The network for 'defense response to gram negative bacterium' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

defense response to gram negative bacterium

Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.

Mus musculus
Name Description Probability Func Analog Organism
Tnf tumor necrosis factor 1.000
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.970
Ccl2 chemokine (C-C motif) ligand 2 0.958
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.921
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.920
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.911
Gbp2 guanylate binding protein 2 0.895
Tlr4 toll-like receptor 4 0.891
Il10 interleukin 10 0.783
Irf1 interferon regulatory factor 1 0.764
Casp1 caspase 1 0.743
Iigp1 interferon inducible GTPase 1 0.728
Trp53 transformation related protein 53 0.722
Il6 interleukin 6 0.709
Nos2 nitric oxide synthase 2, inducible 0.689
B2m beta-2 microglobulin 0.663
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.629
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.623
Gbp7 guanylate binding protein 7 0.597
Igtp interferon gamma induced GTPase 0.530
Ifng interferon gamma 0.501
Tgtp2 T-cell specific GTPase 2 0.483
Gbp3 guanylate binding protein 3 0.471
Nlrp3 NLR family, pyrin domain containing 3 0.470
Csf1 colony stimulating factor 1 (macrophage) 0.448
Stat1 signal transducer and activator of transcription 1 0.429
Pax3 paired box gene 3 0.411
Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 0.398
Ptgs2 prostaglandin-endoperoxide synthase 2 0.365
Atf2 activating transcription factor 2 0.344
Il1b interleukin 1 beta 0.337
Lta lymphotoxin A 0.319
Ifi47 interferon gamma inducible protein 47 0.305
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.304
Myd88 myeloid differentiation primary response gene 88 0.303
Cxcl10 chemokine (C-X-C motif) ligand 10 0.293
Stat3 signal transducer and activator of transcription 3 0.279
Ccl7 chemokine (C-C motif) ligand 7 0.279
Irgm2 immunity-related GTPase family M member 2 0.269
Mmp9 matrix metallopeptidase 9 0.268
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.268
Inhba inhibin beta-A 0.261
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.239
Gbp5 guanylate binding protein 5 0.233
Ccr2 chemokine (C-C motif) receptor 2 0.230
Cxcl13 chemokine (C-X-C motif) ligand 13 0.223
Ccl4 chemokine (C-C motif) ligand 4 0.223
Il1rn interleukin 1 receptor antagonist 0.217
Zeb1 zinc finger E-box binding homeobox 1 0.216
Ltb lymphotoxin B 0.194
H2-Q7 histocompatibility 2, Q region locus 7 0.191
Mefv Mediterranean fever 0.186
Pten phosphatase and tensin homolog 0.186
Irgm1 immunity-related GTPase family M member 1 0.183
Il1r1 interleukin 1 receptor, type I 0.180
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.178
Mmp7 matrix metallopeptidase 7 0.167
Apoe apolipoprotein E 0.163
Mapk14 mitogen-activated protein kinase 14 0.155
Il2rg interleukin 2 receptor, gamma chain 0.154
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.150
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.149
Il6st interleukin 6 signal transducer 0.147
Fgfr1 fibroblast growth factor receptor 1 0.145
Il12b interleukin 12b 0.143
Trim21 tripartite motif-containing 21 0.143
Gm10104 predicted gene 10104 0.142
Cxcl2 chemokine (C-X-C motif) ligand 2 0.133
Socs1 suppressor of cytokine signaling 1 0.128
Sfpi1 SFFV proviral integration 1 0.126
Cd19 CD19 antigen 0.124
Fas Fas (TNF receptor superfamily member 6) 0.120
Bmpr1a bone morphogenetic protein receptor, type 1A 0.119
C3ar1 complement component 3a receptor 1 0.118
Icam1 intercellular adhesion molecule 1 0.116
Csf2 colony stimulating factor 2 (granulocyte-macrophage) 0.114
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.113
Tcf7l1 transcription factor 7-like 1 (T-cell specific, HMG box) 0.113
Selp selectin, platelet 0.112
Cd44 CD44 antigen 0.110
Tgfbr2 transforming growth factor, beta receptor II 0.106
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.106
Cxcl1 chemokine (C-X-C motif) ligand 1 0.105
Gm15315 predicted gene 15315 0.104
Ubd ubiquitin D 0.102
Ccr1 chemokine (C-C motif) receptor 1 0.102
Abcb4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 0.098
Mmp8 matrix metallopeptidase 8 0.096
Lif leukemia inhibitory factor 0.089
Cyld cylindromatosis (turban tumor syndrome) 0.088
Bmp4 bone morphogenetic protein 4 0.084
S1pr2 sphingosine-1-phosphate receptor 2 0.082
Ptgir prostaglandin I receptor (IP) 0.082
Mmp13 matrix metallopeptidase 13 0.081
Ncoa3 nuclear receptor coactivator 3 0.081
Defa17 defensin, alpha, 17 0.080
C3 complement component 3 0.079
Ptprc protein tyrosine phosphatase, receptor type, C 0.079
Clec4d C-type lectin domain family 4, member d 0.079
Irf9 interferon regulatory factor 9 0.076
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
hsp-16.41 Protein HSP-16.41 0.461
dpy-4 Protein DPY-4 0.457
hsp-70 Protein HSP-70 0.388
clec-67 Protein CLEC-67 0.348
col-157 Protein COL-157 0.309
dod-24 Protein DOD-24 0.289
cpr-1 Protein CPR-1 0.280
col-156 Protein COL-156 0.250
col-80 Protein COL-80 0.244
hsp-16.2 Protein HSP-16.2 0.235
rol-6 Protein ROL-6 0.230
CELE_C17H12.8 Protein C17H12.8 0.225
dpy-13 Protein DPY-13 0.225
C34H4.1 Protein C34H4.1 0.194
thn-1 Protein THN-1 0.189
col-43 Protein COL-43 0.183
CELE_C17F4.7 Protein C17F4.7 0.162
col-38 Protein COL-38 0.160
col-98 Protein COL-98 0.159
lys-2 Protein LYS-2 0.156
col-181 Protein COL-181 0.152
hsp-16.1 Protein HSP-16.1 0.149
gst-42 Protein GST-42 0.148
col-154 Protein COL-154 0.147
sqt-2 Protein SQT-2 0.147
F14F9.4 Protein F14F9.4 0.146
daf-14 Protein DAF-14 0.146
col-119 Protein COL-119 0.145
CELE_K08D8.4 Protein K08D8.4 0.144
daf-11 Protein DAF-11 0.127
CELE_F55G11.8 Protein F55G11.8 0.127
col-144 Protein COL-144 0.126
col-104 Protein COL-104 0.126
col-49 Protein COL-49 0.123
F56D2.5 Protein F56D2.5 0.123
col-146 Protein COL-146 0.121
CELE_F55G11.2 Protein F55G11.2 0.120
dpy-7 Protein DPY-7 0.116
col-122 Protein COL-122 0.115
CELE_Y75B8A.4 Protein Y75B8A.4 0.115
col-8 Protein COL-8 0.115
col-133 Protein COL-133 0.115
hsp-16.48 Protein HSP-16.48 0.110
ilys-3 Protein ILYS-3 0.110
col-109 Protein COL-109 0.109
col-140 Protein COL-140 0.104
bli-2 Protein BLI-2 0.104
col-33 Protein COL-33 0.101
F44E5.4 Protein F44E5.4 0.100
unc-54 Protein UNC-54 0.100
col-34 Protein COL-34 0.100
daf-1 Protein DAF-1 0.100
C34H4.2 Protein C34H4.2 0.099
sek-1 Protein SEK-1 0.097
lec-10 Protein LEC-10 0.096
col-17 Protein COL-17 0.095
C34D10.2 Protein C34D10.2 0.093
col-103 Protein COL-103 0.093
col-173 Protein COL-173 0.092
clec-174 Protein CLEC-174 0.091
CELE_ZK896.4 Protein ZK896.4 0.091
lys-7 Protein LYS-7 0.089
col-184 Protein COL-184 0.088
clec-52 Protein CLEC-52 0.088
dpy-8 Protein DPY-8 0.088
CELE_F59B1.8 Protein F59B1.8 0.086
col-110 Protein COL-110 0.085
pgp-6 Protein PGP-6 0.085
C29F3.7 Protein C29F3.7 0.085
sqt-1 Protein SQT-1 0.083
ram-2 Protein RAM-2 0.083
dmd-7 Protein DMD-7 0.083
col-180 Protein COL-180 0.081
col-159 Protein COL-159 0.080
prx-13 Protein PRX-13 0.079
dod-17 Protein DOD-17 0.078
K11H12.4 Protein K11H12.4 0.077
col-2 Protein COL-2 0.077
scl-2 Protein SCL-2 0.077
CELE_K08D8.6 Protein K08D8.6 0.074
col-19 Protein COL-19 0.074
M79.2 Protein M79.2 0.073
lon-3 Protein LON-3 0.073
col-73 Protein COL-73 0.073
tag-244 Protein TAG-244 0.073
C16B8.3 Protein C16B8.3 0.067
CELE_F53C11.1 Protein F53C11.1 0.067
Y94H6A.7 Protein Y94H6A.7 0.066
T23F4.2 Protein T23F4.2 0.065
K10C2.3 Protein K10C2.3 0.065
col-107 Protein COL-107 0.065
col-93 Protein COL-93 0.064
frm-2 Protein FRM-2 0.064
smf-2 Protein SMF-2 0.064
thn-2 Protein THN-2 0.063
pmk-1 Protein PMK-1 0.063
clec-41 Protein CLEC-41 0.063
CELE_C08F11.13 Protein C08F11.13 0.060
col-143 Protein COL-143 0.059
CELE_C14C6.5 Protein C14C6.5 0.059
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.227
atp6ap1 ATPase, H+ transporting, lysosomal accessory protein 1 0.200
sh3gl1b SH3-domain GRB2-like 1b 0.151
emx3 empty spiracles homeobox 3 0.141
crabp2a cellular retinoic acid binding protein 2, a 0.118
igf1rb insulin-like growth factor 1b receptor 0.107
npc1 Niemann-Pick disease, type C1 0.074
bmp7b bone morphogenetic protein 7b 0.072
LOC557072 caspase recruitment domain-containing protein 11-like 0.064
fgfrl1b fibroblast growth factor receptor-like 1b 0.064
tfe3b transcription factor binding to IGHM enhancer 3b 0.059
tp53 tumor protein p53 0.058
fabp6 fatty acid binding protein 6, ileal (gastrotropin) 0.054
ctsl1a cathepsin L, 1 a 0.050
nanos3 nanos homolog 3 0.049
cav1 caveolin 1 0.044
pparg peroxisome proliferator activated receptor gamma 0.044
aqp10b aquaporin 10b 0.044
caspa caspase a 0.043
tlr3 toll-like receptor 3 0.043
aqp8a.2 aquaporin 8a, tandem duplicate 2 0.042
abcc5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.039
copa coatomer protein complex, subunit alpha 0.038
cldn15a claudin 15a 0.038
tlr9 toll-like receptor 9 0.037
notch3 notch homolog 3 0.037
aqp7 aquaporin 7 0.035
lass2 LAG1 homolog, ceramide synthase 2 (S. cerevisiae) 0.035
slc15a1b solute carrier family 15 (oligopeptide transporter), member 1b 0.034
pycard PYD and CARD domain containing 0.031
axin2 axin 2 (conductin, axil) 0.030
duox dual oxidase 0.029
tm4sf4 transmembrane 4 L six family member 4 0.029
nkx6.2 NK6 transcription factor related, locus 2 0.028
bmp2a bone morphogenetic protein 2a 0.028
slc30a7 solute carrier family 30 (zinc transporter), member 7 0.027
etv7 ets variant 7 0.024
rhoub ras homolog gene family, member Ub 0.023
stau2 staufen, RNA binding protein, homolog 2 (Drosophila) 0.023
tm9sf1 transmembrane 9 superfamily member 1 0.023
myh11a myosin, heavy polypeptide 11, smooth muscle a 0.023
aqp4 aquaporin 4 0.023
aqp11 aquaporin 11 0.022
tjp1 tight junction protein 1 (zona occludens 1) 0.022
hgfa hepatocyte growth factor a 0.021
fam3c family with sequence similarity 3, member C 0.021
nr1d2b nuclear receptor subfamily 1, group D, member 2b 0.021
si:ch211-57k11.10 si:ch211-57k11.10 0.021
atp6v0ca ATPase, H+ transporting, lysosomal, V0 subunit c, a 0.021
plekhh1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 0.021
ctsd cathepsin D 0.020
rarga retinoic acid receptor gamma a 0.020
igf1 insulin-like growth factor 1 0.020
runx2a runt-related transcription factor 2a 0.020
tnfrsfa tumor necrosis factor receptor superfamily, member a 0.019
calca calcitonin/calcitonin-related polypeptide, alpha 0.019
cdx1b caudal type homeobox 1 b 0.019
bmp3 bone morphogenetic protein 3 0.018
igf1ra insulin-like growth factor 1a receptor 0.018
epas1b endothelial PAS domain protein 1b 0.018
adipor1a adiponectin receptor 1a 0.017
prdm5 PR domain containing 5 0.017
zgc:100919 zgc:100919 0.017
rpl37 ribosomal protein L37 0.017
dip2c DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.016
pcsk7 proprotein convertase subtilisin/kexin type 7 0.016
fmr1 fragile X mental retardation 1 0.016
prnprs1 prion protein, related sequence 1 0.015
nos2a nitric oxide synthase 2a, inducible 0.015
ins preproinsulin 0.015
itpk1 inositol 1,3,4-triphosphate 5/6 kinase 0.015
LOC100005283 Gig2-like protein DreE 0.015
mtp microsomal triglyceride transfer protein 0.015
zgc:171553 zgc:171553 0.015
il1b interleukin 1, beta and interleukin 1, beta 0.014
smc1al structural maintenance of chromosomes 1A, like 0.014
spns1 spinster homolog 1 (Drosophila) 0.014
gata6 GATA-binding protein 6 0.013
wnt9b wingless-type MMTV integration site family, member 9B 0.013
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.013
LOC100332039 ectonucleotide pyrophosphatase/phosphodiesterase family member 2-like 0.013
fzd5 frizzled homolog 5 0.013
LOC100005232 Gig2-like protein DreD 0.012
nkx2.2a NK2 transcription factor related 2a 0.012
cpne1 copine I 0.012
hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 0.012
rnasel1 ribonuclease like 1 0.012
vtg6 vitellogenin 6 0.012
slc9a3.2 solute carrier family 9 (sodium/hydrogen exchanger), member 3.2 0.012
si:ch73-178d14.1 si:ch73-178d14.1 0.012
prkd1 protein kinase D1 0.012
cdk8 cyclin-dependent kinase 8 0.012
ighz2 immunoglobulin heavy constant zeta2 0.012
elnb elastin b 0.011
ctsc cathepsin C 0.011
cox7c cytochrome c oxidase, subunit VIIc 0.011
tfap2c transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.011
fgf20a fibroblast growth factor 20a 0.011
phf2 PHD finger protein 2 0.011
ptpra protein tyrosine phosphatase, receptor type, A 0.011
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Rel Relish 0.996
AttA Attacin-A 0.991
PGRP-LC Peptidoglycan recognition protein LC 0.967
Jon99Ciii Jonah 99Ciii 0.951
DptB Diptericin B 0.923
fon fondue 0.801
Spn27A Serpin 27A 0.757
Irc Immune-regulated catalase 0.732
grass Gram-positive Specific Serine protease 0.714
Glt Glutactin 0.623
PGRP-SA Peptidoglycan recognition protein SA 0.618
PGRP-SD CG7496 gene product from transcript CG7496-RA 0.586
ird5 immune response deficient 5 0.585
CG17633 CG17633 gene product from transcript CG17633-RA 0.582
Tak1 TGF-beta activated kinase 1 0.581
CG32185 CG32185 gene product from transcript CG32185-RA 0.567
PGRP-SC1a CG14746 gene product from transcript CG14746-RA 0.557
IM18 Immune induced molecule 18 0.553
AttC Attacin-C 0.543
key kenny 0.509
betaTry betaTrypsin 0.493
Mtk Metchnikowin 0.490
spz spatzle 0.479
Sp7 Serine protease 7 0.472
Jon65Ai Jonah 65Ai 0.453
CG6295 CG6295 gene product from transcript CG6295-RA 0.391
Mad Mothers against dpp 0.382
CecC Cecropin C 0.372
CG15917 CG15917 gene product from transcript CG15917-RA 0.363
AGO2 Argonaute 2 0.355
Drs Drosomycin 0.336
Jon65Aiii Jonah 65Aiii 0.331
skpA CG16983 gene product from transcript CG16983-RD 0.326
Pvr PDGF- and VEGF-receptor related 0.321
epsilonTry epsilonTrypsin 0.320
CG18180 CG18180 gene product from transcript CG18180-RA 0.319
Egfr Epidermal growth factor receptor 0.318
PGRP-LB Peptidoglycan recognition protein LB 0.309
LysB Lysozyme B 0.288
Mpk2 CG5475 gene product from transcript CG5475-RB 0.280
PGRP-LF Peptidoglycan recognition protein LF 0.274
SPE Spatzle-Processing Enzyme 0.272
Jafrac1 thioredoxin peroxidase 1 0.263
Dredd Death related ced-3/Nedd2-like protein 0.261
Jon25Bii Jonah 25Bii 0.257
CecA2 Cecropin A2 0.256
LysE Lysozyme E 0.254
Myd88 CG2078 gene product from transcript CG2078-RA 0.247
CG6361 CG6361 gene product from transcript CG6361-RA 0.243
imd immune deficiency 0.238
CG10472 CG10472 gene product from transcript CG10472-RA 0.232
Dro Drosocin 0.227
CG3868 CG3868 gene product from transcript CG3868-RA 0.221
Spn28D Serpin 28D 0.213
Dpt Diptericin 0.213
Amy-d Amylase distal 0.201
Dcr-2 Dicer-2 0.196
CecA1 Cecropin A1 0.192
pirk poor Imd response upon knock-in 0.188
LysD Lysozyme D 0.187
Jon65Aii Jonah 65Aii 0.185
CG9014 CG9014 gene product from transcript CG9014-RA 0.183
CG12581 CG12581 gene product from transcript CG12581-RA 0.179
LysC Lysozyme C 0.178
Nrx-IV Neurexin IV 0.173
MTF-1 Metal response element-binding Transcription Factor-1 0.165
Klc Kinesin light chain 0.162
Ugt35a UDP-glycosyltransferase 35a 0.162
Jon25Biii Jonah 25Biii 0.157
Stam Signal transducing adaptor molecule 0.155
Cyp6a13 CG2397 gene product from transcript CG2397-RA 0.153
CG18594 CG18594 gene product from transcript CG18594-RA 0.151
Kap-alpha3 karyopherin alpha3 0.151
osk oskar 0.150
Sin3A CG8815 gene product from transcript CG8815-RC 0.146
GNBP1 Gram-negative bacteria binding protein 1 0.143
Jon74E Jonah 74E 0.139
Traf4 TNF-receptor-associated factor 4 0.138
Spn1 Serine protease inhibitor 1 0.138
GNBP3 Gram-negative bacteria binding protein 3 0.136
CalpA Calpain-A 0.136
Ag5r2 Antigen 5-related 2 0.129
PGRP-SC2 CG14745 gene product from transcript CG14745-RA 0.128
Duox Dual oxidase 0.127
pie pineapple eye 0.124
Syx7 Syntaxin 7 0.120
MP1 Melanization Protease 1 0.117
Pvf2 PDGF- and VEGF-related factor 2 0.113
Cyp6a23 CG10242 gene product from transcript CG10242-RA 0.112
Thor CG8846 gene product from transcript CG8846-RA 0.112
CG6839 CG6839 gene product from transcript CG6839-RA 0.108
rev7 CG2948 gene product from transcript CG2948-RA 0.108
CG10565 CG10565 gene product from transcript CG10565-RA 0.107
eater CG6124 gene product from transcript CG6124-RB 0.106
Cyp6a9 Cytochrome P450-6a9 0.105
spirit Serine Protease Immune Response Integrator 0.102
PGRP-SB1 CG9681 gene product from transcript CG9681-RA 0.102
Jon99Fi Jonah 99Fi 0.102
TM9SF4 CG7364 gene product from transcript CG7364-RA 0.101
dco discs overgrown 0.100
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.965
MAPK14 mitogen-activated protein kinase 14 0.877
ATF2 activating transcription factor 2 0.624
FGF1 fibroblast growth factor 1 (acidic) 0.580
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.550
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.409
NLRC4 NLR family, CARD domain containing 4 0.320
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.264
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.261
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.202
SMAD4 SMAD family member 4 0.122
CREBBP CREB binding protein 0.116
RNASE4 ribonuclease, RNase A family, 4 0.101
IRAK1 interleukin-1 receptor-associated kinase 1 0.098
DGCR8 DiGeorge syndrome critical region gene 8 0.097
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.096
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.088
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.068
HTT huntingtin 0.067
ENG endoglin 0.066
ANG angiogenin, ribonuclease, RNase A family, 5 0.064
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 0.064
CCL3 chemokine (C-C motif) ligand 3 0.056
IL23A interleukin 23, alpha subunit p19 0.055
IL6 interleukin 6 (interferon, beta 2) 0.051
RIPK2 receptor-interacting serine-threonine kinase 2 0.051
MBD1 methyl-CpG binding domain protein 1 0.049
SNTA1 syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) 0.042
RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) 0.040
ZFP36L1 zinc finger protein 36, C3H type-like 1 0.040
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.039
PLAU plasminogen activator, urokinase 0.038
MAPK1 mitogen-activated protein kinase 1 0.037
MAP3K14 mitogen-activated protein kinase kinase kinase 14 0.035
LY96 lymphocyte antigen 96 0.035
TRAF6 TNF receptor-associated factor 6 0.034
IL6R interleukin 6 receptor 0.032
TCF4 transcription factor 4 0.031
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.031
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 0.029
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa 0.028
UBA1 ubiquitin-like modifier activating enzyme 1 0.027
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 0.027
CAT catalase 0.026
MAPK8 mitogen-activated protein kinase 8 0.025
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.025
PYCARD PYD and CARD domain containing 0.024
ELF4 E74-like factor 4 (ets domain transcription factor) 0.024
HSPB1 heat shock 27kDa protein 1 0.024
LRRK2 leucine-rich repeat kinase 2 0.023
TGFBR1 transforming growth factor, beta receptor 1 0.023
PLAUR plasminogen activator, urokinase receptor 0.022
OSBPL9 oxysterol binding protein-like 9 0.020
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.020
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 0.020
PLAT plasminogen activator, tissue 0.020
CFLAR CASP8 and FADD-like apoptosis regulator 0.020
HDAC7 histone deacetylase 7 0.020
CHD3 chromodomain helicase DNA binding protein 3 0.019
CPNE6 copine VI (neuronal) 0.019
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.019
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.019
THBS1 thrombospondin 1 0.018
FAS Fas (TNF receptor superfamily, member 6) 0.018
IL22 interleukin 22 0.018
DUSP1 dual specificity phosphatase 1 0.018
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 0.018
MYD88 myeloid differentiation primary response gene (88) 0.018
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.018
SMAD5 SMAD family member 5 0.018
SMAD2 SMAD family member 2 0.017
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.017
PYDC2 pyrin domain containing 2 0.016
WRN Werner syndrome, RecQ helicase-like 0.016
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.015
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.015
CD14 CD14 molecule 0.015
SMAD3 SMAD family member 3 0.014
TICAM2 toll-like receptor adaptor molecule 2 0.014
TP73 tumor protein p73 0.014
SEC23A Sec23 homolog A (S. cerevisiae) 0.014
VTN vitronectin 0.014
C4BPA complement component 4 binding protein, alpha 0.013
BAG3 BCL2-associated athanogene 3 0.013
IRF3 interferon regulatory factor 3 0.013
CUL1 cullin 1 0.013
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.013
MEFV Mediterranean fever 0.013
RIN1 Ras and Rab interactor 1 0.013
SOCS3 suppressor of cytokine signaling 3 0.013
DUSP9 dual specificity phosphatase 9 0.013
CP110 CP110 protein 0.013
MKNK1 MAP kinase interacting serine/threonine kinase 1 0.013
SQSTM1 sequestosome 1 0.012
BCL3 B-cell CLL/lymphoma 3 0.012
UBQLN4 ubiquilin 4 0.012
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.012
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.012
CDK8 cyclin-dependent kinase 8 0.012
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.012
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Cybb cytochrome b-245, beta polypeptide 0.024
Tgfb1 transforming growth factor, beta 1 0.022
Cd53 Cd53 molecule 0.022
Mmp12 matrix metallopeptidase 12 0.021
Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 0.021
C8b complement component 8, beta polypeptide 0.021
Adam17 ADAM metallopeptidase domain 17 0.020
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.020
Il1a interleukin 1 alpha 0.020
Arl11 ADP-ribosylation factor-like 11 0.020
Ar androgen receptor 0.019
Casp12 caspase 12 0.019
Ptprc protein tyrosine phosphatase, receptor type, C 0.019
Mpeg1 macrophage expressed 1 0.019
Hnf1b HNF1 homeobox B 0.019
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.019
Il1b interleukin 1 beta 0.018
Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 0.018
Pla1a phospholipase A1 member A 0.018
Pzp pregnancy-zone protein 0.018
Hck hemopoietic cell kinase 0.018
Vegp2 von Ebners gland protein 2 0.018
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.018
Adcy6 adenylate cyclase 6 0.018
Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 0.018
Ccr5 chemokine (C-C motif) receptor 5 0.018
Neurl3 neuralized homolog 3 (Drosophila) 0.018
Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 0.018
Glipr1 GLI pathogenesis-related 1 0.018
Igsf6 immunoglobulin superfamily, member 6 0.018
Pkn3 protein kinase N3 0.018
Plbd2 phospholipase B domain containing 2 0.017
Ftl ferritin, light polypeptide 0.017
Dock8 dedicator of cytokinesis 8 0.017
Myo1c myosin IC 0.017
Itih4 inter alpha-trypsin inhibitor, heavy chain 4 0.017
Rup2 urinary protein 2 0.017
Igf2r insulin-like growth factor 2 receptor 0.017
Slc4a2 solute carrier family 4 (anion exchanger), member 2 0.017
Clec4a1 C-type lectin domain family 4, member a1 0.017
P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 0.017
Amd1 adenosylmethionine decarboxylase 1 0.017
Bsg basigin 0.017
Slfn2 schlafen 2 0.017
Stat3 signal transducer and activator of transcription 3 0.017
Runx1 runt-related transcription factor 1 0.017
Rac2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.017
Lilrb4 leukocyte immunoglobulin-like receptor, subfamily B, member 4 0.017
Bgn biglycan 0.017
Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 0.016
Akt2 v-akt murine thymoma viral oncogene homolog 2 0.016
Casp1 caspase 1 0.016
Sparc secreted protein, acidic, cysteine-rich (osteonectin) 0.016
Znf692 zinc finger protein 692 0.016
Mprip myosin phosphatase Rho interacting protein 0.016
Jak1 Janus kinase 1 0.016
Ms4a6b membrane-spanning 4-domains, subfamily A, member 6B 0.016
Ust5r integral membrane transport protein UST5r 0.016
Met met proto-oncogene 0.016
Cd200r1 CD200 receptor 1 0.016
Snrk SNF related kinase 0.016
Tgm1 transglutaminase 1, K polypeptide 0.016
Grk4 G protein-coupled receptor kinase 4 0.016
Aspg asparaginase homolog (S. cerevisiae) 0.016
Ly6al lymphocyte antigen 6 complex, locus A-like 0.016
Ggcx gamma-glutamyl carboxylase 0.016
Apoa5 apolipoprotein A-V 0.016
Svs3a seminal vesicle secretory protein 3A 0.016
Prelp proline/arginine-rich end leucine-rich repeat protein 0.016
Lig3 ligase III, DNA, ATP-dependent 0.016
Inpp5d inositol polyphosphate-5-phosphatase D 0.016
Cyp3a23/3a1 cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 0.016
Ubtf upstream binding transcription factor, RNA polymerase I 0.016
Gper G protein-coupled estrogen receptor 1 0.016
Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 0.016
Arhgef1 Rho guanine nucleotide exchange factor (GEF) 1 0.016
C5ar1 complement component 5a receptor 1 0.016
Tlr4 toll-like receptor 4 0.016
Slco1a4 solute carrier organic anion transporter family, member 1a4 0.016
Pecam1 platelet/endothelial cell adhesion molecule 1 0.016
Dffb DNA fragmentation factor, beta polypeptide (caspase-activated DNase) 0.016
Pstpip1 proline-serine-threonine phosphatase-interacting protein 1 0.016
Col4a1 collagen, type IV, alpha 1 0.016
Mmp8 matrix metallopeptidase 8 0.016
Mca32 mast cell antigen 32 0.015
Ptgfr prostaglandin F receptor 0.015
Mgp matrix Gla protein 0.015
Phc2 polyhomeotic homolog 2 (Drosophila) 0.015
Agxt2 alanine-glyoxylate aminotransferase 2 0.015
Ces1c carboxylesterase 1C 0.015
Epha3 Eph receptor A3 0.015
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.015
Cd86 CD86 molecule 0.015
RGD1562344 similar to Gm566 protein 0.015
Eltd1 EGF, latrophilin and seven transmembrane domain containing 1 0.015
RGD1309414 similar to KIAA0913 protein 0.015
Nucb1 nucleobindin 1 0.015
Cfi complement factor I 0.015
Ccl2 chemokine (C-C motif) ligand 2 0.015
Ccr3 chemokine (C-C motif) receptor 3 0.015
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism