5A	0.013
Car9	carbonic anhydrase 9	0.013
Cxcl2	chemokine (C-X-C motif) ligand 2	0.013
Cfb	complement factor B	0.013
Proz	protein Z, vitamin K-dependent plasma glycoprotein	0.013
Spon2	spondin 2, extracellular matrix protein	0.013
2010003K11Rik	RIKEN cDNA 2010003K11 gene	0.013
BC026585	cDNA sequence BC026585	0.013
Treml1	triggering receptor expressed on myeloid cells-like 1	0.013
Tspan10	tetraspanin 10	0.013
Tnfrsf23	tumor necrosis factor receptor superfamily, member 23	0.013
Ptger2	prostaglandin E receptor 2 (subtype EP2)	0.012
Zc3h12a	zinc finger CCCH type containing 12A	0.012
Bcl2a1d	B-cell leukemia/lymphoma 2 related protein A1d	0.012
Stfa3	stefin A3	0.012
Slc13a1	solute carrier family 13 (sodium/sulfate symporters), member 1	0.012
Plac8	placenta-specific 8	0.012
Atp6v0d2	ATPase, H+ transporting, lysosomal V0 subunit D2	0.012
March1	membrane-associated ring finger (C3HC4) 1	0.012
Tbxas1	thromboxane A synthase 1, platelet	0.012
Slfn2	schlafen 2	0.012
Slfn4	schlafen 4	0.012
Slc2a9	solute carrier family 2 (facilitated glucose transporter), member 9	0.012
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.012
Tm7sf4	transmembrane 7 superfamily member 4	0.012
Mmp19	matrix metallopeptidase 19	0.012
Vill	villin-like	0.012
Cfhr2	complement factor H-related 2	0.012
Tmc5	transmembrane channel-like gene family 5	0.012
Slc22a13	solute carrier family 22 (organic cation transporter), member 13	0.012
Rasgrp4	RAS guanyl releasing protein 4	0.012
Gm13102	predicted gene 13102	0.012
Klk1b27	kallikrein 1-related peptidase b27	0.012
Rab27a	RAB27A, member RAS oncogene family	0.012
Cd53	CD53 antigen	0.012
Cp	ceruloplasmin	0.012
Tlr7	toll-like receptor 7	0.012
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.012
Mrgpra1	MAS-related GPR, member A1	0.012
Arid5a	AT rich interactive domain 5A (MRF1-like)	0.011
Pkhd1l1	polycystic kidney and hepatic disease 1-like 1	0.011
Osm	oncostatin M	0.011
Clec1b	C-type lectin domain family 1, member b	0.011
Oas3	2'-5' oligoadenylate synthetase 3	0.011
Mc4r	melanocortin 4 receptor	0.011
Rhbg	Rhesus blood group-associated B glycoprotein	0.011
Trem2	triggering receptor expressed on myeloid cells 2	0.011
2210406H18Rik	RIKEN cDNA 2210406H18 gene	0.011
Arhgap4	Rho GTPase activating protein 4	0.011
Timp1	tissue inhibitor of metalloproteinase 1	0.011
Golt1a	golgi transport 1 homolog A (S. cerevisiae)	0.011
Cyp2d34	cytochrome P450, family 2, subfamily d, polypeptide 34	0.011
Tnfsf13b	tumor necrosis factor (ligand) superfamily, member 13b	0.011
Ms4a3	membrane-spanning 4-domains, subfamily A, member 3	0.011
Clec4a3	C-type lectin domain family 4, member a3	0.011
Saa3	serum amyloid A 3	0.011
Oosp1	oocyte secreted protein 1	0.011
Etv6	ets variant gene 6 (TEL oncogene)	0.011
Gm14548	predicted gene 14548	0.011
Nfkbid	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta	0.011
Haao	3-hydroxyanthranilate 3,4-dioxygenase	0.011
A630033H20Rik	RIKEN cDNA A630033H20 gene	0.011
Tlr5	toll-like receptor 5	0.011	Mouse
Pqlc3	PQ loop repeat containing	0.011
Csf1r	colony stimulating factor 1 receptor	0.011
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.011
Eppk1	epiplakin 1	0.011
Ttc36	tetratricopeptide repeat domain 36	0.011
BC089597	cDNA sequence BC089597	0.011
Hsd17b13	hydroxysteroid (17-beta) dehydrogenase 13	0.011
Plekhg6	pleckstrin homology domain containing, family G (with RhoGef domain) member 6	0.010
Slamf6	SLAM family member 6	0.010
Cml3	camello-like 3	0.010
Mia2	melanoma inhibitory activity 2	0.010
Mettl7b	methyltransferase like 7B	0.010
Irf6	interferon regulatory factor 6	0.010
Gm6484	predicted gene 6484	0.010
Alox5	arachidonate 5-lipoxygenase	0.010
BC005685	cDNA sequence BC005685	0.010
Amd2	S-adenosylmethionine decarboxylase 2	0.010
Clec9a	C-type lectin domain family 9, member a	0.010
Gm5045	predicted gene 5045	0.010
Apoe	apolipoprotein E	0.010
Lpcat2	lysophosphatidylcholine acyltransferase 2	0.010
Ffar3	free fatty acid receptor 3	0.010