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Process View

Drosophila melanogaster

22 genes annotated in fly

dna endoreduplication

GO:0042023

Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "dna endoreduplication"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "dna endoreduplication" (in gray)

Name	Description	Probability	Func Analog Organism
slp1	sloppy paired 1	0.776	Fly
Dp	DP transcription factor	0.727
Mcm10	Sensitized chromosome inheritance modifier 19	0.680
Mcm2	Minichromosome maintenance 2	0.639
Orc2	Origin recognition complex subunit 2	0.626
jumu	jumeau	0.507
dup	double parked	0.485
CG9772	CG9772 gene product from transcript CG9772-RB	0.346
hd	humpty dumpty	0.333
Mcm5	Minichromosome maintenance 5	0.279
Slbp	Stem-loop binding protein	0.269
gsb	gooseberry	0.251
CDC45L	CG3658 gene product from transcript CG3658-RA	0.249
dnt	doughnut on 2	0.212
CycE	Cyclin E	0.192	Worm
pic	piccolo	0.187
nej	nejire	0.173
tos	tosca	0.173
twi	twist	0.172
tll	tailless	0.169
Hmr	Hybrid male rescue	0.167
CG13350	CG13350 gene product from transcript CG13350-RA	0.165
Ndc80	CG9938 gene product from transcript CG9938-RA	0.156
rod	rough deal	0.154
tin	tinman	0.153
nkd	naked cuticle	0.152
cdc16	CG6759 gene product from transcript CG6759-RA	0.151
slp2	sloppy paired 2	0.145	Fly
pds5	CG17509 gene product from transcript CG17509-RA	0.141
E(bx)	Enhancer of bithorax	0.139
byn	brachyenteron	0.137
Top2	Topoisomerase 2	0.136
dpa	disc proliferation abnormal	0.130
kni	knirps	0.128
Orc5	Origin recognition complex subunit 5	0.127
CG14869	CG14869 gene product from transcript CG14869-RB	0.125
Rca1	Regulator of cyclin A1	0.120
btl	breathless	0.104
RnrL	Ribonucleoside diphosphate reductase large subunit	0.102
Notum	CG13076 gene product from transcript CG13076-RB	0.102
hkb	huckebein	0.101
Klp61F	Kinesin-like protein at 61F	0.096
Traf4	TNF-receptor-associated factor 4	0.092
tld	tolloid	0.091
Yeti	CG40218 gene product from transcript CG40218-RA	0.086
ph-d	polyhomeotic distal	0.085
odd	odd skipped	0.082
lat	latheo	0.081
chico	CG5686 gene product from transcript CG5686-RB	0.078
asf1	anti-silencing factor 1	0.069
mip120	Myb-interacting protein 120	0.067
Nuf2	CG8902 gene product from transcript CG8902-RA	0.060
CG9316	CG9316 gene product from transcript CG9316-RA	0.060
Btk29A	Btk family kinase at 29A	0.059
mus209	mutagen-sensitive 209	0.059
Caf1-105	CG12892 gene product from transcript CG12892-RA	0.058
gt	giant	0.057
CG3407	CG3407 gene product from transcript CG3407-RA	0.056
mus101	mutagen-sensitive 101	0.056
skpA	CG16983 gene product from transcript CG16983-RD	0.056
fne	found in neurons	0.055
l(2)05714	lethal (2) 05714	0.054
Mcm6	Minichromosome maintenance 6	0.053
DNApol-alpha60	DNA polymerase alpha 60kD	0.051
BCL7-like	CG17252 gene product from transcript CG17252-RA	0.047
DNApol-alpha73	DNA polymerase alpha 73kD	0.047
cta	concertina	0.046
CG3430	CG3430 gene product from transcript CG3430-RA	0.046
plu	plutonium	0.046
en	engrailed	0.045
rib	ribbon	0.044
path	pathetic	0.044
Ets97D	Ets at 97D	0.043
CG3508	CG3508 gene product from transcript CG3508-RB	0.042
Orc6	Origin recognition complex subunit 6	0.041
luna	CG33473 gene product from transcript CG33473-RB	0.037
Cks30A	Cyclin-dependent kinase subunit 30A	0.037
HLH54F	CG5005 gene product from transcript CG5005-RA	0.037
piwi	CG6122 gene product from transcript CG6122-RA	0.036
chm	chameau	0.036
rad50	CG6339 gene product from transcript CG6339-RD	0.036
jeb	jelly belly	0.036
CG14937	CG14937 gene product from transcript CG14937-RA	0.034
eg	eagle	0.034
Mcm3	Minichromosome maintenance 3	0.033
hep	hemipterous	0.033
Kmn1	kinetochore Mis12-Ndc80 network component 1	0.032
ex	expanded	0.032
Top1	Topoisomerase 1	0.032
neb	nebbish	0.031
toc	toucan	0.031
cmet	CENP-meta	0.031
run	runt	0.029
Cdk4	Cyclin-dependent kinase 4	0.029
Rab23	CG2108 gene product from transcript CG2108-RA	0.028
CycA	Cyclin A	0.028
kek5	kekkon5	0.028
Trf2	TATA box binding protein-related factor 2	0.028
CG5792	CG5792 gene product from transcript CG5792-RA	0.027
CG5694	CG5694 gene product from transcript CG5694-RA	0.027
gcm	glial cells missing	0.027
wda	will decrease acetylation	0.027
sr	stripe	0.026
bin	biniou	0.026	Fly
DNApol-alpha50	DNA polymerase alpha 50kD	0.026
CycD	Cyclin D	0.026
CG10984	CG10984 gene product from transcript CG10984-RC	0.025
Spc105R	Spc105-related	0.024
pdm2	POU domain protein 2	0.024
B52	CG10851 gene product from transcript CG10851-RB	0.024
mars	CG17064 gene product from transcript CG17064-RB	0.024
Cdc6	CG5971 gene product from transcript CG5971-RA	0.024
btsz	bitesize	0.024
lmd	lame duck	0.023
bnl	branchless	0.023
mid	midline	0.023
png	pan gu	0.022
cdc2c	CG10498 gene product from transcript CG10498-RC	0.022
Pten	CG5671 gene product from transcript CG5671-RB	0.021
Gprk2	G protein-coupled receptor kinase 2	0.021
nxf2	nuclear RNA export factor 2	0.021
Ptp69D	Protein tyrosine phosphatase 69D	0.021
qua	quail	0.021
stg	string	0.020
tefu	telomere fusion	0.020
sub	subito	0.019
dgt6	dim gamma-tubulin 6	0.019
opa	odd paired	0.019
Vps16A	Vacuolar protein sorting 16A	0.019
wor	worniu	0.019
mip130	Myb-interacting protein 130	0.018
vtd	verthandi	0.018
Orc1	Origin recognition complex subunit 1	0.017
dib	disembodied	0.017
pxb	CG33207 gene product from transcript CG33207-RB	0.017
DNApol-epsilon	DNA polymerase epsilon	0.017
poly	CG9829 gene product from transcript CG9829-RB	0.017
Cpsf160	Cleavage and polyadenylation specificity factor 160	0.017
CG14005	CG14005 gene product from transcript CG14005-RA	0.017
Wnt4	Wnt oncogene analog 4	0.017	Fly
obst-A	obstructor-A	0.017
dy	dusky	0.017
Rbf	Retinoblastoma-family protein	0.017
WRNexo	WRN exonuclease	0.016
Taf7	TBP-associated factor 7	0.016
Dlic	Dynein light intermediate chain	0.016
CG5794	CG5794 gene product from transcript CG5794-RB	0.016
mms4	CG12936 gene product from transcript CG12936-RA	0.016
Sulf1	Sulfated	0.016
CBP	sarcoplasmic calcium-binding protein	0.016
Fas3	Fasciclin 3	0.016
gnu	giant nuclei	0.015
RpLP1	Ribosomal protein LP1	0.015
nimC3	nimrod C3	0.015
hbs	hibris	0.015
eco	CG8598 gene product from transcript CG8598-RA	0.015
Cdk8	Cyclin-dependent kinase 8	0.015
CAP-D2	CAP-D2 condensin subunit	0.015
pyr	pyramus	0.015
Hcf	Host cell factor	0.015
spo	spook	0.015
CG4771	CG4771 gene product from transcript CG4771-RA	0.015
tlk	Tousled-like kinase	0.015
Acf1	ATP-dependent chromatin assembly factor large subunit	0.015
BubR1	Bub1-related kinase	0.014
CG3563	CG3563 gene product from transcript CG3563-RA	0.014
Myb	Myb oncogene-like	0.014
jub	Ajuba LIM protein	0.014
plx	pollux	0.014
kel	kelch	0.014
CTCF	CG8591 gene product from transcript CG8591-RA	0.014
sd	scalloped	0.014
btn	buttonless	0.014
CG4221	CG4221 gene product from transcript CG4221-RA	0.014
l(2)dtl	lethal-(2)-denticleless	0.014
sec15	CG7034 gene product from transcript CG7034-RA	0.014
CG5815	CG5815 gene product from transcript CG5815-RB	0.014
wntD	wnt inhibitor of Dorsal	0.013	Fly
fs(1)Yb	female sterile (1) Yb	0.013
bcd	bicoid	0.013
CG14317	CG14317 gene product from transcript CG14317-RA	0.013
mei-P26	CG12218 gene product from transcript CG12218-RA	0.013
uif	uninflatable	0.013
Ars2	CG7843 gene product from transcript CG7843-RA	0.013
fkh	fork head	0.013
Ripalpha	RPA-interacting protein alpha	0.013
CG9821	CG9821 gene product from transcript CG9821-RB	0.013
CG2990	CG2990 gene product from transcript CG2990-RB	0.013
CG8247	CG8247 gene product from transcript CG8247-RB	0.013
slou	slouch	0.013
CG7145	CG7145 gene product from transcript CG7145-RD	0.013
CG14814	CG14814 gene product from transcript CG14814-RA	0.013
ik2	IkappaB kinase-like 2	0.013
raw	CG12437 gene product from transcript CG12437-RB	0.013
zwilch	CG18729 gene product from transcript CG18729-RA	0.012
Gen	XPG-like endonuclease	0.012
pip	pipe	0.012
grh	grainy head	0.012
CG14204	CG14204 gene product from transcript CG14204-RA	0.012
Sas-4	CG10061 gene product from transcript CG10061-RA	0.012
rempA	reduced mechanoreceptor potential A	0.012
CG11248	CG11248 gene product from transcript CG11248-RB	0.012
CG10880	CG10880 gene product from transcript CG10880-RA	0.012
Gsc	Goosecoid	0.012
CG7156	CG7156 gene product from transcript CG7156-RA	0.012
BthD	BthD selenoprotein	0.012
Kr	Kruppel	0.012
CG14614	CG14614 gene product from transcript CG14614-RA	0.011
cutlet	CG33122 gene product from transcript CG33122-RA	0.011
pr-set7	CG3307 gene product from transcript CG3307-RC	0.011
hh	hedgehog	0.011
CG9413	CG9413 gene product from transcript CG9413-RA	0.011
swa	swallow	0.011
croc	crocodile	0.011
pzg	putzig	0.011
ase	asense	0.011
H2.0	Homeodomain protein 2.0	0.011
ec	echinus	0.011
rux	roughex	0.011
Dref	DNA replication-related element factor	0.011
SuUR	Suppressor of Under-Replication	0.011
CG4449	CG4449 gene product from transcript CG4449-RB	0.011
CG8079	CG8079 gene product from transcript CG8079-RA	0.011
Wnt6	CG4969 gene product from transcript CG4969-RB	0.011
Gap1	GTPase-activating protein 1	0.011
defl	deflated	0.011
inx2	innexin 2	0.011
CG9541	CG9541 gene product from transcript CG9541-RA	0.011
inv	invected	0.011
otk	off-track	0.011
CG13983	CG13983 gene product from transcript CG13983-RA	0.011
brk	brinker	0.011
Blimp-1	CG5249 gene product from transcript CG5249-RA	0.011
CG1104	CG1104 gene product from transcript CG1104-RB	0.010
disco	disconnected	0.010
CG13928	CG13928 gene product from transcript CG13928-RA	0.010
CG3081	CG3081 gene product from transcript CG3081-RA	0.010
Pnn	Pinin	0.010
CG9576	CG9576 gene product from transcript CG9576-RA	0.010
nod	no distributive disjunction	0.010
Nup160	Nucleoporin 160	0.010
rho-5	rhomboid-5	0.010
fs(1)M3	female sterile (1) M3	0.010
alpha-Cat	alpha Catenin	0.010
CG8924	CG8924 gene product from transcript CG8924-RB	0.010
hpo	hippo	0.010
klg	klingon	0.010
pnr	pannier	0.010
nrv2	nervana 2	0.010
Sse	Separase	0.010
CG6254	CG6254 gene product from transcript CG6254-RA	0.010
Msi	Male-specific insect derived growth factor	0.010
CG32486	CG32486 gene product from transcript CG32486-RD	0.010