The network for 'protein import' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

protein import

The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.

Mus musculus
Name Description Probability Func Analog Organism
Tnf tumor necrosis factor 0.993
Ctnnb1 catenin (cadherin associated protein), beta 1 0.976
Casp1 caspase 1 0.950
Gli3 GLI-Kruppel family member GLI3 0.941
Trp53 transformation related protein 53 0.896
Fgfr1 fibroblast growth factor receptor 1 0.832
Gli2 GLI-Kruppel family member GLI2 0.790
Apc adenomatosis polyposis coli 0.695
Lef1 lymphoid enhancer binding factor 1 0.693
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.665
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.636
Pparg peroxisome proliferator activated receptor gamma 0.633
Fgfr2 fibroblast growth factor receptor 2 0.624
Per2 period homolog 2 (Drosophila) 0.612
Smad3 MAD homolog 3 (Drosophila) 0.597
Thra thyroid hormone receptor alpha 0.593
Ezh2 enhancer of zeste homolog 2 (Drosophila) 0.590
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.583
Ikbkb inhibitor of kappaB kinase beta 0.580
Rarg retinoic acid receptor, gamma 0.558
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.547
Yap1 yes-associated protein 1 0.531
Tbx3 T-box 3 0.528
Pten phosphatase and tensin homolog 0.525
Iqcb1 IQ calmodulin-binding motif containing 1 0.519
Pbx1 pre B-cell leukemia transcription factor 1 0.477
Eya1 eyes absent 1 homolog (Drosophila) 0.470
Zic2 zinc finger protein of the cerebellum 2 0.466
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.463
Tcf21 transcription factor 21 0.447
Meox2 mesenchyme homeobox 2 0.406
Sox2 SRY-box containing gene 2 0.394
Spna1 spectrin alpha 1 0.383
Il1r1 interleukin 1 receptor, type I 0.373
Kpnb1 karyopherin (importin) beta 1 0.373
Drd2 dopamine receptor D2 0.369
Fzd8 frizzled homolog 8 (Drosophila) 0.367
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.355
Bmp4 bone morphogenetic protein 4 0.351
Smad6 MAD homolog 6 (Drosophila) 0.341
Nf2 neurofibromatosis 2 0.338
Pkd1 polycystic kidney disease 1 homolog 0.336
Ghr growth hormone receptor 0.335
Il6st interleukin 6 signal transducer 0.334
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.333
Ikbkg inhibitor of kappaB kinase gamma 0.328
Clock circadian locomotor output cycles kaput 0.324
Bcl2 B-cell leukemia/lymphoma 2 0.323
Gab2 growth factor receptor bound protein 2-associated protein 2 0.322
Per3 period homolog 3 (Drosophila) 0.315
Irs1 insulin receptor substrate 1 0.314
Mknk2 MAP kinase-interacting serine/threonine kinase 2 0.310
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.307
Hspa9 heat shock protein 9 0.302
Apoe apolipoprotein E 0.298
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.295
Nf1 neurofibromatosis 1 0.292
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.291
Rpgrip1l Rpgrip1-like 0.290
Cyld cylindromatosis (turban tumor syndrome) 0.277
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.276
Kpna1 karyopherin (importin) alpha 1 0.273
Nkx2-3 NK2 transcription factor related, locus 3 (Drosophila) 0.263
Hbb-b1 hemoglobin, beta adult major chain 0.254
Hoxd13 homeobox D13 0.254
Ahr aryl-hydrocarbon receptor 0.248
Fzd2 frizzled homolog 2 (Drosophila) 0.247
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.241
Iigp1 interferon inducible GTPase 1 0.239
Eda ectodysplasin-A 0.236
Stat3 signal transducer and activator of transcription 3 0.233
Ltbp4 latent transforming growth factor beta binding protein 4 0.229
Lck lymphocyte protein tyrosine kinase 0.229
Vegfa vascular endothelial growth factor A 0.226
Fgf9 fibroblast growth factor 9 0.224
Per1 period homolog 1 (Drosophila) 0.223
Sfrp2 secreted frizzled-related protein 2 0.223
Wnt5a wingless-related MMTV integration site 5A 0.219
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.216
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.215
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.213
Vdr vitamin D receptor 0.212
Pnpla2 patatin-like phospholipase domain containing 2 0.206
Ar androgen receptor 0.205
Cry2 cryptochrome 2 (photolyase-like) 0.204
Nog noggin 0.203
Shc3 src homology 2 domain-containing transforming protein C3 0.201
Cbl Casitas B-lineage lymphoma 0.200
Hspa4 heat shock protein 4 0.199
Ncoa3 nuclear receptor coactivator 3 0.199
Sim1 single-minded homolog 1 (Drosophila) 0.198
Smo smoothened homolog (Drosophila) 0.197
Axin1 axin 1 0.193
Men1 multiple endocrine neoplasia 1 0.193
Mapk8 mitogen-activated protein kinase 8 0.192
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.190
Pax8 paired box gene 8 0.189
Grb7 growth factor receptor bound protein 7 0.188
Mapk1 mitogen-activated protein kinase 1 0.184
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.182
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
pqn-59 Protein PQN-59 0.158
pry-1 Protein PRY-1 0.070
npp-7 Protein NPP-7 0.065
rpn-1 Protein RPN-1 0.064
egl-18 Protein EGL-18 0.062
mpk-1 Protein MPK-1 0.060
sma-6 Protein SMA-6 0.045
C36E8.1 Protein C36E8.1 0.034
plc-3 Protein PLC-3 0.031
lin-36 Protein LIN-36 0.031
bar-1 Protein BAR-1 0.027
pmk-3 Protein PMK-3 0.026
ocrl-1 Protein OCRL-1 0.022
C13F10.4 Protein C13F10.4 0.021
uaf-1 Protein UAF-1 0.021
zyg-9 Protein ZYG-9 0.020
C15C7.5 Protein C15C7.5 0.019
par-5 Protein PAR-5 0.019
itr-1 Protein ITR-1 0.019
K10D6.4 Protein K10D6.4 0.019
daf-12 Protein DAF-12 0.019
rskn-1 Protein RSKN-1 0.018
nhr-34 Protein NHR-34 0.018
cct-2 Protein CCT-2 0.018
lit-1 Protein LIT-1 0.017
K03H4.2 Protein K03H4.2 0.017
daf-2 Protein DAF-2 0.017
CELE_C08H9.2 Protein C08H9.2 0.017
mac-1 Protein MAC-1 0.017
daf-7 Protein DAF-7 0.016
glp-1 Protein GLP-1 0.016
Y25C1A.5 Protein Y25C1A.5 0.015
CELE_ZK1025.3 Protein ZK1025.3 0.015
unc-43 Protein UNC-43 0.015
lin-25 Protein LIN-25 0.015
daf-14 Protein DAF-14 0.014
lin-45 Protein LIN-45 0.014
K02A6.2 Protein K02A6.2 0.013
sel-8 Protein SEL-8 0.013
prp-8 Protein PRP-8 0.013
mbk-2 Protein MBK-2 0.013
tomm-7 Protein TOMM-7 0.013
csnk-1 Protein CSNK-1 0.013
ncs-2 Protein NCS-2 0.012
T12E12.1 Protein T12E12.1 0.012
chc-1 Protein CHC-1 0.012
zyg-11 Protein ZYG-11 0.012
col-173 Protein COL-173 0.012
csn-5 Protein CSN-5 0.012
Y32F6B.1 Protein Y32F6B.1 0.012
ifa-1 Protein IFA-1 0.012
hat-1 Protein HAT-1 0.012
mel-26 Protein MEL-26 0.011
CELE_Y57G11C.22 Protein Y57G11C.22 0.011
imb-2 Protein IMB-2 0.011
axl-1 Protein AXL-1 0.011
dsh-1 Protein DSH-1 0.011
daf-3 Protein DAF-3 0.011
enu-3 Protein ENU-3 0.011
cki-1 Protein CKI-1 0.011
R10E4.1 Protein R10E4.1 0.011
T22C1.1 Protein T22C1.1 0.010
pme-2 Protein PME-2 0.010
ajm-1 Protein AJM-1 0.010
gpb-1 Protein GPB-1 0.010
cdc-48.1 Protein CDC-48.1 0.010
dsh-2 Protein DSH-2 0.010
CELE_C18C4.5 Protein C18C4.5 0.010
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
dag1 dystroglycan 1 0.676
cdh1 cadherin 1, epithelial 0.662
pitx3 paired-like homeodomain transcription factor 3 0.651
fgf10a fibroblast growth factor 10a 0.649
ef1a elongation factor 1-alpha 0.626
tp53 tumor protein p53 0.623
ptch2 patched 2 0.572
cd63 Cd63 antigen 0.553
mapk3 mitogen-activated protein kinase 3 0.532
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.494
nf1a neurofibromin 1a 0.481
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.446
dlx5a distal-less homeobox gene 5a 0.435
plk1 polo-like kinase 1 (Drosophila) 0.417
fzd7b frizzled homolog 7b 0.405
igf1rb insulin-like growth factor 1b receptor 0.402
pwp2h PWP2 periodic tryptophan protein homolog (yeast) 0.399
rhoab ras homolog gene family, member Ab 0.393
hspa4a heat shock protein 4a 0.385
bmp2b bone morphogenetic protein 2b 0.347
oprm1 opioid receptor, mu 1 0.344
furinb furin (paired basic amino acid cleaving enzyme) b 0.307
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.300
dlat dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) 0.298
cav1 caveolin 1 0.297
chd chordin 0.278
robo3 roundabout homolog 3 0.277
tll1 tolloid-like 1 0.264
bmp4 bone morphogenetic protein 4 0.263
vangl2 vang-like 2 (van gogh, Drosophila) 0.256
vdra vitamin D receptor a 0.249
fbn2b fibrillin 2b 0.247
mapk1 mitogen-activated protein kinase 1 0.244
fgf20a fibroblast growth factor 20a 0.238
wnt11r wingless-type MMTV integration site family, member 11, related 0.235
ctnnb1 catenin (cadherin-associated protein), beta 1 0.234
hif1ab hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b 0.234
ntn2 netrin 2 0.229
notch3 notch homolog 3 0.225
tbx1 T-box 1 0.224
fzd7a frizzled homolog 7a 0.222
tnfrsfa tumor necrosis factor receptor superfamily, member a 0.221
dusp1 dual specificity phosphatase 1 0.221
jun jun proto-oncogene 0.221
smad9 MAD homolog 9 (Drosophila) 0.218
dkk1b dickkopf 1b 0.215
ncoa2 nuclear receptor coactivator 2 0.214
dscam Down syndrome cell adhesion molecule 0.212
ctsl1b cathepsin L, 1 b 0.212
pou1f1 POU domain, class 1, transcription factor 1 0.212
wu:fa27a01 wu:fa27a01 0.211
mapk12 mitogen-activated protein kinase 12 0.210
smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.210
cse1l chromosome segregation 1-like (S. cerevisiae) 0.202
cxcr4a chemokine (C-X-C motif) receptor 4a 0.199
acvr1b activin A receptor, type IB 0.199
lft1 lefty1 0.198
ptenb phosphatase and tensin homolog B (mutated in multiple advanced cancers 1) 0.197
sid4 secreted immunoglobulin domain 4 0.195
aplnra apelin receptor a 0.190
mcl1b myeloid cell leukemia sequence 1b 0.185
axin1 axin 1 0.183
cxcl12a chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1) 0.180
rab11fip4a RAB11 family interacting protein 4 (class II) a 0.180
ppp2r5d protein phosphatase 2, regulatory subunit B', delta 0.176
znf703 zinc finger protein 703 0.174
gdf6a growth differentiation factor 6a 0.170
usp4 ubiquitin specific protease 4 (proto-oncogene) 0.167
ldb1a LIM-domain binding factor 1a 0.167
cdh2 cadherin 2, neuronal 0.166
yes1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 0.166
vgll4l vestigial like 4 like 0.165
LOC100535549 cytoplasmic polyadenylation element-binding protein 4-like 0.164
lmna lamin A 0.162
sulf2l sulfatase 2, like 0.160
twist1a twist1a 0.157
dnaja1l DnaJ (Hsp40) homolog, subfamily A, member 1, like 0.157
mych myelocytomatosis oncogene homolog 0.156
hdac4 histone deacetylase 4 0.156
ndr2 nodal-related 2 0.151
gclc glutamate-cysteine ligase, catalytic subunit 0.150
sox11b SRY-box containing gene 11b 0.148
wnt1 wingless-type MMTV integration site family, member 1 0.147
cdc20 cell division cycle 20 homolog 0.147
flot2a flotillin 2a 0.145
LOC100006361 galanin-like 0.145
plcg1 phospholipase C, gamma 1 0.145
sulf1 sulfatase 1 0.141
nkx2.2a NK2 transcription factor related 2a 0.140
acp5b acid phosphatase 5b, tartrate resistant 0.139
esrra estrogen-related receptor alpha 0.139
gadd45ba growth arrest and DNA-damage-inducible, beta a 0.138
txnrd1 thioredoxin reductase 1 0.137
lef1 lymphocyte enhancer binding factor 1 0.136
ip6k2 inositol hexaphosphate kinase 2 0.135
ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.135
kita kit receptor a 0.135
tlr3 toll-like receptor 3 0.134
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.133
capns1b calpain, small subunit 1 b 0.133
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Akt1 CG4006 gene product from transcript CG4006-RA 0.804
ovo CG6824 gene product from transcript CG6824-RE 0.613
EcR Ecdysone receptor 0.513
Mer Merlin 0.473
RanGap Ran GTPase activating protein 0.424
wg wingless 0.416
Mad Mothers against dpp 0.415
per period 0.378
proPO-A1 prophenol oxidase A1 0.374
pan pangolin 0.344
rhea CG6831 gene product from transcript CG6831-RA 0.337
Dat Dopamine N acetyltransferase 0.332
vg vestigial 0.308
pex10 peroxin 10 0.298
ptc patched 0.294
Stat92E Signal-transducer and activator of transcription protein at 92E 0.284
Tl Toll 0.261
Nup214 Nucleoporin 214 0.238
l(2)gl lethal (2) giant larvae 0.221
Egfr Epidermal growth factor receptor 0.214
Rab11 Rab-protein 11 0.212
sina seven in absentia 0.203
aop anterior open 0.200
dco discs overgrown 0.197
Rel Relish 0.180
E(z) Enhancer of zeste 0.164
14-3-3epsilon CG31196 gene product from transcript CG31196-RA 0.163
smt3 CG4494 gene product from transcript CG4494-RA 0.159
RpII215 RNA polymerase II 215kD subunit 0.159
fz frizzled 0.156
Cul-2 Cullin-2 0.154
Ras85D Ras oncogene at 85D 0.153
Lam Lamin 0.153
Eb1 CG3265 gene product from transcript CG3265-RF 0.152
ben bendless 0.148
eff effete 0.143
Pka-C1 cAMP-dependent protein kinase 1 0.142
RnrL Ribonucleoside diphosphate reductase large subunit 0.142
CG16885 CG16885 gene product from transcript CG16885-RA 0.140
Hcf Host cell factor 0.139
Cul-3 Cullin-3 0.136
tub tube 0.130
tum tumbleweed 0.130
ci cubitus interruptus 0.125
l(1)dd4 lethal (1) discs degenerate 4 0.118
arm armadillo 0.112
CG16884 CG16884 gene product from transcript CG16884-RA 0.107
Myb Myb oncogene-like 0.103
garz gartenzwerg 0.101
CG5931 CG5931 gene product from transcript CG5931-RA 0.098
pex13 peroxin 13 0.097
emb embargoed 0.096
Nup98 Nucleoporin 98 0.095
Nup154 Nucleoporin 154 0.095
wdb widerborst 0.095
nkd naked cuticle 0.093
Ric Ras which interacts with Calmodulin 0.093
pex12 peroxin 12 0.093
Clk Clock 0.092
btl breathless 0.089
Gap1 GTPase-activating protein 1 0.089
Act87E Actin 87E 0.088
mub mushroom-body expressed 0.087
par-6 CG5884 gene product from transcript CG5884-RA 0.086
ttv tout-velu 0.083
smo smoothened 0.082
NFAT NFAT homolog 0.080
BG4 CG12297 gene product from transcript CG12297-RA 0.080
sbb scribbler 0.079
Tip60 CG6121 gene product from transcript CG6121-RA 0.079
Incenp Inner centromere protein 0.078
Kap-alpha3 karyopherin alpha3 0.076
Yp1 Yolk protein 1 0.075
Bre1 CG10542 gene product from transcript CG10542-RA 0.075
Mcr Macroglobulin complement-related 0.075
tai taiman 0.074
shn schnurri 0.073
egh egghead 0.072
dm diminutive 0.072
Abd-B Abdominal B 0.072
Lis-1 Lissencephaly-1 0.070
Obp99b Odorant-binding protein 99b 0.069
EndoGI Endonuclease G inhibitor 0.068
gcm glial cells missing 0.067
CanB Calcineurin B 0.067
betaTub56D beta-Tubulin at 56D 0.067
eve even skipped 0.066
Mtor Megator 0.066
CycB3 Cyclin B3 0.064
eIF-4B Eukaryotic initiation factor 4B 0.063
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.063
Dsor1 Downstream of raf1 0.063
Pp2A-29B Protein phosphatase 2A at 29B 0.062
sktl skittles 0.062
sd scalloped 0.062
pnt pointed 0.061
pont pontin 0.061
en engrailed 0.060
RpI135 RNA polymerase I 135kD subunit 0.060
Spt5 CG7626 gene product from transcript CG7626-RA 0.060
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.990
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.987
ESR1 estrogen receptor 1 0.982
KPNB1 karyopherin (importin) beta 1 0.981
EGFR epidermal growth factor receptor 0.978
PEX19 peroxisomal biogenesis factor 19 0.976
SMAD2 SMAD family member 2 0.971
SMAD7 SMAD family member 7 0.967
PEX14 peroxisomal biogenesis factor 14 0.950
BTRC beta-transducin repeat containing 0.944
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.940
GSK3B glycogen synthase kinase 3 beta 0.935
SMAD3 SMAD family member 3 0.935
ARRB1 arrestin, beta 1 0.919
SMAD4 SMAD family member 4 0.904
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.885
CREBBP CREB binding protein 0.869
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.867
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.862
AXIN1 axin 1 0.846
NCF1 neutrophil cytosolic factor 1 0.832
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.813
CHUK conserved helix-loop-helix ubiquitous kinase 0.788
COPS5 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) 0.751
SH2D4A SH2 domain containing 4A 0.749
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.723
MAPK1 mitogen-activated protein kinase 1 0.709
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.708
NCOA1 nuclear receptor coactivator 1 0.706
BBS10 Bardet-Biedl syndrome 10 0.683
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.646
LAT linker for activation of T cells 0.645
APP amyloid beta (A4) precursor protein 0.620
FOS FBJ murine osteosarcoma viral oncogene homolog 0.617
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.586
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.579
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.568
SP1 Sp1 transcription factor 0.559
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.553
SUFU suppressor of fused homolog (Drosophila) 0.538
TNPO1 transportin 1 0.534
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.533
PEX13 peroxisomal biogenesis factor 13 0.519
HSPA1A heat shock 70kDa protein 1A 0.519
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) 0.518
MYH9 myosin, heavy chain 9, non-muscle 0.516
MYD88 myeloid differentiation primary response gene (88) 0.491
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.490
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.483
AKR1C1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) 0.483
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.480
CCR5 chemokine (C-C motif) receptor 5 0.468
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.466
PSEN1 presenilin 1 0.462
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) 0.448
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 0.444
FLNB filamin B, beta 0.438
AKR1C2 aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) 0.431
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.431
FLNA filamin A, alpha 0.424
PEX5 peroxisomal biogenesis factor 5 0.421
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.420
KAT2B K(lysine) acetyltransferase 2B 0.418
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.404
SMAD1 SMAD family member 1 0.402
CSNK1E casein kinase 1, epsilon 0.398
PRKCZ protein kinase C, zeta 0.397
CDC37 cell division cycle 37 homolog (S. cerevisiae) 0.393
IQGAP1 IQ motif containing GTPase activating protein 1 0.392
RAN RAN, member RAS oncogene family 0.391
CUL2 cullin 2 0.389
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.381
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.381
SPTAN1 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) 0.378
NUP153 nucleoporin 153kDa 0.378
HDAC6 histone deacetylase 6 0.366
GLI1 GLI family zinc finger 1 0.361
UBC ubiquitin C 0.360
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.357
CUL3 cullin 3 0.352
TTR transthyretin 0.349
HSPA1B heat shock 70kDa protein 1B 0.347
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.343
PARP9 poly (ADP-ribose) polymerase family, member 9 0.342
ROD1 ROD1 regulator of differentiation 1 (S. pombe) 0.337
VIM vimentin 0.327
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.326
CKAP5 cytoskeleton associated protein 5 0.323
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 0.321
FKBP1A FK506 binding protein 1A, 12kDa 0.320
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.320
EP300 E1A binding protein p300 0.309
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.304
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 0.300
RAE1 RAE1 RNA export 1 homolog (S. pombe) 0.297
DTX3L deltex 3-like (Drosophila) 0.291
CAV1 caveolin 1, caveolae protein, 22kDa 0.287
IL1R1 interleukin 1 receptor, type I 0.283
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 0.283
RARA retinoic acid receptor, alpha 0.281
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Stip1 stress-induced phosphoprotein 1 0.508
Hsph1 heat shock 105/110 protein 1 0.485
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.455
Mapk1 mitogen activated protein kinase 1 0.247
Ctdsp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 0.190
Gria2 glutamate receptor, ionotropic, AMPA 2 0.127
Tnks2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.126
Chordc1 cysteine and histidine-rich domain (CHORD)-containing 1 0.122
Pfn1 profilin 1 0.118
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.100
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.089
Rbck1 RanBP-type and C3HC4-type zinc finger containing 1 0.082
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.081
Tgfbr2 transforming growth factor, beta receptor II 0.081
Mapk9 mitogen-activated protein kinase 9 0.081
Psmb7 proteasome (prosome, macropain) subunit, beta type 7 0.075
Supt5h suppressor of Ty 5 homolog (S. cerevisiae) 0.070
Hist1h1a histone cluster 1, H1a 0.070
Dctn1 dynactin 1 0.069
Psmc1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.069
Jak2 Janus kinase 2 0.068
Jtb jumping translocation breakpoint 0.067
Icam1 intercellular adhesion molecule 1 0.067
Ppat phosphoribosyl pyrophosphate amidotransferase 0.065
Hspd1 heat shock protein 1 (chaperonin) 0.065
Dnase1l3 deoxyribonuclease 1-like 3 0.064
Fkbp4 FK506 binding protein 4 0.063
Pdcd4 programmed cell death 4 0.061
Rara retinoic acid receptor, alpha 0.060
Bat3 HLA-B-associated transcript 3 0.059
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.055
Pabpc1 poly(A) binding protein, cytoplasmic 1 0.055
Pdgfb platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.054
Ncl nucleolin 0.054
Fgfr1 Fibroblast growth factor receptor 1 0.052
Map2k1 mitogen activated protein kinase kinase 1 0.052
LOC299282 Serine protease inhibitor 0.051
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.050
Dynll1 dynein light chain LC8-type 1 0.049
Gsr glutathione reductase 0.047
Mapk3 mitogen activated protein kinase 3 0.047
Slc12a4 solute carrier family 12 (potassium/chloride transporters), member 4 0.047
Smad7 SMAD family member 7 0.047
Timm23 translocase of inner mitochondrial membrane 23 homolog (yeast) 0.047
Ppp3cb protein phosphatase 3, catalytic subunit, beta isoform 0.045
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.045
Sult1c2 sulfotransferase family, cytosolic, 1C, member 2 0.045
Ppp2r2a protein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform 0.045
Igfbp5 insulin-like growth factor binding protein 5 0.045
Cp ceruloplasmin 0.044
Mprip myosin phosphatase Rho interacting protein 0.043
Ehmt2 euchromatic histone lysine N-methyltransferase 2 0.042
Hspb1 heat shock protein 1 0.041
Hspa8 heat shock protein 8 0.041
Homer1 homer homolog 1 (Drosophila) 0.040
Dnaja1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.040
Gria1 glutamate receptor, ionotropic, AMPA 1 0.040
Nckap1 NCK-associated protein 1 0.040
Clcn7 chloride channel 7 0.039
Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.038
LOC100362155 cysteine and histidine rich 1 0.038
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.037
Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 0.037
Eef2 eukaryotic translation elongation factor 2 0.037
Fkbp1a FK506 binding protein 1a 0.036
Ptgs2 prostaglandin-endoperoxide synthase 2 0.035
St13 suppression of tumorigenicity 13 0.035
Ppp2ca protein phosphatase 2, catalytic subunit, alpha isoform 0.034
Ccnd3 cyclin D3 0.034
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 0.033
Adrb2 adrenergic, beta-2-, receptor, surface 0.033
Gria3 glutamate receptor, ionotrophic, AMPA 3 0.032
Psmb3 proteasome (prosome, macropain) subunit, beta type 3 0.032
LOC100364212 heterogeneous nuclear ribonucleoprotein K-like 0.032
Irs1 insulin receptor substrate 1 0.031
Sf1 splicing factor 1 0.031
Slit3 slit homolog 3 (Drosophila) 0.031
Nfia nuclear factor I/A 0.031
Ubqln1 ubiquilin 1 0.030
Slc15a1 solute carrier family 15 (oligopeptide transporter), member 1 0.030
Stat6 signal transducer and activator of transcription 6 0.030
Pip4k2b phosphatidylinositol-5-phosphate 4-kinase, type II, beta 0.029
Sbk1 SH3-binding domain kinase 1 0.029
Tuba1c tubulin, alpha 1C 0.028
Mapk6 mitogen-activated protein kinase 6 0.027
Tle4 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) 0.027
RGD1559588 similar to cell surface receptor FDFACT 0.026
Ubb ubiquitin B 0.026
Myo1c myosin IC 0.026
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.026
Pard3 par-3 (partitioning defective 3) homolog (C. elegans) 0.025
Cyfip2 cytoplasmic FMR1 interacting protein 2 0.025
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.025
Tcf3 transcription factor 3 0.025
Ptprk protein tyrosine phosphatase, receptor type, K, extracellular region 0.025
Mrpl17 mitochondrial ribosomal protein L17 0.025
Casp2 caspase 2 0.024
Dchs1 dachsous 1 (Drosophila) 0.024
Kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.024
Myd88 myeloid differentiation primary response gene 88 0.024
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
TIM23 Tim23p 1.000
TOM22 Tom22p 1.000
TOM40 Tom40p 1.000
KAP95 Kap95p 0.999
PEX14 Pex14p 0.999
MIA40 Mia40p 0.998
TIM44 Tim44p 0.998
PEX10 Pex10p 0.998
TIM17 Tim17p 0.997
TOM70 Tom70p 0.997
NSP1 Nsp1p 0.994
NUP49 Nup49p 0.994
TIM10 Tim10p 0.994
PEX13 Pex13p 0.993
TOM20 Tom20p 0.992
PEX5 Pex5p 0.991
SSC1 Ssc1p 0.990
PEX19 Pex19p 0.989
NUP145 Nup145p 0.988
NUP2 Nup2p 0.984
SAM35 Sam35p 0.982
NUP170 Nup170p 0.979
TOM5 Tom5p 0.979
TIM50 Tim50p 0.978
PEX15 Pex15p 0.972
PEX17 Pex17p 0.963
TIM18 Tim18p 0.962
PEX11 Pex11p 0.962
KAP123 Kap123p 0.961
PSE1 Pse1p 0.960
TIM13 Tim13p 0.958
TIM9 Tim9p 0.954
CRM1 Crm1p 0.942
NIC96 Nic96p 0.924
PEX8 Pex8p 0.923
NDC1 Ndc1p 0.915
PEX6 Pex6p 0.906
PAM18 Pam18p 0.905
PEX12 Pex12p 0.899
MEX67 Mex67p 0.898
HSP60 Hsp60p 0.898
TIM54 Tim54p 0.880
NUP1 Nup1p 0.861
SAM50 Sam50p 0.840
SLT2 Slt2p 0.836
TIM22 Tim22p 0.832
NUP116 Nup116p 0.830
SRP1 Srp1p 0.822
GLE1 Gle1p 0.820
TIM12 Tim12p 0.797
NUP100 Nup100p 0.789
PEX7 Pex7p 0.769
PEX2 Pex2p 0.766
NUP159 Nup159p 0.763
KAP104 Kap104p 0.750
NUP85 Nup85p 0.731
SSA1 Ssa1p 0.728
YRB1 Yrb1p 0.722
GSP1 Gsp1p 0.718
PEX1 Pex1p 0.693
ERV1 Erv1p 0.677
TOM7 Tom7p 0.675
MGR2 Mgr2p 0.667
KAP114 Kap114p 0.659
PBS2 Pbs2p 0.651
SSA2 Ssa2p 0.647
NUP57 Nup57p 0.621
PAM16 Pam16p 0.583
TIM8 Tim8p 0.566
NUP192 Nup192p 0.564
POT1 Pot1p 0.557
ASM4 Asm4p 0.556
PAM17 Pam17p 0.534
CSE1 Cse1p 0.531
GLE2 Gle2p 0.523
NUP120 Nup120p 0.522
SSE1 Sse1p 0.506
LOS1 Los1p 0.501
SAM37 Sam37p 0.483
MTR10 Mtr10p 0.463
MDM10 Mdm10p 0.463
SIS1 Sis1p 0.424
TIM21 Tim21p 0.418
PEX4 Pex4p 0.417
NUP60 Nup60p 0.397
POM34 Pom34p 0.396
STE11 Ste11p 0.375
SRM1 Srm1p 0.374
PEX3 Pex3p 0.346
NUP157 Nup157p 0.302
MLP2 Mlp2p 0.297
YJR012C hypothetical protein 0.287
RNA1 Rna1p 0.283
ARX1 Arx1p 0.281
TPM1 Tpm1p 0.275
MLP1 Mlp1p 0.273
FCJ1 Fcj1p 0.263
NUP82 Nup82p 0.254
MGR3 Mgr3p 0.253
CTK1 Ctk1p 0.245