IMP

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Mus musculus

27 genes annotated in mouse

Multi-species View

positive regulation of protein ubiquitination

GO:0031398

Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin groups to a protein.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of protein ubiquitination"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of protein ubiquitination" (in gray)

Name	Description	Probability	Func Analog Organism
Ctnnb1	catenin (cadherin associated protein), beta 1	0.967
Axin1	axin 1	0.836
Gsk3b	glycogen synthase kinase 3 beta	0.756
Trp53	transformation related protein 53	0.681
Mdm2	transformed mouse 3T3 cell double minute 2	0.606
Tlr4	toll-like receptor 4	0.585
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.357
Atf4	activating transcription factor 4	0.347
Smad2	MAD homolog 2 (Drosophila)	0.320
ND6	NADH dehydrogenase subunit 6	0.277
Myd88	myeloid differentiation primary response gene 88	0.263
Apc	adenomatosis polyposis coli	0.226
Smad7	MAD homolog 7 (Drosophila)	0.175	Human
Arrb1	arrestin, beta 1	0.139
Hipk1	homeodomain interacting protein kinase 1	0.135
Cd44	CD44 antigen	0.130
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.109
Src	Rous sarcoma oncogene	0.104
Tbx3	T-box 3	0.096
Manf	mesencephalic astrocyte-derived neurotrophic factor	0.093
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.085
Rnf111	ring finger 111	0.080
Lrp5	low density lipoprotein receptor-related protein 5	0.075	Mouse
Mta2	metastasis-associated gene family, member 2	0.074
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.065
Fgfr1	fibroblast growth factor receptor 1	0.064	Mouse
Vangl2	vang-like 2 (van gogh, Drosophila)	0.056
Ppp1ca	protein phosphatase 1, catalytic subunit, alpha isoform	0.055
Fgfr3	fibroblast growth factor receptor 3	0.054
Fgfr2	fibroblast growth factor receptor 2	0.049	Mouse
Kif22	kinesin family member 22	0.048
Eif2c1	eukaryotic translation initiation factor 2C, 1	0.046
Cd33	CD33 antigen	0.046
Bcar1	breast cancer anti-estrogen resistance 1	0.045
Foxm1	forkhead box M1	0.045
Lrp6	low density lipoprotein receptor-related protein 6	0.044	Mouse
Tlr2	toll-like receptor 2	0.042
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.042
E2f1	E2F transcription factor 1	0.042
Pparg	peroxisome proliferator activated receptor gamma	0.042
Traf3	TNF receptor-associated factor 3	0.042
Nbn	nibrin	0.037
Stk4	serine/threonine kinase 4	0.036
Bmp5	bone morphogenetic protein 5	0.036
Mdm4	transformed mouse 3T3 cell double minute 4	0.036
Daxx	Fas death domain-associated protein	0.035
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.035
Bub1b	budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)	0.035
Aurka	aurora kinase A	0.035
Ooep	oocyte expressed protein homolog (dog)	0.035
Brca2	breast cancer 2	0.034
Ccnb1	cyclin B1	0.034
Btg1	B-cell translocation gene 1, anti-proliferative	0.034
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.034
Lyz2	lysozyme 2	0.033
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.032
Dvl2	dishevelled 2, dsh homolog (Drosophila)	0.032
Smad6	MAD homolog 6 (Drosophila)	0.031
Mbd3	methyl-CpG binding domain protein 3	0.031
Cdca8	cell division cycle associated 8	0.031
Hras1	Harvey rat sarcoma virus oncogene 1	0.031
Sertad2	SERTA domain containing 2	0.030
Nsfl1c	NSFL1 (p97) cofactor (p47)	0.030
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.029
Ube2c	ubiquitin-conjugating enzyme E2C	0.029
Hsp90b1	heat shock protein 90, beta (Grp94), member 1	0.028
Phf1	PHD finger protein 1	0.027
Traf6	TNF receptor-associated factor 6	0.027
Atxn3	ataxin 3	0.027
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.027
Axin2	axin2	0.027	Mouse
Itga3	integrin alpha 3	0.026
Mavs	mitochondrial antiviral signaling protein	0.026
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.026
Becn1	beclin 1, autophagy related	0.026
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.026
Htt	huntingtin	0.025
Smurf1	SMAD specific E3 ubiquitin protein ligase 1	0.025
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.025
Eif1b	eukaryotic translation initiation factor 1B	0.025
Csnk2a1	casein kinase 2, alpha 1 polypeptide	0.025
Wls	wntless homolog (Drosophila)	0.024
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.024
Mefv	Mediterranean fever	0.024
Pten	phosphatase and tensin homolog	0.024
Diablo	diablo homolog (Drosophila)	0.024
Asap1	ArfGAP with SH# domain, ankyrin repeat and PH domain1	0.024
Mocs1	molybdenum cofactor synthesis 1	0.023
Dnajc3	DnaJ (Hsp40) homolog, subfamily C, member 3	0.023
Atr	ataxia telangiectasia and Rad3 related	0.023
Sh3gl3	SH3-domain GRB2-like 3	0.022
Kif20a	kinesin family member 20A	0.022
Apoe	apolipoprotein E	0.022
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.022
Rb1	retinoblastoma 1	0.022
Atm	ataxia telangiectasia mutated homolog (human)	0.022
Hcst	hematopoietic cell signal transducer	0.021
Mcl1	myeloid cell leukemia sequence 1	0.021
Cblb	Casitas B-lineage lymphoma b	0.021
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.021
Pax2	paired box gene 2	0.021
Hspa8	heat shock protein 8	0.021
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.021
Shh	sonic hedgehog	0.021
Gli2	GLI-Kruppel family member GLI2	0.021
Smad3	MAD homolog 3 (Drosophila)	0.020
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.020
Cbfb	core binding factor beta	0.020
Pofut1	protein O-fucosyltransferase 1	0.020
Xbp1	X-box binding protein 1	0.020
Dll1	delta-like 1 (Drosophila)	0.020
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.019
Akt1	thymoma viral proto-oncogene 1	0.019
Hccs	holocytochrome c synthetase	0.019
Fgfrl1	fibroblast growth factor receptor-like 1	0.019
Nfam1	Nfat activating molecule with ITAM motif 1	0.019
Lig4	ligase IV, DNA, ATP-dependent	0.019
Npr2	natriuretic peptide receptor 2	0.018
Il17ra	interleukin 17 receptor A	0.018
Notch2	Notch gene homolog 2 (Drosophila)	0.018
Siglece	sialic acid binding Ig-like lectin E	0.018
Lyst	lysosomal trafficking regulator	0.018
Adrb1	adrenergic receptor, beta 1	0.018
Bcl6	B-cell leukemia/lymphoma 6	0.018
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.017
Il1f9	interleukin 1 family, member 9	0.017
Rnf19b	ring finger protein 19B	0.017
Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.017
Dsg4	desmoglein 4	0.017
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.017
Id2	inhibitor of DNA binding 2	0.017
Sykb	spleen tyrosine kinase	0.017
Map3k2	mitogen-activated protein kinase kinase kinase 2	0.017
Idua	iduronidase, alpha-L-	0.017
Banf1	barrier to autointegration factor 1	0.016
Pkd1	polycystic kidney disease 1 homolog	0.016
Rfwd2	ring finger and WD repeat domain 2	0.016
Pick1	protein interacting with C kinase 1	0.016
Ywhaq	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.016
Samd4b	sterile alpha motif domain containing 4B	0.016
Ccnb2	cyclin B2	0.016
Sox13	SRY-box containing gene 13	0.016
Ifngr1	interferon gamma receptor 1	0.016
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.016
Phospho1	phosphatase, orphan 1	0.016
Ddx5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.016
Il1b	interleukin 1 beta	0.016
Hoxa5	homeobox A5	0.016
Notch1	Notch gene homolog 1 (Drosophila)	0.016
Cdk1	cyclin-dependent kinase 1	0.016
Rhbdf2	rhomboid 5 homolog 2 (Drosophila)	0.015
Capzb	capping protein (actin filament) muscle Z-line, beta	0.015
Unc93b1	unc-93 homolog B1 (C. elegans)	0.015
Mfn2	mitofusin 2	0.015
Erh	enhancer of rudimentary homolog (Drosophila)	0.015
Ifnar1	interferon (alpha and beta) receptor 1	0.015
Grb7	growth factor receptor bound protein 7	0.015
Socs3	suppressor of cytokine signaling 3	0.015
Gtse1	G two S phase expressed protein 1	0.015
Kiss1	KiSS-1 metastasis-suppressor	0.015
Rangrf	RAN guanine nucleotide release factor	0.014
Bap1	Brca1 associated protein 1	0.014
Supv3l1	suppressor of var1, 3-like 1 (S. cerevisiae)	0.014
Prkcb	protein kinase C, beta	0.014
Spry2	sprouty homolog 2 (Drosophila)	0.014
Cdh1	cadherin 1	0.014
Mapre3	microtubule-associated protein, RP/EB family, member 3	0.014
Ffar3	free fatty acid receptor 3	0.014
Zfp238	zinc finger protein 238	0.014
Fbxo43	F-box protein 43	0.014
Gphn	gephyrin	0.014
Lfng	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.014
Magea5	melanoma antigen, family A, 5	0.014	Human
Foxa2	forkhead box A2	0.014
Pgrmc1	progesterone receptor membrane component 1	0.014
Ubc	ubiquitin C	0.014
Ptch1	patched homolog 1	0.014
P2ry13	purinergic receptor P2Y, G-protein coupled 13	0.014
Cd300lb	CD300 antigen like family member B	0.014
Trem3	triggering receptor expressed on myeloid cells 3	0.014
Trem1	triggering receptor expressed on myeloid cells 1	0.014
Adrb3	adrenergic receptor, beta 3	0.014
Rad51	RAD51 homolog (S. cerevisiae)	0.014
Cd14	CD14 antigen	0.014
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.014
Spag7	sperm associated antigen 7	0.014
Sorbs3	sorbin and SH3 domain containing 3	0.014
Dnm1l	dynamin 1-like	0.013
Patz1	POZ (BTB) and AT hook containing zinc finger 1	0.013
Pycard	PYD and CARD domain containing	0.013
Fbxo5	F-box protein 5	0.013
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.013
Pilrb1	paired immunoglobin-like type 2 receptor beta 1	0.013
Zbtb7b	zinc finger and BTB domain containing 7B	0.013
Ccne1	cyclin E1	0.013
Klf5	Kruppel-like factor 5	0.013
Duox2	dual oxidase 2	0.013
Taf7l	TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.013
Mrps7	mitchondrial ribosomal protein S7	0.013
Ctnnd1	catenin (cadherin associated protein), delta 1	0.013
Il6st	interleukin 6 signal transducer	0.013
Ube2d2	ubiquitin-conjugating enzyme E2D 2	0.013
Gpd2	glycerol phosphate dehydrogenase 2, mitochondrial	0.013
Zfpm1	zinc finger protein, multitype 1	0.013
Ppp1r8	protein phosphatase 1, regulatory (inhibitor) subunit 8	0.013
Sphk2	sphingosine kinase 2	0.013
Gadd45a	growth arrest and DNA-damage-inducible 45 alpha	0.013
Ccna2	cyclin A2	0.012
Stam2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	0.012
Tbcb	tubulin folding cofactor B	0.012
Camk2g	calcium/calmodulin-dependent protein kinase II gamma	0.012
Fkbp4	FK506 binding protein 4	0.012
Traf2	TNF receptor-associated factor 2	0.012
Mex3d	mex3 homolog D (C. elegans)	0.012
Lama5	laminin, alpha 5	0.012
Ube4b	ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)	0.012
Bmp4	bone morphogenetic protein 4	0.012
Cops8	COP9 (constitutive photomorphogenic) homolog, subunit 8 (Arabidopsis thaliana)	0.012
Actr2	ARP2 actin-related protein 2 homolog (yeast)	0.012
Pfn2	profilin 2	0.012
Fyn	Fyn proto-oncogene	0.012
Pkdcc	protein kinase domain containing, cytoplasmic	0.012
Mafb	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.012
Pdia4	protein disulfide isomerase associated 4	0.012
Nedd4	neural precursor cell expressed, developmentally down-regulated 4	0.012
Ccng2	cyclin G2	0.012
Rbbp7	retinoblastoma binding protein 7	0.012
Ccnf	cyclin F	0.012
Prkce	protein kinase C, epsilon	0.012
Tgif1	TGFB-induced factor homeobox 1	0.012
Ly96	lymphocyte antigen 96	0.012
Taf12	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.012
Egfr	epidermal growth factor receptor	0.012
Vps37c	vacuolar protein sorting 37C (yeast)	0.012
Ap2a1	adaptor protein complex AP-2, alpha 1 subunit	0.011
Sox11	SRY-box containing gene 11	0.011
Dusp6	dual specificity phosphatase 6	0.011
Gata3	GATA binding protein 3	0.011
Sox2	SRY-box containing gene 2	0.011
Spag5	sperm associated antigen 5	0.011
Aurkb	aurora kinase B	0.011
Plin1	perilipin 1	0.011
Mapk8	mitogen-activated protein kinase 8	0.011
Smad4	MAD homolog 4 (Drosophila)	0.011
Adam8	a disintegrin and metallopeptidase domain 8	0.011
Gsk3a	glycogen synthase kinase 3 alpha	0.011
Enoph1	enolase-phosphatase 1	0.011
Sav1	salvador homolog 1 (Drosophila)	0.011
Stk40	serine/threonine kinase 40	0.011	Mouse
Sntg2	syntrophin, gamma 2	0.011
Tert	telomerase reverse transcriptase	0.011
Nr6a1	nuclear receptor subfamily 6, group A, member 1	0.011
Hdac6	histone deacetylase 6	0.011
Mta1	metastasis associated 1	0.011	Human
Tgfbr1	transforming growth factor, beta receptor I	0.011
Zfp281	zinc finger protein 281	0.011
Mrps18a	mitochondrial ribosomal protein S18A	0.011
Rhcg	Rhesus blood group-associated C glycoprotein	0.011
Arrb2	arrestin, beta 2	0.011	Human
1700040I03Rik	RIKEN cDNA 1700040I03 gene	0.011
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.011
Pop7	processing of precursor 7, ribonuclease P family, (S. cerevisiae)	0.011
Jag2	jagged 2	0.011
Mov10	Moloney leukemia virus 10	0.011
Ptpre	protein tyrosine phosphatase, receptor type, E	0.010
Mink1	misshapen-like kinase 1 (zebrafish)	0.010
Tcf21	transcription factor 21	0.010
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.010
Commd6	COMM domain containing 6	0.010
Pbx1	pre B-cell leukemia transcription factor 1	0.010
Rangap1	RAN GTPase activating protein 1	0.010
Rac1	RAS-related C3 botulinum substrate 1	0.010
Arrdc1	arrestin domain containing 1	0.010
Mrgpra2a	MAS-related GPR, member A2A	0.010
4632428N05Rik	RIKEN cDNA 4632428N05 gene	0.010
Klf10	Kruppel-like factor 10	0.010
Apbb1ip	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	0.010
Med1	mediator complex subunit 1	0.010
Gm16517	predicted gene, Gm16517	0.010
Eno1	enolase 1, alpha non-neuron	0.010
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.010
Ncapd2	non-SMC condensin I complex, subunit D2	0.010
Irak4	interleukin-1 receptor-associated kinase 4	0.010
Plekho2	pleckstrin homology domain containing, family O member 2	0.010