IMP

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Mus musculus

1 genes annotated in mouse

Multi-species View

negative regulation of chromatin silencing

GO:0031936

Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of chromatin silencing"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of chromatin silencing" (in gray)

Name	Description	Probability	Func Analog Organism
Arid1a	AT rich interactive domain 1A (SWI-like)	0.996
Hdac1	histone deacetylase 1	0.870
Suds3	suppressor of defective silencing 3 homolog (S. cerevisiae)	0.816
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.798
Ncor1	nuclear receptor co-repressor 1	0.721
Hdac2	histone deacetylase 2	0.550
Mcm2	minichromosome maintenance deficient 2 mitotin (S. cerevisiae)	0.509
Mcm3	minichromosome maintenance deficient 3 (S. cerevisiae)	0.502
Pum2	pumilio 2 (Drosophila)	0.481
Smarcc1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.350
Arid2	AT rich interactive domain 2 (ARID, RFX-like)	0.235	Fly
Ep300	E1A binding protein p300	0.209
Sp1	trans-acting transcription factor 1	0.209
Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)	0.189
Kdm5b	lysine (K)-specific demethylase 5B	0.188
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.170
Hist1h2bc	histone cluster 1, H2bc	0.162
Dnmt1	DNA methyltransferase (cytosine-5) 1	0.160
Mcm6	minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)	0.155
Ctcf	CCCTC-binding factor	0.151
Bod1l	biorientation of chromosomes in cell division 1-like	0.135
Mcm7	minichromosome maintenance deficient 7 (S. cerevisiae)	0.128
Smarca2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.126
Tcf3	transcription factor 3	0.116
Cdt1	chromatin licensing and DNA replication factor 1	0.115
Nipbl	Nipped-B homolog (Drosophila)	0.110
Sap25	sin3 associated polypeptide	0.108
Trp53	transformation related protein 53	0.103
Smad4	MAD homolog 4 (Drosophila)	0.099
Mll5	myeloid/lymphoid or mixed-lineage leukemia 5	0.095
Cdk2	cyclin-dependent kinase 2	0.093
Pold1	polymerase (DNA directed), delta 1, catalytic subunit	0.087
Timeless	timeless homolog (Drosophila)	0.084
Rnf220	ring finger protein 220	0.081
Racgap1	Rac GTPase-activating protein 1	0.080
Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.071
Zfp292	zinc finger protein 292	0.068
Crebbp	CREB binding protein	0.067
Lig1	ligase I, DNA, ATP-dependent	0.066
Yy1	YY1 transcription factor	0.062
Asxl1	additional sex combs like 1 (Drosophila)	0.062
Foxp1	forkhead box P1	0.061
Rrm2	ribonucleotide reductase M2	0.061
Ccna2	cyclin A2	0.061
Pbrm1	polybromo 1	0.058	Fly
Cnot6	CCR4-NOT transcription complex, subunit 6	0.054
Angel2	angel homolog 2 (Drosophila)	0.053
Rfc5	replication factor C (activator 1) 5	0.051
Nono	non-POU-domain-containing, octamer binding protein	0.047
Rnf38	ring finger protein 38	0.047
Ncapg2	non-SMC condensin II complex, subunit G2	0.046
Prkd3	protein kinase D3	0.045
Nanog	Nanog homeobox	0.043
Tk1	thymidine kinase 1	0.043
Rad54l	RAD54 like (S. cerevisiae)	0.042
Mll1	myeloid/lymphoid or mixed-lineage leukemia 1	0.041
Rcor1	REST corepressor 1	0.041
Rrm1	ribonucleotide reductase M1	0.041
Rcc1	regulator of chromosome condensation 1	0.041
8430410K20Rik	RIKEN cDNA 8430410K20 gene	0.038
Tet1	tet oncogene 1	0.038
Jarid2	jumonji, AT rich interactive domain 2	0.038
Zmym5	zinc finger, MYM-type 5	0.038
Pias1	protein inhibitor of activated STAT 1	0.037
Tcfcp2l1	transcription factor CP2-like 1	0.037
Hcfc1	host cell factor C1	0.035
Zmym4	zinc finger, MYM-type 4	0.035
Ncoa6	nuclear receptor coactivator 6	0.034
Rara	retinoic acid receptor, alpha	0.034
Ccne1	cyclin E1	0.034
Pole	polymerase (DNA directed), epsilon	0.034
Pou2f1	POU domain, class 2, transcription factor 1	0.034
Rpa2	replication protein A2	0.033
Fam76b	family with sequence similarity 76, member B	0.032
Pum1	pumilio 1 (Drosophila)	0.032
Pou5f1	POU domain, class 5, transcription factor 1	0.031
Kdm1a	lysine (K)-specific demethylase 1A	0.031
Smad1	MAD homolog 1 (Drosophila)	0.031
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.030
Gtf3c2	general transcription factor IIIC, polypeptide 2, beta	0.030
Atm	ataxia telangiectasia mutated homolog (human)	0.030
Ss18	synovial sarcoma translocation, Chromosome 18	0.030
Nfatc3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	0.029
Sox2	SRY-box containing gene 2	0.029
Rad50	RAD50 homolog (S. cerevisiae)	0.029
Mecp2	methyl CpG binding protein 2	0.029
Chd4	chromodomain helicase DNA binding protein 4	0.028
Pld3	phospholipase D family, member 3	0.028
Msl1	male-specific lethal 1 homolog (Drosophila)	0.028
Fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.027
Numa1	nuclear mitotic apparatus protein 1	0.027
Ylpm1	YLP motif containing 1	0.027
Ncapd3	non-SMC condensin II complex, subunit D3	0.027
Tmem115	transmembrane protein 115	0.027
Arid1b	AT rich interactive domain 1B (SWI-like)	0.026
Tex264	testis expressed gene 264	0.026
Tmem131	transmembrane protein 131	0.026
Etv6	ets variant gene 6 (TEL oncogene)	0.025
Brd4	bromodomain containing 4	0.025
Mta2	metastasis-associated gene family, member 2	0.025
Kdm2b	lysine (K)-specific demethylase 2B	0.025
Huwe1	HECT, UBA and WWE domain containing 1	0.024
Top2b	topoisomerase (DNA) II beta	0.024
Tpr	translocated promoter region	0.024
Cnot6l	CCR4-NOT transcription complex, subunit 6-like	0.024
Kdm3b	KDM3B lysine (K)-specific demethylase 3B	0.024
Zc3h11a	zinc finger CCCH type containing 11A	0.024
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.024
Hp1bp3	heterochromatin protein 1, binding protein 3	0.024
Scaf11	SR-related CTD-associated factor 11	0.023
Igh	immunoglobulin heavy chain complex	0.023
Ube2r2	ubiquitin-conjugating enzyme E2R 2	0.023
Prdm1	PR domain containing 1, with ZNF domain	0.022
Incenp	inner centromere protein	0.022
Rad21	RAD21 homolog (S. pombe)	0.022
Lbr	lamin B receptor	0.022
Cdk6	cyclin-dependent kinase 6	0.021
Bmi1	Bmi1 polycomb ring finger oncogene	0.021
Mnt	max binding protein	0.021
Cdca5	cell division cycle associated 5	0.021
Tm2d2	TM2 domain containing 2	0.021
Cnot2	CCR4-NOT transcription complex, subunit 2	0.021
Hnrnph3	heterogeneous nuclear ribonucleoprotein H3	0.021
Grina	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)	0.021
Qser1	glutamine and serine rich 1	0.021
Gadd45a	growth arrest and DNA-damage-inducible 45 alpha	0.021
Mthfd1l	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like	0.020
Tcf4	transcription factor 4	0.020
Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1	0.020
Flot1	flotillin 1	0.020
Dnajc9	DnaJ (Hsp40) homolog, subfamily C, member 9	0.020
Epc2	enhancer of polycomb homolog 2 (Drosophila)	0.020
Cramp1l	Crm, cramped-like (Drosophila)	0.020
Rdx	radixin	0.020
Ammecr1l	AMME chromosomal region gene 1-like	0.020
Sufu	suppressor of fused homolog (Drosophila)	0.020
Capns1	calpain, small subunit 1	0.020
Tcf12	transcription factor 12	0.020
Tnrc6c	trinucleotide repeat containing 6C	0.020
Pcm1	pericentriolar material 1	0.020
Terf2	telomeric repeat binding factor 2	0.020
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.020
Fam111a	family with sequence similarity 111, member A	0.019
Tubb5	tubulin, beta 5	0.019
Gatad2a	GATA zinc finger domain containing 2A	0.019
Smc6	structural maintenance of chromosomes 6	0.019
Ncapd2	non-SMC condensin I complex, subunit D2	0.019
Orc1	origin recognition complex, subunit 1	0.019
Patz1	POZ (BTB) and AT hook containing zinc finger 1	0.019
Cdca7	cell division cycle associated 7	0.019
Espl1	extra spindle poles-like 1 (S. cerevisiae)	0.019
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.019
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.019
Tia1	cytotoxic granule-associated RNA binding protein 1	0.019
Sfpi1	SFFV proviral integration 1	0.018
Bub1b	budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)	0.018
Clk2	CDC-like kinase 2	0.018
Casp2	caspase 2	0.018
Smarcc2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.018
Ccar1	cell division cycle and apoptosis regulator 1	0.018
Rock1	Rho-associated coiled-coil containing protein kinase 1	0.018
Irf8	interferon regulatory factor 8	0.018
E2f1	E2F transcription factor 1	0.018
Ikzf1	IKAROS family zinc finger 1	0.018
Arhgap21	Rho GTPase activating protein 21	0.017
Mki67	antigen identified by monoclonal antibody Ki 67	0.017
Hmgb1	high mobility group box 1	0.017
Zcchc8	zinc finger, CCHC domain containing 8	0.017
Mcl1	myeloid cell leukemia sequence 1	0.017
Tmem173	transmembrane protein 173	0.017
Zfp161	zinc finger protein 161	0.017
Dennd4c	DENN/MADD domain containing 4C	0.017
Tmpo	thymopoietin	0.017
Rfc1	replication factor C (activator 1) 1	0.017
G2e3	G2/M-phase specific E3 ubiquitin ligase	0.017
Rhog	ras homolog gene family, member G	0.017
Kdm3a	lysine (K)-specific demethylase 3A	0.017
Hnrnpul2	heterogeneous nuclear ribonucleoprotein U-like 2	0.016
Tuba1b	tubulin, alpha 1B	0.016
Cdc25a	cell division cycle 25 homolog A (S. pombe)	0.016
Ctbp2	C-terminal binding protein 2	0.016
Rest	RE1-silencing transcription factor	0.016
Gltp	glycolipid transfer protein	0.016
Baz2a	bromodomain adjacent to zinc finger domain, 2A	0.016
2210018M11Rik	RIKEN cDNA 2210018M11 gene	0.016
Smc4	structural maintenance of chromosomes 4	0.016
Cdca4	cell division cycle associated 4	0.016
Rabac1	Rab acceptor 1 (prenylated)	0.016
Tnrc6a	trinucleotide repeat containing 6a	0.016
Maml1	mastermind like 1 (Drosophila)	0.016
Sap30	sin3 associated polypeptide	0.016
Baz1b	bromodomain adjacent to zinc finger domain, 1B	0.016
Gabarap	gamma-aminobutyric acid receptor associated protein	0.015
Lgals3	lectin, galactose binding, soluble 3	0.015
Brd1	bromodomain containing 1	0.015
Stag2	stromal antigen 2	0.015
Srsf4	serine/arginine-rich splicing factor 4	0.015
Rcc2	regulator of chromosome condensation 2	0.015
Anp32a	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	0.015
Smarce1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	0.015
Ncaph	non-SMC condensin I complex, subunit H	0.015
Pml	promyelocytic leukemia	0.015
Dek	DEK oncogene (DNA binding)	0.014
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.014
Hist2h4	histone cluster 2, H4	0.014
Grsf1	G-rich RNA sequence binding factor 1	0.014
Phf12	PHD finger protein 12	0.014
Zfp422	zinc finger protein 422	0.014
Tom1	target of myb1 homolog (chicken)	0.014
Suv39h1	suppressor of variegation 3-9 homolog 1 (Drosophila)	0.014
Msl2	male-specific lethal 2 homolog (Drosophila)	0.014
Mbtd1	mbt domain containing 1	0.014
Msr1	macrophage scavenger receptor 1	0.014
Polr2a	polymerase (RNA) II (DNA directed) polypeptide A	0.014
Cstf2t	cleavage stimulation factor, 3' pre-RNA subunit 2, tau	0.014
Cdk4	cyclin-dependent kinase 4	0.014
Pcbp2	poly(rC) binding protein 2	0.014
Rpa1	replication protein A1	0.014
Tnrc6b	trinucleotide repeat containing 6b	0.014
Zmynd11	zinc finger, MYND domain containing 11	0.014
Sp3	trans-acting transcription factor 3	0.014
E2f4	E2F transcription factor 4	0.014
Bptf	bromodomain PHD finger transcription factor	0.014
Daxx	Fas death domain-associated protein	0.014
Cdc7	cell division cycle 7 (S. cerevisiae)	0.014
Mms22l	MMS22-like, DNA repair protein	0.014
Mier3	mesoderm induction early response 1, family member 3	0.014
Zfp148	zinc finger protein 148	0.013
Rnf145	ring finger protein 145	0.013
Styx	serine/threonine/tyrosine interaction protein	0.013
Txnip	thioredoxin interacting protein	0.013
Gins3	GINS complex subunit 3 (Psf3 homolog)	0.013
Syf2	SYF2 homolog, RNA splicing factor (S. cerevisiae)	0.013
Med23	mediator complex subunit 23	0.013
Atad2b	ATPase family, AAA domain containing 2B	0.013
Pabpn1	poly(A) binding protein, nuclear 1	0.013
Actn4	actinin alpha 4	0.013
Tesk1	testis specific protein kinase 1	0.013
Hist2h3c2-ps	histone cluster 2, H3c2, pseudogene	0.013
Wnk1	WNK lysine deficient protein kinase 1	0.013
Brd8	bromodomain containing 8	0.013
Atf7ip	activating transcription factor 7 interacting protein	0.013
Lsm14b	LSM14 homolog B (SCD6, S. cerevisiae)	0.013
Taf4a	TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.013
Rfc3	replication factor C (activator 1) 3	0.013
Dnajc4	DnaJ (Hsp40) homolog, subfamily C, member 4	0.013
Vasp	vasodilator-stimulated phosphoprotein	0.013
Hmmr	hyaluronan mediated motility receptor (RHAMM)	0.013
Tlr1	toll-like receptor 1	0.013
Ldb1	LIM domain binding 1	0.013
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.013
Pold3	polymerase (DNA-directed), delta 3, accessory subunit	0.013
Brd3	bromodomain containing 3	0.013
Hck	hemopoietic cell kinase	0.013
Map3k1	mitogen-activated protein kinase kinase kinase 1	0.013
Mll3	myeloid/lymphoid or mixed-lineage leukemia 3	0.013
Chd7	chromodomain helicase DNA binding protein 7	0.013
Arrdc3	arrestin domain containing 3	0.012
Hnrnpr	heterogeneous nuclear ribonucleoprotein R	0.012
H2afy	H2A histone family, member Y	0.012
Ccnd1	cyclin D1	0.012
Lmnb1	lamin B1	0.012
Bscl2	Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)	0.012
S100pbp	S100P binding protein	0.012
Setx	senataxin	0.012
Hrc	histidine rich calcium binding protein	0.012
Mylpf	myosin light chain, phosphorylatable, fast skeletal muscle	0.012
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.012
Pola2	polymerase (DNA directed), alpha 2	0.012
Ripk3	receptor-interacting serine-threonine kinase 3	0.012
Tshz1	teashirt zinc finger family member 1	0.012
Myo1c	myosin IC	0.012
Tor3a	torsin family 3, member A	0.012
Rab4b	RAB4B, member RAS oncogene family	0.012
Haus8	4HAUS augmin-like complex, subunit 8	0.012
Tnni2	troponin I, skeletal, fast 2	0.012
Dido1	death inducer-obliterator 1	0.012
Epc1	enhancer of polycomb homolog 1 (Drosophila)	0.012
Cdc6	cell division cycle 6 homolog (S. cerevisiae)	0.012
Ccnd2	cyclin D2	0.012
Foxk1	forkhead box K1	0.012
Ifi203	interferon activated gene 203	0.012
Tnnt3	troponin T3, skeletal, fast	0.012
Exoc7	exocyst complex component 7	0.012
Tprgl	transformation related protein 63 regulated like	0.012
Abhd4	abhydrolase domain containing 4	0.012
Napa	N-ethylmaleimide sensitive fusion protein attachment protein alpha	0.012
Mfap1a	microfibrillar-associated protein 1A	0.012
Phc1	polyhomeotic-like 1 (Drosophila)	0.012
Irf9	interferon regulatory factor 9	0.011
Cbfb	core binding factor beta	0.011
Phkb	phosphorylase kinase beta	0.011
Ckap2	cytoskeleton associated protein 2	0.011
Ep400	E1A binding protein p400	0.011
Zfp871	zinc finger protein 871	0.011
Myst3	MYST histone acetyltransferase (monocytic leukemia) 3	0.011
Cdc42ep3	CDC42 effector protein (Rho GTPase binding) 3	0.011
Pgam2	phosphoglycerate mutase 2	0.011
Pura	purine rich element binding protein A	0.011
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.011
Tbl1x	transducin (beta)-like 1 X-linked	0.011
H2afx	H2A histone family, member X	0.011
Smarcb1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.011
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.011
Kdm4c	lysine (K)-specific demethylase 4C	0.011
Sh3gl1	SH3-domain GRB2-like 1	0.011
Tcta	T-cell leukemia translocation altered gene	0.011
Tmem106a	transmembrane protein 106A	0.011
Hist1h2bp	histone cluster 1, H2bp	0.011
Gpr65	G-protein coupled receptor 65	0.011
Actn2	actinin alpha 2	0.011
Gpsm2	G-protein signalling modulator 2 (AGS3-like, C. elegans)	0.011
Tmem188	transmembrane protein 188	0.011
Vezf1	vascular endothelial zinc finger 1	0.011
Ssbp2	single-stranded DNA binding protein 2	0.011
Cdca8	cell division cycle associated 8	0.011
Topbp1	topoisomerase (DNA) II binding protein 1	0.011
Casp1	caspase 1	0.011
Gdi2	guanosine diphosphate (GDP) dissociation inhibitor 2	0.011
Lgals3bp	lectin, galactoside-binding, soluble, 3 binding protein	0.011
Sin3a	transcriptional regulator, SIN3A (yeast)	0.011	Yeast
R3hdm1	R3H domain 1 (binds single-stranded nucleic acids)	0.011
Trim21	tripartite motif-containing 21	0.011
Bcl3	B-cell leukemia/lymphoma 3	0.011
Macf1	microtubule-actin crosslinking factor 1	0.011
Gpatch8	G patch domain containing 8	0.011
Mbnl1	muscleblind-like 1 (Drosophila)	0.011
Atad5	ATPase family, AAA domain containing 5	0.011
Zfp740	zinc finger protein 740	0.011
Rbbp7	retinoblastoma binding protein 7	0.011
Adipor1	adiponectin receptor 1	0.010
Ctsd	cathepsin D	0.010
Cd27	CD27 antigen	0.010
Tmod4	tropomodulin 4	0.010
Dcaf15	DDB1 and CUL4 associated factor 15	0.010
Usp18	ubiquitin specific peptidase 18	0.010
Apitd1	apoptosis-inducing, TAF9-like domain 1	0.010
Pts	6-pyruvoyl-tetrahydropterin synthase	0.010
Dazap1	DAZ associated protein 1	0.010
Casq1	calsequestrin 1	0.010
Cdk1	cyclin-dependent kinase 1	0.010
Kdm1b	lysine (K)-specific demethylase 1B	0.010
Tcof1	Treacher Collins Franceschetti syndrome 1, homolog	0.010
Ncoa1	nuclear receptor coactivator 1	0.010
Sfpq	splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)	0.010
Hist1h2ao	histone cluster 1, H2ao	0.010
Sall4	sal-like 4 (Drosophila)	0.010
Ehmt1	euchromatic histone methyltransferase 1	0.010
Senp1	SUMO1/sentrin specific peptidase 1	0.010
Eif4g3	eukaryotic translation initiation factor 4 gamma, 3	0.010
Atg13	ATG13 autophagy related 13 homolog (S. cerevisiae)	0.010
Tab3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	0.010
Dock7	dedicator of cytokinesis 7	0.010
Rbm14	RNA binding motif protein 14	0.010
Sap130	Sin3A associated protein	0.010
Ifi44	interferon-induced protein 44	0.010
Ubn1	ubinuclein 1	0.010
Tdrd3	tudor domain containing 3	0.010
Ubtf	upstream binding transcription factor, RNA polymerase I	0.010