The network for 'apoptotic signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

apoptotic signaling pathway

A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.

Mus musculus
Name Description Probability Func Analog Organism
Pten phosphatase and tensin homolog 1.000
Ctnnb1 catenin (cadherin associated protein), beta 1 1.000
Trp53 transformation related protein 53 0.999
Mdm2 transformed mouse 3T3 cell double minute 2 0.999
Fas Fas (TNF receptor superfamily member 6) 0.996
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.991
Tnf tumor necrosis factor 0.990
Rb1 retinoblastoma 1 0.987
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.985
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.985
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.980
Lepr leptin receptor 0.972
Bcl2 B-cell leukemia/lymphoma 2 0.968
Tgfb1 transforming growth factor, beta 1 0.965
Brca1 breast cancer 1 0.965
Rnf2 ring finger protein 2 0.960
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.960
Casp8 caspase 8 0.960
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.958
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.946
Ikzf1 IKAROS family zinc finger 1 0.942
Stk4 serine/threonine kinase 4 0.933
Tlr4 toll-like receptor 4 0.926
Ptgs2 prostaglandin-endoperoxide synthase 2 0.923
Vegfa vascular endothelial growth factor A 0.922
Ikbkb inhibitor of kappaB kinase beta 0.921
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.920
Gdnf glial cell line derived neurotrophic factor 0.919
Runx1 runt related transcription factor 1 0.919
Igh immunoglobulin heavy chain complex 0.917
Nos3 nitric oxide synthase 3, endothelial cell 0.915
Col1a1 collagen, type I, alpha 1 0.914
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.910
Rbl1 retinoblastoma-like 1 (p107) 0.900
Tcf21 transcription factor 21 0.893
Icos inducible T-cell co-stimulator 0.888
Itgal integrin alpha L 0.884
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.879
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.874
Casp3 caspase 3 0.870
Cd28 CD28 antigen 0.870
Ncoa3 nuclear receptor coactivator 3 0.867
Il2rb interleukin 2 receptor, beta chain 0.857
Tcf7l2 transcription factor 7-like 2, T-cell specific, HMG-box 0.854
Msh2 mutS homolog 2 (E. coli) 0.847
Atm ataxia telangiectasia mutated homolog (human) 0.846
Ntf3 neurotrophin 3 0.845
Traf6 TNF receptor-associated factor 6 0.835
Ifng interferon gamma 0.834
Acvr1 activin A receptor, type 1 0.833
Fasl Fas ligand (TNF superfamily, member 6) 0.822
Cdkn2d cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 0.821
Cd4 CD4 antigen 0.814
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.813
Mmp9 matrix metallopeptidase 9 0.807
Skil SKI-like 0.804
Nos1 nitric oxide synthase 1, neuronal 0.793
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.792
Ikbkg inhibitor of kappaB kinase gamma 0.790
Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 0.790
E2f1 E2F transcription factor 1 0.788
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.787
Hmgb1 high mobility group box 1 0.786
Trp63 transformation related protein 63 0.786
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.779
Bax BCL2-associated X protein 0.779
Myc myelocytomatosis oncogene 0.777
Gpr132 G protein-coupled receptor 132 0.767
Casp1 caspase 1 0.765
Lbr lamin B receptor 0.764
Amh anti-Mullerian hormone 0.764
Sharpin SHANK-associated RH domain interacting protein 0.762
Cd151 CD151 antigen 0.749
Vhl von Hippel-Lindau tumor suppressor 0.745
Inhba inhibin beta-A 0.744
Nfatc3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.744
Hoxd13 homeobox D13 0.743
Krt17 keratin 17 0.742
Nos2 nitric oxide synthase 2, inducible 0.734
Il2rg interleukin 2 receptor, gamma chain 0.729
Thbs1 thrombospondin 1 0.726
Bcl2l1 BCL2-like 1 0.721
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.721
Fst follistatin 0.712
Sh2d2a SH2 domain protein 2A 0.708
Mapk8 mitogen-activated protein kinase 8 0.705
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.703
Apc adenomatosis polyposis coli 0.701
Cdk4 cyclin-dependent kinase 4 0.698
Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.696
Fyn Fyn proto-oncogene 0.695
Plcg1 phospholipase C, gamma 1 0.692
Ar androgen receptor 0.689
Tgfbr2 transforming growth factor, beta receptor II 0.688
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.684
Rxra retinoid X receptor alpha 0.680
Ldb3 LIM domain binding 3 0.680
Lck lymphocyte protein tyrosine kinase 0.675
Itgb3 integrin beta 3 0.673
Wwox WW domain-containing oxidoreductase 0.669
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
sma-6 Protein SMA-6 0.017
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Danio rerio
Name Description Probability Func Analog Organism
fgfr1a fibroblast growth factor receptor 1a 0.409
dct dopachrome tautomerase 0.347
tnfrsfa tumor necrosis factor receptor superfamily, member a 0.221
gpr126 G protein-coupled receptor 126 0.214
nrg2a neuregulin 2a 0.192
evx1 even-skipped homeobox 1 0.185
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.168
ptgs2a prostaglandin-endoperoxide synthase 2a 0.153
rag1 recombination activating gene 1 0.151
wnt11r wingless-type MMTV integration site family, member 11, related 0.149
tagln2 transgelin 2 0.148
efna5a ephrin A5a 0.143
fgf3 fibroblast growth factor 3 0.137
nf1a neurofibromin 1a 0.130
cnn2 calponin 2 0.126
egr1 early growth response 1 0.125
lhx2b LIM homeobox 2b 0.117
bcl2l1 bcl2-like 1 0.107
plcg1 phospholipase C, gamma 1 0.096
myod1 myogenic differentiation 1 0.095
ptgs1 prostaglandin-endoperoxide synthase 1 0.093
pcdh18b protocadherin 18b 0.092
mll myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.088
boc brother of CDO 0.086
nap1l1 nucleosome assembly protein 1, like 1 0.085
faua Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed a 0.085
stc1l stanniocalcin 1, like 0.084
igf1 insulin-like growth factor 1 0.084
krt4 keratin 4 0.083
bnip3lb BCL2/adenovirus E1B interacting protein 3-like b 0.079
brd2a bromodomain-containing 2a 0.076
ptf1a pancreas specific transcription factor, 1a 0.074
trpv6 transient receptor potential cation channel, subfamily V, member 6 0.073
nrg1 neuregulin 1 0.071
atoh1a atonal homolog 1a 0.071
mmp9 matrix metalloproteinase 9 0.069
ywhabl tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like 0.067
baxa bcl2-associated X protein, a 0.066
pea3 ETS-domain transcription factor pea3 0.064
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.064
gnb2l1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 0.063
id3 inhibitor of DNA binding 3 0.063
rhoab ras homolog gene family, member Ab 0.063
ncor1 nuclear receptor co-repressor 1 0.063
tnfsf10l tumor necrosis factor (ligand) superfamily, member 10 like 0.062
pitx3 paired-like homeodomain transcription factor 3 0.059
psen1 presenilin 1 0.058
tm9sf2 transmembrane 9 superfamily member 2 0.056
igf1ra insulin-like growth factor 1a receptor 0.055
gro1 groucho 1 0.055
pob partial optokinetic response b 0.055
dlx6a distal-less homeobox gene 6a 0.055
tgif1 TGFB-induced factor homeobox 1 0.054
mapk3 mitogen-activated protein kinase 3 0.054
ptges prostaglandin E synthase 0.052
met met proto-oncogene (hepatocyte growth factor receptor) 0.052
si:ch211-215h6.2 si:ch211-215h6.2 0.052
vegfc vascular endothelial growth factor c 0.052
csrnp1b cysteine-serine-rich nuclear protein 1b 0.051
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.050
cdkn1a cyclin-dependent kinase inhibitor 1A 0.050
sgk1 serum/glucocorticoid regulated kinase 1 0.050
lef1 lymphocyte enhancer binding factor 1 0.049
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.048
gfer growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae) 0.048
gsc goosecoid 0.047
erbb3b v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b 0.046
fn1 fibronectin 1 0.046
zgc:101724 zgc:101724 0.045
ntn2 netrin 2 0.045
eif3ha eukaryotic translation initiation factor 3, subunit H, a 0.045
inhbaa inhibin, beta Aa 0.044
wnt4a wingless-type MMTV integration site family, member 4a 0.044
rarga retinoic acid receptor gamma a 0.043
mmp2 matrix metalloproteinase 2 0.043
jag2 jagged 2 0.042
erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog 0.041
tgfb3 transforming growth factor, beta 3 0.040
nr1h3 nuclear receptor subfamily 1, group H, member 3 0.040
cmyb transcription factor cmyb 0.040
kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.040
gnb1a guanine nucleotide binding protein (G protein), beta polypeptide 1a 0.039
bmpr1ba bone morphogenetic protein receptor, type 1ba 0.039
foxa3 forkhead box A3 0.039
pknox1.1 pbx/knotted 1 homeobox 1.1 0.038
alas2 aminolevulinate, delta-, synthetase 2 0.038
ube2g2 ubiquitin-conjugating enzyme E2G 2 0.037
fzd7a frizzled homolog 7a 0.036
timp2a tissue inhibitor of metalloproteinase 2a 0.036
rpl5b ribosomal protein L5b 0.036
msna moesin a 0.036
smad2 MAD homolog 2 (Drosophila) 0.036
zgc:55813 zgc:55813 0.035
crestin crestin 0.035
ascl1a achaete-scute complex-like 1a (Drosophila) 0.035
myf5 myogenic factor 5 0.034
gdf11 growth differentiation factor 11 0.034
krt8 keratin 8 0.034
gadd45aa growth arrest and DNA-damage-inducible, alpha, a 0.034
fech ferrochelatase 0.034
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Drosophila melanogaster
Name Description Probability Func Analog Organism
p53 CG33336 gene product from transcript CG33336-RB 0.991
rpr reaper 0.956
Dcp-1 Death caspase-1 0.948
W Wrinkled 0.937
tefu telomere fusion 0.930
Rbf Retinoblastoma-family protein 0.912
Pten CG5671 gene product from transcript CG5671-RB 0.879
park parkin 0.870
sd scalloped 0.799
babo baboon 0.795
Ras85D Ras oncogene at 85D 0.786
dm diminutive 0.761
pr-set7 CG3307 gene product from transcript CG3307-RC 0.743
th thread 0.688
rl rolled 0.679
Src64B Src oncogene at 64B 0.650
NetB Netrin-B 0.618
shi shibire 0.588
aop anterior open 0.577
crol crooked legs 0.517
Atg1 Autophagy-specific gene 1 0.498
jar jaguar 0.439
put punt 0.425
Caf1-180 CG12109 gene product from transcript CG12109-RB 0.408
Akt1 CG4006 gene product from transcript CG4006-RA 0.391
mrn marionette 0.381
HtrA2 CG8464 gene product from transcript CG8464-RA 0.378
scyl scylla 0.361
ex expanded 0.355
Sra-1 specifically Rac1-associated protein 1 0.351
fra frazzled 0.344
dsh dishevelled 0.342
bsk basket 0.335
kibra kibra ortholog 0.319
S6k RPS6-p70-protein kinase 0.316
Tl Toll 0.316
Jafrac1 thioredoxin peroxidase 1 0.289
Hsc70-4 Heat shock protein cognate 4 0.285
jing CG9397 gene product from transcript CG9397-RI 0.276
bchs blue cheese 0.275
awd abnormal wing discs 0.274
loqs loquacious 0.272
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.250
p120ctn Adherens junction protein p120 0.234
so sine oculis 0.233
loco locomotion defects 0.230
Eip93F CG18389 gene product from transcript CG18389-RB 0.223
MED19 Mediator complex subunit 19 0.214
Src42A Src oncogene at 42A 0.202
Arr1 Arrestin 1 0.188
CG11486 CG11486 gene product from transcript CG11486-RG 0.172
Smg5 CG8954 gene product from transcript CG8954-RA 0.170
Nrx-IV Neurexin IV 0.161
Moe Moesin 0.161
nej nejire 0.150
Lam Lamin 0.149
Egfr Epidermal growth factor receptor 0.144
scny scrawny 0.144
argos CG4531 gene product from transcript CG4531-RA 0.142
Dp DP transcription factor 0.141
hep hemipterous 0.141
dj-1beta CG1349 gene product from transcript CG1349-RA 0.138
slmb supernumerary limbs 0.136
grim CG4345 gene product from transcript CG4345-RA 0.134
RagA CG11968 gene product from transcript CG11968-RA 0.133
inaD inactivation no afterpotential D 0.133
CG9425 CG9425 gene product from transcript CG9425-RB 0.127
milt milton 0.124
mib1 mind bomb 1 0.121
ImpL2 Ecdysone-inducible gene L2 0.120
Hph HIF prolyl hydroxylase 0.117
pie pineapple eye 0.117
gig gigas 0.113
Cdc42 CG12530 gene product from transcript CG12530-RA 0.112
spi spitz 0.112
alph alphabet 0.112
CG11347 CG11347 gene product from transcript CG11347-RE 0.110
NFAT NFAT homolog 0.106
Atf-2 Activating transcription factor-2 0.104
Lk6 CG17342 gene product from transcript CG17342-RA 0.102
row relative of woc 0.101
Ephrin CG1862 gene product from transcript CG1862-RA 0.100
shg shotgun 0.098
porin CG6647 gene product from transcript CG6647-RA 0.097
SoxN SoxNeuro 0.096
spn-A spindle A 0.095
Trx-2 thioredoxin-2 0.092
Toll-6 CG7250 gene product from transcript CG7250-RA 0.090
imd immune deficiency 0.089
Akap200 A kinase anchor protein 200 0.088
fz2 frizzled 2 0.088
Prx5 Peroxiredoxin 5 0.087
elav embryonic lethal abnormal vision 0.086
XNP CG4548 gene product from transcript CG4548-RA 0.083
Cat Catalase 0.083
mip130 Myb-interacting protein 130 0.082
Pcaf CG4107 gene product from transcript CG4107-RA 0.082
Dhod Dihydroorotate dehydrogenase 0.082
RhoGEF2 CG9635 gene product from transcript CG9635-RF 0.081
Orc1 Origin recognition complex subunit 1 0.081
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Homo sapiens
Name Description Probability Func Analog Organism
TP53 tumor protein p53 1.000
UBC ubiquitin C 1.000
MDM2 Mdm2 p53 binding protein homolog (mouse) 1.000
BCL2 B-cell CLL/lymphoma 2 1.000
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1.000
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 1.000
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.000
BCL2L1 BCL2-like 1 1.000
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.999
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.999
RB1 retinoblastoma 1 0.999
TRAF6 TNF receptor-associated factor 6 0.999
XIAP X-linked inhibitor of apoptosis 0.999
BIRC3 baculoviral IAP repeat containing 3 0.998
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.997
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.997
TRAF2 TNF receptor-associated factor 2 0.997
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.996
SMAD3 SMAD family member 3 0.996
BRCA1 breast cancer 1, early onset 0.996
CREBBP CREB binding protein 0.996
PML promyelocytic leukemia 0.996
DAXX death-domain associated protein 0.995
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.994
CFLAR CASP8 and FADD-like apoptosis regulator 0.994
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.993
SQSTM1 sequestosome 1 0.993
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.989
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.989
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.989
AR androgen receptor 0.988
FAS Fas (TNF receptor superfamily, member 6) 0.987
FADD Fas (TNFRSF6)-associated via death domain 0.987
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.986
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.985
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.985
MDM4 Mdm4 p53 binding protein homolog (mouse) 0.981
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.981
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.979
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.977
SYVN1 synovial apoptosis inhibitor 1, synoviolin 0.977
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.972
TRAF1 TNF receptor-associated factor 1 0.971
RNF11 ring finger protein 11 0.971
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.970
MAPK8 mitogen-activated protein kinase 8 0.965
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.963
CDC37 cell division cycle 37 homolog (S. cerevisiae) 0.959
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.957
TP53BP2 tumor protein p53 binding protein, 2 0.956
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.949
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.949
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.940
BAX BCL2-associated X protein 0.938
ESR1 estrogen receptor 1 0.937
IL8 interleukin 8 0.937
MAPK1 mitogen-activated protein kinase 1 0.936
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.936
EP300 E1A binding protein p300 0.935
HIPK2 homeodomain interacting protein kinase 2 0.933
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.922
CHEK1 CHK1 checkpoint homolog (S. pombe) 0.921
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.917
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.916
BAD BCL2-associated agonist of cell death 0.915
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.914
BTRC beta-transducin repeat containing 0.912
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.911
S100A4 S100 calcium binding protein A4 0.906
PCNA proliferating cell nuclear antigen 0.905
SP100 SP100 nuclear antigen 0.902
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.897
SKP1 S-phase kinase-associated protein 1 0.893
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.892
TRADD TNFRSF1A-associated via death domain 0.889
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.889
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.887
CAV1 caveolin 1, caveolae protein, 22kDa 0.870
MYD88 myeloid differentiation primary response gene (88) 0.870
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.863
STRN3 striatin, calmodulin binding protein 3 0.862
S100A6 S100 calcium binding protein A6 0.849
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.848
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.847
PIAS4 protein inhibitor of activated STAT, 4 0.832
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.826
GSK3B glycogen synthase kinase 3 beta 0.818
NCOA3 nuclear receptor coactivator 3 0.816
ANXA2 annexin A2 0.813
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.808
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.805
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.798
HDAC1 histone deacetylase 1 0.796
MAPK14 mitogen-activated protein kinase 14 0.796
SMAD7 SMAD family member 7 0.787
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.782
TNF tumor necrosis factor 0.779
FHL2 four and a half LIM domains 2 0.779
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.777
MET met proto-oncogene (hepatocyte growth factor receptor) 0.775
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Rattus norvegicus
Name Description Probability Func Analog Organism
Arpc1b actin related protein 2/3 complex, subunit 1B 0.236
Smad1 SMAD family member 1 0.208
Cd14 CD14 molecule 0.190
S100a8 S100 calcium binding protein A8 0.177
S100a9 S100 calcium binding protein A9 0.177
Plaur plasminogen activator, urokinase receptor 0.171
Krt18 keratin 18 0.146
Jak1 Janus kinase 1 0.123
Smad7 SMAD family member 7 0.120
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.105
Ireb2 iron responsive element binding protein 2 0.089
Ppp1r15a protein phosphatase 1, regulatory (inhibitor) subunit 15A 0.087
Ctdsp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 0.086
Ppib peptidylprolyl isomerase B 0.086
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.083
Nrg1 neuregulin 1 0.076
Timp1 TIMP metallopeptidase inhibitor 1 0.074
Pdia4 protein disulfide isomerase family A, member 4 0.072
Zyx zyxin 0.068
Ccnd3 cyclin D3 0.068
Myc myelocytomatosis oncogene 0.067
Casp3 caspase 3 0.065
Taok1 TAO kinase 1 0.065
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.063
Creb1 cAMP responsive element binding protein 1 0.063
Txnrd1 thioredoxin reductase 1 0.062
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.058
Ech1 enoyl coenzyme A hydratase 1, peroxisomal 0.057
Gpi glucose phosphate isomerase 0.053
Gja5 gap junction protein, alpha 5 0.053
Jak2 Janus kinase 2 0.052
Mapk3 mitogen activated protein kinase 3 0.051
Tp53 tumor protein p53 0.050
Cdkn1a cyclin-dependent kinase inhibitor 1A 0.050
Cd53 Cd53 molecule 0.049
Adora2a adenosine A2a receptor 0.049
Ube2i ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.047
Cd8b CD8b molecule 0.047
Map3k1 mitogen activated protein kinase kinase kinase 1 0.045
Icam1 intercellular adhesion molecule 1 0.045
RT1-Da RT1 class II, locus Da 0.045
Mprip myosin phosphatase Rho interacting protein 0.043
Flt1 FMS-related tyrosine kinase 1 0.043
Lig3 ligase III, DNA, ATP-dependent 0.043
Pyy peptide YY (mapped) 0.041
Gucy2d guanylate cyclase 2d 0.041
Ptprc protein tyrosine phosphatase, receptor type, C 0.040
LOC100364500 RT1 class I, locus CE11-like 0.040
Vegfa vascular endothelial growth factor A 0.040
Ptpn7 protein tyrosine phosphatase, non-receptor type 7 0.040
Tspo translocator protein 0.039
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.038
Sfrs12 splicing factor, arginine/serine-rich 12 0.037
Mcm6 minichromosome maintenance complex component 6 0.037
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.035
Stat3 signal transducer and activator of transcription 3 0.035
Mov10 Moloney leukemia virus 10 0.035
Pdia6 protein disulfide isomerase family A, member 6 0.035
Htr7 5-hydroxytryptamine (serotonin) receptor 7 0.035
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.035
Ccdc102a coiled-coil domain containing 102A 0.034
Pxdn peroxidasin homolog (Drosophila) 0.033
Eif4a2 eukaryotic translation initiation factor 4A, isoform 2 0.032
RT1-Ba RT1 class II, locus Ba 0.032
Ptprs protein tyrosine phosphatase, receptor type, S 0.032
Cryaa crystallin, alpha A 0.031
Rara retinoic acid receptor, alpha 0.031
Gstm5 glutathione S-transferase, mu 5 0.030
Nckap1 NCK-associated protein 1 0.030
Wt1 Wilms tumor 1 0.030
Gpr20 G protein-coupled receptor 20 0.030
Tmod3 tropomodulin 3 0.030
Anxa4 annexin A4 0.030
Hspa9 heat shock protein 9 0.030
Scn1b sodium channel, voltage-gated, type I, beta 0.030
Vat1 vesicle amine transport protein 1 homolog (T californica) 0.029
Kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.029
Ctsc cathepsin C 0.028
Tbxa2r thromboxane A2 receptor 0.028
Ptafr platelet-activating factor receptor 0.028
Adrbk1 adrenergic, beta, receptor kinase 1 0.028
Sirt2 sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) 0.028
Prkcd protein kinase C, delta 0.027
Anxa2 annexin A2 0.027
Dctn4 dynactin 4 0.027
Smc1a structural maintenance of chromosomes 1A 0.026
Klc1 kinesin light chain 1 0.026
Sdc3 syndecan 3 0.026
Mark3 MAP/microtubule affinity-regulating kinase 3 0.026
Ptger2 prostaglandin E receptor 2 (subtype EP2) 0.026
Slc12a4 solute carrier family 12 (potassium/chloride transporters), member 4 0.026
Akr1a1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 0.025
Unc5b unc-5 homolog B (C. elegans) 0.025
Hck hemopoietic cell kinase 0.025
Ralb v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) 0.024
Eef1a2 eukaryotic translation elongation factor 1 alpha 2 0.024
Chrng cholinergic receptor, nicotinic, gamma 0.024
Lcn5 lipocalin 5 0.024
Foxa3 forkhead box A3 0.024
Efna1 ephrin A1 0.024
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism