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Process View

Mus musculus

26 genes annotated in mouse

centrosome organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "centrosome organization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "centrosome organization" (in gray)

Name	Description	Probability	Func Analog Organism
Cdc25c	cell division cycle 25 homolog C (S. pombe)	0.936	Fly
Pafah1b1	platelet-activating factor acetylhydrolase, isoform 1b, subunit 1	0.924	Worm Fly
Brca1	breast cancer 1	0.887
Wdhd1	WD repeat and HMG-box DNA binding protein 1	0.659
Kif2c	kinesin family member 2C	0.628	Fly
Plk4	polo-like kinase 4 (Drosophila)	0.561
Rpgrip1l	Rpgrip1-like	0.551
Kif4	kinesin family member 4	0.551
Lmnb1	lamin B1	0.547	Fly
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	0.532	Fly
Hspa8	heat shock protein 8	0.517
Cdc7	cell division cycle 7 (S. cerevisiae)	0.512
Dtl	denticleless homolog (Drosophila)	0.454
Trp53	transformation related protein 53	0.426
Spag5	sperm associated antigen 5	0.404
Ccnb1	cyclin B1	0.392
Rad51ap1	RAD51 associated protein 1	0.386
Mis18bp1	MIS18 binding protein 1	0.378
Racgap1	Rac GTPase-activating protein 1	0.347	Fly
Dlgap5	discs, large (Drosophila) homolog-associated protein 5	0.341
Anln	anillin, actin binding protein	0.334
Rpl7a	ribosomal protein L7A	0.329
Stil	Scl/Tal1 interrupting locus	0.322
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.311
Plk1	polo-like kinase 1 (Drosophila)	0.288	Human Worm Fly
Smc2	structural maintenance of chromosomes 2	0.286
C330027C09Rik	RIKEN cDNA C330027C09 gene	0.257
Sass6	spindle assembly 6 homolog (C. elegans)	0.247	Fly
Bub1	budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)	0.208
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.202
Cdca5	cell division cycle associated 5	0.182
Bbs2	Bardet-Biedl syndrome 2 (human)	0.167
Ccna2	cyclin A2	0.160
Kif20a	kinesin family member 20A	0.157
Rps7	ribosomal protein S7	0.150
Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2	0.149	Human
Prc1	protein regulator of cytokinesis 1	0.148	Fly
Kif11	kinesin family member 11	0.147
Brca2	breast cancer 2	0.144	Human
Blm	Bloom syndrome, RecQ helicase-like	0.143
Ndel1	nuclear distribution gene E-like homolog 1 (A. nidulans)	0.127
Gtse1	G two S phase expressed protein 1	0.117
Apc	adenomatosis polyposis coli	0.111
Ttk	Ttk protein kinase	0.111
Zfr	zinc finger RNA binding protein	0.109
Atm	ataxia telangiectasia mutated homolog (human)	0.102
Aurkb	aurora kinase B	0.100	Fly
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.100
Hmmr	hyaluronan mediated motility receptor (RHAMM)	0.099
Ccnf	cyclin F	0.098	Human
Iqgap3	IQ motif containing GTPase activating protein 3	0.097
Mdm2	transformed mouse 3T3 cell double minute 2	0.088
Cdc25a	cell division cycle 25 homolog A (S. pombe)	0.086	Fly
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.085
Aurka	aurora kinase A	0.082
Tmpo	thymopoietin	0.078
Smc4	structural maintenance of chromosomes 4	0.075
Kif2a	kinesin family member 2A	0.074	Fly
Cenpn	centromere protein N	0.072
Bod1l	biorientation of chromosomes in cell division 1-like	0.072
Incenp	inner centromere protein	0.071
Mcm3	minichromosome maintenance deficient 3 (S. cerevisiae)	0.071
Kif23	kinesin family member 23	0.070	Fly
Exo1	exonuclease 1	0.068
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.064
H2afx	H2A histone family, member X	0.064
Ccnb2	cyclin B2	0.064
Cdc25b	cell division cycle 25 homolog B (S. pombe)	0.062	Fly
E2f8	E2F transcription factor 8	0.061
Sun1	Sad1 and UNC84 domain containing 1	0.061
Stag1	stromal antigen 1	0.059
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.057
Ndc80	NDC80 homolog, kinetochore complex component (S. cerevisiae)	0.056
Fam64a	family with sequence similarity 64, member A	0.056
Tacc3	transforming, acidic coiled-coil containing protein 3	0.056
Gsg2	germ cell-specific gene 2	0.055
Sgol1	shugoshin-like 1 (S. pombe)	0.055
Cdt1	chromatin licensing and DNA replication factor 1	0.055	Fly
Mastl	microtubule associated serine/threonine kinase-like	0.052
Mxd3	Max dimerization protein 3	0.051
Mgea5	meningioma expressed antigen 5 (hyaluronidase)	0.051
Mybl2	myeloblastosis oncogene-like 2	0.051	Fly
1110004F10Rik	RIKEN cDNA 1110004F10 gene	0.051
Tpr	translocated promoter region	0.050
Recql	RecQ protein-like	0.049
Trip13	thyroid hormone receptor interactor 13	0.048
Ckap2	cytoskeleton associated protein 2	0.047
Cdca8	cell division cycle associated 8	0.046
Trim59	tripartite motif-containing 59	0.045
Slbp	stem-loop binding protein	0.042
Rplp0	ribosomal protein, large, P0	0.042
Eif4g1	eukaryotic translation initiation factor 4, gamma 1	0.041
Smc6	structural maintenance of chromosomes 6	0.041
Cep55	centrosomal protein 55	0.040
Ccdc99	coiled-coil domain containing 99	0.040
Eif5a	eukaryotic translation initiation factor 5A	0.040
Pola1	polymerase (DNA directed), alpha 1	0.039
Bub1b	budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)	0.039
Cenpf	centromere protein F	0.039
Scaf11	SR-related CTD-associated factor 11	0.039
Paip2	polyadenylate-binding protein-interacting protein 2	0.038
Fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.038
Chordc1	cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1	0.038
Wrn	Werner syndrome homolog (human)	0.037
Ncaph	non-SMC condensin I complex, subunit H	0.036
Htt	huntingtin	0.035
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.034
Rfc1	replication factor C (activator 1) 1	0.034
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.033
Eme1	essential meiotic endonuclease 1 homolog 1 (S. pombe)	0.033
Rasa1	RAS p21 protein activator 1	0.033
Lmnb2	lamin B2	0.033	Fly
Gen1	Gen homolog 1, endonuclease (Drosophila)	0.031	Human
Mpp5	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	0.030
Rpgr	retinitis pigmentosa GTPase regulator	0.030
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.030
Cul3	cullin 3	0.030
Ube2b	ubiquitin-conjugating enzyme E2B, RAD6 homology (S. cerevisiae)	0.030	Fly
Zfp62	zinc finger protein 62	0.029
Mns1	meiosis-specific nuclear structural protein 1	0.028
Ptma	prothymosin alpha	0.028
Birc5	baculoviral IAP repeat-containing 5	0.028
Pkn2	protein kinase N2	0.027
Lin9	lin-9 homolog (C. elegans)	0.027
Asf1b	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.026
Foxm1	forkhead box M1	0.026
Arhgap21	Rho GTPase activating protein 21	0.026
Strn3	striatin, calmodulin binding protein 3	0.026
Akt1	thymoma viral proto-oncogene 1	0.026
Cdk1	cyclin-dependent kinase 1	0.025
Ahi1	Abelson helper integration site 1	0.025
Ywhae	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.025
Cenpe	centromere protein E	0.025
Eif3a	eukaryotic translation initiation factor 3, subunit A	0.024
Xpo1	exportin 1, CRM1 homolog (yeast)	0.024
Wee1	WEE 1 homolog 1 (S. pombe)	0.024	Fly
Macf1	microtubule-actin crosslinking factor 1	0.023
Ube2c	ubiquitin-conjugating enzyme E2C	0.023
Msh2	mutS homolog 2 (E. coli)	0.023
Rsrc2	arginine/serine-rich coiled-coil 2	0.022
Cbx5	chromobox homolog 5 (Drosophila HP1a)	0.022
Map4k5	mitogen-activated protein kinase kinase kinase kinase 5	0.022
Fancm	Fanconi anemia, complementation group M	0.022
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.022
Hnrnpu	heterogeneous nuclear ribonucleoprotein U	0.022
Arid4b	AT rich interactive domain 4B (RBP1-like)	0.022
Zfand5	zinc finger, AN1-type domain 5	0.022
Lancl2	LanC (bacterial lantibiotic synthetase component C)-like 2	0.021
Diap3	diaphanous homolog 3 (Drosophila)	0.021
Top2a	topoisomerase (DNA) II alpha	0.021
Psmd8	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8	0.021
Rbl1	retinoblastoma-like 1 (p107)	0.021
Cenpa	centromere protein A	0.020
Etaa1	Ewing's tumor-associated antigen 1	0.020
Nup50	nucleoporin 50	0.020
Cdkn3	cyclin-dependent kinase inhibitor 3	0.020
Mdm1	transformed mouse 3T3 cell double minute 1	0.020
Bbs1	Bardet-Biedl syndrome 1 (human)	0.020
Ect2	ect2 oncogene	0.020
Trip12	thyroid hormone receptor interactor 12	0.020
Tcp1	t-complex protein 1	0.020
Thbs1	thrombospondin 1	0.020
Nde1	nuclear distribution gene E homolog 1 (A nidulans)	0.019
Brsk1	BR serine/threonine kinase 1	0.019
Ift80	intraflagellar transport 80 homolog (Chlamydomonas)	0.019
Rab10	RAB10, member RAS oncogene family	0.019
Psip1	PC4 and SFRS1 interacting protein 1	0.019
Baz1b	bromodomain adjacent to zinc finger domain, 1B	0.019
Taf4a	TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.018
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.018
Cdc6	cell division cycle 6 homolog (S. cerevisiae)	0.018
Nedd1	neural precursor cell expressed, developmentally down-regulated gene 1	0.018	Fly
Vbp1	von Hippel-Lindau binding protein 1	0.018
Ccne1	cyclin E1	0.018
Banf1	barrier to autointegration factor 1	0.017
Mdm4	transformed mouse 3T3 cell double minute 4	0.017
Hspa4l	heat shock protein 4 like	0.017
Aspm	asp (abnormal spindle)-like, microcephaly associated (Drosophila)	0.017	Fly
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.017
Rplp1	ribosomal protein, large, P1	0.017
Pde7a	phosphodiesterase 7A	0.017
Cacybp	calcyclin binding protein	0.017
Hcfc1	host cell factor C1	0.017
Trak2	trafficking protein, kinesin binding 2	0.017
Usp1	ubiquitin specific peptidase 1	0.017
Sec24b	Sec24 related gene family, member B (S. cerevisiae)	0.017
Med23	mediator complex subunit 23	0.016
Mphosph9	M-phase phosphoprotein 9	0.016
Haus5	HAUS augmin-like complex, subunit 5	0.016
Wdr26	WD repeat domain 26	0.016
Zranb2	zinc finger, RAN-binding domain containing 2	0.016
Rab5a	RAB5A, member RAS oncogene family	0.016
Nf2	neurofibromatosis 2	0.016
Ipo5	importin 5	0.016
Rpl10a	ribosomal protein L10A	0.016
Ppp2r2a	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform	0.016
Chek2	CHK2 checkpoint homolog (S. pombe)	0.016
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.016
Cct5	chaperonin containing Tcp1, subunit 5 (epsilon)	0.016
Cdca7l	cell division cycle associated 7 like	0.016
Tcerg1	transcription elongation regulator 1 (CA150)	0.016
Pole2	polymerase (DNA directed), epsilon 2 (p59 subunit)	0.016
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.016
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.016
Mcm2	minichromosome maintenance deficient 2 mitotin (S. cerevisiae)	0.016
Naca	nascent polypeptide-associated complex alpha polypeptide	0.016
Hnrnph3	heterogeneous nuclear ribonucleoprotein H3	0.016
Kif22	kinesin family member 22	0.016
Rock1	Rho-associated coiled-coil containing protein kinase 1	0.015	Mouse
Dbf4	DBF4 homolog (S. cerevisiae)	0.015
Kif5c	kinesin family member 5C	0.015	Fly
Sin3a	transcriptional regulator, SIN3A (yeast)	0.015
Skil	SKI-like	0.015
Ptgs2	prostaglandin-endoperoxide synthase 2	0.015
Tsc2	tuberous sclerosis 2	0.015
Ckap5	cytoskeleton associated protein 5	0.015	Human
Prkci	protein kinase C, iota	0.015
Nphp1	nephronophthisis 1 (juvenile) homolog (human)	0.015
Smap1	stromal membrane-associated protein 1	0.015
Capzb	capping protein (actin filament) muscle Z-line, beta	0.014
Kit	kit oncogene	0.014
Nbn	nibrin	0.014
Pum2	pumilio 2 (Drosophila)	0.014
Orc2	origin recognition complex, subunit 2	0.014
Ranbp9	RAN binding protein 9	0.014
Brsk2	BR serine/threonine kinase 2	0.014	Mouse
Rrm1	ribonucleotide reductase M1	0.014
4930427A07Rik	RIKEN cDNA 4930427A07 gene	0.014
Topbp1	topoisomerase (DNA) II binding protein 1	0.014
Gtf2i	general transcription factor II I	0.014
Naa35	N(alpha)-acetyltransferase 35, NatC auxiliary subunit	0.014
6330503K22Rik	RIKEN cDNA 6330503K22 gene	0.014
Rps19	ribosomal protein S19	0.014
Zfp617	zinc finger protein 617	0.014
Odf2	outer dense fiber of sperm tails 2	0.014
Fbn1	fibrillin 1	0.014
Rbm15	RNA binding motif protein 15	0.014
Dsn1	DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)	0.013
Casc5	cancer susceptibility candidate 5	0.013
Top2b	topoisomerase (DNA) II beta	0.013
Mkks	McKusick-Kaufman syndrome protein	0.013
Dctn1	dynactin 1	0.013
Kif16b	kinesin family member 16B	0.013
Atf2	activating transcription factor 2	0.013
Mcm10	minichromosome maintenance deficient 10 (S. cerevisiae)	0.013
Gmnn	geminin	0.013
Zfml	zinc finger, matrin-like	0.013
2610027L16Rik	RIKEN cDNA 2610027L16 gene	0.013
Rabep1	rabaptin, RAB GTPase binding effector protein 1	0.013
Chaf1b	chromatin assembly factor 1, subunit B (p60)	0.013
Stk11	serine/threonine kinase 11	0.013
Kif5a	kinesin family member 5A	0.013	Fly
Lmna	lamin A	0.013	Fly
Ncoa6	nuclear receptor coactivator 6	0.013
Rpl11	ribosomal protein L11	0.013
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.012
Nek8	NIMA (never in mitosis gene a)-related expressed kinase 8	0.012
Spna1	spectrin alpha 1	0.012
Hjurp	Holliday junction recognition protein	0.012
4930534B04Rik	RIKEN cDNA 4930534B04 gene	0.012
Fancd2	Fanconi anemia, complementation group D2	0.012
Dynll1	dynein light chain LC8-type 1	0.012
Smn1	survival motor neuron 1	0.012
Slk	STE20-like kinase (yeast)	0.012
Sae1	SUMO1 activating enzyme subunit 1	0.012
Myef2	myelin basic protein expression factor 2, repressor	0.012
Dusp1	dual specificity phosphatase 1	0.012
Zfx	zinc finger protein X-linked	0.012
Fbxw7	F-box and WD-40 domain protein 7	0.012
Ywhaq	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.012
Dnm1l	dynamin 1-like	0.012
Hsph1	heat shock 105kDa/110kDa protein 1	0.012
Rad50	RAD50 homolog (S. cerevisiae)	0.012
Tcra	T-cell receptor alpha chain	0.012
Iqcb1	IQ calmodulin-binding motif containing 1	0.012
Invs	inversin	0.012
Add1	adducin 1 (alpha)	0.011	Fly
Ska1	spindle and kinetochore associated complex subunit 1	0.011
Jak2	Janus kinase 2	0.011
Runx1	runt related transcription factor 1	0.011
Parp2	poly (ADP-ribose) polymerase family, member 2	0.011
Rps15a	ribosomal protein S15A	0.011
Sumo2	SMT3 suppressor of mif two 3 homolog 2 (yeast)	0.011
Cks2	CDC28 protein kinase regulatory subunit 2	0.011
Phtf1	putative homeodomain transcription factor 1	0.011
Skp1a	S-phase kinase-associated protein 1A	0.011
Arl6	ADP-ribosylation factor-like 6	0.011
Cdca2	cell division cycle associated 2	0.011
Bclaf1	BCL2-associated transcription factor 1	0.011
Fam83d	family with sequence similarity 83, member D	0.011
Rad18	RAD18 homolog (S. cerevisiae)	0.011
Dyrk1a	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a	0.011
Golga4	golgi autoantigen, golgin subfamily a, 4	0.011
Gsk3b	glycogen synthase kinase 3 beta	0.011
Ncapd2	non-SMC condensin I complex, subunit D2	0.011
Kif3a	kinesin family member 3A	0.011
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.011
4632434I11Rik	RIKEN cDNA 4632434I11 gene	0.011
Etnk1	ethanolamine kinase 1	0.011
Bax	BCL2-associated X protein	0.011
Nusap1	nucleolar and spindle associated protein 1	0.011
Gna13	guanine nucleotide binding protein, alpha 13	0.011
Sf3b2	splicing factor 3b, subunit 2	0.010
Akt3	thymoma viral proto-oncogene 3	0.010
Rpl18	ribosomal protein L18	0.010
Arfgef1	ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)	0.010
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.010	Fly
Ctcf	CCCTC-binding factor	0.010
Caprin2	caprin family member 2	0.010
Asap1	ArfGAP with SH# domain, ankyrin repeat and PH domain1	0.010
Cep290	centrosomal protein 290	0.010
Aqr	aquarius	0.010
Ckap2l	cytoskeleton associated protein 2-like	0.010
Nae1	NEDD8 activating enzyme E1 subunit 1	0.010
Ccdc77	coiled-coil domain containing 77	0.010
Cep57l1	centrosomal protein 57-like 1	0.010
Oaz2-ps	ornithine decarboxylase antizyme 2, pseudogene	0.010
Mier3	mesoderm induction early response 1, family member 3	0.010
Bzw1	basic leucine zipper and W2 domains 1	0.010
Eri2	exoribonuclease 2	0.010
2610039C10Rik	RIKEN cDNA 2610039C10 gene	0.010