IMP

Process View

Drosophila melanogaster

28 genes annotated in fly

Multi-species View

regulation of smoothened signaling pathway

GO:0008589

Any process that modulates the frequency, rate or extent of smoothened signaling.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of smoothened signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of smoothened signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
cos	costa	0.451
ci	cubitus interruptus	0.429	Human Zebrafish Mouse
sns	sticks and stones	0.258
hbs	hibris	0.212
ttv	tout-velu	0.183
Ext2	CG8433 gene product from transcript CG8433-RA	0.167	Fly
smo	smoothened	0.154	Zebrafish Mouse
botv	brother of tout-velu	0.149	Fly
hh	hedgehog	0.132	Mouse
pan	pangolin	0.126
Pka-C1	cAMP-dependent protein kinase 1	0.120
Sulf1	Sulfated	0.118
f	forked	0.092
Gp150	CG5820 gene product from transcript CG5820-RA	0.085
fu	fused	0.084
ara	araucan	0.079
pgant3	polypeptide GalNAc transferase 3	0.062
Cul-3	Cullin-3	0.059
fy	fuzzy	0.055	Mouse
fz	frizzled	0.053
Ubx	Ultrabithorax	0.047
inx3	innexin 3	0.047
wdb	widerborst	0.046
wls	wntless	0.046
Pkn	Protein kinase related to protein kinase N	0.046
rst	roughest	0.045
Notum	CG13076 gene product from transcript CG13076-RB	0.043
jeb	jelly belly	0.041
twi	twist	0.040
sfl	sulfateless	0.039
net	CG11450 gene product from transcript CG11450-RB	0.039
noc	no ocelli	0.039
Klp64D	Kinesin-like protein at 64D	0.039
rempA	reduced mechanoreceptor potential A	0.038
tow	target of wingless	0.038
pk	prickle	0.038
yki	yorkie	0.038
vvl	ventral veins lacking	0.038
emc	extra macrochaetae	0.037
Bre1	CG10542 gene product from transcript CG10542-RA	0.036
CG9772	CG9772 gene product from transcript CG9772-RB	0.036
lin	lines	0.036
bnl	branchless	0.036
EloA	Elongin A	0.036
Akt1	CG4006 gene product from transcript CG4006-RA	0.035
Pkd2	Polycystic kidney disease gene-2	0.034
Wnt2	Wnt oncogene analog 2	0.033	Mouse
Ssdp	Sequence-specific single-stranded DNA-binding protein	0.032
dpp	decapentaplegic	0.032
sd	scalloped	0.032
bin	biniou	0.031
boi	brother of iHog	0.031
sgl	sugarless	0.030
kn	knot	0.030
Wnt4	Wnt oncogene analog 4	0.027	Mouse
mib1	mind bomb 1	0.027
rols	rolling pebbles	0.026
PGRP-LC	Peptidoglycan recognition protein LC	0.026
mirr	mirror	0.025
dally	division abnormally delayed	0.025	Mouse Fly
Pp2B-14D	Protein phosphatase 2B at 14D	0.025
HLH54F	CG5005 gene product from transcript CG5005-RA	0.025
frtz	fritz	0.025
lft	lowfat	0.025
kni	knirps	0.025
CG10200	CG10200 gene product from transcript CG10200-RB	0.024
egr	eiger	0.023
wg	wingless	0.023
flr	flare	0.023
fng	fringe	0.023
sim	single-minded	0.023
ft	fat	0.022
nrv2	nervana 2	0.022
nkd	naked cuticle	0.022
hth	homothorax	0.021
Irk2	Inwardly rectifying potassium channel 2	0.021
nompC	no mechanoreceptor potential C	0.021
CG11299	CG11299 gene product from transcript CG11299-RA	0.021
luna	CG33473 gene product from transcript CG33473-RB	0.021
CG9238	CG9238 gene product from transcript CG9238-RA	0.020
Ir	Inwardly rectifying potassium channel	0.020
Indy	I'm not dead yet	0.020
OdsH	Ods-site homeobox	0.020
pnr	pannier	0.020
nct	nicastrin	0.020
CG32372	CG32372 gene product from transcript CG32372-RA	0.020
krz	kurtz	0.019	Zebrafish
zip	zipper	0.019
mew	multiple edematous wings	0.019
nompA	no mechanoreceptor potential A	0.019
CG15730	CG15730 gene product from transcript CG15730-RA	0.019
csw	corkscrew	0.019
elB	elbow B	0.019
CG3308	CG3308 gene product from transcript CG3308-RA	0.019
en	engrailed	0.019
in	inturned	0.019	Mouse
Ubqn	Ubiquilin	0.019
G-oalpha47A	G protein oalpha 47A	0.018
ap	apterous	0.018
CSN7	COP9 complex homolog subunit 7	0.018
Alk	CG8250 gene product from transcript CG8250-RA	0.018
kirre	kin of irre	0.018
argos	CG4531 gene product from transcript CG4531-RA	0.018
ato	atonal	0.017
Rala	Ras-related protein	0.017
inv	invected	0.017
ecd	ecdysoneless	0.017
brk	brinker	0.017
nan	nanchung	0.016
ac	achaete	0.016
m2	E(spl) region transcript m2	0.016
mwh	multiple wing hairs	0.016
ptc	patched	0.016
boss	bride of sevenless	0.016
iav	inactive	0.016
CG13022	CG13022 gene product from transcript CG13022-RB	0.016
elav	embryonic lethal abnormal vision	0.016
Megalin	CG42611 gene product from transcript CG42611-RA	0.016
Cby	Chibby	0.016
Rab14	Rab-protein 14	0.015
eya	eyes absent	0.015
svr	silver	0.015
tilB	touch insensitive larva B	0.015
fz2	frizzled 2	0.015
Sin3A	CG8815 gene product from transcript CG8815-RC	0.015
sog	short gastrulation	0.015	Human
mbl	muscleblind	0.015
RYBP	Ring and YY1 Binding Protein	0.015
Snoo	Sno oncogene	0.015
SoxN	SoxNeuro	0.015
gammaTub23C	gamma-Tubulin at 23C	0.015
CG42251	CG42251 gene product from transcript CG42251-RC	0.015
tefu	telomere fusion	0.015
grh	grainy head	0.015
lok	loki	0.014
CG32556	CG32556 gene product from transcript CG32556-RB	0.014
lbl	ladybird late	0.014
LanB1	CG7123 gene product from transcript CG7123-RA	0.014
if	inflated	0.014
Taf8	TBP-associated factor 8	0.014
Roc1b	CG16988 gene product from transcript CG16988-RA	0.014
Rac2	CG8556 gene product from transcript CG8556-RA	0.014
CG34110	CG34110 gene product from transcript CG34110-RC	0.014
kek5	kekkon5	0.014
MED17	Mediator complex subunit 17	0.013
Cdk4	Cyclin-dependent kinase 4	0.013
jub	Ajuba LIM protein	0.013
CG10741	CG10741 gene product from transcript CG10741-RB	0.013
Rpn11	CG18174 gene product from transcript CG18174-RA	0.013
CG11791	CG11791 gene product from transcript CG11791-RB	0.013
CG7056	CG7056 gene product from transcript CG7056-RA	0.013
dlg1	discs large 1	0.013
sll	slalom	0.013
Bap55	Brahma associated protein 55kD	0.013
Aac11	CG6582 gene product from transcript CG6582-RA	0.013
CG13458	CG13458 gene product from transcript CG13458-RA	0.013
tsg	twisted gastrulation	0.013
ric8a	CG15797 gene product from transcript CG15797-RA	0.013
skd	skuld	0.013
Mnt	CG13316 gene product from transcript CG13316-RD	0.013
Dad	Daughters against dpp	0.013
Sdc	Syndecan	0.013
pygo	pygopus	0.012
Myo31DF	Myosin 31DF	0.012
shn	schnurri	0.012
tin	tinman	0.012
unc	uncoordinated	0.012
disco	disconnected	0.012
Mtl	Mig-2-like	0.012
por	porcupine	0.012
CG13784	CG13784 gene product from transcript CG13784-RC	0.012
fas	faint sausage	0.012
CG9548	CG9548 gene product from transcript CG9548-RA	0.012
CG2107	CG2107 gene product from transcript CG2107-RA	0.012
arr	arrow	0.012
ics	icarus	0.012
rok	Rho-kinase	0.012
Act5C	Actin 5C	0.012
CG9875	CG9875 gene product from transcript CG9875-RA	0.012
cv	crossveinless	0.012
tim	timeless	0.012
magu	CG2264 gene product from transcript CG2264-RD	0.012
dmt	dalmatian	0.012
sha	shavenoid	0.012
CG6304	CG6304 gene product from transcript CG6304-RA	0.012
MED19	Mediator complex subunit 19	0.012
Pkc53E	Protein C kinase 53E	0.011
bic	bicaudal	0.011
uzip	unzipped	0.011
asf1	anti-silencing factor 1	0.011
rumi	CG31152 gene product from transcript CG31152-RA	0.011
nrv1	nervana 1	0.011
sano	serrano	0.011
CG3662	CG3662 gene product from transcript CG3662-RB	0.011
CG1958	CG1958 gene product from transcript CG1958-RA	0.011
dgo	diego	0.011
CG13627	CG13627 gene product from transcript CG13627-RA	0.011
coro	CG9446 gene product from transcript CG9446-RC	0.011
sty	sprouty	0.011
mus101	mutagen-sensitive 101	0.011
Mkp3	Mitogen-activated protein kinase phosphatase 3	0.011
vari	varicose	0.011
CG6398	CG6398 gene product from transcript CG6398-RA	0.011
CG5440	CG5440 gene product from transcript CG5440-RA	0.011
snf	sans fille	0.011
Elongin-C	Elongin C	0.011
sip1	septin interacting protein 1	0.011
Lim3	CG10699 gene product from transcript CG10699-RB	0.011
nau	nautilus	0.011
pyr	pyramus	0.011
RanBPM	Ran-binding protein M	0.011
EDTP	Egg-derived tyrosine phosphatase	0.011
Ac13E	Adenylyl cyclase 35C	0.011
slou	slouch	0.011
cnk	connector enhancer of ksr	0.011
disp	dispatched	0.011
Uch-L3	Ubiquitin C-terminal hydrolase	0.011
msl-2	male-specific lethal 2	0.011
CG42247	CG42247 gene product from transcript CG42247-RC	0.011
jing	CG9397 gene product from transcript CG9397-RI	0.011
rtv	retroactive	0.011
Irk3	Inwardly rectifying potassium channel 3	0.011
CycH	Cyclin H	0.010
CG5050	CG5050 gene product from transcript CG5050-RA	0.010
Dim1	CG3058 gene product from transcript CG3058-RA	0.010
cln3	CG5582 gene product from transcript CG5582-RA	0.010
Cks85A	Cyclin-dependent kinase subunit 85A	0.010
ex	expanded	0.010
Pi3K68D	Phosphotidylinositol 3 kinase 68D	0.010
CG10749	CG10749 gene product from transcript CG10749-RA	0.010
otk	off-track	0.010
dsh	dishevelled	0.010