The network for 'regulation of natural killer cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of natural killer cell differentiation

Any process that modulates the frequency, rate or extent of natural killer cell differentiation.

Name Description Probability Func Analog Organism
Stat3 signal transducer and activator of transcription 3 0.998
Lepr leptin receptor 0.986
Foxp3 forkhead box P3 0.946
Esr1 estrogen receptor 1 (alpha) 0.910
Irf9 interferon regulatory factor 9 0.877
Stat5b signal transducer and activator of transcription 5B 0.771
Il1r1 interleukin 1 receptor, type I 0.759
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.683
Il10 interleukin 10 0.653
Ghr growth hormone receptor 0.648
Pparg peroxisome proliferator activated receptor gamma 0.646
Tlr4 toll-like receptor 4 0.586
Il15ra interleukin 15 receptor, alpha chain 0.576
Myd88 myeloid differentiation primary response gene 88 0.542
Tyro3 TYRO3 protein tyrosine kinase 3 0.480
Prlr prolactin receptor 0.449
Kit kit oncogene 0.447
Il6st interleukin 6 signal transducer 0.440
Stat1 signal transducer and activator of transcription 1 0.376
Il4ra interleukin 4 receptor, alpha 0.329
Tgfb1 transforming growth factor, beta 1 0.293
Igf1 insulin-like growth factor 1 0.286
Ncoa3 nuclear receptor coactivator 3 0.277
Arid1b AT rich interactive domain 1B (SWI-like) 0.277
Nckap1l NCK associated protein 1 like 0.247
Kiss1 KiSS-1 metastasis-suppressor 0.220
Stat5a signal transducer and activator of transcription 5A 0.214
Ptgs2 prostaglandin-endoperoxide synthase 2 0.207
Stat6 signal transducer and activator of transcription 6 0.203
Nfil3 nuclear factor, interleukin 3, regulated 0.202
Trim21 tripartite motif-containing 21 0.196
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.194
Il15 interleukin 15 0.187
Ar androgen receptor 0.159
Il6 interleukin 6 0.146
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.144
Stat2 signal transducer and activator of transcription 2 0.143
Smad3 MAD homolog 3 (Drosophila) 0.141
Lyz2 lysozyme 2 0.135
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.125
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.115
Cd247 CD247 antigen 0.109
Fas Fas (TNF receptor superfamily member 6) 0.104
Spna1 spectrin alpha 1 0.089
Cav1 caveolin 1, caveolae protein 0.078
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.069
Cd44 CD44 antigen 0.068
Trp53 transformation related protein 53 0.052
Jak2 Janus kinase 2 0.049
Apoe apolipoprotein E 0.047
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.045
Irf1 interferon regulatory factor 1 0.045
Tapbp TAP binding protein 0.041
Lep leptin 0.040
Ahr aryl-hydrocarbon receptor 0.040
Rpl18 ribosomal protein L18 0.038
Ifng interferon gamma 0.033
Ifnar2 interferon (alpha and beta) receptor 2 0.032
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.030
Ccl2 chemokine (C-C motif) ligand 2 0.029
Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.028
Rab27a RAB27A, member RAS oncogene family 0.028
Ttc7 tetratricopeptide repeat domain 7 0.027
Il2rg interleukin 2 receptor, gamma chain 0.027
Pnpla2 patatin-like phospholipase domain containing 2 0.026
Gnrh1 gonadotropin releasing hormone 1 0.025
Tnf tumor necrosis factor 0.024
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.024
Zfp36 zinc finger protein 36 0.023
Lck lymphocyte protein tyrosine kinase 0.023
Inpp5d inositol polyphosphate-5-phosphatase D 0.023
Gnb2l1 guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 0.023
Mertk c-mer proto-oncogene tyrosine kinase 0.021
Nedd4l neural precursor cell expressed, developmentally down-regulated gene 4-like 0.020
Irgm1 immunity-related GTPase family M member 1 0.020
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.020
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.019
Il2 interleukin 2 0.019
Adar adenosine deaminase, RNA-specific 0.019
Nos3 nitric oxide synthase 3, endothelial cell 0.019
Pecam1 platelet/endothelial cell adhesion molecule 1 0.019
Ccr9 chemokine (C-C motif) receptor 9 0.019
Csf1 colony stimulating factor 1 (macrophage) 0.017
Ifnar1 interferon (alpha and beta) receptor 1 0.016
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.016
Rps11 ribosomal protein S11 0.016
Bglap bone gamma carboxyglutamate protein 0.016
Rc3h1 RING CCCH (C3H) domains 1 0.015
Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.015
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.015
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.014
Ticam1 toll-like receptor adaptor molecule 1 0.014
Itgal integrin alpha L 0.014
Rps27a ribosomal protein S27A 0.013
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.013
Ldlr low density lipoprotein receptor 0.012
Jak3 Janus kinase 3 0.012
Col1a1 collagen, type I, alpha 1 0.012
Rps19 ribosomal protein S19 0.011
Parp10 poly (ADP-ribose) polymerase family, member 10 0.011
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
GAS6 growth arrest-specific 6 0.991
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.989
INSR insulin receptor 0.973
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.971
AXL AXL receptor tyrosine kinase 0.859
JAK2 Janus kinase 2 0.767
CAV1 caveolin 1, caveolae protein, 22kDa 0.657
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.583
IL15 interleukin 15 0.539
GHR growth hormone receptor 0.491
STAP2 signal transducing adaptor family member 2 0.350
RANBP9 RAN binding protein 9 0.287
IRS1 insulin receptor substrate 1 0.282
STAT5A signal transducer and activator of transcription 5A 0.227
GAB1 GRB2-associated binding protein 1 0.217
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.208
BCAR1 breast cancer anti-estrogen resistance 1 0.152
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.139
IRF1 interferon regulatory factor 1 0.122
PLXNB1 plexin B1 0.116
PLCG1 phospholipase C, gamma 1 0.099
IL2RB interleukin 2 receptor, beta 0.080
STAT5B signal transducer and activator of transcription 5B 0.078
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.056
BCR breakpoint cluster region 0.051
IGF1R insulin-like growth factor 1 receptor 0.046
EPOR erythropoietin receptor 0.046
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.039
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 0.037
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 0.033
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.032
RND1 Rho family GTPase 1 0.031
SPRY2 sprouty homolog 2 (Drosophila) 0.029
IRS2 insulin receptor substrate 2 0.025
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.025
IFNAR2 interferon (alpha, beta and omega) receptor 2 0.024
GRB10 growth factor receptor-bound protein 10 0.024
GBP1 guanylate binding protein 1, interferon-inducible 0.023
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.022
GRIP1 glutamate receptor interacting protein 1 0.020
MAPK8 mitogen-activated protein kinase 8 0.019
TENC1 tensin like C1 domain containing phosphatase (tensin 2) 0.019
SH2B1 SH2B adaptor protein 1 0.019
TRPV6 transient receptor potential cation channel, subfamily V, member 6 0.018
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 0.018
PIK3CA phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.017
PTPRA protein tyrosine phosphatase, receptor type, A 0.017
SPRY4 sprouty homolog 4 (Drosophila) 0.016
IL15RA interleukin 15 receptor, alpha 0.015
PRTFDC1 phosphoribosyl transferase domain containing 1 0.015
MORC3 MORC family CW-type zinc finger 3 0.013
GAB2 GRB2-associated binding protein 2 0.013
NBL1 neuroblastoma, suppression of tumorigenicity 1 0.011
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.010
IFNGR1 interferon gamma receptor 1 0.010
SH2B2 SH2B adaptor protein 2 0.010
LEPR leptin receptor 0.010
TLR3 toll-like receptor 3 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism