IMP

Process View

Drosophila melanogaster

19 genes annotated in fly

positive regulation of proteasomal ubiquitin dependent protein catabolic process

Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of proteasomal ubiquitin dependent protein catabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of proteasomal ubiquitin dependent protein catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.684
Rpn6	Proteasome p44.5 subunit	0.466
Mad	Mothers against dpp	0.393
TER94	CG2331 gene product from transcript CG2331-RA	0.392
Pros35	Proteasome 35kD subunit	0.385
CSN4	COP9 complex homolog subunit 4	0.300
Mov34	CG3416 gene product from transcript CG3416-RA	0.246
ida	imaginal discs arrested	0.218
CG30382	CG30382 gene product from transcript CG30382-RB	0.216
CG12321	CG12321 gene product from transcript CG12321-RA	0.215
cdc16	CG6759 gene product from transcript CG6759-RA	0.210
tefu	telomere fusion	0.179
Prp8	pre-mRNA processing factor 8	0.130
UbcD2	Ubiquitin conjugating enzyme 2	0.117
CG13349	CG13349 gene product from transcript CG13349-RA	0.106
fzy	fizzy	0.105
Pros54	Proteasome 54kD subunit	0.103
slmb	supernumerary limbs	0.098
wls	wntless	0.098
Vap-33-1	CG5014 gene product from transcript CG5014-RB	0.095
Tbp-1	Tat-binding protein-1	0.090
Top1	Topoisomerase 1	0.085
kuz	kuzbanian	0.085
Rpn9	CG10230 gene product from transcript CG10230-RB	0.085
Prosbeta3	Proteasome beta3 subunit	0.077
dsh	dishevelled	0.077	Human
cav	caravaggio	0.077
krz	kurtz	0.074
dco	discs overgrown	0.072
wcd	wicked	0.067
CycB	Cyclin B	0.066
Rpt1	CG1341 gene product from transcript CG1341-RA	0.066
Cul-5	Cullin-5	0.064
Mcm10	Sensitized chromosome inheritance modifier 19	0.063
Rpt4	CG3455 gene product from transcript CG3455-RA	0.063
Dcr-2	Dicer-2	0.059
not	non-stop	0.057
Prosbeta1	Proteasome beta1 subunit	0.057
egg	eggless	0.056
Cip4	CG15015 gene product from transcript CG15015-RA	0.055
Uch-L3	Ubiquitin C-terminal hydrolase	0.053
CSN8	COP9 complex homolog subunit 8	0.052
BubR1	Bub1-related kinase	0.051
Pros29	Proteasome 29kD subunit	0.051
gbb	glass bottom boat	0.051
Rpn3	Regulatory particle non-ATPase 3	0.048
Prosbeta7	Proteasome beta7 subunit	0.046
skpA	CG16983 gene product from transcript CG16983-RD	0.043
dlp	dally-like	0.042
Pros26.4	Proteasome 26S subunit subunit 4 ATPase	0.041
arm	armadillo	0.041
CSN1b	COP9 complex homolog subunit 1 b	0.041
l(2)35Bg	lethal (2) 35Bg	0.040
Psf2	CG18013 gene product from transcript CG18013-RA	0.040
disp	dispatched	0.039
Rpt3	CG16916 gene product from transcript CG16916-RA	0.039
CycA	Cyclin A	0.038
l(1)G0007	lethal (1) G0007	0.037
bsk	basket	0.036
Akt1	CG4006 gene product from transcript CG4006-RA	0.036	Mouse
Rpn7	CG5378 gene product from transcript CG5378-RA	0.036
Prosalpha7	Proteasome alpha7 subunit	0.036
Cenp-C	CG31258 gene product from transcript CG31258-RA	0.035
SF2	CG6987 gene product from transcript CG6987-RA	0.034
Pros25	Proteasome 25kD subunit	0.033
Cdc37	CG12019 gene product from transcript CG12019-RA	0.033
Myb	Myb oncogene-like	0.033
CG42251	CG42251 gene product from transcript CG42251-RC	0.032
stan	starry night	0.031
fj	four-jointed	0.031
Mi-2	CG8103 gene product from transcript CG8103-RA	0.030
Pros45	CG1489 gene product from transcript CG1489-RA	0.030
CG5384	CG5384 gene product from transcript CG5384-RA	0.030
Ras85D	Ras oncogene at 85D	0.029
nej	nejire	0.029
Ho	Heme oxygenase	0.028
Rpn1	CG7762 gene product from transcript CG7762-RA	0.028
CSN3	COP9 complex homolog subunit 3	0.028
hpo	hippo	0.027
CG11347	CG11347 gene product from transcript CG11347-RE	0.027
shg	shotgun	0.027
tsr	twinstar	0.027
Klp10A	CG1453 gene product from transcript CG1453-RA	0.026
pim	pimples	0.026
pont	pontin	0.026
InR	Insulin-like receptor	0.026
Prosbeta2	Proteasome beta2 subunit	0.024
Pcaf	CG4107 gene product from transcript CG4107-RA	0.024
Trim9	CG31721 gene product from transcript CG31721-RB	0.024
Uch	Ubiquitin carboxy-terminal hydrolase	0.024
Cks85A	Cyclin-dependent kinase subunit 85A	0.024
fz2	frizzled 2	0.024
jub	Ajuba LIM protein	0.024
fwd	four wheel drive	0.023
Rpn11	CG18174 gene product from transcript CG18174-RA	0.023
CG5555	CG5555 gene product from transcript CG5555-RA	0.023
trc	tricornered	0.023
fz	frizzled	0.022
Cap-G	CG34438 gene product from transcript CG34438-RF	0.022
Med	Medea	0.022
Kap-alpha3	karyopherin alpha3	0.022
TBPH	CG10327 gene product from transcript CG10327-RC	0.022
shtd	shattered	0.022
Su(H)	Suppressor of Hairless	0.021
Cdc27	CG8610 gene product from transcript CG8610-RA	0.021
A3-3	CG11405 gene product from transcript CG11405-RA	0.021
Sgt1	CG9617 gene product from transcript CG9617-RA	0.019
fu	fused	0.019
CG5510	CG5510 gene product from transcript CG5510-RA	0.019
Act5C	Actin 5C	0.019
Bj1	Bj1 protein	0.019
CG11071	CG11071 gene product from transcript CG11071-RA	0.019
brat	brain tumor	0.019
barr	barren	0.018
gpp	grappa	0.018
alphaTub67C	alpha-Tubulin at 67C	0.018
swa	swallow	0.018
Cul-3	Cullin-3	0.018
mts	microtubule star	0.018
dys	dysfusion	0.018
polo	CG12306 gene product from transcript CG12306-RA	0.018	Human
eff	effete	0.017
chb	chromosome bows	0.017
Nuf2	CG8902 gene product from transcript CG8902-RA	0.017
cdc23	CG2508 gene product from transcript CG2508-RA	0.017
ntc	nutcracker	0.017
mats	mob as tumor suppressor	0.017
tan	tantalus	0.017
Sse	Separase	0.017
pho	pleiohomeotic	0.016
pie	pineapple eye	0.016
AGO1	Argonaute-1	0.016
wdb	widerborst	0.015
RYBP	Ring and YY1 Binding Protein	0.015
ari-1	ariadne	0.015
Taspase1	Taspase 1	0.014
Aats-met	Methionyl-tRNA synthetase	0.014
ball	ballchen	0.014
Pink1	PTEN-induced putative kinase 1	0.014
Jra	Jun-related antigen	0.014
ttm50	tiny tim 50	0.014
brp	bruchpilot	0.014
ru	roughoid	0.014
Pten	CG5671 gene product from transcript CG5671-RB	0.014	Human Mouse
CG6859	CG6859 gene product from transcript CG6859-RA	0.013
Fcp1	CG12252 gene product from transcript CG12252-RA	0.013
Pros28.1	Proteasome 28kD subunit 1	0.013
CG8709	CG8709 gene product from transcript CG8709-RK	0.013
Plap	Phospholipase A2 activator protein	0.013
ben	bendless	0.013
dlg1	discs large 1	0.013
Prosalpha5	Proteasome alpha5 subunit	0.012
cmet	CENP-meta	0.012
pasha	partner of drosha	0.012
CG8329	CG8329 gene product from transcript CG8329-RA	0.012
ctp	cut up	0.012
CG17331	CG17331 gene product from transcript CG17331-RA	0.012
poly	CG9829 gene product from transcript CG9829-RB	0.012
step	steppke	0.012
frtz	fritz	0.012
Rpn2	CG11888 gene product from transcript CG11888-RA	0.012
CG5871	CG5871 gene product from transcript CG5871-RA	0.012
dgo	diego	0.012
Doa	Darkener of apricot	0.012
ric8a	CG15797 gene product from transcript CG15797-RA	0.012
coro	CG9446 gene product from transcript CG9446-RC	0.012
CG6961	CG6961 gene product from transcript CG6961-RA	0.011
Z600	CG17962 gene product from transcript CG17962-RA	0.011
DJ-1alpha	CG6646 gene product from transcript CG6646-RA	0.011
Sac1	CG9128 gene product from transcript CG9128-RB	0.011
Tsc1	CG6147 gene product from transcript CG6147-RA	0.011
Pros26	Proteasome 26kD subunit	0.011
mus304	mutagen-sensitive 304	0.011
neur	neuralized	0.011
dbo	diablo	0.011
p47	CG11139 gene product from transcript CG11139-RA	0.011
Mtl	Mig-2-like	0.011
MtnB	Metallothionein B	0.011
Rpb4	CG33520 gene product from transcript CG33520-RF	0.011
plexA	plexin A	0.011
dlt	discs lost	0.011
pygo	pygopus	0.011
Ulp1	CG12359 gene product from transcript CG12359-RA	0.011
stg	string	0.010
CG12001	CG12001 gene product from transcript CG12001-RA	0.010
CG2924	CG2924 gene product from transcript CG2924-RA	0.010
trpml	transient receptor potential mucolipin	0.010
CSN7	COP9 complex homolog subunit 7	0.010
granny-smith	granny smith	0.010
Uba1	Ubiquitin activating enzyme 1	0.010
CG17746	CG17746 gene product from transcript CG17746-RA	0.010
pburs	partner of burs	0.010
CG32556	CG32556 gene product from transcript CG32556-RB	0.010