The network for 'positive regulation of map kinase activity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of map kinase activity

Any process that activates or increases the frequency, rate or extent of MAP kinase activity.

Mus musculus
Name Description Probability Func Analog Organism
Efnb2 ephrin B2 0.995
Grb2 growth factor receptor bound protein 2 0.995
Ctnnb1 catenin (cadherin associated protein), beta 1 0.995
Psen1 presenilin 1 0.994
Tnf tumor necrosis factor 0.993
Lepr leptin receptor 0.993
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.993
Tgfb2 transforming growth factor, beta 2 0.992
Inpp5d inositol polyphosphate-5-phosphatase D 0.989
Traf6 TNF receptor-associated factor 6 0.986
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.984
Pten phosphatase and tensin homolog 0.983
Csf1 colony stimulating factor 1 (macrophage) 0.981
Src Rous sarcoma oncogene 0.978
Lyz2 lysozyme 2 0.977
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.970
Egfr epidermal growth factor receptor 0.965
Notch2 Notch gene homolog 2 (Drosophila) 0.957
Axl AXL receptor tyrosine kinase 0.943
Cd44 CD44 antigen 0.934
Cbl Casitas B-lineage lymphoma 0.931
Nos1 nitric oxide synthase 1, neuronal 0.924
Dvl2 dishevelled 2, dsh homolog (Drosophila) 0.924
Jag1 jagged 1 0.916
Fyn Fyn proto-oncogene 0.904
Ephb2 Eph receptor B2 0.904
Ret ret proto-oncogene 0.898
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.853
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.846
Vangl2 vang-like 2 (van gogh, Drosophila) 0.844
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.839
Btk Bruton agammaglobulinemia tyrosine kinase 0.839
Plcg1 phospholipase C, gamma 1 0.830
Cd40 CD40 antigen 0.816
Ccr1 chemokine (C-C motif) receptor 1 0.814
Mmp9 matrix metallopeptidase 9 0.803
Kit kit oncogene 0.801
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.792
Ednrb endothelin receptor type B 0.759
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.758
Cd22 CD22 antigen 0.747
Gab1 growth factor receptor bound protein 2-associated protein 1 0.746
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.744
Ephb3 Eph receptor B3 0.737
Gli3 GLI-Kruppel family member GLI3 0.728
Smad3 MAD homolog 3 (Drosophila) 0.725
Ror1 receptor tyrosine kinase-like orphan receptor 1 0.724
Tlr4 toll-like receptor 4 0.684
Acvr1 activin A receptor, type 1 0.669
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.664
Il1r1 interleukin 1 receptor, type I 0.654
Epha4 Eph receptor A4 0.654
Prkce protein kinase C, epsilon 0.653
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.652
Fgfr2 fibroblast growth factor receptor 2 0.651
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.651
Fcgr2b Fc receptor, IgG, low affinity IIb 0.651
Vegfa vascular endothelial growth factor A 0.649
Smad6 MAD homolog 6 (Drosophila) 0.645
Dok1 docking protein 1 0.630
Cx3cr1 chemokine (C-X3-C) receptor 1 0.629
Grip1 glutamate receptor interacting protein 1 0.627
Gdnf glial cell line derived neurotrophic factor 0.617
Dok2 docking protein 2 0.611
Shc3 src homology 2 domain-containing transforming protein C3 0.607
Fzd8 frizzled homolog 8 (Drosophila) 0.598
Ccl2 chemokine (C-C motif) ligand 2 0.595
Il6st interleukin 6 signal transducer 0.588
Dab1 disabled homolog 1 (Drosophila) 0.578
Esr1 estrogen receptor 1 (alpha) 0.570
Notch1 Notch gene homolog 1 (Drosophila) 0.562
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.561
Apoe apolipoprotein E 0.545
C3ar1 complement component 3a receptor 1 0.513
Tgfbr2 transforming growth factor, beta receptor II 0.502
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.500
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.500
Ptk2 PTK2 protein tyrosine kinase 2 0.487
Nos2 nitric oxide synthase 2, inducible 0.484
Mapk8 mitogen-activated protein kinase 8 0.480
Nos3 nitric oxide synthase 3, endothelial cell 0.478
Irs1 insulin receptor substrate 1 0.475
Dvl1 dishevelled, dsh homolog 1 (Drosophila) 0.473
Apc adenomatosis polyposis coli 0.471
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.470
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.470
Ifng interferon gamma 0.463
Axin1 axin 1 0.454
Nr2f2 nuclear receptor subfamily 2, group F, member 2 0.452
Ccr2 chemokine (C-C motif) receptor 2 0.452
Klf3 Kruppel-like factor 3 (basic) 0.452
Dvl3 dishevelled 3, dsh homolog (Drosophila) 0.451
Trp53 transformation related protein 53 0.450
Cxcl13 chemokine (C-X-C motif) ligand 13 0.436
Ikzf1 IKAROS family zinc finger 1 0.433
Il10 interleukin 10 0.427
Igh immunoglobulin heavy chain complex 0.421
Fas Fas (TNF receptor superfamily member 6) 0.419
Tgfa transforming growth factor alpha 0.405
Cd79a CD79A antigen (immunoglobulin-associated alpha) 0.403
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
sur-2 Protein SUR-2 0.125
let-60 Protein LET-60 0.053
bar-1 Protein BAR-1 0.045
egl-18 Protein EGL-18 0.037
plc-3 Protein PLC-3 0.031
lin-25 Protein LIN-25 0.028
irx-1 Protein IRX-1 0.028
obr-3 Protein OBR-3 0.026
K10D6.4 Protein K10D6.4 0.024
lin-36 Protein LIN-36 0.023
pqn-62 Protein PQN-62 0.022
eor-2 Protein EOR-2 0.021
mek-2 Protein MEK-2 0.020
mpk-1 Protein MPK-1 0.019
CELE_F43G6.4 Protein F43G6.4 0.019
zoo-1 Protein ZOO-1 0.018
trim-9 Protein TRIM-9 0.018
rhgf-2 Protein RHGF-2 0.016
pry-1 Protein PRY-1 0.015
daf-19 Protein DAF-19 0.015
dpy-22 Protein DPY-22 0.015
lin-45 Protein LIN-45 0.015
csb-1 Protein CSB-1 0.014
zfp-3 Protein ZFP-3 0.014
nhr-6 Protein NHR-6 0.014
cdh-3 Protein CDH-3 0.014
kal-1 Protein KAL-1 0.014
elt-6 Protein ELT-6 0.012
R10E12.2 Protein R10E12.2 0.012
sax-7 Protein SAX-7 0.012
unc-129 Protein UNC-129 0.011
ham-1 Protein HAM-1 0.011
K10B3.6 Protein K10B3.6 0.011
fmi-1 Protein FMI-1 0.011
sma-6 Protein SMA-6 0.011
sel-2 Protein SEL-2 0.010
daf-15 Protein DAF-15 0.010
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Danio rerio
Name Description Probability Func Analog Organism
pdgfaa platelet-derived growth factor alpha a 0.850
nod1 nucleotide-binding oligomerization domain containing 1 0.689
sp2 sp2 transcription factor 0.523
crb2a crumbs homolog 2a 0.497
axin2 axin 2 (conductin, axil) 0.443
zgc:73359 zgc:73359 0.410
kdr kinase insert domain receptor (a type III receptor tyrosine kinase) 0.357
LOC566708 FL cytokine receptor-like 0.354
fzd7a frizzled homolog 7a 0.345
ghra growth hormone receptor a 0.339
ndr1 nodal-related 1 0.329
notch3 notch homolog 3 0.324
dvl3 dishevelled, dsh homolog 3 (Drosophila) 0.320
cx27.5 connexin 27.5 0.312
spry4 sprouty (Drosophila) homolog 4 0.308
erbb3b v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b 0.302
fgf17 fibroblast growth factor 17 0.295
tmpoa thymopoietin a 0.285
ephb4b eph receptor B4b 0.280
tgif1 TGFB-induced factor homeobox 1 0.280
igf1rb insulin-like growth factor 1b receptor 0.279
lef1 lymphocyte enhancer binding factor 1 0.275
smad9 MAD homolog 9 (Drosophila) 0.271
waca WW domain containing adaptor with coiled-coil a 0.259
LOC100151531 zinc finger protein Gfi-1b-like 0.252
epas1b endothelial PAS domain protein 1b 0.242
si:ch211-57k11.10 si:ch211-57k11.10 0.242
insra insulin receptor a 0.240
wnt8a wingless-type MMTV integration site family, member 8a 0.234
coro1a coronin, actin binding protein, 1A 0.233
bmp1a bone morphogenetic protein 1a 0.233
lyz lysozyme 0.229
cdh6 cadherin 6 0.222
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.221
nrarpa notch-regulated ankyrin repeat protein a 0.216
akap12b A kinase (PRKA) anchor protein (gravin) 12b 0.213
snai1b snail homolog 1b (Drosophila) 0.212
itgb1b integrin, beta 1b 0.210
nkx2.3 NK2 transcription factor related 3 0.208
rspo3 R-spondin 3 homolog (Xenopus laevis) 0.205
olig4 oligodendrocyte transcription factor 4 0.201
ghrb growth hormone receptor b 0.198
ncf1 neutrophil cytosolic factor 1 0.196
igf1 insulin-like growth factor 1 0.186
tnfsf10l tumor necrosis factor (ligand) superfamily, member 10 like 0.178
hhip hedgehog interacting protein 0.178
il17rd interleukin 17 receptor D 0.177
erbb3a v-erb-b2 erythroblastic leukemia viral oncogene homolog 3a 0.176
fgfr4 fibroblast growth factor receptor 4 0.175
vegfaa vascular endothelial growth factor Aa 0.175
igf1ra insulin-like growth factor 1a receptor 0.173
wnt10a wingless-type MMTV integration site family, member 10a 0.172
gnat1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 0.172
smad5 MAD homolog 5 (Drosophila) 0.171
rhoub ras homolog gene family, member Ub 0.170
prickle1a prickle-like 1 (Drosophila) a 0.168
csnk1g2a casein kinase 1, gamma 2a 0.165
ptena phosphatase and tensin homolog A 0.162
tie2 endothelium-specific receptor tyrosine kinase 2 0.162
ets1a v-ets erythroblastosis virus E26 oncogene homolog 1a 0.161
lama4 laminin, alpha 4 0.159
cyp1d1 cytochrome P450, family 1, subfamily D, polypeptide 1 0.155
oxtl oxytocin-like 0.155
zbtb4 zinc finger and BTB domain containing 4 0.155
wu:fv91b12 wu:fv91b12 0.155
vipr2 vasoactive intestinal peptide receptor 2 0.154
lft2 lefty2 0.154
ripk2 receptor-interacting serine-threonine kinase 2 0.152
ddt D-dopachrome tautomerase 0.150
insrb insulin receptor b 0.150
tob1a transducer of ERBB2, 1a 0.149
flh floating head 0.145
gro1 groucho 1 0.143
nkd1 naked cuticle homolog 1 (Drosophila) 0.142
lbr lamin B receptor 0.142
dvl2 dishevelled, dsh homolog 2 (Drosophila) 0.142
slc25a3a solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3a 0.141
wnt16 wingless-type MMTV integration site family, member 16 0.140
cfl2l cofilin 2, like 0.140
lhx2b LIM homeobox 2b 0.138
pias4a protein inhibitor of activated STAT, 4a 0.137
eomesa eomesodermin homolog a 0.135
rcv1 recoverin 0.134
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.132
rarga retinoic acid receptor gamma a 0.131
disp1 dispatched homolog 1 (Drosophila) 0.131
ggnbp2 gametogenetin binding protein 2 0.125
bmp2a bone morphogenetic protein 2a 0.125
pcsk5b proprotein convertase subtilisin/kexin type 5b 0.124
cdh23 cadherin-like 23 0.123
ndr2 nodal-related 2 0.123
mga MAX gene associated 0.122
furina furin (paired basic amino acid cleaving enzyme) a 0.122
urod uroporphyrinogen decarboxylase 0.120
nkx6.2 NK6 transcription factor related, locus 2 0.120
mfap4 microfibrillar-associated protein 4 0.120
tnfa tumor necrosis factor a (TNF superfamily, member 2) 0.119
smc1al structural maintenance of chromosomes 1A, like 0.119
gro2 groucho 2 0.119
fbp1b fructose-1,6-bisphosphatase 1b 0.119
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Drosophila melanogaster
Name Description Probability Func Analog Organism
bsk basket 0.163
hep hemipterous 0.159
dsh dishevelled 0.124
stck steamer duck 0.109
phl pole hole 0.093
rl rolled 0.068
dia diaphanous 0.044
aop anterior open 0.035
Jra Jun-related antigen 0.034
Rac1 CG2248 gene product from transcript CG2248-RA 0.034
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.033
Ras85D Ras oncogene at 85D 0.030
Rab5 Rab-protein 5 0.029
par-1 CG8201 gene product from transcript CG8201-RA 0.029
Akt1 CG4006 gene product from transcript CG4006-RA 0.027
S6k RPS6-p70-protein kinase 0.025
Dad Daughters against dpp 0.025
caz cabeza 0.025
spi spitz 0.024
babo baboon 0.023
Mad Mothers against dpp 0.022
Pten CG5671 gene product from transcript CG5671-RB 0.022
kay kayak 0.021
Smox Smad on X 0.021
CkIIalpha Casein kinase II alpha subunit 0.021
brat brain tumor 0.020
G-oalpha47A G protein oalpha 47A 0.020
Rac2 CG8556 gene product from transcript CG8556-RA 0.019
Cdc42 CG12530 gene product from transcript CG12530-RA 0.019
dm diminutive 0.018
yki yorkie 0.018
Atg1 Autophagy-specific gene 1 0.017
myoglianin CG1838 gene product from transcript CG1838-RD 0.016
Liprin-alpha CG11199 gene product from transcript CG11199-RB 0.015
dos daughter of sevenless 0.015
sd scalloped 0.014
sgl sugarless 0.014
Sara Smad anchor for receptor activation 0.014
Plc21C Phospholipase C at 21C 0.014
pyd polychaetoid 0.014
pan pangolin 0.013
htl heartless 0.013
tkv thickveins 0.012
lqf liquid facets 0.012
WASp CG1520 gene product from transcript CG1520-RA 0.012
stumps CG31317 gene product from transcript CG31317-RC 0.012
eya eyes absent 0.011
Pkn Protein kinase related to protein kinase N 0.011
Gug Grunge 0.011
chico CG5686 gene product from transcript CG5686-RB 0.011
aux auxillin 0.010
puc puckered 0.010
smo smoothened 0.010
CG31048 CG31048 gene product from transcript CG31048-RB 0.010
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Homo sapiens
Name Description Probability Func Analog Organism
EGFR epidermal growth factor receptor 1.000
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.000
GRB2 growth factor receptor-bound protein 2 1.000
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 1.000
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 1.000
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 1.000
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.000
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.000
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.000
PLCG1 phospholipase C, gamma 1 1.000
FGFR2 fibroblast growth factor receptor 2 0.999
FGF1 fibroblast growth factor 1 (acidic) 0.999
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.999
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.999
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.999
FGFR1 fibroblast growth factor receptor 1 0.998
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.998
MET met proto-oncogene (hepatocyte growth factor receptor) 0.997
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.997
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.996
IGF1R insulin-like growth factor 1 receptor 0.995
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.991
TGFB1 transforming growth factor, beta 1 0.989
LAT linker for activation of T cells 0.988
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.985
LRRK2 leucine-rich repeat kinase 2 0.982
GAB1 GRB2-associated binding protein 1 0.982
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.981
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.981
SOS1 son of sevenless homolog 1 (Drosophila) 0.979
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.977
TRAF2 TNF receptor-associated factor 2 0.976
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.975
CAV1 caveolin 1, caveolae protein, 22kDa 0.974
VEGFA vascular endothelial growth factor A 0.973
BBS10 Bardet-Biedl syndrome 10 0.969
TRAF5 TNF receptor-associated factor 5 0.965
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 0.960
FLNA filamin A, alpha 0.957
MYD88 myeloid differentiation primary response gene (88) 0.952
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.946
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.944
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.940
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.937
IRS1 insulin receptor substrate 1 0.937
MAPK8 mitogen-activated protein kinase 8 0.937
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.934
SYK spleen tyrosine kinase 0.927
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.922
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.920
DAB2 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) 0.913
NRP1 neuropilin 1 0.908
CSNK1E casein kinase 1, epsilon 0.900
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.896
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.888
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 0.875
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.871
SMAD3 SMAD family member 3 0.870
BMPR1A bone morphogenetic protein receptor, type IA 0.843
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.837
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 0.834
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.829
NCK1 NCK adaptor protein 1 0.826
INSR insulin receptor 0.826
APP amyloid beta (A4) precursor protein 0.825
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.798
BCAR1 breast cancer anti-estrogen resistance 1 0.792
CFLAR CASP8 and FADD-like apoptosis regulator 0.788
GAB2 GRB2-associated binding protein 2 0.784
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.783
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 0.773
CD40 CD40 molecule, TNF receptor superfamily member 5 0.764
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.762
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 0.759
FN1 fibronectin 1 0.758
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.739
MAP3K1 mitogen-activated protein kinase kinase kinase 1 0.733
TRAF6 TNF receptor-associated factor 6 0.731
FYN FYN oncogene related to SRC, FGR, YES 0.728
VAV1 vav 1 guanine nucleotide exchange factor 0.724
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.723
LRP6 low density lipoprotein receptor-related protein 6 0.712
MAP2K7 mitogen-activated protein kinase kinase 7 0.711
IRAK2 interleukin-1 receptor-associated kinase 2 0.700
IQGAP1 IQ motif containing GTPase activating protein 1 0.699
ENG endoglin 0.698
MAPK14 mitogen-activated protein kinase 14 0.693
FLNB filamin B, beta 0.691
FSTL1 follistatin-like 1 0.686
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.677
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.671
JAK2 Janus kinase 2 0.661
MPDZ multiple PDZ domain protein 0.650
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.646
ABI1 abl-interactor 1 0.641
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.636
TNF tumor necrosis factor 0.628
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.616
IL1R1 interleukin 1 receptor, type I 0.607
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.605
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Rattus norvegicus
Name Description Probability Func Analog Organism
Ptafr platelet-activating factor receptor 0.398
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.256
Hpcal4 hippocalcin-like 4 0.144
RGD1304644 similar to RIKEN cDNA 2310046K01 0.144
Calcrl calcitonin receptor-like 0.144
Csn1s1 casein alpha s1 0.134
Tgfbr2 transforming growth factor, beta receptor II 0.133
Inpp5d inositol polyphosphate-5-phosphatase D 0.121
Epas1 endothelial PAS domain protein 1 0.120
RGD1564664 similar to LOC387763 protein 0.120
Irs1 insulin receptor substrate 1 0.117
Elf1 E74-like factor 1 0.116
Ar androgen receptor 0.114
Fgfr2 fibroblast growth factor receptor 2 0.114
Ptp4a2 protein tyrosine phosphatase 4a2 0.112
Met met proto-oncogene 0.108
RT1-Db1 RT1 class II, locus Db1 0.104
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.103
Sox17 SRY (sex determining region Y)-box 17 0.099
Sstr5 somatostatin receptor 5 0.099
Chrng cholinergic receptor, nicotinic, gamma 0.098
Il2rg interleukin 2 receptor, gamma 0.093
Ednrb endothelin receptor type B 0.091
Il1a interleukin 1 alpha 0.090
Sirpa signal-regulatory protein alpha 0.087
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.086
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.083
Mprip myosin phosphatase Rho interacting protein 0.080
Slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 0.079
Cd38 CD38 molecule 0.079
Mpeg1 macrophage expressed 1 0.078
Ccnd3 cyclin D3 0.078
Dock8 dedicator of cytokinesis 8 0.078
Prkch protein kinase C, eta 0.078
Prkcd protein kinase C, delta 0.075
LOC100363783 rCG53773-like 0.075
Usf2 upstream transcription factor 2, c-fos interacting 0.072
Homer1 homer homolog 1 (Drosophila) 0.070
Dchs1 dachsous 1 (Drosophila) 0.070
Cbl Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.070
Cxcr4 chemokine (C-X-C motif) receptor 4 0.069
Gzmk granzyme K 0.068
Smad7 SMAD family member 7 0.066
Mr1 major histocompatibility complex, class I-related 0.066
Fmnl1 formin-like 1 0.064
Myh9 myosin, heavy chain 9, non-muscle 0.063
Hck hemopoietic cell kinase 0.063
Cd37 CD37 molecule 0.061
Tlr4 toll-like receptor 4 0.061
Notch2 Notch homolog 2 (Drosophila) 0.060
Rorb RAR-related orphan receptor B 0.059
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.059
RGD1564327 similar to integrin alpha 8 0.059
Ednra endothelin receptor type A 0.059
Oprk1 opioid receptor, kappa 1 0.059
Fgf7 fibroblast growth factor 7 0.058
Adora2a adenosine A2a receptor 0.058
Vav1 vav 1 guanine nucleotide exchange factor 0.053
Rgs14 regulator of G-protein signaling 14 0.053
Map3k1 mitogen activated protein kinase kinase kinase 1 0.053
Hcrtr1 hypocretin (orexin) receptor 1 0.053
Hbe1 hemoglobin, epsilon 1 0.051
Slc1a3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.051
Foxe3 forkhead box E3 0.051
Trhr thyrotropin releasing hormone receptor 0.050
Itpkb inositol 1,4,5-trisphosphate 3-kinase B 0.050
Gja1 gap junction protein, alpha 1 0.050
Agtr1a angiotensin II receptor, type 1a 0.049
Pyy peptide YY (mapped) 0.048
Grb2 growth factor receptor bound protein 2 0.048
Rhog ras homolog gene family, member G (rho G) 0.048
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.047
Itm2b integral membrane protein 2B 0.047
Ptprq protein tyrosine phosphatase, receptor type, Q 0.047
Ocln occludin 0.047
Adam17 ADAM metallopeptidase domain 17 0.047
Ets1 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) 0.046
Jak1 Janus kinase 1 0.046
Psg29 pregnancy-specific glycoprotein 29 0.046
Cdc34 cell division cycle 34 homolog (S. cerevisiae) 0.045
Bcl2 B-cell CLL/lymphoma 2 0.045
Mybphl myosin binding protein H-like 0.045
Efnb1 ephrin B1 0.045
Mapk14 mitogen activated protein kinase 14 0.045
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.045
Insr insulin receptor 0.044
Pip4k2b phosphatidylinositol-5-phosphate 4-kinase, type II, beta 0.044
Olr857 olfactory receptor 857 0.044
Gucy2d guanylate cyclase 2d 0.044
Anxa5 annexin A5 0.043
Fgf23 fibroblast growth factor 23 0.042
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.042
Svs1 seminal vesicle secretory protein 1 0.042
Fgfr1 Fibroblast growth factor receptor 1 0.041
Homer3 homer homolog 3 (Drosophila) 0.041
Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 0.040
Utrn utrophin 0.040
Ccnd2 cyclin D2 0.039
Ltbp2 latent transforming growth factor beta binding protein 2 0.039
Adrbk1 adrenergic, beta, receptor kinase 1 0.039
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism