The network for 'cellular response to abiotic stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular response to abiotic stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus.

Mus musculus
Name Description Probability Func Analog Organism
Trp53 transformation related protein 53 0.995
Pten phosphatase and tensin homolog 0.977
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.844
Mapk14 mitogen-activated protein kinase 14 0.812
Pax6 paired box gene 6 0.779
Rho rhodopsin 0.729
Col1a1 collagen, type I, alpha 1 0.715
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.701
Kit kit oncogene 0.685
Rb1 retinoblastoma 1 0.673
Fas Fas (TNF receptor superfamily member 6) 0.622
Tgfb1 transforming growth factor, beta 1 0.621
Runx2 runt related transcription factor 2 0.604
Bcl2 B-cell leukemia/lymphoma 2 0.595
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.592
Rac1 RAS-related C3 botulinum substrate 1 0.550
Sp1 trans-acting transcription factor 1 0.491
Brca1 breast cancer 1 0.488
Gdnf glial cell line derived neurotrophic factor 0.481
Igh immunoglobulin heavy chain complex 0.480
Grb10 growth factor receptor bound protein 10 0.479
Slc12a1 solute carrier family 12, member 1 0.479
Tlr4 toll-like receptor 4 0.450
Thrb thyroid hormone receptor beta 0.443
Fgfr2 fibroblast growth factor receptor 2 0.416
Brca2 breast cancer 2 0.413
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.403
Slc12a2 solute carrier family 12, member 2 0.400
Mef2d myocyte enhancer factor 2D 0.400
Stat3 signal transducer and activator of transcription 3 0.388
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.382
Smad4 MAD homolog 4 (Drosophila) 0.371
Ptgs2 prostaglandin-endoperoxide synthase 2 0.353
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.353
Ctnnb1 catenin (cadherin associated protein), beta 1 0.345
Dicer1 Dicer1, Dcr-1 homolog (Drosophila) 0.341
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.340
Apc adenomatosis polyposis coli 0.328
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.326
Nos3 nitric oxide synthase 3, endothelial cell 0.323
Nf1 neurofibromatosis 1 0.315
Kiss1 KiSS-1 metastasis-suppressor 0.299
Ren1 renin 1 structural 0.298
Pkd1 polycystic kidney disease 1 homolog 0.286
Gja1 gap junction protein, alpha 1 0.277
Mmp9 matrix metallopeptidase 9 0.276
Sfrp2 secreted frizzled-related protein 2 0.268
Ryr2 ryanodine receptor 2, cardiac 0.266
Cav1 caveolin 1, caveolae protein 0.257
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.255
Plxnd1 plexin D1 0.251
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.235
Meox2 mesenchyme homeobox 2 0.232
Tnf tumor necrosis factor 0.226
Slc4a7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.224
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.220
Neurod1 neurogenic differentiation 1 0.217
Rbl1 retinoblastoma-like 1 (p107) 0.216
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.212
Thra thyroid hormone receptor alpha 0.207
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.205
Kitl kit ligand 0.199
Zeb1 zinc finger E-box binding homeobox 1 0.198
Srrm4 serine/arginine repetitive matrix 4 0.196
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.196
Nos2 nitric oxide synthase 2, inducible 0.191
Hand1 heart and neural crest derivatives expressed transcript 1 0.191
Crx cone-rod homeobox containing gene 0.190
Insr insulin receptor 0.190
Stat5b signal transducer and activator of transcription 5B 0.187
Cyld cylindromatosis (turban tumor syndrome) 0.185
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.185
Atf2 activating transcription factor 2 0.181
Ep300 E1A binding protein p300 0.178
Foxp3 forkhead box P3 0.176
Homer1 homer homolog 1 (Drosophila) 0.176
Stat5a signal transducer and activator of transcription 5A 0.175
Col6a2 collagen, type VI, alpha 2 0.174
Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 0.174
Notch2 Notch gene homolog 2 (Drosophila) 0.172
Fbn1 fibrillin 1 0.172
Foxg1 forkhead box G1 0.171
Mapk8 mitogen-activated protein kinase 8 0.170
Cbl Casitas B-lineage lymphoma 0.169
Kl klotho 0.169
Pbx1 pre B-cell leukemia transcription factor 1 0.167
Gucy1b3 guanylate cyclase 1, soluble, beta 3 0.165
Neurod4 neurogenic differentiation 4 0.165
She src homology 2 domain-containing transforming protein E 0.165
Birc3 baculoviral IAP repeat-containing 3 0.164
Nfe2l2 nuclear factor, erythroid derived 2, like 2 0.163
Pax2 paired box gene 2 0.161
Nr2e1 nuclear receptor subfamily 2, group E, member 1 0.158
Ghr growth hormone receptor 0.156
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.156
Bax BCL2-associated X protein 0.155
Igf1r insulin-like growth factor I receptor 0.155
Fgfr1 fibroblast growth factor receptor 1 0.151
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.149
Lep leptin 0.143
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.176
mpk-1 Protein MPK-1 0.136
let-60 Protein LET-60 0.114
pmk-1 Protein PMK-1 0.106
cnd-1 Protein CND-1 0.099
pry-1 Protein PRY-1 0.082
rskn-2 Protein RSKN-2 0.078
mat-3 Protein MAT-3 0.076
prp-3 Protein PRP-3 0.075
daz-1 Protein DAZ-1 0.074
rpl-11.1 Protein RPL-11.1 0.073
egl-46 Protein EGL-46 0.073
kin-18 Protein KIN-18 0.072
sop-3 Protein SOP-3 0.069
akt-2 Protein AKT-2 0.067
mel-28 Protein MEL-28 0.059
ztf-15 Protein ZTF-15 0.058
K02C4.3 Protein K02C4.3 0.058
egl-1 Protein EGL-1 0.057
figl-1 Protein FIGL-1 0.055
tra-1 Protein TRA-1 0.054
mls-2 Protein MLS-2 0.053
F09F7.5 Protein F09F7.5 0.053
dlk-1 Protein DLK-1 0.053
zfp-3 Protein ZFP-3 0.052
tbg-1 Protein TBG-1 0.050
CELE_F54D5.5 Protein F54D5.5 0.050
gld-1 Protein GLD-1 0.050
F59E12.9 Protein F59E12.9 0.049
gpr-1 Protein GPR-1 0.049
M151.7 Protein M151.7 0.048
xbx-6 Protein XBX-6 0.047
F21A10.2 Protein F21A10.2 0.046
unc-14 Protein UNC-14 0.046
CELE_C23G10.8 Protein C23G10.8 0.046
sdz-4 Protein SDZ-4 0.046
goa-1 Protein GOA-1 0.045
F22D3.2 Protein F22D3.2 0.045
Y50D7A.8 Protein Y50D7A.8 0.045
CELE_M03A8.3 Protein M03A8.3 0.044
nhr-34 Protein NHR-34 0.044
cdc-25.1 Protein CDC-25.1 0.044
nhr-2 Protein NHR-2 0.044
bbs-2 Protein BBS-2 0.043
C09F5.1 Protein C09F5.1 0.043
daf-16 Protein DAF-16 0.043
osm-6 Protein OSM-6 0.043
zag-1 Protein ZAG-1 0.042
vab-3 Protein VAB-3 0.042
unc-130 Protein UNC-130 0.042
bar-1 Protein BAR-1 0.042
hmg-1.1 Protein HMG-1.1 0.042
gon-4 Protein GON-4 0.041
rbc-1 Protein RBC-1 0.041
sek-1 Protein SEK-1 0.041
egl-5 Protein EGL-5 0.041
flt-1 Protein FLT-1 0.041
sox-3 Protein SOX-3 0.041
nhr-142 Protein NHR-142 0.040
stam-1 Protein STAM-1 0.040
F19B6.1 Protein F19B6.1 0.040
lin-45 Protein LIN-45 0.040
smc-3 Protein SMC-3 0.040
retr-1 Protein RETR-1 0.040
fog-2 Protein FOG-2 0.040
C28A5.1 Protein C28A5.1 0.039
F02E8.4 Protein F02E8.4 0.039
rab-11.1 Protein RAB-11.1 0.039
par-5 Protein PAR-5 0.039
unc-54 Protein UNC-54 0.039
let-756 Protein LET-756 0.039
F09D1.1 Protein F09D1.1 0.039
Y102A11A.3 Protein Y102A11A.3 0.039
mkk-4 Protein MKK-4 0.038
gla-3 Protein GLA-3 0.038
cmd-1 Protein CMD-1 0.037
plc-1 Protein PLC-1 0.037
C32D5.8 Protein C32D5.8 0.037
pmk-3 Protein PMK-3 0.037
pop-1 Protein POP-1 0.037
mab-3 Protein MAB-3 0.037
htz-1 Protein HTZ-1 0.037
cutl-13 Protein CUTL-13 0.036
gei-4 Protein GEI-4 0.036
plc-3 Protein PLC-3 0.036
ceh-44 Protein CEH-44 0.036
mlk-1 Protein MLK-1 0.035
mes-3 Protein MES-3 0.035
sun-1 Protein SUN-1 0.035
F40G9.6 Protein F40G9.6 0.035
gtl-1 Protein GTL-1 0.035
lin-59 Protein LIN-59 0.035
CELE_R17.2 Protein R17.2 0.034
ztf-23 Protein ZTF-23 0.034
rpn-10 Protein RPN-10 0.034
C34D10.2 Protein C34D10.2 0.034
eor-2 Protein EOR-2 0.034
gpb-1 Protein GPB-1 0.034
unc-104 Protein UNC-104 0.034
sos-1 Protein SOS-1 0.034
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Danio rerio
Name Description Probability Func Analog Organism
gnat2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.138
opn4a opsin 4a (melanopsin) 0.120
prox1 prospero-related homeobox gene 1 0.091
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.080
cdh1 cadherin 1, epithelial 0.044
per2 period homolog 2 (Drosophila) 0.035
ptger2a prostaglandin E receptor 2a (subtype EP2) 0.032
rx1 retinal homeobox gene 1 0.030
gcm2 glial cells missing homolog 2 (Drosophila) 0.029
jag1b jagged 1b 0.029
celsr3 cadherin, EGF LAG seven-pass G-type receptor 3 0.027
opn4l opsin 4, like 0.026
ptgs1 prostaglandin-endoperoxide synthase 1 0.025
rho rhodopsin 0.023
per3 period homolog 3 (Drosophila) 0.023
opn1sw1 opsin 1 (cone pigments), short-wave-sensitive 1 0.022
runx3 runt-related transcription factor 3 0.022
pdlim1 PDZ and LIM domain 1 (elfin) 0.022
pitx3 paired-like homeodomain transcription factor 3 0.022
vsx1 visual system homeobox 1 homolog, chx10-like 0.021
bcl2l1 bcl2-like 1 0.020
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.020
LOC100331502 melanopsin-B-like 0.018
mcl1a myeloid cell leukemia sequence 1a 0.018
nrg2a neuregulin 2a 0.018
mmp2 matrix metalloproteinase 2 0.017
dync1h1 dynein, cytoplasmic 1, heavy chain 1 0.017
bbc3 BCL2 binding component 3 0.017
socs3a suppressor of cytokine signaling 3a 0.016
opn1lw1 opsin 1 (cone pigments), long-wave-sensitive, 1 0.016
atp1a1a.2 ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide 0.016
wnt11r wingless-type MMTV integration site family, member 11, related 0.016
grk7a G-protein-coupled receptor kinase 7a 0.016
otx5 orthodenticle homolog 5 0.016
gnat1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 0.015
atp1a1a.3 ATPase, Na+/K+ transporting, alpha 1a.3 polypeptide 0.015
crybb1 crystallin, beta B1 0.015
baxa bcl2-associated X protein, a 0.015
mapk1 mitogen-activated protein kinase 1 0.014
tpma alpha-tropomyosin 0.013
opn4x1 opsin 4x1 0.013
col1a2 collagen, type I, alpha 2 0.013
opn1sw2 opsin 1 (cone pigments), short-wave-sensitive 2 0.013
itgb1b.1 integrin, beta 1b.1 0.013
gc3 guanylyl cyclase 3 0.012
socs1 suppressor of cytokine signaling 1 0.012
ef1a elongation factor 1-alpha 0.012
gpr126 G protein-coupled receptor 126 0.012
mdm2 transformed 3T3 cell double minute 2 homolog (mouse) 0.012
slc12a2 solute carrier family 12 (potassium/chloride transporters), member 2 0.012
si:dkey-8l13.4 si:dkey-8l13.4 0.012
mipa major intrinsic protein of lens fiber a 0.011
LOC100003330 melanocortin-2 receptor accessory protein 2-like 0.011
ccdc40 coiled-coil domain containing 40 0.011
mapk12 mitogen-activated protein kinase 12 0.010
gli1 GLI-Kruppel family member 1 0.010
cry1a cryptochrome 1a 0.010
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Drosophila melanogaster
Name Description Probability Func Analog Organism
trp transient receptor potential 1.000
inaD inactivation no afterpotential D 0.991
trpl trp-like 0.969
G-salpha60A G protein salpha 60A 0.955
Arr2 Arrestin 2 0.946
ninaE neither inactivation nor afterpotential E 0.933
sxc super sex combs 0.794
rl rolled 0.792
rdgB retinal degeneration B 0.723
Rh6 Rhodopsin 6 0.715
CaMKII Calcium/calmodulin-dependent protein kinase II 0.709
ninaA neither inactivation nor afterpotential A 0.701
CG8486 CG8486 gene product from transcript CG8486-RE 0.646
inaC inactivation no afterpotential C 0.644
p53 CG33336 gene product from transcript CG33336-RB 0.638
Rh3 Rhodopsin 3 0.625
rdgC retinal degeneration C 0.623
Ubqn Ubiquilin 0.618
rdgA retinal degeneration A 0.591
Ric Ras which interacts with Calmodulin 0.513
rpr reaper 0.490
18w 18 wheeler 0.471
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.467
sev sevenless 0.461
ninaC neither inactivation nor afterpotential C 0.460
rad50 CG6339 gene product from transcript CG6339-RD 0.458
Timp Tissue inhibitor of metalloproteases 0.453
Galpha49B G protein alpha49B 0.430
slmb supernumerary limbs 0.424
Gbeta76C G protein beta-subunit 76C 0.398
Cng Cyclic-nucleotide-gated ion channel protein 0.353
CG5524 CG5524 gene product from transcript CG5524-RA 0.351
plx pollux 0.349
hyd hyperplastic discs 0.334
Rh5 Rhodopsin 5 0.333
pain painless 0.328
Hsp27 Heat shock protein 27 0.326
Dredd Death related ced-3/Nedd2-like protein 0.325
norpA no receptor potential A 0.317
CRMP Collapsin Response Mediator Protein 0.301
RecQ5 homolog of RecQ 0.291
Irk3 Inwardly rectifying potassium channel 3 0.287
Ca-beta Ca2+-channel-protein-beta-subunit 0.276
Sin3A CG8815 gene product from transcript CG8815-RC 0.276
chp chaoptic 0.275
Tsp29Fb Tetraspanin 29Fb 0.271
pdfr PDF receptor 0.263
Act5C Actin 5C 0.260
gfA giant fibre A 0.257
Pka-C1 cAMP-dependent protein kinase 1 0.253
tral trailer hitch 0.248
Spf45 CG17540 gene product from transcript CG17540-RB 0.248
Eip63E Ecdysone-induced protein 63E 0.247
lgs legless 0.246
Gyc-89Db Guanylyl cyclase at 89Db 0.245
Spn77Ba Serpin 77Ba 0.243
scny scrawny 0.235
tim timeless 0.230
nbs CG6754 gene product from transcript CG6754-RC 0.219
kay kayak 0.210
mub mushroom-body expressed 0.207
imd immune deficiency 0.206
Arr1 Arrestin 1 0.204
dco discs overgrown 0.198
prc pericardin 0.180
Hcf Host cell factor 0.173
CG4857 CG4857 gene product from transcript CG4857-RD 0.170
CG14686 CG14686 gene product from transcript CG14686-RA 0.168
CG32792 CG32792 gene product from transcript CG32792-RF 0.168
inaF-D CG42563 gene product from transcript CG42563-RB 0.164
boss bride of sevenless 0.164
Rala Ras-related protein 0.163
ppk pickpocket 0.161
unc-13 CG2999 gene product from transcript CG2999-RA 0.161
elav embryonic lethal abnormal vision 0.157
DNApol-eta CG7143 gene product from transcript CG7143-RA 0.157
unc79 CG5237 gene product from transcript CG5237-RB 0.155
Hsp68 Heat shock protein 68 0.154
Mkrn1 Makorin 1 0.153
dpp decapentaplegic 0.152
Myd88 CG2078 gene product from transcript CG2078-RA 0.152
klg klingon 0.151
CG1572 CG1572 gene product from transcript CG1572-RA 0.147
tsh teashirt 0.147
Ilp6 Insulin-like peptide 6 0.145
kibra kibra ortholog 0.141
th thread 0.141
cta concertina 0.137
egr eiger 0.137
CG13704 CG13704 gene product from transcript CG13704-RA 0.136
l(2)gl lethal (2) giant larvae 0.136
CG33289 CG33289 gene product from transcript CG33289-RA 0.133
Tsp42El Tetraspanin 42El 0.132
HLHmdelta E(spl) region transcript mdelta 0.131
Hnf4 Hepatocyte nuclear factor 4 0.131
Kr-h1 Kruppel homolog 1 0.129
Tsp42Eh Tetraspanin 42Eh 0.129
Akt1 CG4006 gene product from transcript CG4006-RA 0.128
Eaat1 Excitatory amino acid transporter 1 0.126
ed echinoid 0.124
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Homo sapiens
Name Description Probability Func Analog Organism
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.999
BRCA1 breast cancer 1, early onset 0.996
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.990
CFLAR CASP8 and FADD-like apoptosis regulator 0.986
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.967
CRYAB crystallin, alpha B 0.967
TP53 tumor protein p53 0.960
HDAC4 histone deacetylase 4 0.958
HSPB1 heat shock 27kDa protein 1 0.949
BCL2L1 BCL2-like 1 0.943
XIAP X-linked inhibitor of apoptosis 0.941
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.929
BCL2 B-cell CLL/lymphoma 2 0.891
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.889
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.889
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.884
MAPK14 mitogen-activated protein kinase 14 0.883
DDB1 damage-specific DNA binding protein 1, 127kDa 0.882
HSPB8 heat shock 22kDa protein 8 0.858
ARRB1 arrestin, beta 1 0.844
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.820
MAPK1 mitogen-activated protein kinase 1 0.789
EP300 E1A binding protein p300 0.776
BTRC beta-transducin repeat containing 0.760
IL1R1 interleukin 1 receptor, type I 0.752
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.733
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.714
CHEK1 CHK1 checkpoint homolog (S. pombe) 0.699
LRRK2 leucine-rich repeat kinase 2 0.687
CDK2 cyclin-dependent kinase 2 0.679
TEK TEK tyrosine kinase, endothelial 0.679
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.611
DUSP1 dual specificity phosphatase 1 0.600
SMAD4 SMAD family member 4 0.586
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.586
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.584
RAD1 RAD1 homolog (S. pombe) 0.580
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.557
FADD Fas (TNFRSF6)-associated via death domain 0.556
IL4R interleukin 4 receptor 0.553
MAP2K4 mitogen-activated protein kinase kinase 4 0.552
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.547
RB1 retinoblastoma 1 0.545
CAB39 calcium binding protein 39 0.526
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.513
KIAA1377 KIAA1377 0.513
NBN nibrin 0.502
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.501
HIST1H2BG histone cluster 1, H2bg 0.492
EGFR epidermal growth factor receptor 0.490
CUL4A cullin 4A 0.478
APAF1 apoptotic peptidase activating factor 1 0.473
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.469
PRKD2 protein kinase D2 0.432
BRCA2 breast cancer 2, early onset 0.428
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.427
TAL1 T-cell acute lymphocytic leukemia 1 0.413
CCNE1 cyclin E1 0.401
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.401
NMI N-myc (and STAT) interactor 0.398
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.393
TRAF5 TNF receptor-associated factor 5 0.383
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like 0.377
IRS1 insulin receptor substrate 1 0.376
H2AFX H2A histone family, member X 0.375
PARP1 poly (ADP-ribose) polymerase 1 0.369
ATM ataxia telangiectasia mutated 0.366
STAT5A signal transducer and activator of transcription 5A 0.361
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.361
NCF1 neutrophil cytosolic factor 1 0.358
ARRB2 arrestin, beta 2 0.352
ACTB actin, beta 0.350
CRYGC crystallin, gamma C 0.335
BMPR1A bone morphogenetic protein receptor, type IA 0.335
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.334
MAP3K1 mitogen-activated protein kinase kinase kinase 1 0.332
SOCS3 suppressor of cytokine signaling 3 0.328
CAV1 caveolin 1, caveolae protein, 22kDa 0.328
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.320
SIRT1 sirtuin 1 0.313
PLAU plasminogen activator, urokinase 0.307
MYD88 myeloid differentiation primary response gene (88) 0.296
UHRF2 ubiquitin-like with PHD and ring finger domains 2 0.292
IRAK2 interleukin-1 receptor-associated kinase 2 0.290
ARHGAP1 Rho GTPase activating protein 1 0.289
RAB11A RAB11A, member RAS oncogene family 0.285
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.278
KAT2B K(lysine) acetyltransferase 2B 0.277
SCNN1B sodium channel, nonvoltage-gated 1, beta 0.276
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.274
HIPK2 homeodomain interacting protein kinase 2 0.273
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 0.268
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.267
NCF2 neutrophil cytosolic factor 2 0.263
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 0.261
ATF2 activating transcription factor 2 0.259
FGA fibrinogen alpha chain 0.252
STAT2 signal transducer and activator of transcription 2, 113kDa 0.252
ING2 inhibitor of growth family, member 2 0.252
SFN stratifin 0.251
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Rattus norvegicus
Name Description Probability Func Analog Organism
Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 0.398
Igf2 insulin-like growth factor 2 0.391
Trhr thyrotropin releasing hormone receptor 0.262
Gja1 gap junction protein, alpha 1 0.242
Col1a2 collagen, type I, alpha 2 0.240
Bdkrb2 bradykinin receptor B2 0.237
Drd1a dopamine receptor D1A 0.236
Cav1 caveolin 1, caveolae protein 0.222
Tgfb1 transforming growth factor, beta 1 0.216
Col1a1 collagen, type I, alpha 1 0.206
Actb actin, beta 0.194
LOC100362824 caveolin 2-like 0.188
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.174
Flt1 FMS-related tyrosine kinase 1 0.172
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.172
Tbxa2r thromboxane A2 receptor 0.159
Slc5a5 solute carrier family 5 (sodium iodide symporter), member 5 0.159
Jak1 Janus kinase 1 0.151
Kcna6 potassium voltage gated channel, shaker related subfamily, member 6 0.144
Acta2 smooth muscle alpha-actin 0.142
Nkx2-1 NK2 homeobox 1 0.138
Sftpa1 surfactant protein A1 0.138
Chrna2 cholinergic receptor, nicotinic, alpha 2 (neuronal) 0.138
Lepr leptin receptor 0.138
Ahsg alpha-2-HS-glycoprotein 0.134
Adrb1 adrenergic, beta-1-, receptor 0.132
Sparc secreted protein, acidic, cysteine-rich (osteonectin) 0.132
Atp1b2 ATPase, Na+/K+ transporting, beta 2 polypeptide 0.131
Rab1b RAB1B, member RAS oncogene family 0.122
Igfals insulin-like growth factor binding protein, acid labile subunit 0.122
Rara retinoic acid receptor, alpha 0.121
Clcnkb chloride channel Kb 0.120
Pbsn probasin 0.114
Prdm2 PR domain containing 2, with ZNF domain 0.114
Ptgfr prostaglandin F receptor 0.110
Slc7a2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 0.110
Slc6a1 solute carrier family 6 (neurotransmitter transporter, GABA), member 1 0.108
Nr4a3 nuclear receptor subfamily 4, group A, member 3 0.107
Slc12a1 solute carrier family 12 (sodium/potassium/chloride transporters), member 1 0.107
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.106
Nkx6-1 NK6 homeobox 1 0.105
Begain brain-enriched guanylate kinase-associated 0.104
Col8a1 collagen, type VIII, alpha 1 0.100
Fgfr1 Fibroblast growth factor receptor 1 0.098
Prkca protein kinase C, alpha 0.098
Mylk2 myosin light chain kinase 2 0.097
Sycn syncollin 0.096
Bcan brevican 0.095
Tcp11 t-complex protein 11 0.095
Slc14a2 solute carrier family 14 (urea transporter), member 2 0.095
Npffr2 neuropeptide FF receptor 2 0.094
Il6st interleukin 6 signal transducer 0.093
Elovl5 ELOVL family member 5, elongation of long chain fatty acids (yeast) 0.092
Phkg1 phosphorylase kinase, gamma 1 0.092
Map3k3 mitogen activated protein kinase kinase kinase 3 0.092
Mprip myosin phosphatase Rho interacting protein 0.091
Nos3 nitric oxide synthase 3, endothelial cell 0.089
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.085
Cd40lg CD40 ligand 0.084
Adam17 ADAM metallopeptidase domain 17 0.084
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.084
Eef2 eukaryotic translation elongation factor 2 0.082
Ppard peroxisome proliferator-activated receptor delta 0.082
Elf1 E74-like factor 1 0.081
Mapk3 mitogen activated protein kinase 3 0.081
Col10a1 collagen, type X, alpha 1 0.080
Scarb1 scavenger receptor class B, member 1 0.080
Slc6a11 solute carrier family 6 (neurotransmitter transporter, GABA), member 11 0.079
Calcrl calcitonin receptor-like 0.078
Kcnk3 potassium channel, subfamily K, member 3 0.077
Tcf21 transcription factor 21 0.077
Ccr5 chemokine (C-C motif) receptor 5 0.076
Col3a1 collagen, type III, alpha 1 0.075
Col4a1 collagen, type IV, alpha 1 0.075
Shox2 short stature homeobox 2 0.074
Slc9a5 solute carrier family 9 (sodium/hydrogen exchanger), member 5 0.074
Grm7 glutamate receptor, metabotropic 7 0.073
Defb4 defensin beta 4 0.072
Fli1 Friend leukemia virus integration 1 0.072
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.072
Atp7b ATPase, Cu++ transporting, beta polypeptide 0.072
Syt13 synaptotagmin XIII 0.071
Grm5 glutamate receptor, metabotropic 5 0.071
Crhbp corticotropin releasing hormone binding protein 0.071
Gfap glial fibrillary acidic protein 0.070
Nog noggin 0.070
Mapk6 mitogen-activated protein kinase 6 0.070
Hrh4 histamine receptor H4 0.069
Vom2r27 vomeronasal 2 receptor, 27 0.069
Glg1 golgi apparatus protein 1 0.069
Asip agouti signaling protein 0.068
Fgfr2 fibroblast growth factor receptor 2 0.068
Obscn obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 0.067
Ush1c Usher syndrome 1C homolog (human) 0.067
Vom2r32 vomeronasal 2 receptor, 32 0.067
Hspb1 heat shock protein 1 0.067
Cabp1 calcium binding protein 1 0.067
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.066
Mapk9 mitogen-activated protein kinase 9 0.066
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.066
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
PBS2 Pbs2p 0.649
HOG1 Hog1p 0.621
BEM3 Bem3p 0.460
CKA1 Cka1p 0.393
CLA4 Cla4p 0.374
SSK1 Ssk1p 0.331
STE5 Ste5p 0.328
SSK2 Ssk2p 0.300
PSR2 Psr2p 0.274
NBP2 Nbp2p 0.235
AQY2 Aqy2p 0.234
YPL150W hypothetical protein 0.218
RSC9 Rsc9p 0.181
HSP42 Hsp42p 0.181
ZAP1 Zap1p 0.175
CPR1 Cpr1p 0.164
RHO1 Rho1p 0.131
HSP26 Hsp26p 0.130
PSP2 Psp2p 0.128
YKR015C hypothetical protein 0.117
MKK1 Mkk1p 0.117
HAL5 Hal5p 0.112
CYC8 Cyc8p 0.109
MIG2 Mig2p 0.108
MBR1 Mbr1p 0.108
ARP8 Arp8p 0.106
NTH1 Nth1p 0.104
FPS1 Fps1p 0.103
BCK1 Bck1p 0.102
STE7 Ste7p 0.098
SNT1 Snt1p 0.093
PTP3 Ptp3p 0.092
FUS3 Fus3p 0.092
HRK1 Hrk1p 0.090
PTP2 Ptp2p 0.087
HSL1 Hsl1p 0.087
CKA2 Cka2p 0.086
LAP4 Lap4p 0.085
POG1 Pog1p 0.084
TPS2 Tps2p 0.083
TSL1 Tsl1p 0.079
ICL2 Icl2p 0.076
ABP1 Abp1p 0.076
FMP33 Fmp33p 0.075
SSK22 Ssk22p 0.074
YMR315W hypothetical protein 0.074
RSC8 Rsc8p 0.073
GLN3 Gln3p 0.072
EDE1 Ede1p 0.070
PKC1 Pkc1p 0.069
ICY1 Icy1p 0.068
MIG3 Mig3p 0.068
ADY2 Ady2p 0.067
HXT3 Hxt3p 0.067
OPY2 Opy2p 0.067
IES1 Ies1p 0.066
GRR1 Grr1p 0.066
LSP1 Lsp1p 0.065
MSN1 Msn1p 0.065
YKR075C hypothetical protein 0.064
MSC1 Msc1p 0.064
SWI6 Swi6p 0.064
BEM4 Bem4p 0.063
GRX1 Grx1p 0.063
SSP1 Ssp1p 0.063
DIN7 Din7p 0.062
SMP1 Smp1p 0.062
WHI2 Whi2p 0.062
RAD55 Rad55p 0.061
BUD8 Bud8p 0.060
GLE1 Gle1p 0.059
YFL054C hypothetical protein 0.059
INO80 Ino80p 0.058
YNL194C hypothetical protein 0.058
HRP1 Hrp1p 0.058
STE2 Ste2p 0.058
PNC1 Pnc1p 0.057
STE20 Ste20p 0.056
CDC10 Cdc10p 0.056
SDS24 Sds24p 0.054
CDC4 Cdc4p 0.052
TPS1 Tps1p 0.052
PHM8 Phm8p 0.051
RVB1 Rvb1p 0.051
SPG1 Spg1p 0.050
CMD1 Cmd1p 0.050
MYO1 Myo1p 0.050
AIM17 Aim17p 0.050
EAR1 Ear1p 0.049
KSS1 Kss1p 0.049
GIP2 Gip2p 0.049
NTO1 Nto1p 0.049
RCK1 Rck1p 0.049
YJU2 Yju2p 0.049
NUP157 Nup157p 0.048
YKL187C hypothetical protein 0.048
NRG1 Nrg1p 0.048
LCD1 Lcd1p 0.048
DDR48 Ddr48p 0.048
YMR102C hypothetical protein 0.048