IMP

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Homo sapiens

24 genes annotated in human

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regulation of endothelial cell apoptotic process

GO:2000351

Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of endothelial cell apoptotic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of endothelial cell apoptotic process" (in gray)

Name	Description	Probability	Func Analog Organism
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.947
SQSTM1	sequestosome 1	0.930
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.912
AKR1C2	aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)	0.906	Human
VEGFA	vascular endothelial growth factor A	0.819
TEK	TEK tyrosine kinase, endothelial	0.800	Mouse
AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)	0.755	Human
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.729
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.727
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.684	Human
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.677
FGA	fibrinogen alpha chain	0.673
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.671
CFLAR	CASP8 and FADD-like apoptosis regulator	0.663
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.649
TAL1	T-cell acute lymphocytic leukemia 1	0.626
FAS	Fas (TNF receptor superfamily, member 6)	0.615
FGB	fibrinogen beta chain	0.611
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.600
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.571
TRAF5	TNF receptor-associated factor 5	0.534
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.510
MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	0.490
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.438
KEAP1	kelch-like ECH-associated protein 1	0.435
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.428	Mouse
AXL	AXL receptor tyrosine kinase	0.425
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.409	Human
AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)	0.360
CDH5	cadherin 5, type 2 (vascular endothelium)	0.351
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.305
LAT	linker for activation of T cells	0.303
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.295
SH3KBP1	SH3-domain kinase binding protein 1	0.292
FGG	fibrinogen gamma chain	0.284
TRAF6	TNF receptor-associated factor 6	0.264
TRAF1	TNF receptor-associated factor 1	0.263
TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy	0.259
SOS1	son of sevenless homolog 1 (Drosophila)	0.240
BCAR1	breast cancer anti-estrogen resistance 1	0.228
TNF	tumor necrosis factor	0.219
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.206
PLAU	plasminogen activator, urokinase	0.180
FYN	FYN oncogene related to SRC, FGR, YES	0.171
EGFR	epidermal growth factor receptor	0.168
PTPRB	protein tyrosine phosphatase, receptor type, B	0.155
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.143
TNFRSF14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.143	Human
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.138
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.135
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.134
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.127
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.126
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.126
FADD	Fas (TNFRSF6)-associated via death domain	0.125
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.121
TRAF3	TNF receptor-associated factor 3	0.116
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.115
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.112
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.110
PLAT	plasminogen activator, tissue	0.109
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.100
BIRC3	baculoviral IAP repeat containing 3	0.099
PRKCZ	protein kinase C, zeta	0.096	Human
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.092
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.086
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.086
TRAF2	TNF receptor-associated factor 2	0.080
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.078
ANGPT2	angiopoietin 2	0.077	Human
CRP	C-reactive protein, pentraxin-related	0.071
VIM	vimentin	0.071
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.069
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.068
SYK	spleen tyrosine kinase	0.067
TRADD	TNFRSF1A-associated via death domain	0.067
S100B	S100 calcium binding protein B	0.065
ENG	endoglin	0.065
ZMYND11	zinc finger, MYND-type containing 11	0.065
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.064
FGFR1	fibroblast growth factor receptor 1	0.062
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.058
LAPTM5	lysosomal protein transmembrane 5	0.057
TGFB1	transforming growth factor, beta 1	0.056
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.055
CDCP1	CUB domain containing protein 1	0.055
ANGPT1	angiopoietin 1	0.054
SH3RF1	SH3 domain containing ring finger 1	0.054
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.052
PECAM1	platelet/endothelial cell adhesion molecule	0.051
LRP1	low density lipoprotein receptor-related protein 1	0.049
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.048
SPRR2A	small proline-rich protein 2A	0.048
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.046
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.045
KITLG	KIT ligand	0.045
TNIP1	TNFAIP3 interacting protein 1	0.043
BCL3	B-cell CLL/lymphoma 3	0.042
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.041
MAP2K5	mitogen-activated protein kinase kinase 5	0.040
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.040
MAPT	microtubule-associated protein tau	0.039
FN1	fibronectin 1	0.039
BGN	biglycan	0.039
KSR1	kinase suppressor of ras 1	0.039
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.039
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.039
CD40	CD40 molecule, TNF receptor superfamily member 5	0.038
FLT4	fms-related tyrosine kinase 4	0.035	Human
PCOLCE	procollagen C-endopeptidase enhancer	0.034
BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	0.033	Human
FYB	FYN binding protein	0.033
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.033
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.032
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.032
COL5A1	collagen, type V, alpha 1	0.032
APP	amyloid beta (A4) precursor protein	0.032
VEGFC	vascular endothelial growth factor C	0.031
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.031
RIPK2	receptor-interacting serine-threonine kinase 2	0.030
SMAD3	SMAD family member 3	0.030
EMILIN1	elastin microfibril interfacer 1	0.030
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.029
CD2	CD2 molecule	0.029
PDGFA	platelet-derived growth factor alpha polypeptide	0.028
TNIP2	TNFAIP3 interacting protein 2	0.028
TTR	transthyretin	0.028
COL6A2	collagen, type VI, alpha 2	0.028
SH2D1A	SH2 domain containing 1A	0.028
ORM1	orosomucoid 1	0.028
PRKCE	protein kinase C, epsilon	0.027
CARD11	caspase recruitment domain family, member 11	0.026
ZNF71	zinc finger protein 71	0.025
ILK	integrin-linked kinase	0.025
PRKCA	protein kinase C, alpha	0.024
IL32	interleukin 32	0.024
CD14	CD14 molecule	0.024
TIMP3	TIMP metallopeptidase inhibitor 3	0.023
KIAA1377	KIAA1377	0.023
C1orf93	chromosome 1 open reading frame 93	0.023
PLCG1	phospholipase C, gamma 1	0.022
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.022
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.022
COL4A1	collagen, type IV, alpha 1	0.022
CD34	CD34 molecule	0.021
TBX2	T-box 2	0.021
ATXN1	ataxin 1	0.021
SPHK1	sphingosine kinase 1	0.021
TRAF3IP2	TRAF3 interacting protein 2	0.020
ZFAND5	zinc finger, AN1-type domain 5	0.020
SOS2	son of sevenless homolog 2 (Drosophila)	0.020
ACTB	actin, beta	0.020
PDGFC	platelet derived growth factor C	0.020
BANP	BTG3 associated nuclear protein	0.020
CLDN5	claudin 5	0.020
NBR1	neighbor of BRCA1 gene 1	0.019
VWF	von Willebrand factor	0.019
TNFSF14	tumor necrosis factor (ligand) superfamily, member 14	0.019	Human
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.019
IGFBP5	insulin-like growth factor binding protein 5	0.019
ACVRL1	activin A receptor type II-like 1	0.018
PGF	placental growth factor	0.018
TECPR1	tectonin beta-propeller repeat containing 1	0.018
APOA1	apolipoprotein A-I	0.018
LDLR	low density lipoprotein receptor	0.018
MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	0.017
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.017
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.017
KLF13	Kruppel-like factor 13	0.017
PEBP4	phosphatidylethanolamine-binding protein 4	0.017
DAG1	dystroglycan 1 (dystrophin-associated glycoprotein 1)	0.017
F2	coagulation factor II (thrombin)	0.017
PDPK1	3-phosphoinositide dependent protein kinase-1	0.017
PICK1	protein interacting with PRKCA 1	0.017
CCDC115	coiled-coil domain containing 115	0.017
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.017
OSMR	oncostatin M receptor	0.017
XIAP	X-linked inhibitor of apoptosis	0.017
STAT5A	signal transducer and activator of transcription 5A	0.016
VTN	vitronectin	0.016
NCF1	neutrophil cytosolic factor 1	0.016
MAP2	microtubule-associated protein 2	0.016
PLAUR	plasminogen activator, urokinase receptor	0.016
PRKCQ	protein kinase C, theta	0.016	Human
MAPK8	mitogen-activated protein kinase 8	0.016
MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)	0.016
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.016
LCK	lymphocyte-specific protein tyrosine kinase	0.016
AEBP1	AE binding protein 1	0.016
FABP4	fatty acid binding protein 4, adipocyte	0.016
TANK	TRAF family member-associated NFKB activator	0.016
NUMB	numb homolog (Drosophila)	0.015
PML	promyelocytic leukemia	0.015
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.015
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.015
CALCRL	calcitonin receptor-like	0.015
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.015
FRZB	frizzled-related protein	0.015
PRKCB	protein kinase C, beta	0.015
TSC2	tuberous sclerosis 2	0.015
COL18A1	collagen, type XVIII, alpha 1	0.014	Mouse
NNMT	nicotinamide N-methyltransferase	0.014
PTPRE	protein tyrosine phosphatase, receptor type, E	0.014
SHANK3	SH3 and multiple ankyrin repeat domains 3	0.014
NRP1	neuropilin 1	0.014
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.014
PPP1R14A	protein phosphatase 1, regulatory (inhibitor) subunit 14A	0.014
ZBTB16	zinc finger and BTB domain containing 16	0.014
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.013
CCL14	chemokine (C-C motif) ligand 14	0.013
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.013
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.013
HDAC6	histone deacetylase 6	0.013
ANGPTL2	angiopoietin-like 2	0.013	Human
IL4R	interleukin 4 receptor	0.013
PLXDC1	plexin domain containing 1	0.013
ROBO4	roundabout homolog 4, magic roundabout (Drosophila)	0.013
CSF1R	colony stimulating factor 1 receptor	0.013	Human
RAI14	retinoic acid induced 14	0.012
GAB2	GRB2-associated binding protein 2	0.012
TNC	tenascin C	0.012
IL15RA	interleukin 15 receptor, alpha	0.012
KLF5	Kruppel-like factor 5 (intestinal)	0.012
GJA4	gap junction protein, alpha 4, 37kDa	0.012
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.012	Human
STAB1	stabilin 1	0.012
A2M	alpha-2-macroglobulin	0.012
ADAM19	ADAM metallopeptidase domain 19	0.012
DARC	Duffy blood group, chemokine receptor	0.012
POLH	polymerase (DNA directed), eta	0.012
BAD	BCL2-associated agonist of cell death	0.012
CSNK1A1	casein kinase 1, alpha 1	0.012
KLF1	Kruppel-like factor 1 (erythroid)	0.012
STK10	serine/threonine kinase 10	0.012
FLNA	filamin A, alpha	0.011
RARRES2	retinoic acid receptor responder (tazarotene induced) 2	0.011
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.011	Human
MCAM	melanoma cell adhesion molecule	0.011
PXN	paxillin	0.011
TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	0.011
ITK	IL2-inducible T-cell kinase	0.011
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.011
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.011
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.011
FASLG	Fas ligand (TNF superfamily, member 6)	0.011
GAB1	GRB2-associated binding protein 1	0.011
ALB	albumin	0.011
STRN	striatin, calmodulin binding protein	0.011
THBD	thrombomodulin	0.011
CAV1	caveolin 1, caveolae protein, 22kDa	0.011
CD93	CD93 molecule	0.011
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.011
TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.011
HAND2	heart and neural crest derivatives expressed 2	0.011
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.011
FBLN2	fibulin 2	0.011
TRIM9	tripartite motif containing 9	0.010
HSD3B7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.010
STC1	stanniocalcin 1	0.010
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.010	Mouse
PCDH12	protocadherin 12	0.010
SLMAP	sarcolemma associated protein	0.010
ASGR2	asialoglycoprotein receptor 2	0.010
BAG1	BCL2-associated athanogene	0.010